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The map label for this gene is mdtA [H]

Identifier: 50086392

GI number: 50086392

Start: 3338035

End: 3339333

Strand: Reverse

Name: mdtA [H]

Synonym: ACIAD3424

Alternate gene names: 50086392

Gene position: 3339333-3338035 (Counterclockwise)

Preceding gene: 50086393

Following gene: 50086391

Centisome position: 92.79

GC content: 44.11

Gene sequence:

>1299_bases
ATGAATGGAAATTCACTACCAGAAAATAGCGAAAAAAATGACCGAAAAAAGAAGGTGTTTGTAAGTTATATCATCTTGTT
TATTATATTATTTTTGGTTGGATGGGGAATCTGGTTTTTAACCCATCAACCTATTGCATCTGCCCGAAGTGGTGCACATG
GGAAAGGTGGACAAAAAGCAGGGTTGGGTCTGAATGGCGCACCCATCGCGGTTGGTGTGAGTAAAGTTGTACAACAAGAC
GTGCAACAAACGATTCAGGCACTGGGAACCGTCACTTCTAGCAATACCGTTGTAGTCCATCCATTGATCAATGGCACCTT
GATGCAAATCTATTTTAAAGAAGGTGGATTGGTTCATAAGGGTCAGTTGTTGGCACTTATTGATGATCGGGCACCCAAAG
CAGCTTTGCTACAAGCACAAGGGCAGTTACTCAAAGATCAGGCTTTACTCACCAATGCTCAACTGGATTTGCAGCGCTAT
GCACAATTGTGGCAGCAAGATTCAATTGCAAAGCAGCAATACGACACTCAGGCCTCGTTGGTTAAACAATATCAAGGTGT
TCTTAAAACAGATCAGGCTGCTGTAGATAATGCAAAACTGCAATTAAGCTACACCCGTGTTGTTTCGCCAGTCGATGGAC
GAATTGGTTTAAGACAGATTGATGTTGGCAATATGGTCAACTCTTCAGATACCAATGGCATTGCCAATATTACCCAGCTC
AAAAATATTTCAGTTGTGTTTGCTGTGCCAGAGCAATATCTCACCCAATTAATGCAGATTACAGATCATCCAGACCAGCC
GATTGAGGTAGCGGCATGGGATCGTCAAAATACGCAAAAACTTGCCGATGGCAAGCTCGTGGCGCTGGATAATCAGGTGA
ATGTCACCACGGGAACCATCAACATTAAAGCCAGTTTTGACAATCATAATCAGCATTTATTTCCGAATCAGTTTGTCAAT
GTAAGAATGAGTTTGGGCAATATTCCAAATGCGCTAATTGTGCCAACAGTCGCATTACAACTGGGTGCCCATGGCTCTTT
TGTCTATAAAGTTAATTCAGATCAGAAGGTGAGTGCAGTGAATGTTCAAACAGGCACGGTGGTAGAGGACAATACAGTCA
TTACGGGTGGAGCACTAAATGCCAATGATACTGTGGTAACGGATGGGGTGGATAAGCTTAAGGACGGCGCAAAAATTACG
CTTGCAAGTGCAGCACACCACGGCTTAGGGCAGCATCGCGCTCAAAATCATGCGTCAAACTCGGCGGTTACTCAGCCTTC
TGCGCCCACTGCGCAGTAA

Upstream 100 bases:

>100_bases
TATACAAAAGATTTAGCGGGCTGAATGCTCGTGTTTAAGCTTAGATTAACACTATAAGAATATTTATATGACAACTTGAT
CAGTCGTACAGATCCTTCTT

Downstream 100 bases:

>100_bases
GGAGTGTTGATGAATCCGTCCCGTTTGTTTATCCAGCGACCAGTGGCGACCACACTGGTGATGATCGCAATTTTTTTGTG
TGGGCTGGTGTCCTGGAAAT

Product: membrane protein inolved in drug resistance

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MNGNSLPENSEKNDRKKKVFVSYIILFIILFLVGWGIWFLTHQPIASARSGAHGKGGQKAGLGLNGAPIAVGVSKVVQQD
VQQTIQALGTVTSSNTVVVHPLINGTLMQIYFKEGGLVHKGQLLALIDDRAPKAALLQAQGQLLKDQALLTNAQLDLQRY
AQLWQQDSIAKQQYDTQASLVKQYQGVLKTDQAAVDNAKLQLSYTRVVSPVDGRIGLRQIDVGNMVNSSDTNGIANITQL
KNISVVFAVPEQYLTQLMQITDHPDQPIEVAAWDRQNTQKLADGKLVALDNQVNVTTGTINIKASFDNHNQHLFPNQFVN
VRMSLGNIPNALIVPTVALQLGAHGSFVYKVNSDQKVSAVNVQTGTVVEDNTVITGGALNANDTVVTDGVDKLKDGAKIT
LASAAHHGLGQHRAQNHASNSAVTQPSAPTAQ

Sequences:

>Translated_432_residues
MNGNSLPENSEKNDRKKKVFVSYIILFIILFLVGWGIWFLTHQPIASARSGAHGKGGQKAGLGLNGAPIAVGVSKVVQQD
VQQTIQALGTVTSSNTVVVHPLINGTLMQIYFKEGGLVHKGQLLALIDDRAPKAALLQAQGQLLKDQALLTNAQLDLQRY
AQLWQQDSIAKQQYDTQASLVKQYQGVLKTDQAAVDNAKLQLSYTRVVSPVDGRIGLRQIDVGNMVNSSDTNGIANITQL
KNISVVFAVPEQYLTQLMQITDHPDQPIEVAAWDRQNTQKLADGKLVALDNQVNVTTGTINIKASFDNHNQHLFPNQFVN
VRMSLGNIPNALIVPTVALQLGAHGSFVYKVNSDQKVSAVNVQTGTVVEDNTVITGGALNANDTVVTDGVDKLKDGAKIT
LASAAHHGLGQHRAQNHASNSAVTQPSAPTAQ
>Mature_432_residues
MNGNSLPENSEKNDRKKKVFVSYIILFIILFLVGWGIWFLTHQPIASARSGAHGKGGQKAGLGLNGAPIAVGVSKVVQQD
VQQTIQALGTVTSSNTVVVHPLINGTLMQIYFKEGGLVHKGQLLALIDDRAPKAALLQAQGQLLKDQALLTNAQLDLQRY
AQLWQQDSIAKQQYDTQASLVKQYQGVLKTDQAAVDNAKLQLSYTRVVSPVDGRIGLRQIDVGNMVNSSDTNGIANITQL
KNISVVFAVPEQYLTQLMQITDHPDQPIEVAAWDRQNTQKLADGKLVALDNQVNVTTGTINIKASFDNHNQHLFPNQFVN
VRMSLGNIPNALIVPTVALQLGAHGSFVYKVNSDQKVSAVNVQTGTVVEDNTVITGGALNANDTVVTDGVDKLKDGAKIT
LASAAHHGLGQHRAQNHASNSAVTQPSAPTAQ

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=391, Percent_Identity=42.7109974424552, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1786668, Length=358, Percent_Identity=29.8882681564246, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789665, Length=356, Percent_Identity=27.5280898876405, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789929, Length=324, Percent_Identity=27.1604938271605, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46441; Mature: 46441

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGNSLPENSEKNDRKKKVFVSYIILFIILFLVGWGIWFLTHQPIASARSGAHGKGGQKA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
GLGLNGAPIAVGVSKVVQQDVQQTIQALGTVTSSNTVVVHPLINGTLMQIYFKEGGLVHK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCEEEC
GQLLALIDDRAPKAALLQAQGQLLKDQALLTNAQLDLQRYAQLWQQDSIAKQQYDTQASL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKQYQGVLKTDQAAVDNAKLQLSYTRVVSPVDGRIGLRQIDVGNMVNSSDTNGIANITQL
HHHHHHHHHCCHHHCCCCEEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEHHHH
KNISVVFAVPEQYLTQLMQITDHPDQPIEVAAWDRQNTQKLADGKLVALDNQVNVTTGTI
CCEEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCEEEEECCEEEEEEEEE
NIKASFDNHNQHLFPNQFVNVRMSLGNIPNALIVPTVALQLGAHGSFVYKVNSDQKVSAV
EEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHEECCCCEEEEEECCCCEEEEE
NVQTGTVVEDNTVITGGALNANDTVVTDGVDKLKDGAKITLASAAHHGLGQHRAQNHASN
EEECCCEEECCEEEECCCCCCCCEEEECCHHHHCCCCEEEEEHHHHCCCHHHHHHHCCCC
SAVTQPSAPTAQ
CCCCCCCCCCCC
>Mature Secondary Structure
MNGNSLPENSEKNDRKKKVFVSYIILFIILFLVGWGIWFLTHQPIASARSGAHGKGGQKA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
GLGLNGAPIAVGVSKVVQQDVQQTIQALGTVTSSNTVVVHPLINGTLMQIYFKEGGLVHK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCEEEC
GQLLALIDDRAPKAALLQAQGQLLKDQALLTNAQLDLQRYAQLWQQDSIAKQQYDTQASL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKQYQGVLKTDQAAVDNAKLQLSYTRVVSPVDGRIGLRQIDVGNMVNSSDTNGIANITQL
HHHHHHHHHCCHHHCCCCEEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEHHHH
KNISVVFAVPEQYLTQLMQITDHPDQPIEVAAWDRQNTQKLADGKLVALDNQVNVTTGTI
CCEEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCEEEEECCEEEEEEEEE
NIKASFDNHNQHLFPNQFVNVRMSLGNIPNALIVPTVALQLGAHGSFVYKVNSDQKVSAV
EEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHEECCCCEEEEEECCCCEEEEE
NVQTGTVVEDNTVITGGALNANDTVVTDGVDKLKDGAKITLASAAHHGLGQHRAQNHASN
EEECCCEEECCEEEECCCCCCCCEEEECCHHHHCCCCEEEEEHHHHCCCHHHHHHHCCCC
SAVTQPSAPTAQ
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA