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The map label for this gene is mocR [H]

Identifier: 50086411

GI number: 50086411

Start: 3367748

End: 3369247

Strand: Direct

Name: mocR [H]

Synonym: ACIAD3447

Alternate gene names: 50086411

Gene position: 3367748-3369247 (Clockwise)

Preceding gene: 50086404

Following gene: 50086416

Centisome position: 93.58

GC content: 46.4

Gene sequence:

>1500_bases
TTGCGTAGTTTGCTGGGCGATCATTTACTACAACGTCTCCAACAAGACGTGGAAGGGAAGCTTCATCAACGTTTATTTCG
CTGTTTAAGAGGCGCAATTATCGAAGGTGTGATTCAGCCCAAAACACGTTTACCTGCTTCACGAGATCTGGCCAAAGAGA
TTCATGTATCACGAAATACTGTACTGTCAGCCTATGAGCAGCTTCAGGCCGAAGGCTATCTGGAAGCCCGAACAGGTCAT
GGCACATGGGTTGCCGAACAACTGCCCGAGGCTTTTTTAAATACGCCTCATGGCAAGCAACTGGTTGGATTACGCAATCC
ACCACGTTCATATACGCTGTCACAACGTGGCTCACAGCTTATGGGTTATGCTGCGGCTTCTCCACATCAATGGGGGCCAT
TTGTTCCAGGTGCACCCGATGTCACCGAGTTTCCACATCATATTTTTAGCCGCATTCAGGCACGTTTAAGCCGTGAACCA
GAAATTAGCCATCTGATTTATAGCAATGCAGGTGGCTGCGCCGAGTTACGTAGTGCACTGGCAGATTATTTACGTGTAGC
ACGTTCGGTACAATGTGACCCAGATCAGATTTTGATCACCGAAGGTGTACATCAGGCGATTGATCTGGTTTCGCGTGCAT
TATGCGATATTGGCGATCAGGTCTGGATTGAAGATCCTGCCTACTGGGGCATGCGAAACACCCTTCGGATTAATGGACTA
CAGATTCAGCCGATGCCAGTAGATGCAGATGGTATTATTCCCCAGCAGTATCCAGAACATCCGCCAAAGTTAATCTTTGT
CACGCCTTCACATCAGTATCCACTGGGTTCACATTTGAGTCTGGAACGCCGTAAATCGTTGCTTAATATTGCCAAGCGAC
ATGGTAGCTGGATTGTGGAAGATGATTATGACAGTGAGTTTCGCTTTTCTGGTCAGCCTTATCCTTCTTTGCAAGGTCTG
GAAACCGATGCACCTGTGATCTATATGGGAACATTTAGTAAAACCATTTATCCTGCGTTACGTATTGGTTATCTGGTGGT
TCCCAAGCCATTGTTTTCACCCTTAAGAATTTTAGCTGCCGAGCTATATCGTGGCGGACATTTGCTTGAGCAAAAAGCAC
TGGCCGAGTTTATTCGTGAAGGACACTACCAAGCCCATATTCGGCGTATGCGCCTGTTGTACGGTAAACGCCGCGCATAT
CTGGTAGATTTAATTCATCGTTATCTTGGACCCGAATTTGTACACCAATACAATGATGACTCTGGATTACATCTGGTCTT
GAAATTGCCTGATTTTTGCGACGATGTCGCCATTGCCACCTCGGCACTCGAACGTGGTATTAAAGTTCGTCCACTCTCTC
AATATTATATGCATGCACATGCCAATGCAGAGCGCGGTCTACTGATGGGCTTTGCCTGTGTCACTGAAAAAGATATGGTG
ATGGCATTTGGTATTTTGTTGCAATGTTTACGAGAAGCCAACGTCCAAACACGTAGTTAA

Upstream 100 bases:

>100_bases
ATAAATTTCAGAATGCTTTACAATAGCTGTCTATGTCTGTAATTTCGCGCGTCTTGCGTCAACTGACGAGAGCCACTTTT
CAACTCCAGGAGAGAGCCAA

Downstream 100 bases:

>100_bases
AGCCTGTGTGCCAGATTTTTTCCCATAAAAAAAGAACCTCTTATGAGGTTCTTTTTTAAATTCTAATGCTTAAGTCATCG
ATTTCTTGCTTTGCTCTAGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MRSLLGDHLLQRLQQDVEGKLHQRLFRCLRGAIIEGVIQPKTRLPASRDLAKEIHVSRNTVLSAYEQLQAEGYLEARTGH
GTWVAEQLPEAFLNTPHGKQLVGLRNPPRSYTLSQRGSQLMGYAAASPHQWGPFVPGAPDVTEFPHHIFSRIQARLSREP
EISHLIYSNAGGCAELRSALADYLRVARSVQCDPDQILITEGVHQAIDLVSRALCDIGDQVWIEDPAYWGMRNTLRINGL
QIQPMPVDADGIIPQQYPEHPPKLIFVTPSHQYPLGSHLSLERRKSLLNIAKRHGSWIVEDDYDSEFRFSGQPYPSLQGL
ETDAPVIYMGTFSKTIYPALRIGYLVVPKPLFSPLRILAAELYRGGHLLEQKALAEFIREGHYQAHIRRMRLLYGKRRAY
LVDLIHRYLGPEFVHQYNDDSGLHLVLKLPDFCDDVAIATSALERGIKVRPLSQYYMHAHANAERGLLMGFACVTEKDMV
MAFGILLQCLREANVQTRS

Sequences:

>Translated_499_residues
MRSLLGDHLLQRLQQDVEGKLHQRLFRCLRGAIIEGVIQPKTRLPASRDLAKEIHVSRNTVLSAYEQLQAEGYLEARTGH
GTWVAEQLPEAFLNTPHGKQLVGLRNPPRSYTLSQRGSQLMGYAAASPHQWGPFVPGAPDVTEFPHHIFSRIQARLSREP
EISHLIYSNAGGCAELRSALADYLRVARSVQCDPDQILITEGVHQAIDLVSRALCDIGDQVWIEDPAYWGMRNTLRINGL
QIQPMPVDADGIIPQQYPEHPPKLIFVTPSHQYPLGSHLSLERRKSLLNIAKRHGSWIVEDDYDSEFRFSGQPYPSLQGL
ETDAPVIYMGTFSKTIYPALRIGYLVVPKPLFSPLRILAAELYRGGHLLEQKALAEFIREGHYQAHIRRMRLLYGKRRAY
LVDLIHRYLGPEFVHQYNDDSGLHLVLKLPDFCDDVAIATSALERGIKVRPLSQYYMHAHANAERGLLMGFACVTEKDMV
MAFGILLQCLREANVQTRS
>Mature_499_residues
MRSLLGDHLLQRLQQDVEGKLHQRLFRCLRGAIIEGVIQPKTRLPASRDLAKEIHVSRNTVLSAYEQLQAEGYLEARTGH
GTWVAEQLPEAFLNTPHGKQLVGLRNPPRSYTLSQRGSQLMGYAAASPHQWGPFVPGAPDVTEFPHHIFSRIQARLSREP
EISHLIYSNAGGCAELRSALADYLRVARSVQCDPDQILITEGVHQAIDLVSRALCDIGDQVWIEDPAYWGMRNTLRINGL
QIQPMPVDADGIIPQQYPEHPPKLIFVTPSHQYPLGSHLSLERRKSLLNIAKRHGSWIVEDDYDSEFRFSGQPYPSLQGL
ETDAPVIYMGTFSKTIYPALRIGYLVVPKPLFSPLRILAAELYRGGHLLEQKALAEFIREGHYQAHIRRMRLLYGKRRAY
LVDLIHRYLGPEFVHQYNDDSGLHLVLKLPDFCDDVAIATSALERGIKVRPLSQYYMHAHANAERGLLMGFACVTEKDMV
MAFGILLQCLREANVQTRS

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=356, Percent_Identity=26.4044943820225, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI33469970, Length=356, Percent_Identity=26.4044943820225, Blast_Score=109, Evalue=6e-24,
Organism=Escherichia coli, GI1787710, Length=442, Percent_Identity=29.185520361991, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1790797, Length=437, Percent_Identity=28.604118993135, Blast_Score=132, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321236, Length=343, Percent_Identity=23.6151603498542, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56438; Mature: 56438

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLLGDHLLQRLQQDVEGKLHQRLFRCLRGAIIEGVIQPKTRLPASRDLAKEIHVSRNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHH
VLSAYEQLQAEGYLEARTGHGTWVAEQLPEAFLNTPHGKQLVGLRNPPRSYTLSQRGSQL
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHCCCHH
MGYAAASPHQWGPFVPGAPDVTEFPHHIFSRIQARLSREPEISHLIYSNAGGCAELRSAL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCHHHHHHHH
ADYLRVARSVQCDPDQILITEGVHQAIDLVSRALCDIGDQVWIEDPAYWGMRNTLRINGL
HHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCE
QIQPMPVDADGIIPQQYPEHPPKLIFVTPSHQYPLGSHLSLERRKSLLNIAKRHGSWIVE
EEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
DDYDSEFRFSGQPYPSLQGLETDAPVIYMGTFSKTIYPALRIGYLVVPKPLFSPLRILAA
CCCCCCEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCEEEECCHHHHHHHHHHH
ELYRGGHLLEQKALAEFIREGHYQAHIRRMRLLYGKRRAYLVDLIHRYLGPEFVHQYNDD
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC
SGLHLVLKLPDFCDDVAIATSALERGIKVRPLSQYYMHAHANAERGLLMGFACVTEKDMV
CCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHCCHHHH
MAFGILLQCLREANVQTRS
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRSLLGDHLLQRLQQDVEGKLHQRLFRCLRGAIIEGVIQPKTRLPASRDLAKEIHVSRNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHH
VLSAYEQLQAEGYLEARTGHGTWVAEQLPEAFLNTPHGKQLVGLRNPPRSYTLSQRGSQL
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHCCCHH
MGYAAASPHQWGPFVPGAPDVTEFPHHIFSRIQARLSREPEISHLIYSNAGGCAELRSAL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCHHHHHHHH
ADYLRVARSVQCDPDQILITEGVHQAIDLVSRALCDIGDQVWIEDPAYWGMRNTLRINGL
HHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCE
QIQPMPVDADGIIPQQYPEHPPKLIFVTPSHQYPLGSHLSLERRKSLLNIAKRHGSWIVE
EEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
DDYDSEFRFSGQPYPSLQGLETDAPVIYMGTFSKTIYPALRIGYLVVPKPLFSPLRILAA
CCCCCCEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCEEEECCHHHHHHHHHHH
ELYRGGHLLEQKALAEFIREGHYQAHIRRMRLLYGKRRAYLVDLIHRYLGPEFVHQYNDD
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC
SGLHLVLKLPDFCDDVAIATSALERGIKVRPLSQYYMHAHANAERGLLMGFACVTEKDMV
CCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHCCHHHH
MAFGILLQCLREANVQTRS
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]