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The map label for this gene is ndh [H]

Identifier: 50086577

GI number: 50086577

Start: 3544852

End: 3546183

Strand: Reverse

Name: ndh [H]

Synonym: ACIAD3633

Alternate gene names: 50086577

Gene position: 3546183-3544852 (Counterclockwise)

Preceding gene: 50086578

Following gene: 50086576

Centisome position: 98.54

GC content: 44.22

Gene sequence:

>1332_bases
TTGGAGAAACTTATGTCTACCGAAAAAACACAGACCTCAAATTTACACCGTATCGTGATCGTGGGCGGCGGTGCAGGAGG
GTTGGAACTCGCGACCCGTCTGGGTAATCAACTAGGCAAGCATCAACACGCAGAAATAATTTTGGTGGATGCCGCCTTGA
CGCACATCTGGAAGCCGTTACTGCATGAAGTTGCCGCTGGCACACTCAACTCTTATGAAGATGAACTGAATTATTTTGCG
CATGCCAGTCAGCATCATTTTGAGTTCTTTCTAGGACGACTGACTGATCTTGACCGCGCTAGCAAAAAAATTGTTTTAGG
CGCGCTGAAAGATGAGGATGGTAAAGAAGTTGCGCCAGAGCGTTGTATTGCCTATGACACACTGGTGCTGGCAATCGGGT
CTACATCCAATGATTTTGGAACACCAGGGGCTAAAGAACATTGTATTTTTCTGGACTCACGTCCGCAGGCCGACCGCTTC
CAACGTGAATTTTTGAGTTTATATCTTGAGGCTCAAGCCAGAAACCTGATTGAACCGCATGAAAATACGTTAAATATTGC
AATTATTGGGGCTGGTGCAACGGGTGTAGAGTTGGCTGCCGAGCTACATCATGCCGCCAATCAGTTTTCCAAGTATGGTT
TAAATAGTATTGATCCAAAAGACGTTAAAATTAGCCTGATTGAGGCGGCGCCCCGTATATTGCCTGCACTGTCTGAGCGT
GTGTCTGAGGGGGCAGAAAAAGAGCTGCAAAAAATAGGGGTGAATGTACTTAAAAATTGTCGTGTCACCCATATTGATGC
GCACAAGGTCTATTGCGAAGGTGATATTCAGATTCCTGCCACGCTAAAAGTCTGGTCGGCAGGGATCAAAGCTCCTGATT
TTTTAAAAAATATAGGTGGACTTGAAACCAATCGTATTAATCAACTGGTGGTAAAACCAAGTTTACAAACCACGTTGGAT
GACGACATTTTTGCGATGGGGGATTGTGCATGTTATATCCCGACAGGTGCTGAACGTCCTGTCCCACCACGTGCACAAGT
GGCCAATCAGGAAGCGATTTTTTTAGCTAAAGCATTGGCGCATCGCTTGCAAAATAAACCGCTTGGAACGTTTGAATTTA
AAGACAAAGGCTCGTTAGTGTCTTTAAGTAATCAGAGTACCGTAGGAAATATTCTAGGTAATATCAATGTTGAAGGTCTG
TTTGCACGCATGATGTATGTCTCTTTATATCGGTTTCATCAGGTCGCGTTGCACGGTGTATTTAAAACCAGCCTAATGAT
CATTAAAGATTTACTTTCTAAAGGCTCATCTCCGCAGTTAAAGTTACATTGA

Upstream 100 bases:

>100_bases
GTTGGTAAAAAGTATGTTTTTTACACATAACATTCGTGTTTATAATAACTTGCATTTTTCTTATGAATACTGATTAAAAA
AGTCGGTATTCATAAGAAAA

Downstream 100 bases:

>100_bases
TTTAGCCCAAAAACCGCATTTGTATTTGATTGATCAACCAGTATGGCAAACGCTGTACTGGTTTTTTTGTTCATTGCCGT
TTTAAAACGACCTCAATCAA

Product: NADH dehydrogenase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MEKLMSTEKTQTSNLHRIVIVGGGAGGLELATRLGNQLGKHQHAEIILVDAALTHIWKPLLHEVAAGTLNSYEDELNYFA
HASQHHFEFFLGRLTDLDRASKKIVLGALKDEDGKEVAPERCIAYDTLVLAIGSTSNDFGTPGAKEHCIFLDSRPQADRF
QREFLSLYLEAQARNLIEPHENTLNIAIIGAGATGVELAAELHHAANQFSKYGLNSIDPKDVKISLIEAAPRILPALSER
VSEGAEKELQKIGVNVLKNCRVTHIDAHKVYCEGDIQIPATLKVWSAGIKAPDFLKNIGGLETNRINQLVVKPSLQTTLD
DDIFAMGDCACYIPTGAERPVPPRAQVANQEAIFLAKALAHRLQNKPLGTFEFKDKGSLVSLSNQSTVGNILGNINVEGL
FARMMYVSLYRFHQVALHGVFKTSLMIIKDLLSKGSSPQLKLH

Sequences:

