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The map label for this gene is bglC [H]

Identifier: 50364826

GI number: 50364826

Start: 14854

End: 16248

Strand: Direct

Name: bglC [H]

Synonym: Mfl011

Alternate gene names: 50364826

Gene position: 14854-16248 (Clockwise)

Preceding gene: 50364825

Following gene: 50364827

Centisome position: 1.87

GC content: 28.53

Gene sequence:

>1395_bases
ATGAATAAATTTCCAAAAGATTTTTTATGAGGTGCGTCAACAAGCGCTTATCAATTTGAAGGAGCTATTAAACAAGGTGG
TAAAGTAAGTTCTATTATGGATAGATTTGACGAACAGCCGTCATATCCAAAAGGAATAACAGGTTTTAAAGAGGCTTCAG
ATCACTATAATCATTGAAAAGAAGATGTAAAACTTATGTCTGAAATGGGATTCAAATCATATAGATTTTCGATTTCATGA
CCAAGAATTATTAAAAATAAGGAAGGTGAAATTAATAAAGAAGGAATTAAATTTTATAATGATTTAATTGATGAACTTTT
TAAACATAAAATTGAACCAATAGTGACAATGTTTCATTTTGATATACCAGATTTTATCCAAGAAATTGGTGGTGTATGTA
CTAACGAATTTACAAAACAATTTGAAATTTACTCAGAAGTTTTATTTAAAAATTTTGGTTCAAAAATTAAATATTGATTA
ACAATAAACGAATTGAATATGTTTGCTCTAGCAGGACAAATTATTGGTGTTGTCCCAAGCGATCAAAAGATTAATTCATG
ACAATTAATGCACCATTTAAATGTTGCACAAGCTAAAGCTATTGTATTGTGTAGAAAAATTTGTCCATCTGCAAAAATAG
GGCCTGCGCCAAATATTTCAACTGTTTACCCAGATTCAAATAAACCATTAGACTATGTAGCAAAATTAAATTTAGACATG
GTTAGAAATTGAGTTTACTTAGATATTGTTTGTAGAGGTGAATATAGTCCAATATTTATTAATGGATTAAAAAAAATGGG
ACTTGAAATTACTATCACGGAGGAAGAAAAACAAATTCTTAAAAATTCTAAACCTGATTTTATTGCATTTAATTATTATT
CAACAATGACTGTTAAAATGCCTACTGAAGAAAGTTTAAAGAATACAAAAAAAGATCAACAACAAGGATTATCTATGCCA
GGTTTTGGCGAAAGTGTTAAGAATGATAAACTTGAAAAAACTCAATTTGGTTGAGAGATTGACCCAGTTGGTTTTAGAAA
TACATTAAGAGAAGTTTATGACAGATATCAACTTCCAATCATGATAACAGAAAATGGAATCGGTGCAAGAGATGTTCTTG
AAGAAGACGGAAAAATTCATGATAACTACAGAATAGAATACTATGAAAAACACATACAGCAAATGGCTCTTGCAATTGCT
GATGGAGTTGAAATGATTGGTTACATGCCTTGAAGTGCTATCGACTTAGTTTCGACTCACGAAGGTATTTCAAAAAGATA
TGGATTTGTATATGTTAACAGAGATGAATTTGATTTAAAAGATATGAAAAGATATAAAAAAGATAGTTTTCATTGATATA
AAGAATTAATTAAAAATAATGGTGAAAATATTTAG

Upstream 100 bases:

>100_bases
ATAATTTAATAGATTGGTGTAAAAAATTAAATTAAAACGAAAAAAGAATTTTAAAAATATAAGAAATATTAACGTTTTAT
TATTTATGAAGGAGTAAGAA

Downstream 100 bases:

>100_bases
AGGAGATAGATACATATGACTAAAAAATTAGAATTTCCAAGCAATTTTTTATGAGGTGGTGCTACTGCAGCATCTCAAAT
AGAAGGTGCTTATAATGTAG

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNKFPKDFLWGASTSAYQFEGAIKQGGKVSSIMDRFDEQPSYPKGITGFKEASDHYNHWKEDVKLMSEMGFKSYRFSISW
PRIIKNKEGEINKEGIKFYNDLIDELFKHKIEPIVTMFHFDIPDFIQEIGGVCTNEFTKQFEIYSEVLFKNFGSKIKYWL
TINELNMFALAGQIIGVVPSDQKINSWQLMHHLNVAQAKAIVLCRKICPSAKIGPAPNISTVYPDSNKPLDYVAKLNLDM
VRNWVYLDIVCRGEYSPIFINGLKKMGLEITITEEEKQILKNSKPDFIAFNYYSTMTVKMPTEESLKNTKKDQQQGLSMP
GFGESVKNDKLEKTQFGWEIDPVGFRNTLREVYDRYQLPIMITENGIGARDVLEEDGKIHDNYRIEYYEKHIQQMALAIA
DGVEMIGYMPWSAIDLVSTHEGISKRYGFVYVNRDEFDLKDMKRYKKDSFHWYKELIKNNGENI

Sequences:

>Translated_464_residues
MNKFPKDFL*GASTSAYQFEGAIKQGGKVSSIMDRFDEQPSYPKGITGFKEASDHYNH*KEDVKLMSEMGFKSYRFSIS*
PRIIKNKEGEINKEGIKFYNDLIDELFKHKIEPIVTMFHFDIPDFIQEIGGVCTNEFTKQFEIYSEVLFKNFGSKIKY*L
TINELNMFALAGQIIGVVPSDQKINS*QLMHHLNVAQAKAIVLCRKICPSAKIGPAPNISTVYPDSNKPLDYVAKLNLDM
VRN*VYLDIVCRGEYSPIFINGLKKMGLEITITEEEKQILKNSKPDFIAFNYYSTMTVKMPTEESLKNTKKDQQQGLSMP
GFGESVKNDKLEKTQFG*EIDPVGFRNTLREVYDRYQLPIMITENGIGARDVLEEDGKIHDNYRIEYYEKHIQQMALAIA
DGVEMIGYMP*SAIDLVSTHEGISKRYGFVYVNRDEFDLKDMKRYKKDSFH*YKELIKNNGENI
>Mature_464_residues
MNKFPKDFL*GASTSAYQFEGAIKQGGKVSSIMDRFDEQPSYPKGITGFKEASDHYNH*KEDVKLMSEMGFKSYRFSIS*
PRIIKNKEGEINKEGIKFYNDLIDELFKHKIEPIVTMFHFDIPDFIQEIGGVCTNEFTKQFEIYSEVLFKNFGSKIKY*L
TINELNMFALAGQIIGVVPSDQKINS*QLMHHLNVAQAKAIVLCRKICPSAKIGPAPNISTVYPDSNKPLDYVAKLNLDM
VRN*VYLDIVCRGEYSPIFINGLKKMGLEITITEEEKQILKNSKPDFIAFNYYSTMTVKMPTEESLKNTKKDQQQGLSMP
GFGESVKNDKLEKTQFG*EIDPVGFRNTLREVYDRYQLPIMITENGIGARDVLEEDGKIHDNYRIEYYEKHIQQMALAIA
DGVEMIGYMP*SAIDLVSTHEGISKRYGFVYVNRDEFDLKDMKRYKKDSFH*YKELIKNNGENI

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=491, Percent_Identity=29.3279022403259, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI13273313, Length=486, Percent_Identity=27.9835390946502, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI32481206, Length=485, Percent_Identity=28.659793814433, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI24497614, Length=491, Percent_Identity=27.4949083503055, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI28376633, Length=474, Percent_Identity=25.9493670886076, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI2367174, Length=483, Percent_Identity=37.2670807453416, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI2367270, Length=477, Percent_Identity=36.2683438155136, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1789070, Length=489, Percent_Identity=34.7648261758691, Blast_Score=254, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI17552856, Length=483, Percent_Identity=31.4699792960663, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17539390, Length=485, Percent_Identity=29.6907216494845, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21356577, Length=494, Percent_Identity=26.5182186234818, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 52053; Mature: 52053

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFPKDFLGASTSAYQFEGAIKQGGKVSSIMDRFDEQPSYPKGITGFKEASDHYNHKED
CCCCCCHHHCCCCCHHEECHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHH
VKLMSEMGFKSYRFSISPRIIKNKEGEINKEGIKFYNDLIDELFKHKIEPIVTMFHFDIP
HHHHHHCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DFIQEIGGVCTNEFTKQFEIYSEVLFKNFGSKIKYLTINELNMFALAGQIIGVVPSDQKI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHEEECCCCHHH
NSQLMHHLNVAQAKAIVLCRKICPSAKIGPAPNISTVYPDSNKPLDYVAKLNLDMVRNVY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHCCHHHHHHHH
LDIVCRGEYSPIFINGLKKMGLEITITEEEKQILKNSKPDFIAFNYYSTMTVKMPTEESL
EEEEECCCCCCEEEECHHHCCCEEEEEHHHHHHHHCCCCCEEEEEEEEEEEEECCCHHHH
KNTKKDQQQGLSMPGFGESVKNDKLEKTQFGEIDPVGFRNTLREVYDRYQLPIMITENGI
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCC
GARDVLEEDGKIHDNYRIEYYEKHIQQMALAIADGVEMIGYMPSAIDLVSTHEGISKRYG
CHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
FVYVNRDEFDLKDMKRYKKDSFHYKELIKNNGENI
EEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKFPKDFLGASTSAYQFEGAIKQGGKVSSIMDRFDEQPSYPKGITGFKEASDHYNHKED
CCCCCCHHHCCCCCHHEECHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHH
VKLMSEMGFKSYRFSISPRIIKNKEGEINKEGIKFYNDLIDELFKHKIEPIVTMFHFDIP
HHHHHHCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DFIQEIGGVCTNEFTKQFEIYSEVLFKNFGSKIKYLTINELNMFALAGQIIGVVPSDQKI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHEEECCCCHHH
NSQLMHHLNVAQAKAIVLCRKICPSAKIGPAPNISTVYPDSNKPLDYVAKLNLDMVRNVY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHCCHHHHHHHH
LDIVCRGEYSPIFINGLKKMGLEITITEEEKQILKNSKPDFIAFNYYSTMTVKMPTEESL
EEEEECCCCCCEEEECHHHCCCEEEEEHHHHHHHHCCCCCEEEEEEEEEEEEECCCHHHH
KNTKKDQQQGLSMPGFGESVKNDKLEKTQFGEIDPVGFRNTLREVYDRYQLPIMITENGI
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCC
GARDVLEEDGKIHDNYRIEYYEKHIQQMALAIADGVEMIGYMPSAIDLVSTHEGISKRYG
CHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
FVYVNRDEFDLKDMKRYKKDSFHYKELIKNNGENI
EEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]