Click here to switch to the map view.

The map label for this gene is ftsA [H]

Identifier: 50086470

GI number: 50086470

Start: 3440298

End: 3441560

Strand: Reverse

Name: ftsA [H]

Synonym: ACIAD3512

Alternate gene names: 50086470

Gene position: 3441560-3440298 (Counterclockwise)

Preceding gene: 50086471

Following gene: 50086469

Centisome position: 95.64

GC content: 45.05

Gene sequence:

>1263_bases
ATGAGTGAAGCTGTTCCCTCGGTTGTTGCGATTGACATTGGGACACATAAAGTTTCAGTTTTGATTGGTAAAGTTCACGC
ACCGGATAACATTCAGGTCATCGGGATGGCCACTGCACGTAACCGTGGCATGAATAAAGGCAAAATAGTTAGTCTCGATA
AAGTCATCTCCGCAATTAAAAATGCCGTTGCTGAAGCGGAAAACATGGCTGAATGCCGTGTTCACACAGCATGGGTGTCG
ATTCCAACAACAGAATTACAAAGTTTTTATGCTTCGGGTCGTATCCCTATTGCGAAAGCTGATCATACTATTACCACGAA
TGAGGTCGTGCGCGCGTTAGAACTTGCAAAAGCAAGCCATGTCACGCCAGATTATTACTTGGCCAGTGCTGTACCACTTG
GTTTTGAACTGGATGATTCATCAGAATGGGTTCAGAATCCGATCAATATGTCGGCACATAGTATGACTGGACATTATCAG
TTGATGATGATGCCGATCAGTATCATGCAAAATCTGGATCGGGCCATGAAAGGTGCCAGTATCGGTGTCGAAAAAATGGT
GGTGTCCTGTCTTGCAACAGCCGAAGCCAGCTTGCTTAAAGATGAAAAAGAGTACGGTGTCTGTTTGTTGGATATTGGGG
CAGGCACAACCAATATTGCGGTGTATCTGGATGGTCGTTTGGCGCTTGCGAGAACGTTGCAGCGTGGTGGCGAAAATGTA
ACGCGCGATATTGCGGCCGTTTTACAAACGACGACAGAAGAAGCTGAACGCATCAAAATTCTACATGGTTGCGTCGATTT
AAGCGCCATTAAGCCTGATCAAATGATTCAAGTGCAAGCCATTGATGGCCCACAGACCATTAGTCGTATTGAACTTGCTG
AAATCATTATTGCGCGTTATGAAGAAATTCTTGGACAAGTACGTGATGAACTTGAACGAAGCGGTGCCATTCATGGTTTA
TATCATGGTGTGGTACTAACAGGTGACGCTTGCCAAATTGAGGGAATGATTAGTTTGGCACGTCGTATACTGGGTGTTTC
TGCACATCTGGGGAATCCGCCATTACAGGTTTATGCTGATGATCAGCATCAAGCTTCGATTCGACGTTCTATGTATGCCA
CAGCAGCGGGTTTATTGATGTTCAGTCAAAGCGAGCTGCAAGATACGGTCGAAGATTCCGAAGAAGCGTCACAACGTTCG
TTATGGAATCGTGTTGCAAATGGCTGGAATACCTTGAATACCAAGCTAAAAGCCATCTTTTAA

Upstream 100 bases:

>100_bases
ACAAATGTTGCATCTGGAATGACAGCAAAGCCATAATGTTTGGCTTTTAAATAACAGGCATTTTTTGCCATATTAGACAA
CGAACAAATGGTAGTGAGTA

Downstream 100 bases:

>100_bases
GGTGTATGTGTTTTTAGGGAATATTGTTGGGATGTTGTAATAGTAAATTGTCATACTTGACAAGCTAAGTATTGAGCAGC
ATCCTAAAATCTATTGTTTA

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSEAVPSVVAIDIGTHKVSVLIGKVHAPDNIQVIGMATARNRGMNKGKIVSLDKVISAIKNAVAEAENMAECRVHTAWVS
IPTTELQSFYASGRIPIAKADHTITTNEVVRALELAKASHVTPDYYLASAVPLGFELDDSSEWVQNPINMSAHSMTGHYQ
LMMMPISIMQNLDRAMKGASIGVEKMVVSCLATAEASLLKDEKEYGVCLLDIGAGTTNIAVYLDGRLALARTLQRGGENV
TRDIAAVLQTTTEEAERIKILHGCVDLSAIKPDQMIQVQAIDGPQTISRIELAEIIIARYEEILGQVRDELERSGAIHGL
YHGVVLTGDACQIEGMISLARRILGVSAHLGNPPLQVYADDQHQASIRRSMYATAAGLLMFSQSELQDTVEDSEEASQRS
LWNRVANGWNTLNTKLKAIF

Sequences:

>Translated_420_residues
MSEAVPSVVAIDIGTHKVSVLIGKVHAPDNIQVIGMATARNRGMNKGKIVSLDKVISAIKNAVAEAENMAECRVHTAWVS
IPTTELQSFYASGRIPIAKADHTITTNEVVRALELAKASHVTPDYYLASAVPLGFELDDSSEWVQNPINMSAHSMTGHYQ
LMMMPISIMQNLDRAMKGASIGVEKMVVSCLATAEASLLKDEKEYGVCLLDIGAGTTNIAVYLDGRLALARTLQRGGENV
TRDIAAVLQTTTEEAERIKILHGCVDLSAIKPDQMIQVQAIDGPQTISRIELAEIIIARYEEILGQVRDELERSGAIHGL
YHGVVLTGDACQIEGMISLARRILGVSAHLGNPPLQVYADDQHQASIRRSMYATAAGLLMFSQSELQDTVEDSEEASQRS
LWNRVANGWNTLNTKLKAIF
>Mature_419_residues
SEAVPSVVAIDIGTHKVSVLIGKVHAPDNIQVIGMATARNRGMNKGKIVSLDKVISAIKNAVAEAENMAECRVHTAWVSI
PTTELQSFYASGRIPIAKADHTITTNEVVRALELAKASHVTPDYYLASAVPLGFELDDSSEWVQNPINMSAHSMTGHYQL
MMMPISIMQNLDRAMKGASIGVEKMVVSCLATAEASLLKDEKEYGVCLLDIGAGTTNIAVYLDGRLALARTLQRGGENVT
RDIAAVLQTTTEEAERIKILHGCVDLSAIKPDQMIQVQAIDGPQTISRIELAEIIIARYEEILGQVRDELERSGAIHGLY
HGVVLTGDACQIEGMISLARRILGVSAHLGNPPLQVYADDQHQASIRRSMYATAAGLLMFSQSELQDTVEDSEEASQRSL
WNRVANGWNTLNTKLKAIF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=417, Percent_Identity=29.9760191846523, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45613; Mature: 45482

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAVPSVVAIDIGTHKVSVLIGKVHAPDNIQVIGMATARNRGMNKGKIVSLDKVISAIK
CCCCCCCEEEEECCCEEEEEEEEEECCCCCEEEEEEEEHHCCCCCCCCEEEHHHHHHHHH
NAVAEAENMAECRVHTAWVSIPTTELQSFYASGRIPIAKADHTITTNEVVRALELAKASH
HHHHHHHHHHHHEEEEEEEECCHHHHHHHHHCCCCEEECCCCEECHHHHHHHHHHHHHCC
VTPDYYLASAVPLGFELDDSSEWVQNPINMSAHSMTGHYQLMMMPISIMQNLDRAMKGAS
CCCCHHHHHCCCCCEEECCCHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCC
IGVEKMVVSCLATAEASLLKDEKEYGVCLLDIGAGTTNIAVYLDGRLALARTLQRGGENV
CCHHHHHHHHHHHHHHHHHCCCHHCCEEEEEECCCCCEEEEEECCHHHHHHHHHHCCCHH
TRDIAAVLQTTTEEAERIKILHGCVDLSAIKPDQMIQVQAIDGPQTISRIELAEIIIARY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
EEILGQVRDELERSGAIHGLYHGVVLTGDACQIEGMISLARRILGVSAHLGNPPLQVYAD
HHHHHHHHHHHHHCCCCEEEEECEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DQHQASIRRSMYATAAGLLMFSQSELQDTVEDSEEASQRSLWNRVANGWNTLNTKLKAIF
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEECC
>Mature Secondary Structure 
SEAVPSVVAIDIGTHKVSVLIGKVHAPDNIQVIGMATARNRGMNKGKIVSLDKVISAIK
CCCCCCEEEEECCCEEEEEEEEEECCCCCEEEEEEEEHHCCCCCCCCEEEHHHHHHHHH
NAVAEAENMAECRVHTAWVSIPTTELQSFYASGRIPIAKADHTITTNEVVRALELAKASH
HHHHHHHHHHHHEEEEEEEECCHHHHHHHHHCCCCEEECCCCEECHHHHHHHHHHHHHCC
VTPDYYLASAVPLGFELDDSSEWVQNPINMSAHSMTGHYQLMMMPISIMQNLDRAMKGAS
CCCCHHHHHCCCCCEEECCCHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCC
IGVEKMVVSCLATAEASLLKDEKEYGVCLLDIGAGTTNIAVYLDGRLALARTLQRGGENV
CCHHHHHHHHHHHHHHHHHCCCHHCCEEEEEECCCCCEEEEEECCHHHHHHHHHHCCCHH
TRDIAAVLQTTTEEAERIKILHGCVDLSAIKPDQMIQVQAIDGPQTISRIELAEIIIARY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
EEILGQVRDELERSGAIHGLYHGVVLTGDACQIEGMISLARRILGVSAHLGNPPLQVYAD
HHHHHHHHHHHHHCCCCEEEEECEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DQHQASIRRSMYATAAGLLMFSQSELQDTVEDSEEASQRSLWNRVANGWNTLNTKLKAIF
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]