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The map label for this gene is mdtA [H]

Identifier: 50086571

GI number: 50086571

Start: 3536588

End: 3537697

Strand: Reverse

Name: mdtA [H]

Synonym: ACIAD3625

Alternate gene names: 50086571

Gene position: 3537697-3536588 (Counterclockwise)

Preceding gene: 50086576

Following gene: 50086570

Centisome position: 98.31

GC content: 47.03

Gene sequence:

>1110_bases
ATGAATCGAATATTCTTGATCCTGTCTGGTTGGGTCATGTTATGTATGCTGGGACTTTCGGGGTGCCATAAACAAACAGC
AGATCTAGAACAAGCACCTTTAGTTATGGTGGCACAGCCGCAGTCTTCACAGTCTCAAGCGCAAAGTTATGCTGGAAAAG
TGCAGGCTCGTCAGCAGACGGCATTGTCGTTTCGGGTTGGTGGACAAATTATAGAGCGTCTAGTTGAGGTAGGCGATCGT
GTACATGTGGGCCAAGTATTGGCCAAACTTGATGTACAGGATGCCCAGTTACAACTGAATGCAGCCAAGGCACAGTTGGA
TAATGCTCAGTCGGCTGCCAAGATTGCAGCGGATGAGTTACAGCGTTATCAGCAATTGTTGCCGATTAATGCAGTCAGTC
GTTCGCAATATGATGCCATCAAAAATCAGTATGATGCAGCGCAATCCAGTTTAAAACAGGCACGTTCCAATTATGATGTT
GCCAGTAATCAAACCAACTACAACCGCTTACTTGCCAATAAAAATGGAGTGATCACTGAACGTTTGATTGAGGTTGGACA
AGTCGTCGCAGCGGGACAAACAGCGTACCAACTCGCAATTGATGGTGATCGTGAAGTCGTCATTGGGCTGCCAGAACAAT
CAATTTCGTCTGTCAAAGTCGGTCAGCCTGCTTGGATGAGTCTATGGTCGCAACCTGAGCAAAAGTTTGCAGCCTACGTA
CGTGAAATTGCGCCTGCAGCCGATCAGTCGCGTACCTTTAGTGTCAAGGTTGCACTCAAGCAGGCACAGCCATCGATTCA
GATGGGACAAAGTGCACGGGTCTTTCTGAATGCTACACCACAGCAAAGCCAGTTAAGTATTCCCATGAGCAGTATCTCTG
CGACCAAGCAACAGCCGTATGTCTGGATTGTTAAGCCCAATAACACCATTCAAAAAGTCAATGTCCAGTTGGGTGCATAT
GGACGAGATGAAGTGACCATCCTTTCAGGATTAAAAAGTTCAGACTGGGTGGTCGTTGGCGGGGTGCATTTATTGCGTGA
TCAGCAAAAAATTAGACCCATCGACCGTGAAAACCGTGCAGTCAATATTCAGACAGGAGCCGTTCAATGA

Upstream 100 bases:

>100_bases
TAATTAATGTACCAATGGGTATATTAATTAAAAAACAAACACTCTAAGATAACCCTATATTGTGCCTTAAAAAATAAATT
TGAATAAGAGTGATGACATC

Downstream 100 bases:

>100_bases
ATTTTAATCTGTCTGAATGGGCTCTAAAAAATAAAGGCTTAATCTTATATCTGATGTTACTACTGGCGATTGTGGGCATT
TTTTCTTATTCCAAACTGTC

Product: RND efflux membrane fusion protein precursor

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNRIFLILSGWVMLCMLGLSGCHKQTADLEQAPLVMVAQPQSSQSQAQSYAGKVQARQQTALSFRVGGQIIERLVEVGDR
VHVGQVLAKLDVQDAQLQLNAAKAQLDNAQSAAKIAADELQRYQQLLPINAVSRSQYDAIKNQYDAAQSSLKQARSNYDV
ASNQTNYNRLLANKNGVITERLIEVGQVVAAGQTAYQLAIDGDREVVIGLPEQSISSVKVGQPAWMSLWSQPEQKFAAYV
REIAPAADQSRTFSVKVALKQAQPSIQMGQSARVFLNATPQQSQLSIPMSSISATKQQPYVWIVKPNNTIQKVNVQLGAY
GRDEVTILSGLKSSDWVVVGGVHLLRDQQKIRPIDRENRAVNIQTGAVQ

Sequences:

>Translated_369_residues
MNRIFLILSGWVMLCMLGLSGCHKQTADLEQAPLVMVAQPQSSQSQAQSYAGKVQARQQTALSFRVGGQIIERLVEVGDR
VHVGQVLAKLDVQDAQLQLNAAKAQLDNAQSAAKIAADELQRYQQLLPINAVSRSQYDAIKNQYDAAQSSLKQARSNYDV
ASNQTNYNRLLANKNGVITERLIEVGQVVAAGQTAYQLAIDGDREVVIGLPEQSISSVKVGQPAWMSLWSQPEQKFAAYV
REIAPAADQSRTFSVKVALKQAQPSIQMGQSARVFLNATPQQSQLSIPMSSISATKQQPYVWIVKPNNTIQKVNVQLGAY
GRDEVTILSGLKSSDWVVVGGVHLLRDQQKIRPIDRENRAVNIQTGAVQ
>Mature_369_residues
MNRIFLILSGWVMLCMLGLSGCHKQTADLEQAPLVMVAQPQSSQSQAQSYAGKVQARQQTALSFRVGGQIIERLVEVGDR
VHVGQVLAKLDVQDAQLQLNAAKAQLDNAQSAAKIAADELQRYQQLLPINAVSRSQYDAIKNQYDAAQSSLKQARSNYDV
ASNQTNYNRLLANKNGVITERLIEVGQVVAAGQTAYQLAIDGDREVVIGLPEQSISSVKVGQPAWMSLWSQPEQKFAAYV
REIAPAADQSRTFSVKVALKQAQPSIQMGQSARVFLNATPQQSQLSIPMSSISATKQQPYVWIVKPNNTIQKVNVQLGAY
GRDEVTILSGLKSSDWVVVGGVHLLRDQQKIRPIDRENRAVNIQTGAVQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=313, Percent_Identity=23.961661341853, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081796, Length=310, Percent_Identity=23.5483870967742, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789929, Length=362, Percent_Identity=21.8232044198895, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40418; Mature: 40418

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIFLILSGWVMLCMLGLSGCHKQTADLEQAPLVMVAQPQSSQSQAQSYAGKVQARQQT
CCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ALSFRVGGQIIERLVEVGDRVHVGQVLAKLDVQDAQLQLNAAKAQLDNAQSAAKIAADEL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHEEEHHHHHHHCCHHHHHHHHHHHH
QRYQQLLPINAVSRSQYDAIKNQYDAAQSSLKQARSNYDVASNQTNYNRLLANKNGVITE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHH
RLIEVGQVVAAGQTAYQLAIDGDREVVIGLPEQSISSVKVGQPAWMSLWSQPEQKFAAYV
HHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCEECCCCHHHHHHCCHHHHHHHHH
REIAPAADQSRTFSVKVALKQAQPSIQMGQSARVFLNATPQQSQLSIPMSSISATKQQPY
HHHCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCEECCCHHHHHCCCCCCE
VWIVKPNNTIQKVNVQLGAYGRDEVTILSGLKSSDWVVVGGVHLLRDQQKIRPIDRENRA
EEEECCCCCEEEEEEEECCCCCCCEEEEECCCCCCEEEECCHHHHCCHHHCCCCCCCCCE
VNIQTGAVQ
EEEECCCCC
>Mature Secondary Structure
MNRIFLILSGWVMLCMLGLSGCHKQTADLEQAPLVMVAQPQSSQSQAQSYAGKVQARQQT
CCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ALSFRVGGQIIERLVEVGDRVHVGQVLAKLDVQDAQLQLNAAKAQLDNAQSAAKIAADEL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHEEEHHHHHHHCCHHHHHHHHHHHH
QRYQQLLPINAVSRSQYDAIKNQYDAAQSSLKQARSNYDVASNQTNYNRLLANKNGVITE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHH
RLIEVGQVVAAGQTAYQLAIDGDREVVIGLPEQSISSVKVGQPAWMSLWSQPEQKFAAYV
HHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCEECCCCHHHHHHCCHHHHHHHHH
REIAPAADQSRTFSVKVALKQAQPSIQMGQSARVFLNATPQQSQLSIPMSSISATKQQPY
HHHCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCEECCCHHHHHCCCCCCE
VWIVKPNNTIQKVNVQLGAYGRDEVTILSGLKSSDWVVVGGVHLLRDQQKIRPIDRENRA
EEEECCCCCEEEEEEEECCCCCCCEEEEECCCCCCEEEECCHHHHCCHHHCCCCCCCCCE
VNIQTGAVQ
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA