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The map label for this gene is dnaC [H]

Identifier: 50364899

GI number: 50364899

Start: 105090

End: 106436

Strand: Direct

Name: dnaC [H]

Synonym: Mfl084

Alternate gene names: 50364899

Gene position: 105090-106436 (Clockwise)

Preceding gene: 50364898

Following gene: 50364900

Centisome position: 13.25

GC content: 29.7

Gene sequence:

>1347_bases
ATGAGTAGAAAAGATATGAGCGAAAACAATTTACATTCAGTTGAAAAGATGGTTCTTGCTATTGCGATGCATTCTCCAAA
TGCGCTGCCAGATATAATGACAGGTTTGGTTGCTGATGACTTTTTAGATTCAACCCACAAAATAATTTTTCAAGGGATAA
TAGAATTACATTCTCAAAGCAAAGAAGTTACTATTAGTTCTGTAGCAAACCAAATTGAAAAAAAAGGAAACTTGGAGTCA
ATTGGTGGAATTCAAAGACTTCAAGATATTGCTTTAGACTTCTTTTCAGATGAAGGAATTGAAAACTTCATAGAAGATAT
TTTTTACGCTAGTTCTTCAAGAAAATTTGATGCAGCTTTAAGAAGAGTTCAAAATTTAAGAAGAGAAGAACAAATGGATA
TTGAATCATCAATTAACGAAATTCAAAAAGAATTATTAAAAATAGATCTTAATGCACAAAAAAACGATGTTCAAAGTATT
CATGCCTCAACTGAGTCATTAATTAAAAAAATTCAAGAGTTGGAAAAAAGAAGTGAAACTTTAACAGGTATACCAACTGA
TCTTTTTGAGTTAGATGAAATAACTTCAGGTCTTCAAGAAGGAGATTTAATTATTTTAGCAGCTCGTCCAAGTATGGGTA
AAACAGCTTTTGCCTTAAACTTAGCTTACAATGCGGCAAGACATAAAAATGGAGTTGCTGTTTTCTCATTAGAAATGCCA
GCTGAACAATTGACACAAAGAATAATGACAATGGTTTCAAAAATAGATTCAAAAAAATTAAGAACTGGTAAAAATATTTC
TAAAGCTGAATGAAGTAATCTTTTAGCTTCAAAAGAAATTGTTTCACAATTACCAATTTATATTGATGATACTCCTGGAA
TAACTGTTCAACAAATTCAATCAAAATTATATAAATTAAAAAGAGATCATGATGTTAAATTTTGTGTTGTGGACTACCTT
CAATTAATTAGTTCAACAAACGGCTCAGCAGATAGACAAAATGAAATATCAAATATTTCTCGTCAACTAAAAAGAGTTGC
CAGAGAATTAAGAATACCTATTGTTTGTTTATCACAACTTTCAAGAAGTGTTGAAAAACGTGAAGATAAAAGACCTATAA
TGTCTGACTTACGTGATTCTGGTGCTATTGAGCAAGATGCTGATATTATTATGTTTTTATATCGAGATGATTATTACAAA
CATAAAGACGGTAATGAAGAAGAAAATAAAATTGTTGATCAAGTAAGTGCTACAGATTTAATTCTTTCAAAACATAGAAA
TGGTGCTACTGGAACTATCAATATATTATTTGATAAAAGTCATGGAAAATTCATGGATAAAGGGTAA

Upstream 100 bases:

>100_bases
AACTTTAAAAATCTAAATCAAATAGGATTACATTATATAGTTATAAAATTAGGTTTTGGTATTGAAGCAAAATTAAAAGT
AGAAATTCAAGGGGTATAAA

Downstream 100 bases:

>100_bases
TTGAAATGGGAGAAATTCCATTTTTTTTGTTATAATTATACAAGATATGCTCATAAGGAGGATTTATGAAGAAATTATTA
TCTATTATTACAGCATTAAC

Product: DNA replication priming helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MSRKDMSENNLHSVEKMVLAIAMHSPNALPDIMTGLVADDFLDSTHKIIFQGIIELHSQSKEVTISSVANQIEKKGNLES
IGGIQRLQDIALDFFSDEGIENFIEDIFYASSSRKFDAALRRVQNLRREEQMDIESSINEIQKELLKIDLNAQKNDVQSI
HASTESLIKKIQELEKRSETLTGIPTDLFELDEITSGLQEGDLIILAARPSMGKTAFALNLAYNAARHKNGVAVFSLEMP
AEQLTQRIMTMVSKIDSKKLRTGKNISKAEWSNLLASKEIVSQLPIYIDDTPGITVQQIQSKLYKLKRDHDVKFCVVDYL
QLISSTNGSADRQNEISNISRQLKRVARELRIPIVCLSQLSRSVEKREDKRPIMSDLRDSGAIEQDADIIMFLYRDDYYK
HKDGNEEENKIVDQVSATDLILSKHRNGATGTINILFDKSHGKFMDKG

Sequences:

>Translated_448_residues
MSRKDMSENNLHSVEKMVLAIAMHSPNALPDIMTGLVADDFLDSTHKIIFQGIIELHSQSKEVTISSVANQIEKKGNLES
IGGIQRLQDIALDFFSDEGIENFIEDIFYASSSRKFDAALRRVQNLRREEQMDIESSINEIQKELLKIDLNAQKNDVQSI
HASTESLIKKIQELEKRSETLTGIPTDLFELDEITSGLQEGDLIILAARPSMGKTAFALNLAYNAARHKNGVAVFSLEMP
AEQLTQRIMTMVSKIDSKKLRTGKNISKAE*SNLLASKEIVSQLPIYIDDTPGITVQQIQSKLYKLKRDHDVKFCVVDYL
QLISSTNGSADRQNEISNISRQLKRVARELRIPIVCLSQLSRSVEKREDKRPIMSDLRDSGAIEQDADIIMFLYRDDYYK
HKDGNEEENKIVDQVSATDLILSKHRNGATGTINILFDKSHGKFMDKG
>Mature_447_residues
SRKDMSENNLHSVEKMVLAIAMHSPNALPDIMTGLVADDFLDSTHKIIFQGIIELHSQSKEVTISSVANQIEKKGNLESI
GGIQRLQDIALDFFSDEGIENFIEDIFYASSSRKFDAALRRVQNLRREEQMDIESSINEIQKELLKIDLNAQKNDVQSIH
ASTESLIKKIQELEKRSETLTGIPTDLFELDEITSGLQEGDLIILAARPSMGKTAFALNLAYNAARHKNGVAVFSLEMPA
EQLTQRIMTMVSKIDSKKLRTGKNISKAE*SNLLASKEIVSQLPIYIDDTPGITVQQIQSKLYKLKRDHDVKFCVVDYLQ
LISSTNGSADRQNEISNISRQLKRVARELRIPIVCLSQLSRSVEKREDKRPIMSDLRDSGAIEQDADIIMFLYRDDYYKH
KDGNEEENKIVDQVSATDLILSKHRNGATGTINILFDKSHGKFMDKG

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=446, Percent_Identity=34.9775784753363, Blast_Score=244, Evalue=9e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50382; Mature: 50251

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKDMSENNLHSVEKMVLAIAMHSPNALPDIMTGLVADDFLDSTHKIIFQGIIELHSQS
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KEVTISSVANQIEKKGNLESIGGIQRLQDIALDFFSDEGIENFIEDIFYASSSRKFDAAL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHH
RRVQNLRREEQMDIESSINEIQKELLKIDLNAQKNDVQSIHASTESLIKKIQELEKRSET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGIPTDLFELDEITSGLQEGDLIILAARPSMGKTAFALNLAYNAARHKNGVAVFSLEMP
HCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHCCCCEEEEEECCC
AEQLTQRIMTMVSKIDSKKLRTGKNISKAESNLLASKEIVSQLPIYIDDTPGITVQQIQS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
KLYKLKRDHDVKFCVVDYLQLISSTNGSADRQNEISNISRQLKRVARELRIPIVCLSQLS
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RSVEKREDKRPIMSDLRDSGAIEQDADIIMFLYRDDYYKHKDGNEEENKIVDQVSATDLI
HHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
LSKHRNGATGTINILFDKSHGKFMDKG
HHHCCCCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SRKDMSENNLHSVEKMVLAIAMHSPNALPDIMTGLVADDFLDSTHKIIFQGIIELHSQS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KEVTISSVANQIEKKGNLESIGGIQRLQDIALDFFSDEGIENFIEDIFYASSSRKFDAAL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHH
RRVQNLRREEQMDIESSINEIQKELLKIDLNAQKNDVQSIHASTESLIKKIQELEKRSET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGIPTDLFELDEITSGLQEGDLIILAARPSMGKTAFALNLAYNAARHKNGVAVFSLEMP
HCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHCCCCEEEEEECCC
AEQLTQRIMTMVSKIDSKKLRTGKNISKAESNLLASKEIVSQLPIYIDDTPGITVQQIQS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
KLYKLKRDHDVKFCVVDYLQLISSTNGSADRQNEISNISRQLKRVARELRIPIVCLSQLS
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RSVEKREDKRPIMSDLRDSGAIEQDADIIMFLYRDDYYKHKDGNEEENKIVDQVSATDLI
HHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
LSKHRNGATGTINILFDKSHGKFMDKG
HHHCCCCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]