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The map label for this gene is thrB [H]

Identifier: 50086377

GI number: 50086377

Start: 3319628

End: 3320626

Strand: Reverse

Name: thrB [H]

Synonym: ACIAD3403

Alternate gene names: 50086377

Gene position: 3320626-3319628 (Counterclockwise)

Preceding gene: 50086379

Following gene: 50086376

Centisome position: 92.27

GC content: 42.34

Gene sequence:

>999_bases
CTGCTTGGGTATTCTATCAAACTTATATTTGTTTCACGCAGGTTTTATATGTCGGTTTATACCCCGTTGAGTTTACAGGA
AGTTCAAGCATTTGCATTGCCTTATGGATTAGAGGTGATTGACTTGATTCCAATTCAGGGAGGTATTGAAAACACCAATT
ACTTTTTGGTCGCAAACAATCAGCAACAGTATGTTTTAACGGTTTTTGAAGAGCTAGATGAGCAGGGAGCAAGTGAGTTG
CCGCCTGTATTACAGCATTTGGGGCAGGCGCATGTGCCTGTTGCTGTGCCTTTAAATTATGAAGGCAAGTTTATCCATCG
TATTGCGCAAAAACCTGCACAAATTGCACCACGTATTGCGGGTGAACATCCGATTCCATCGAATATTGCACAAGTCAAAA
GTATTGCCGCTGCACAGGCAAGTTTACATCTGGCTTTGCAGAATTATTCTTTAGCGCGCTCAAACAGCCGTAACCATCAG
TTCTGGACAGCCGTAGGTGAAAGCTTAAAACCCGTGATGTCTACAGAAGATCTGAATCTTTTAAATCAGGTGTATGTACA
GTTTAATCAGCTTCGTGAGCAACATCCAGATTTGCCGTGTGGCTGGATTCATTCGGATATGTTCCGCGACAATACCTTGT
TTGTGGGGGATGAACTGGAAGGTATCTTGGATTTTTCTGAATTAAATCAGGATGATTTTTTATTTGATATTGCGATTAGC
ATCAATGATTTTTGTACAGAATATCCAGAAGCATATTTAGACCATGACAAGCTACAGGCATTTGTAGATGCTTACCAATC
TGTACGTAGCTTGACGCAGGATGAACACACATGTTTGCCCATTTATCTGGCGATGGCAGCCTGTCGTTTCTGGCTGATGC
GTTTACAGGTAGCACAGCGTAACGCGCAGGAAGGCCGTATAGGTGATGATATTATGCAGAAAAATCCACTCGAAATGCGC
AATATGCTGGTAGACCGTTTACAGGCAATGGCGAAATAA

Upstream 100 bases:

>100_bases
ACATCAAGGCAGGGAATAATACGTTTTGCAAGCATTGTGGCATCCAACAGTATGAGTCTAAATAAATAAATTTTCCGAGA
TTGCAGAGAATCTTGGTAAA

Downstream 100 bases:

>100_bases
GGATATACGGATATGCGAGATCAGGGACGTTTGGTCGAGTGGTTTGATGACAAGGGCTATGGCTTTATTCAGCCCAATGA
TTCTCAAAAGGGCCGTGTAT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLGYSIKLIFVSRRFYMSVYTPLSLQEVQAFALPYGLEVIDLIPIQGGIENTNYFLVANNQQQYVLTVFEELDEQGASEL
PPVLQHLGQAHVPVAVPLNYEGKFIHRIAQKPAQIAPRIAGEHPIPSNIAQVKSIAAAQASLHLALQNYSLARSNSRNHQ
FWTAVGESLKPVMSTEDLNLLNQVYVQFNQLREQHPDLPCGWIHSDMFRDNTLFVGDELEGILDFSELNQDDFLFDIAIS
INDFCTEYPEAYLDHDKLQAFVDAYQSVRSLTQDEHTCLPIYLAMAACRFWLMRLQVAQRNAQEGRIGDDIMQKNPLEMR
NMLVDRLQAMAK

Sequences:

>Translated_332_residues
MLGYSIKLIFVSRRFYMSVYTPLSLQEVQAFALPYGLEVIDLIPIQGGIENTNYFLVANNQQQYVLTVFEELDEQGASEL
PPVLQHLGQAHVPVAVPLNYEGKFIHRIAQKPAQIAPRIAGEHPIPSNIAQVKSIAAAQASLHLALQNYSLARSNSRNHQ
FWTAVGESLKPVMSTEDLNLLNQVYVQFNQLREQHPDLPCGWIHSDMFRDNTLFVGDELEGILDFSELNQDDFLFDIAIS
INDFCTEYPEAYLDHDKLQAFVDAYQSVRSLTQDEHTCLPIYLAMAACRFWLMRLQVAQRNAQEGRIGDDIMQKNPLEMR
NMLVDRLQAMAK
>Mature_332_residues
MLGYSIKLIFVSRRFYMSVYTPLSLQEVQAFALPYGLEVIDLIPIQGGIENTNYFLVANNQQQYVLTVFEELDEQGASEL
PPVLQHLGQAHVPVAVPLNYEGKFIHRIAQKPAQIAPRIAGEHPIPSNIAQVKSIAAAQASLHLALQNYSLARSNSRNHQ
FWTAVGESLKPVMSTEDLNLLNQVYVQFNQLREQHPDLPCGWIHSDMFRDNTLFVGDELEGILDFSELNQDDFLFDIAIS
INDFCTEYPEAYLDHDKLQAFVDAYQSVRSLTQDEHTCLPIYLAMAACRFWLMRLQVAQRNAQEGRIGDDIMQKNPLEMR
NMLVDRLQAMAK

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 37788; Mature: 37788

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGYSIKLIFVSRRFYMSVYTPLSLQEVQAFALPYGLEVIDLIPIQGGIENTNYFLVANN
CCCEEEEEEEEEHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEECC
QQQYVLTVFEELDEQGASELPPVLQHLGQAHVPVAVPLNYEGKFIHRIAQKPAQIAPRIA
CCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHCCHHHHCCHHC
GEHPIPSNIAQVKSIAAAQASLHLALQNYSLARSNSRNHQFWTAVGESLKPVMSTEDLNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
LNQVYVQFNQLREQHPDLPCGWIHSDMFRDNTLFVGDELEGILDFSELNQDDFLFDIAIS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCEEEEEEEC
INDFCTEYPEAYLDHDKLQAFVDAYQSVRSLTQDEHTCLPIYLAMAACRFWLMRLQVAQR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
NAQEGRIGDDIMQKNPLEMRNMLVDRLQAMAK
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLGYSIKLIFVSRRFYMSVYTPLSLQEVQAFALPYGLEVIDLIPIQGGIENTNYFLVANN
CCCEEEEEEEEEHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEECC
QQQYVLTVFEELDEQGASELPPVLQHLGQAHVPVAVPLNYEGKFIHRIAQKPAQIAPRIA
CCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHCCHHHHCCHHC
GEHPIPSNIAQVKSIAAAQASLHLALQNYSLARSNSRNHQFWTAVGESLKPVMSTEDLNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
LNQVYVQFNQLREQHPDLPCGWIHSDMFRDNTLFVGDELEGILDFSELNQDDFLFDIAIS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCEEEEEEEC
INDFCTEYPEAYLDHDKLQAFVDAYQSVRSLTQDEHTCLPIYLAMAACRFWLMRLQVAQR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
NAQEGRIGDDIMQKNPLEMRNMLVDRLQAMAK
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]