>Translated_443_residues
MEKLMSTEKTQTSNLHRIVIVGGGAGGLELATRLGNQLGKHQHAEIILVDAALTHIWKPLLHEVAAGTLNSYEDELNYFA
HASQHHFEFFLGRLTDLDRASKKIVLGALKDEDGKEVAPERCIAYDTLVLAIGSTSNDFGTPGAKEHCIFLDSRPQADRF
QREFLSLYLEAQARNLIEPHENTLNIAIIGAGATGVELAAELHHAANQFSKYGLNSIDPKDVKISLIEAAPRILPALSER
VSEGAEKELQKIGVNVLKNCRVTHIDAHKVYCEGDIQIPATLKVWSAGIKAPDFLKNIGGLETNRINQLVVKPSLQTTLD
DDIFAMGDCACYIPTGAERPVPPRAQVANQEAIFLAKALAHRLQNKPLGTFEFKDKGSLVSLSNQSTVGNILGNINVEGL
FARMMYVSLYRFHQVALHGVFKTSLMIIKDLLSKGSSPQLKLH
>Mature_443_residues
MEKLMSTEKTQTSNLHRIVIVGGGAGGLELATRLGNQLGKHQHAEIILVDAALTHIWKPLLHEVAAGTLNSYEDELNYFA
HASQHHFEFFLGRLTDLDRASKKIVLGALKDEDGKEVAPERCIAYDTLVLAIGSTSNDFGTPGAKEHCIFLDSRPQADRF
QREFLSLYLEAQARNLIEPHENTLNIAIIGAGATGVELAAELHHAANQFSKYGLNSIDPKDVKISLIEAAPRILPALSER
VSEGAEKELQKIGVNVLKNCRVTHIDAHKVYCEGDIQIPATLKVWSAGIKAPDFLKNIGGLETNRINQLVVKPSLQTTLD
DDIFAMGDCACYIPTGAERPVPPRAQVANQEAIFLAKALAHRLQNKPLGTFEFKDKGSLVSLSNQSTVGNILGNINVEGL
FARMMYVSLYRFHQVALHGVFKTSLMIIKDLLSKGSSPQLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=438, Percent_Identity=53.8812785388128, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6323794, Length=395, Percent_Identity=26.8354430379747, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320118, Length=433, Percent_Identity=24.0184757505774, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323515, Length=379, Percent_Identity=25.3298153034301, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48558; Mature: 48558

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLMSTEKTQTSNLHRIVIVGGGAGGLELATRLGNQLGKHQHAEIILVDAALTHIWKPL
CCCHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
LHEVAAGTLNSYEDELNYFAHASQHHFEFFLGRLTDLDRASKKIVLGALKDEDGKEVAPE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHH
RCIAYDTLVLAIGSTSNDFGTPGAKEHCIFLDSRPQADRFQREFLSLYLEAQARNLIEPH
HHHHHEEEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ENTLNIAIIGAGATGVELAAELHHAANQFSKYGLNSIDPKDVKISLIEAAPRILPALSER
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
VSEGAEKELQKIGVNVLKNCRVTHIDAHKVYCEGDIQIPATLKVWSAGIKAPDFLKNIGG
HHCCHHHHHHHHHHHHHHCCCEEEEECEEEEEECCEECCCCHHHHHCCCCCHHHHHHCCC
LETNRINQLVVKPSLQTTLDDDIFAMGDCACYIPTGAERPVPPRAQVANQEAIFLAKALA
CCCCCCCEEEECCCHHHCCCCCCEEECCEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHH
HRLQNKPLGTFEFKDKGSLVSLSNQSTVGNILGNINVEGLFARMMYVSLYRFHQVALHGV
HHHCCCCCCCEEECCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FKTSLMIIKDLLSKGSSPQLKLH
HHHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure
MEKLMSTEKTQTSNLHRIVIVGGGAGGLELATRLGNQLGKHQHAEIILVDAALTHIWKPL
CCCHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
LHEVAAGTLNSYEDELNYFAHASQHHFEFFLGRLTDLDRASKKIVLGALKDEDGKEVAPE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHH
RCIAYDTLVLAIGSTSNDFGTPGAKEHCIFLDSRPQADRFQREFLSLYLEAQARNLIEPH
HHHHHEEEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ENTLNIAIIGAGATGVELAAELHHAANQFSKYGLNSIDPKDVKISLIEAAPRILPALSER
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
VSEGAEKELQKIGVNVLKNCRVTHIDAHKVYCEGDIQIPATLKVWSAGIKAPDFLKNIGG
HHCCHHHHHHHHHHHHHHCCCEEEEECEEEEEECCEECCCCHHHHHCCCCCHHHHHHCCC
LETNRINQLVVKPSLQTTLDDDIFAMGDCACYIPTGAERPVPPRAQVANQEAIFLAKALA
CCCCCCCEEEECCCHHHCCCCCCEEECCEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHH
HRLQNKPLGTFEFKDKGSLVSLSNQSTVGNILGNINVEGLFARMMYVSLYRFHQVALHGV
HHHCCCCCCCEEECCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FKTSLMIIKDLLSKGSSPQLKLH
HHHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]