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The map label for this gene is yhcK [H]

Identifier: 50086486

GI number: 50086486

Start: 3457081

End: 3458262

Strand: Direct

Name: yhcK [H]

Synonym: ACIAD3531

Alternate gene names: 50086486

Gene position: 3457081-3458262 (Clockwise)

Preceding gene: 50086485

Following gene: 50086491

Centisome position: 96.07

GC content: 39.68

Gene sequence:

>1182_bases
ATGACGAAAACAAACTCTAGACTCTGGTCTTTTATTTTTAGCCTGTATATGAAGAATCCTATTATTAATTGGACGGTTCT
TGAGAAATGCAAACTCATCATCCTGCTGTCATCTGGCATGATTTTGAGCTGGATTGTCTGGAAGCTTTTTGTACTGTTAC
ATCCAGAGCTATGGAAATACGTAAATATTAGATTAATCGAAATCGACATGTGGGTATGCAGCCTCACATTGACTGTTTTA
ATTTTCTTGATGTATCTGTGTCATTATCATGCACATAGAATCTGGATCCAGAAAGTTATTCCTATTGTCACTATTTATCT
GTTTGCCCTGGTCCTATACCATGGGAGTTATATGACGGGTTCTTTAAGCCCAGCAACGGCAGTAGGTTATATCAGTACAG
CGGTCATTGGTTTAATTTTATTTGACCGCTGGCTCATTTATATTACCTTGATTCCAGCGACCTTATTACTCCTTATAGCT
GGCTATCTAAGCCTAAAGCAATACATTCCCTATGCACCAGTTTTTAATATCGCTGCCCTAAAACCATCGCCTGCACAACA
CAATTTTTGGGTGGGTAGTATGGTGTTTTTTTCGGTGCCTATCCTGATTGGATTTTTTGGTTTATTTGAGATTTTACTTT
CACAATGGCGCGAGCGTGAAGATGAAATTAAGCGTCTCAGTCAACTAGATTTTCTGACCAATCTTTTAAATCGTCGTAGT
ATTCATCAGGTTTTAGATCATTTTCATCAAACCAGAGCAGAAAAAAATTACGCGGTGATTTTATTGGATCTTGATCACTT
TAAGCAGATTAACGATCAGTATGGTCATCATGTAGGAGATCAGGTTCTCATTGCTATCAGTGAATGTCTGACACAACATG
TTCATCCTCTCAACAACATTGGACGTTTTGGCGGAGAAGAATTTATTATTCTGATTCCAGAGACCTCATTGTCGGCTGCA
CGAGAAATCGCAGAGTGTTGTCGACTGGCTATTCAACAGCTCAACATTGCCACTACGCAAGATAATATTCAGCTCAGCGC
AAGCTTTGGGGTGGCTATATCCTCACTTCAGTATGAAGCCAGTCAGATTCTGACCCAAGCCGATCAAGCACTTTATTTTG
CCAAAGCCTGTGGTCGAAACCAGGTGAGGACTTTTCCAGAATATATCCAGCAGAATTTCTAA

Upstream 100 bases:

>100_bases
AGCGACATTTAAAAAAAAATAAGAAGAAGAAATATCAGATAGATCATAATAAATGCTATCTTAAACGCTGAAATCTAATA
CAAGTCATGGATAATTTCGC

Downstream 100 bases:

>100_bases
GCCATACAATCAATTAACGCTGTATATTTTTAAATGCAGCTAGCTGTTGAAGTAATTCATTTTTACTAAACGCACCTGTG
AGGCGTAAGTTGCGAATTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTKTNSRLWSFIFSLYMKNPIINWTVLEKCKLIILLSSGMILSWIVWKLFVLLHPELWKYVNIRLIEIDMWVCSLTLTVL
IFLMYLCHYHAHRIWIQKVIPIVTIYLFALVLYHGSYMTGSLSPATAVGYISTAVIGLILFDRWLIYITLIPATLLLLIA
GYLSLKQYIPYAPVFNIAALKPSPAQHNFWVGSMVFFSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRS
IHQVLDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAA
REIAECCRLAIQQLNIATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQVRTFPEYIQQNF

Sequences:

>Translated_393_residues
MTKTNSRLWSFIFSLYMKNPIINWTVLEKCKLIILLSSGMILSWIVWKLFVLLHPELWKYVNIRLIEIDMWVCSLTLTVL
IFLMYLCHYHAHRIWIQKVIPIVTIYLFALVLYHGSYMTGSLSPATAVGYISTAVIGLILFDRWLIYITLIPATLLLLIA
GYLSLKQYIPYAPVFNIAALKPSPAQHNFWVGSMVFFSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRS
IHQVLDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAA
REIAECCRLAIQQLNIATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQVRTFPEYIQQNF
>Mature_392_residues
TKTNSRLWSFIFSLYMKNPIINWTVLEKCKLIILLSSGMILSWIVWKLFVLLHPELWKYVNIRLIEIDMWVCSLTLTVLI
FLMYLCHYHAHRIWIQKVIPIVTIYLFALVLYHGSYMTGSLSPATAVGYISTAVIGLILFDRWLIYITLIPATLLLLIAG
YLSLKQYIPYAPVFNIAALKPSPAQHNFWVGSMVFFSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRSI
HQVLDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAR
EIAECCRLAIQQLNIATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQVRTFPEYIQQNF

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=38.3647798742138, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=31.9767441860465, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=35.031847133758, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=32.0987654320988, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=33.5403726708075, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786584, Length=196, Percent_Identity=32.6530612244898, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787802, Length=192, Percent_Identity=29.1666666666667, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787541, Length=187, Percent_Identity=34.2245989304813, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787816, Length=156, Percent_Identity=32.0512820512821, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788381, Length=159, Percent_Identity=30.8176100628931, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1787056, Length=156, Percent_Identity=32.0512820512821, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081977, Length=243, Percent_Identity=28.8065843621399, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788956, Length=150, Percent_Identity=30, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 45257; Mature: 45126

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTNSRLWSFIFSLYMKNPIINWTVLEKCKLIILLSSGMILSWIVWKLFVLLHPELWKY
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEECCCHHHHHHHHHHHHHHCHHHHHH
VNIRLIEIDMWVCSLTLTVLIFLMYLCHYHAHRIWIQKVIPIVTIYLFALVLYHGSYMTG
HCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SLSPATAVGYISTAVIGLILFDRWLIYITLIPATLLLLIAGYLSLKQYIPYAPVFNIAAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
KPSPAQHNFWVGSMVFFSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHQVLDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNI
HHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
GRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIATTQDNIQLSASFGVAISSLQYEA
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEEHHHHHHHHHHHH
SQILTQADQALYFAKACGRNQVRTFPEYIQQNF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TKTNSRLWSFIFSLYMKNPIINWTVLEKCKLIILLSSGMILSWIVWKLFVLLHPELWKY
CCCHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEECCCHHHHHHHHHHHHHHCHHHHHH
VNIRLIEIDMWVCSLTLTVLIFLMYLCHYHAHRIWIQKVIPIVTIYLFALVLYHGSYMTG
HCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SLSPATAVGYISTAVIGLILFDRWLIYITLIPATLLLLIAGYLSLKQYIPYAPVFNIAAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
KPSPAQHNFWVGSMVFFSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHQVLDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNI
HHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
GRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIATTQDNIQLSASFGVAISSLQYEA
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEEHHHHHHHHHHHH
SQILTQADQALYFAKACGRNQVRTFPEYIQQNF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]