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The map label for this gene is rnpA

Identifier: 50086621

GI number: 50086621

Start: 3597604

End: 3597999

Strand: Reverse

Name: rnpA

Synonym: ACIAD3683

Alternate gene names: 50086621

Gene position: 3597999-3597604 (Counterclockwise)

Preceding gene: 50086622

Following gene: 50086620

Centisome position: 99.98

GC content: 41.16

Gene sequence:

>396_bases
GTGATGACACTTTATAGTTTCAGCACAGAAGTACGCTTACGCTGTGCTGCAGATTACCAAGGTGTGTTTGATGGTGCGCT
TTTTAAAGTGCATCAACCCCATTTCTTATTTCTTGCAAAACCCAGTGAACAGCTCCAGAGCCGTCTAGGGGTAATTGTTG
CCAAGAAAAAAGTTCGTCGTGCGCACGAAAGAAACAGAATAAAACGACTTGCTCGCGAAAGTTTTCGCTTGCATCAACAG
CAATTAGGTTTGCTGGATATTGTGGTGATGCCTAAGATAGGTATTGAAGCGGTATCTAATGCTGATTTGCATCAGCAGCT
TGAATTTGCTTGGCAAAAATTACAACGTCAAGCTAAAAAATATCAAAAAGTAGCTGTTTCTCCTTCTTTGCATTAG

Upstream 100 bases:

>100_bases
CTCGCATGGCTACTAAAGCTGGTCGTCAGGTTTTGGCTCGCCGTCGTGCTAAAGGTCGTCACAGCTTAACTGTTTAATTA
CGGTTAGTTGACACGATTGG

Downstream 100 bases:

>100_bases
AGATGAACCAATGGTACGCATACTTCATTGGTTGATTCGTTTCTATCAAATTGCGATTAGTCCAATGCTTGGACCTCGTT
GTCGATATATTCCAACCTGT

Product: RNase P C5 component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MMTLYSFSTEVRLRCAADYQGVFDGALFKVHQPHFLFLAKPSEQLQSRLGVIVAKKKVRRAHERNRIKRLARESFRLHQQ
QLGLLDIVVMPKIGIEAVSNADLHQQLEFAWQKLQRQAKKYQKVAVSPSLH

Sequences:

>Translated_131_residues
MMTLYSFSTEVRLRCAADYQGVFDGALFKVHQPHFLFLAKPSEQLQSRLGVIVAKKKVRRAHERNRIKRLARESFRLHQQ
QLGLLDIVVMPKIGIEAVSNADLHQQLEFAWQKLQRQAKKYQKVAVSPSLH
>Mature_131_residues
MMTLYSFSTEVRLRCAADYQGVFDGALFKVHQPHFLFLAKPSEQLQSRLGVIVAKKKVRRAHERNRIKRLARESFRLHQQ
QLGLLDIVVMPKIGIEAVSNADLHQQLEFAWQKLQRQAKKYQKVAVSPSLH

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=118, Percent_Identity=40.6779661016949, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_ACIAD (Q6F6K8)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_048131.1
- ProteinModelPortal:   Q6F6K8
- SMR:   Q6F6K8
- STRING:   Q6F6K8
- GeneID:   2879511
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3683
- NMPDR:   fig|62977.3.peg.3324
- eggNOG:   COG0594
- HOGENOM:   HBG728160
- OMA:   FTQLERQ
- PhylomeDB:   Q6F6K8
- ProtClustDB:   CLSK707971
- BioCyc:   ASP62977:ACIAD3683-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 15193; Mature: 15193

Theoretical pI: Translated: 11.04; Mature: 11.04

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLYSFSTEVRLRCAADYQGVFDGALFKVHQPHFLFLAKPSEQLQSRLGVIVAKKKVRR
CCEEECCCCCEEEEECCCCCCHHCCHHEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
AHERNRIKRLARESFRLHQQQLGLLDIVVMPKIGIEAVSNADLHQQLEFAWQKLQRQAKK
HHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
YQKVAVSPSLH
HHHHCCCCCCC
>Mature Secondary Structure
MMTLYSFSTEVRLRCAADYQGVFDGALFKVHQPHFLFLAKPSEQLQSRLGVIVAKKKVRR
CCEEECCCCCEEEEECCCCCCHHCCHHEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
AHERNRIKRLARESFRLHQQQLGLLDIVVMPKIGIEAVSNADLHQQLEFAWQKLQRQAKK
HHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
YQKVAVSPSLH
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA