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The map label for this gene is atpD

Identifier: 50364930

GI number: 50364930

Start: 138856

End: 140295

Strand: Direct

Name: atpD

Synonym: Mfl115

Alternate gene names: 50364930

Gene position: 138856-140295 (Clockwise)

Preceding gene: 50364929

Following gene: 50364931

Centisome position: 17.51

GC content: 34.03

Gene sequence:

>1440_bases
ATGGCAGCAAAAAAAACGACAAGTAAAAATACTGTTAATTCAGCAAATGGTTTTGTATTCCAAATTTTAGGACCAGTTGT
TGATGTTAAATTTAGCGAAGATAATATTCCTATGATCTATGATGCTTTAGTTGTAGATAATAACGGAGTTGAATTAGTTT
TAGAAGTTGAACAACACATGGGTGATGAAGTTGTTAGAACAATTGCAATGGGACCAACTGAAGGATTAGCAAAAGGTCTT
CCAGTTATTAATACAAACGCTCCAATATTAGCACCAGTTGGTGATGATGTTTTAGGACGTATGTTTAATGTTACAGGGCA
TGCAATTGATGAAAAACCAGAATTCACAGGTAAAAGAATGCCTATCCACCGTGATGCACCAGCTTATGAAGAATTAATTA
CTAATGCTGAAATTTTAGAAACAGGAATTAAAGTTATAGACTTAATGATTCCATTTGCTAAAGGTGGAAAAATTGGATTA
TTCGGTGGAGCCGGAGTTGGTAAAACAGTTTTAATTCAAGAATTAATTAACAATATTGCTAAAGCTCACAGTGGGGTTTC
AGTTTTCGCTGGTGTTGGTGAAAGAACTCGTGAAGGAAATGACCTTTATCATGAATTCATCGAAGCTGGAGTTTTAGATA
AAACAAGTTTAGTATTCGGACAAATGAATGAACCACCAGGTGCACGTATGCGTGTTGCATTAACAGGTTTAACAATTGCT
GAACACTTTAGAGATGAAAAAAACATGGACGTATTATTATTCATTGATAATATTTTCAGATTTACACAAGCAGGTAGTGA
AGTTAGTGCCTTATTAGGACGTATGCCTTCAGCTGTTGGATATCAACCAACTTTATCTACAGAAATGGGTTCACTACAAG
AACGTATTACTTCAACTAATAAAGGATCAATTACATCAGTTCAAGCAGTTTATGTTCCAGCTGATGACTTAACTGACCCA
GCACCTGCAACAACATTTACACACTTAGATGCAAAAATTGTTCTTGACCGTTCAATTGCAAGTTTAGGAATCTATCCTGC
AGTTGATCCACTTTCATCTTCATCAAGAATGTTAGATCCAGAAATTATTGGAGAAGAACATTACAATGTAGCTTTAGGTG
TTCAAGGAACTCTACAAAAATACCAAGATTTACAATCAATCATTGCAATTTTAGGTATGGATGAATTAAGTGCAGAAGAT
AAATTAATTGTCCAAAGAGCACGTAAAATAAGAAACTTCTTATCACAATCATTCTACGTAGGAGAAAAATTTACAGGTCG
TCCTGGACAATATGTAAAAGTATCTGACACAGTAAGATCATTTAAAATGATTCTTGACGGTGAAATGGATGACATTCCAG
AAATCTTGTTCTTATACAAAGGAACAGCTGAAGATGTTATTCAAGCATATAACGAAACAAAAGTTAAAAATAAAAAGTAG

Upstream 100 bases:

>100_bases
TTTAAGTATTCAATATAATCGTGAAAGACAAGCATCAATTACACAAGAAATATCAGAAATTGTTTCTGGTGCTAATGCTT
TAATGGGATAGGAGAAAAAT

Downstream 100 bases:

>100_bases
GTGAATTTAAATGGCAATTAATTTAATAATTACTACTCCAAATGGTAAATTTATAGATAATAAAAAAGTTGATATCATTA
ACTTAAAAACTATTGATGGA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MAAKKTTSKNTVNSANGFVFQILGPVVDVKFSEDNIPMIYDALVVDNNGVELVLEVEQHMGDEVVRTIAMGPTEGLAKGL
PVINTNAPILAPVGDDVLGRMFNVTGHAIDEKPEFTGKRMPIHRDAPAYEELITNAEILETGIKVIDLMIPFAKGGKIGL
FGGAGVGKTVLIQELINNIAKAHSGVSVFAGVGERTREGNDLYHEFIEAGVLDKTSLVFGQMNEPPGARMRVALTGLTIA
EHFRDEKNMDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTNKGSITSVQAVYVPADDLTDP
APATTFTHLDAKIVLDRSIASLGIYPAVDPLSSSSRMLDPEIIGEEHYNVALGVQGTLQKYQDLQSIIAILGMDELSAED
KLIVQRARKIRNFLSQSFYVGEKFTGRPGQYVKVSDTVRSFKMILDGEMDDIPEILFLYKGTAEDVIQAYNETKVKNKK

Sequences:

>Translated_479_residues
MAAKKTTSKNTVNSANGFVFQILGPVVDVKFSEDNIPMIYDALVVDNNGVELVLEVEQHMGDEVVRTIAMGPTEGLAKGL
PVINTNAPILAPVGDDVLGRMFNVTGHAIDEKPEFTGKRMPIHRDAPAYEELITNAEILETGIKVIDLMIPFAKGGKIGL
FGGAGVGKTVLIQELINNIAKAHSGVSVFAGVGERTREGNDLYHEFIEAGVLDKTSLVFGQMNEPPGARMRVALTGLTIA
EHFRDEKNMDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTNKGSITSVQAVYVPADDLTDP
APATTFTHLDAKIVLDRSIASLGIYPAVDPLSSSSRMLDPEIIGEEHYNVALGVQGTLQKYQDLQSIIAILGMDELSAED
KLIVQRARKIRNFLSQSFYVGEKFTGRPGQYVKVSDTVRSFKMILDGEMDDIPEILFLYKGTAEDVIQAYNETKVKNKK
>Mature_478_residues
AAKKTTSKNTVNSANGFVFQILGPVVDVKFSEDNIPMIYDALVVDNNGVELVLEVEQHMGDEVVRTIAMGPTEGLAKGLP
VINTNAPILAPVGDDVLGRMFNVTGHAIDEKPEFTGKRMPIHRDAPAYEELITNAEILETGIKVIDLMIPFAKGGKIGLF
GGAGVGKTVLIQELINNIAKAHSGVSVFAGVGERTREGNDLYHEFIEAGVLDKTSLVFGQMNEPPGARMRVALTGLTIAE
HFRDEKNMDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTNKGSITSVQAVYVPADDLTDPA
PATTFTHLDAKIVLDRSIASLGIYPAVDPLSSSSRMLDPEIIGEEHYNVALGVQGTLQKYQDLQSIIAILGMDELSAEDK
LIVQRARKIRNFLSQSFYVGEKFTGRPGQYVKVSDTVRSFKMILDGEMDDIPEILFLYKGTAEDVIQAYNETKVKNKK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=472, Percent_Identity=63.9830508474576, Blast_Score=599, Evalue=1e-171,
Organism=Homo sapiens, GI19913424, Length=324, Percent_Identity=30.2469135802469, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI19913428, Length=353, Percent_Identity=28.0453257790368, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI19913426, Length=353, Percent_Identity=27.4787535410765, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI50345984, Length=372, Percent_Identity=24.1935483870968, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4757810, Length=372, Percent_Identity=24.1935483870968, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1790170, Length=455, Percent_Identity=66.1538461538461, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1788251, Length=307, Percent_Identity=29.6416938110749, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1790172, Length=310, Percent_Identity=27.0967741935484, Blast_Score=99, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25144756, Length=475, Percent_Identity=64, Blast_Score=611, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI17565854, Length=336, Percent_Identity=29.4642857142857, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17570191, Length=350, Percent_Identity=27.1428571428571, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=430, Percent_Identity=26.2790697674419, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71988080, Length=368, Percent_Identity=24.7282608695652, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=368, Percent_Identity=24.7282608695652, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=329, Percent_Identity=24.0121580547112, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322581, Length=474, Percent_Identity=64.9789029535865, Blast_Score=606, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6319603, Length=392, Percent_Identity=28.3163265306122, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320016, Length=257, Percent_Identity=26.0700389105058, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319370, Length=343, Percent_Identity=23.9067055393586, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24638766, Length=460, Percent_Identity=66.7391304347826, Blast_Score=602, Evalue=1e-172,
Organism=Drosophila melanogaster, GI28574560, Length=474, Percent_Identity=63.9240506329114, Blast_Score=581, Evalue=1e-166,
Organism=Drosophila melanogaster, GI20129479, Length=322, Percent_Identity=29.8136645962733, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24583988, Length=327, Percent_Identity=29.6636085626911, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24583986, Length=327, Percent_Identity=29.6636085626911, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24583984, Length=327, Percent_Identity=29.6636085626911, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24583992, Length=325, Percent_Identity=28, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281361666, Length=354, Percent_Identity=27.683615819209, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24646341, Length=354, Percent_Identity=27.683615819209, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI17136796, Length=354, Percent_Identity=27.683615819209, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=53.8461538461538, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24658560, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_MESFL (Q6F202)

Other databases:

- EMBL:   AE017263
- RefSeq:   YP_053355.1
- ProteinModelPortal:   Q6F202
- SMR:   Q6F202
- GeneID:   2897908
- GenomeReviews:   AE017263_GR
- KEGG:   mfl:Mfl115
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   MFLO265311:MFL115-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01347
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 52154; Mature: 52023

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKKTTSKNTVNSANGFVFQILGPVVDVKFSEDNIPMIYDALVVDNNGVELVLEVEQHM
CCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCEEEEEEEECCCCCEEEEEEHHHC
GDEVVRTIAMGPTEGLAKGLPVINTNAPILAPVGDDVLGRMFNVTGHAIDEKPEFTGKRM
CHHHHHHHHCCCCHHHHCCCCEEECCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCC
PIHRDAPAYEELITNAEILETGIKVIDLMIPFAKGGKIGLFGGAGVGKTVLIQELINNIA
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
KAHSGVSVFAGVGERTREGNDLYHEFIEAGVLDKTSLVFGQMNEPPGARMRVALTGLTIA
HHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHEEECCCCCCCCEEEEEEEHHHHH
EHFRDEKNMDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTN
HHHCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
KGSITSVQAVYVPADDLTDPAPATTFTHLDAKIVLDRSIASLGIYPAVDPLSSSSRMLDP
CCCEEEEEEEEECCCCCCCCCCCCEEEECCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCH
EIIGEEHYNVALGVQGTLQKYQDLQSIIAILGMDELSAEDKLIVQRARKIRNFLSQSFYV
HHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHEEC
GEKFTGRPGQYVKVSDTVRSFKMILDGEMDDIPEILFLYKGTAEDVIQAYNETKVKNKK
CCCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHEECCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AAKKTTSKNTVNSANGFVFQILGPVVDVKFSEDNIPMIYDALVVDNNGVELVLEVEQHM
CCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCEEEEEEEECCCCCEEEEEEHHHC
GDEVVRTIAMGPTEGLAKGLPVINTNAPILAPVGDDVLGRMFNVTGHAIDEKPEFTGKRM
CHHHHHHHHCCCCHHHHCCCCEEECCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCC
PIHRDAPAYEELITNAEILETGIKVIDLMIPFAKGGKIGLFGGAGVGKTVLIQELINNIA
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
KAHSGVSVFAGVGERTREGNDLYHEFIEAGVLDKTSLVFGQMNEPPGARMRVALTGLTIA
HHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHEEECCCCCCCCEEEEEEEHHHHH
EHFRDEKNMDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTN
HHHCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
KGSITSVQAVYVPADDLTDPAPATTFTHLDAKIVLDRSIASLGIYPAVDPLSSSSRMLDP
CCCEEEEEEEEECCCCCCCCCCCCEEEECCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCH
EIIGEEHYNVALGVQGTLQKYQDLQSIIAILGMDELSAEDKLIVQRARKIRNFLSQSFYV
HHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHEEC
GEKFTGRPGQYVKVSDTVRSFKMILDGEMDDIPEILFLYKGTAEDVIQAYNETKVKNKK
CCCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHEECCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA