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The map label for this gene is 50364907

Identifier: 50364907

GI number: 50364907

Start: 112385

End: 114139

Strand: Direct

Name: 50364907

Synonym: Mfl092

Alternate gene names: NA

Gene position: 112385-114139 (Clockwise)

Preceding gene: 50364906

Following gene: 50364909

Centisome position: 14.17

GC content: 27.46

Gene sequence:

>1755_bases
ATGTCAAAAATTAAATTTATGGCACTTGGTGGACAAGATGAAAGAGGAAAAAATCTTTTCGTTTTAGATATCGATGATAA
TCTTTTCATTTTAGATGCCGGTGTTAAATATCCTGATAAAGGAATATTAGGTGTAGATATAGTTACACCAAAACTAGATT
ACTTAAAAAATAATAAACAAAAAATTAAAGGAATTTTTTTAACTAATTCTGCAAGTTACAATATGGGATCTGTTCCATAC
ATTTTAAAAACAATGGATGTTCCAGTATACTGTAATGAAATAACTCAATTAGTCGGTAAAATTAAAATTTCAAGAATGCG
TATTAAAAATACAAAAGACCAAAACTTTGTTGTAGTTAAAGACAAACAAATTTTAGATTTTGGGAAAGTTAAAGTTGAAG
TATTTAGAACTACATCAGCTTCACCTCAATCATATGGTTATGCTTTCCATACTGAAGAAGGAACTATTGTTTATGCTGGA
GACTATATTATTGATGGTAAAGAACAATCTTACTTTTCAACAGATTTTAATCACATAAGTGAAATAGGTAAAAAAGGTGT
ACTTGCATTAATTGCTGATAGTGAATATGCATCAAGAAGCGGTTTCACTGTACCAAATCATAAAATTGAAAATTTTATTT
CAACTTCATTTAAAGAAAAGAAAACTAAAATAGCTATTGGTATTTTTGAAGAAGATATTTTTAAATTAGGTGAAATATGC
ATGGCAGCAAAAGAAAACAATCGTAAAATTGCTGTTTATGGAAGAACAATGACAGAAATTTTAAAATCAAATTTAATCAA
TGAAAATTTACAAATTGTTCCTGAAGACATTATAACTGTTGATGAATACATGAAATCAGAAAATGGTCTTTTAATTATTT
CTGGAACAGGAGATGTTTTATATTCTAAATTAGCAAAAATTGCAACTGGTAATGATGAAGTGGTTGAGTTTACAGAAAAA
GATTTAATTATCTTGGCTACACCACCAGCTCCAGGGGTTGAAAAAAGACATGCACAAATTTTAGATGAATTAGCTAGAAC
TGATGCTAGATTATTAGCGTTAAGTGATAGAAACATTTGATCAATGCACGCTTCATATGAAGATATAAAAGTTTTCACAA
GTATTTTAAATCCAAAATACTTTATTCCTGTTAAATCTTTATTTAAAGATTCTTTAAAAGCAGAAAAGGCTGCAATTGAA
GCTGGAGTTAACGAAAGAAACATTGTTATTTTAGATAATGGTCAAGTAGCAAATATTTCAAAAAACTCTATTTCAATTTC
AGACAAGAAAATAGATATTGGTAATTCTTATGTTGACCAAGCAGGAGTTGGTGATGTTGGAGCTATAGTTTTAAATGAAA
GAAAACTTTTAGCTACAGATGGTGTAATGATTATTGGTGCAACTATTGATTCAAGAAACAAAGAATTAATTTCAATGATA
GATACACAAATGCGTGGAGTTTTATATATTAAAGAGGAAAACCCGATATTTAAAATAATTCAAAAAGAAATCGAATCTCT
TTTAGAACAAGGACAAAGTCAGTTTAAAGAAAACCCAAGTAAGTATGATGTTAATGAAGTTAAAAAAGATATTGCAACAA
GAGTTAGAACTTTAATTAAACAAGAATCAGGTAAACAACCAATTGTTTTAGTAATAGTTAACGAATATGATGGTAAAGAC
TATGTTTTTAAACCAAGAAACAATTCAAACAGAAATTACAAAAATAATAACAATAATAAAAAAGGATCAAATTAA

Upstream 100 bases:

>100_bases
TTATTTCTATGTTAAAATATTTAAAAGCAAAACTGATCTAATCTAACGTTAATCGCGATTAGTGAATATTATATTAATTA
AAATAATAAGGAGAAACTAA

Downstream 100 bases:

>100_bases
TTGATCCTTTTTCTATACTGTATACATTATTATCATAAATACTAAGAATGGTAATAAACAGAATGTGATTGTGTTTCTTC
ATCTAATTAAAACCGCTTCT

Product: putative metallo-beta lactamase hydrolase

Products: NA

Alternate protein names: RNase J2 [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSKIKFMALGGQDERGKNLFVLDIDDNLFILDAGVKYPDKGILGVDIVTPKLDYLKNNKQKIKGIFLTNSASYNMGSVPY
ILKTMDVPVYCNEITQLVGKIKISRMRIKNTKDQNFVVVKDKQILDFGKVKVEVFRTTSASPQSYGYAFHTEEGTIVYAG
DYIIDGKEQSYFSTDFNHISEIGKKGVLALIADSEYASRSGFTVPNHKIENFISTSFKEKKTKIAIGIFEEDIFKLGEIC
MAAKENNRKIAVYGRTMTEILKSNLINENLQIVPEDIITVDEYMKSENGLLIISGTGDVLYSKLAKIATGNDEVVEFTEK
DLIILATPPAPGVEKRHAQILDELARTDARLLALSDRNIWSMHASYEDIKVFTSILNPKYFIPVKSLFKDSLKAEKAAIE
AGVNERNIVILDNGQVANISKNSISISDKKIDIGNSYVDQAGVGDVGAIVLNERKLLATDGVMIIGATIDSRNKELISMI
DTQMRGVLYIKEENPIFKIIQKEIESLLEQGQSQFKENPSKYDVNEVKKDIATRVRTLIKQESGKQPIVLVIVNEYDGKD
YVFKPRNNSNRNYKNNNNNKKGSN

Sequences:

>Translated_584_residues
MSKIKFMALGGQDERGKNLFVLDIDDNLFILDAGVKYPDKGILGVDIVTPKLDYLKNNKQKIKGIFLTNSASYNMGSVPY
ILKTMDVPVYCNEITQLVGKIKISRMRIKNTKDQNFVVVKDKQILDFGKVKVEVFRTTSASPQSYGYAFHTEEGTIVYAG
DYIIDGKEQSYFSTDFNHISEIGKKGVLALIADSEYASRSGFTVPNHKIENFISTSFKEKKTKIAIGIFEEDIFKLGEIC
MAAKENNRKIAVYGRTMTEILKSNLINENLQIVPEDIITVDEYMKSENGLLIISGTGDVLYSKLAKIATGNDEVVEFTEK
DLIILATPPAPGVEKRHAQILDELARTDARLLALSDRNI*SMHASYEDIKVFTSILNPKYFIPVKSLFKDSLKAEKAAIE
AGVNERNIVILDNGQVANISKNSISISDKKIDIGNSYVDQAGVGDVGAIVLNERKLLATDGVMIIGATIDSRNKELISMI
DTQMRGVLYIKEENPIFKIIQKEIESLLEQGQSQFKENPSKYDVNEVKKDIATRVRTLIKQESGKQPIVLVIVNEYDGKD
YVFKPRNNSNRNYKNNNNNKKGSN
>Mature_583_residues
SKIKFMALGGQDERGKNLFVLDIDDNLFILDAGVKYPDKGILGVDIVTPKLDYLKNNKQKIKGIFLTNSASYNMGSVPYI
LKTMDVPVYCNEITQLVGKIKISRMRIKNTKDQNFVVVKDKQILDFGKVKVEVFRTTSASPQSYGYAFHTEEGTIVYAGD
YIIDGKEQSYFSTDFNHISEIGKKGVLALIADSEYASRSGFTVPNHKIENFISTSFKEKKTKIAIGIFEEDIFKLGEICM
AAKENNRKIAVYGRTMTEILKSNLINENLQIVPEDIITVDEYMKSENGLLIISGTGDVLYSKLAKIATGNDEVVEFTEKD
LIILATPPAPGVEKRHAQILDELARTDARLLALSDRNI*SMHASYEDIKVFTSILNPKYFIPVKSLFKDSLKAEKAAIEA
GVNERNIVILDNGQVANISKNSISISDKKIDIGNSYVDQAGVGDVGAIVLNERKLLATDGVMIIGATIDSRNKELISMID
TQMRGVLYIKEENPIFKIIQKEIESLLEQGQSQFKENPSKYDVNEVKKDIATRVRTLIKQESGKQPIVLVIVNEYDGKDY
VFKPRNNSNRNYKNNNNNKKGSN

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 65212; Mature: 65080

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIKFMALGGQDERGKNLFVLDIDDNLFILDAGVKYPDKGILGVDIVTPKLDYLKNNKQ
CCCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCCEEEEEEECCCHHHHCCCCE
KIKGIFLTNSASYNMGSVPYILKTMDVPVYCNEITQLVGKIKISRMRIKNTKDQNFVVVK
EEEEEEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHEEEEEEECCCCCCCEEEEE
DKQILDFGKVKVEVFRTTSASPQSYGYAFHTEEGTIVYAGDYIIDGKEQSYFSTDFNHIS
CCCEECCCCEEEEEEEECCCCCCCCCEEEECCCCEEEEECCEEECCCCCCEECCCHHHHH
EIGKKGVLALIADSEYASRSGFTVPNHKIENFISTSFKEKKTKIAIGIFEEDIFKLGEIC
HHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHH
MAAKENNRKIAVYGRTMTEILKSNLINENLQIVPEDIITVDEYMKSENGLLIISGTGDVL
HHHCCCCCEEEEECCHHHHHHHHHHCCCCCEECCHHHEEHHHHHCCCCCEEEEECCCHHH
YSKLAKIATGNDEVVEFTEKDLIILATPPAPGVEKRHAQILDELARTDARLLALSDRNIS
HHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCEE
MHASYEDIKVFTSILNPKYFIPVKSLFKDSLKAEKAAIEAGVNERNIVILDNGQVANISK
EECCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECC
NSISISDKKIDIGNSYVDQAGVGDVGAIVLNERKLLATDGVMIIGATIDSRNKELISMID
CEEEECCCEEECCCCHHCCCCCCCEEEEEECCCEEEEECCEEEEEEEECCCCHHHHHHHH
TQMRGVLYIKEENPIFKIIQKEIESLLEQGQSQFKENPSKYDVNEVKKDIATRVRTLIKQ
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ESGKQPIVLVIVNEYDGKDYVFKPRNNSNRNYKNNNNNKKGSN
CCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKIKFMALGGQDERGKNLFVLDIDDNLFILDAGVKYPDKGILGVDIVTPKLDYLKNNKQ
CCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCCEEEEEEECCCHHHHCCCCE
KIKGIFLTNSASYNMGSVPYILKTMDVPVYCNEITQLVGKIKISRMRIKNTKDQNFVVVK
EEEEEEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHEEEEEEECCCCCCCEEEEE
DKQILDFGKVKVEVFRTTSASPQSYGYAFHTEEGTIVYAGDYIIDGKEQSYFSTDFNHIS
CCCEECCCCEEEEEEEECCCCCCCCCEEEECCCCEEEEECCEEECCCCCCEECCCHHHHH
EIGKKGVLALIADSEYASRSGFTVPNHKIENFISTSFKEKKTKIAIGIFEEDIFKLGEIC
HHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHH
MAAKENNRKIAVYGRTMTEILKSNLINENLQIVPEDIITVDEYMKSENGLLIISGTGDVL
HHHCCCCCEEEEECCHHHHHHHHHHCCCCCEECCHHHEEHHHHHCCCCCEEEEECCCHHH
YSKLAKIATGNDEVVEFTEKDLIILATPPAPGVEKRHAQILDELARTDARLLALSDRNIS
HHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCEE
MHASYEDIKVFTSILNPKYFIPVKSLFKDSLKAEKAAIEAGVNERNIVILDNGQVANISK
EECCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECC
NSISISDKKIDIGNSYVDQAGVGDVGAIVLNERKLLATDGVMIIGATIDSRNKELISMID
CEEEECCCEEECCCCHHCCCCCCCEEEEEECCCEEEEECCEEEEEEEECCCCHHHHHHHH
TQMRGVLYIKEENPIFKIIQKEIESLLEQGQSQFKENPSKYDVNEVKKDIATRVRTLIKQ
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ESGKQPIVLVIVNEYDGKDYVFKPRNNSNRNYKNNNNNKKGSN
CCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA