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The map label for this gene is murG

Identifier: 50086474

GI number: 50086474

Start: 3444924

End: 3446021

Strand: Reverse

Name: murG

Synonym: ACIAD3517

Alternate gene names: 50086474

Gene position: 3446021-3444924 (Counterclockwise)

Preceding gene: 50086475

Following gene: 50086473

Centisome position: 95.76

GC content: 45.45

Gene sequence:

>1098_bases
GTGACTGATCCATCACAAGTTAAACCTAAACATGTCATGATGATGGCTGCTGGCACGGGCGGTCATGTGTTTCCTGCATT
AGCTGTGGCAAAACAACTCCAACAACACGGCTGTCAGGTATCATGGCTTGCAACGCCTGCGGGTATGGAAAACCGTTTAC
TGAAAGATCAGAATATTCCGATTTATCAGATTGATATTCAAGGTGTGCGTGGTAATGGGGCAGTACGTAAACTTCTGGCT
CCCTTTAAAATTTTAAAAGCCACTTACAGTGCTATGCGTTATATGAAACAGCTCAAAGTTGATGCTGTAGCAGGTTTTGG
TGGTTATGTGGCGGGTCCTGGTGGTTTGGCGGCACGCATTTTGGGGATTCCAATTCTGATTCATGAACAGAACGCTGTTG
CGGGATTCACCAATACTCAGCTCGCTCGTGTGGCCTCAAAAGTATGTGAAGCATTTCCAAATACATTTCCCGCAAGTGCC
AAACGAGTGACTACAGGTAATCCTGTACGAAAAGAAATTACCGCAATTTTAAGTCCAAAATGGCGTTATGATAGCCGTGA
GCAAGCGGGACAACCTTTAAATATTCTGATTGTGGGAGGGTCGTTAGGCGCGCAGGCACTTAATGAACGGTTACCCGATG
CATTGAAAAATCTCAATTTACCCCTCAATGTGTTTCATCAGTGTGGACAGAAACAGTTTGAAGAAACCCGAGTGCGTTAC
ACAAATGCTCCTGCGAATATGAGCGTACAGGTAATGCCATTTATTGAAGATATGGCACAAGCCTATCGTGATGCAGATCT
GATTATTTGTCGCGCAGGTGCGCTAACCGTCACTGAAGTTGCGACTGCTGGTGTTGCGGCAGTATTTGTGCCTTTACCGA
TTGCGGTGGACGATCATCAGACTGCAAATGCCAGATTTCTGGCAGATGTCGGTGCAGCCAAGATTTGCCAGCAATCGACC
ATGACGCCAGAAAACTTGGATGCATTACTTAAACCGTTAATGAATCGTCAGTTACTTTCAGAAATGGCTGTAAAAGCCCG
TCAACATGCACAACCCAATGCTACCCAACACGTGGTAGACCTTATTCAAACTTTGTAA

Upstream 100 bases:

>100_bases
ACACGTGAAATAAGCTTTTCGTTATGTATGCTTTAGGATTAGAATAATCTGCTAAATAAATACCCGTTATTTCCTTTGTT
TTTGAGCTGAAGAATATACC

Downstream 100 bases:

>100_bases
GTTAGAGTGCTCTATGTCACCAACAACCCCTGCCGATCAAGCAAAAAAACTCATTAAAGTTCCTGAAATGCGCCGTATCA
AACACATTTATTTTGTGGGA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTDPSQVKPKHVMMMAAGTGGHVFPALAVAKQLQQHGCQVSWLATPAGMENRLLKDQNIPIYQIDIQGVRGNGAVRKLLA
PFKILKATYSAMRYMKQLKVDAVAGFGGYVAGPGGLAARILGIPILIHEQNAVAGFTNTQLARVASKVCEAFPNTFPASA
KRVTTGNPVRKEITAILSPKWRYDSREQAGQPLNILIVGGSLGAQALNERLPDALKNLNLPLNVFHQCGQKQFEETRVRY
TNAPANMSVQVMPFIEDMAQAYRDADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANARFLADVGAAKICQQST
MTPENLDALLKPLMNRQLLSEMAVKARQHAQPNATQHVVDLIQTL

Sequences:

>Translated_365_residues
MTDPSQVKPKHVMMMAAGTGGHVFPALAVAKQLQQHGCQVSWLATPAGMENRLLKDQNIPIYQIDIQGVRGNGAVRKLLA
PFKILKATYSAMRYMKQLKVDAVAGFGGYVAGPGGLAARILGIPILIHEQNAVAGFTNTQLARVASKVCEAFPNTFPASA
KRVTTGNPVRKEITAILSPKWRYDSREQAGQPLNILIVGGSLGAQALNERLPDALKNLNLPLNVFHQCGQKQFEETRVRY
TNAPANMSVQVMPFIEDMAQAYRDADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANARFLADVGAAKICQQST
MTPENLDALLKPLMNRQLLSEMAVKARQHAQPNATQHVVDLIQTL
>Mature_364_residues
TDPSQVKPKHVMMMAAGTGGHVFPALAVAKQLQQHGCQVSWLATPAGMENRLLKDQNIPIYQIDIQGVRGNGAVRKLLAP
FKILKATYSAMRYMKQLKVDAVAGFGGYVAGPGGLAARILGIPILIHEQNAVAGFTNTQLARVASKVCEAFPNTFPASAK
RVTTGNPVRKEITAILSPKWRYDSREQAGQPLNILIVGGSLGAQALNERLPDALKNLNLPLNVFHQCGQKQFEETRVRYT
NAPANMSVQVMPFIEDMAQAYRDADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANARFLADVGAAKICQQSTM
TPENLDALLKPLMNRQLLSEMAVKARQHAQPNATQHVVDLIQTL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=355, Percent_Identity=43.3802816901408, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ACIAD (Q6F703)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047984.1
- ProteinModelPortal:   Q6F703
- SMR:   Q6F703
- STRING:   Q6F703
- GeneID:   2880559
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3517
- NMPDR:   fig|62977.3.peg.3177
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q6F703
- ProtClustDB:   PRK00726
- BioCyc:   ASP62977:ACIAD3517-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39444; Mature: 39313

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPSQVKPKHVMMMAAGTGGHVFPALAVAKQLQQHGCQVSWLATPAGMENRLLKDQNIP
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCC
IYQIDIQGVRGNGAVRKLLAPFKILKATYSAMRYMKQLKVDAVAGFGGYVAGPGGLAARI
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LGIPILIHEQNAVAGFTNTQLARVASKVCEAFPNTFPASAKRVTTGNPVRKEITAILSPK
HCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
WRYDSREQAGQPLNILIVGGSLGAQALNERLPDALKNLNLPLNVFHQCGQKQFEETRVRY
CCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEE
TNAPANMSVQVMPFIEDMAQAYRDADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQ
ECCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHEEEEECCEEECCCC
TANARFLADVGAAKICQQSTMTPENLDALLKPLMNRQLLSEMAVKARQHAQPNATQHVVD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIQTL
HHHHC
>Mature Secondary Structure 
TDPSQVKPKHVMMMAAGTGGHVFPALAVAKQLQQHGCQVSWLATPAGMENRLLKDQNIP
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCC
IYQIDIQGVRGNGAVRKLLAPFKILKATYSAMRYMKQLKVDAVAGFGGYVAGPGGLAARI
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LGIPILIHEQNAVAGFTNTQLARVASKVCEAFPNTFPASAKRVTTGNPVRKEITAILSPK
HCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
WRYDSREQAGQPLNILIVGGSLGAQALNERLPDALKNLNLPLNVFHQCGQKQFEETRVRY
CCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEE
TNAPANMSVQVMPFIEDMAQAYRDADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQ
ECCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHEEEEECCEEECCCC
TANARFLADVGAAKICQQSTMTPENLDALLKPLMNRQLLSEMAVKARQHAQPNATQHVVD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIQTL
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA