Click here to switch to the map view.

The map label for this gene is ldcC [H]

Identifier: 50086322

GI number: 50086322

Start: 3244453

End: 3247242

Strand: Direct

Name: ldcC [H]

Synonym: ACIAD3341

Alternate gene names: 50086322

Gene position: 3244453-3247242 (Clockwise)

Preceding gene: 50086321

Following gene: 50086323

Centisome position: 90.16

GC content: 44.01

Gene sequence:

>2790_bases
ATGACGAATACAAATTCATTAAGCCAGCATCGTAGCGTATGGGAGATACGTTCTGATAGCTGGATTAATCTCGTAGAAGA
TATTGGGTATCTGGCAGATCTTCAGATTAATAACCAAGATCGTGCCAAAGTTTTAACTCGTTTACGGCTCACTCTGGATT
TTTTAATTCCAATTGAAAGTTATTGGGCATTTCCAAGCAAGCGAGTTTTTGCTGAACTCTGTCAGTATATTGAACGTGAA
GATTTTACTACCGCTCGACAGCTTGCACGCCGTATTCATCGTGCCTTGTCTGCGGGGACTTATCGTCACGATAACAAAGT
GCTCCAAAGTGAACGTGAATTACCCTCTCACATTGAAACCACAAGTGAGCAACAGGCACGTCTATCTCAGCCTTATTTTG
AAGTGCTCATCGTGGATGAAATGTCTCCAGCAGAAGAGGATGCACTGCGTCGTCGAGTGATTAGCAAGCGCTGTTCTGAC
GATCCATTTATTTTTGATATTGTGGTTGTTCCGAGCTTTGAAGATGCCCTGATTGCATCCCTAATTAATTTCAACTTACA
AGCTGTGGTGATTCGGCACGGCTTTCCAGCACGATCGGTCAATCATGTTGATATGCTGGAACGTTTATTTATAGATGTCG
ATCAGGATATTGAATCCCTTCCAGAAATGGAGCGTGGAACACTATTAGGCCGCCATATCGCGAAGTTACGTCCAGAACTG
GATCTCTATTTAGTGACCGATGCAGGTGTGGAAAATATTGCTTCTCATGCTGGCAGTGAAATCTTTAAACGCATTTTCTT
TGGCGAAGAAGACCATATCGAGCTCTACAATGCGATTATGAAAGGTGTGGGTGAGCGTTACCGTACACCATTCTTTAATG
CATTACGCGATTATTCCAAACAACCAACAGGTATGTTCCATGCACTGCCACTGGCACGTGGTAAAGCCATTCTTAATAGC
AACTGGATTGGTGATCTGGCACAGTTTTATGGCATGAATTTATTTATGGCCGAAACATCAGCCACTTCAGGCGGTCTGGA
TTCATTACTGGAACCTGTTGGCCCATTAAAACATGCGCAGGAATATGCAGCCCGTGCATTTGGTGCCAAACGGACTTTCT
TTGCAACCAATGGAACCTCCACCTGTAACAAGATTGTGGTGCAATCTCTGGTACGTGAAGGTGATATTGTACTGGTAGAT
CGCAACTGTCATAAATCACATCATTATGGTTTGGTGCTTACAGGCGCCAGTGCCGCCTATCTCGATTCGTATCCACTCAA
TGAATACTCAATGTATGGGGCGGTGCCAATTTGGCACATTAAACAAACTTTATTGAGCTTTAAACGAGCAGGTACGCTTG
ATCGCGTTAAACTGGTTCTACTCACCAATTGTACCTTTGATGGTGTTGTCTATGACGTAGAACGGGTGATGATGGAATGC
CTGGCCATTAAACCTGATCTGATTTTTTTATGGGATGAAGCATGGTTTGCTTTTGCAAGTTGTCATCCCATTTATCGCCA
ACGCACAGCCATGGCCAATGCCGCTAAGCTGGCTGAACGTTTTAAAACGCCTGAATATGCCCGAGAATATGCCGAGTGGA
AAGACAGTATTGACTGGGAAGATGATCAACAGCTCATCAACACTCGTCTCATGCCAGACCCTGCTTTGGCACGTGTTCGC
GTTTATTCAACGCATTCGACACACAAGACCTTAACTGCACTGCGTCAGGGTTCCATGATTCATATCTGGGATCAGGATTT
TAAAGAAAAGAGCGAAGAAGCTTTTATTGAAGCTTACATGACCCATACTTCAACTTCGGCCAATTATCAGATTCTGGCAT
CGCTGGATGTAGGACGGCGTCAGGTTGAAATGGAAGGTTATCAACTGGTACAGCGACAGCTTGAACTTGCGATGAGCCTG
CGCGAACAGGTCATGCATCACCCCTTACTCAAGCGTCATTTCCACTTCTTGCGCGTTGGCAATATCATTCCAACTGCTTA
CCGTGAATCTGGAGTCAATAGCTATTTTGATGAAGGTAAAGGCTGGGCAAATTTAGAGAAAGCGTGGAGCATGGATGAGT
TTGTCATGGATCCTACCCGCGCAACGCTGATGATTGGTATGGTCGGGATGGATGGAGATACCTTCAAAAATACCGAACTC
ATGAATAAATACGGGATTCAAATCAATAAGACCTCTCGTAATACTGTTCTGTTTATTATCAATATTGGAACCACACGTTC
TGCAATTGCTTATCTGATTGAAGTGCTGGTCAAGATTGCACGTGATGTAGATCGTCGTGTAGCTGACATGAGCTCAGCCG
AGCGTCGCATTCACTTAAAACGTGTTAACTCTCTCACTCAAGAGCAACCACCATTACCTGATTTCTCTGCTTTCCATCGT
GCATTTCGGGGTCAAAGTCTAAACCCAGCCATTCAAACCCGTGACGGTAATATTCGTCAGGCATTTTTTCTGTCCTATGA
AGATTCGAGCTGTGAATATATTGATATGCAGGAAGCAGCCGTAGCTATTGCATCAGGTCGTGAACTGGTTTCAGCCCTGT
TTGTAATTCCATATCCGCCTGGCTTTCCAATTTTAGTACCTGGGCAGGTCATCAGCTCTGAAATTTTAAAATTCATGGCA
GCACTGGATGTGAAAGAAATTCATGGTTTCCGCCCTGAACTCGGATTTCGTGTCTTTACACAAGAAACGCTTGATCGAGT
TCTACACGCAAAAGAATCTTTTGAATCGATTATGCAATATCAGCAAATCAATAACTTACGTGCTGGATAG

Upstream 100 bases:

>100_bases
ATCTGGATAGTTTAGGTCCATTGGTCAAACCAGACGACTAAATTGATTAAAAACTAAAACGTAAAAGATAAAGAAAGATT
GATAACAAAGATATAAGCTT

Downstream 100 bases:

>100_bases
ATCATTAAAAAACTGAACCCGAAACAGATGGAACACAATATATGAGTATCCAGTATCCACCCTCTATTTGTGCATTCATC
CGACACTATTGGCAAAGTCT

Product: arginine/lysine/ornithine decarboxylase

Products: NA

Alternate protein names: LDC [H]

Number of amino acids: Translated: 929; Mature: 928

Protein sequence:

>929_residues
MTNTNSLSQHRSVWEIRSDSWINLVEDIGYLADLQINNQDRAKVLTRLRLTLDFLIPIESYWAFPSKRVFAELCQYIERE
DFTTARQLARRIHRALSAGTYRHDNKVLQSERELPSHIETTSEQQARLSQPYFEVLIVDEMSPAEEDALRRRVISKRCSD
DPFIFDIVVVPSFEDALIASLINFNLQAVVIRHGFPARSVNHVDMLERLFIDVDQDIESLPEMERGTLLGRHIAKLRPEL
DLYLVTDAGVENIASHAGSEIFKRIFFGEEDHIELYNAIMKGVGERYRTPFFNALRDYSKQPTGMFHALPLARGKAILNS
NWIGDLAQFYGMNLFMAETSATSGGLDSLLEPVGPLKHAQEYAARAFGAKRTFFATNGTSTCNKIVVQSLVREGDIVLVD
RNCHKSHHYGLVLTGASAAYLDSYPLNEYSMYGAVPIWHIKQTLLSFKRAGTLDRVKLVLLTNCTFDGVVYDVERVMMEC
LAIKPDLIFLWDEAWFAFASCHPIYRQRTAMANAAKLAERFKTPEYAREYAEWKDSIDWEDDQQLINTRLMPDPALARVR
VYSTHSTHKTLTALRQGSMIHIWDQDFKEKSEEAFIEAYMTHTSTSANYQILASLDVGRRQVEMEGYQLVQRQLELAMSL
REQVMHHPLLKRHFHFLRVGNIIPTAYRESGVNSYFDEGKGWANLEKAWSMDEFVMDPTRATLMIGMVGMDGDTFKNTEL
MNKYGIQINKTSRNTVLFIINIGTTRSAIAYLIEVLVKIARDVDRRVADMSSAERRIHLKRVNSLTQEQPPLPDFSAFHR
AFRGQSLNPAIQTRDGNIRQAFFLSYEDSSCEYIDMQEAAVAIASGRELVSALFVIPYPPGFPILVPGQVISSEILKFMA
ALDVKEIHGFRPELGFRVFTQETLDRVLHAKESFESIMQYQQINNLRAG

Sequences:

>Translated_929_residues
MTNTNSLSQHRSVWEIRSDSWINLVEDIGYLADLQINNQDRAKVLTRLRLTLDFLIPIESYWAFPSKRVFAELCQYIERE
DFTTARQLARRIHRALSAGTYRHDNKVLQSERELPSHIETTSEQQARLSQPYFEVLIVDEMSPAEEDALRRRVISKRCSD
DPFIFDIVVVPSFEDALIASLINFNLQAVVIRHGFPARSVNHVDMLERLFIDVDQDIESLPEMERGTLLGRHIAKLRPEL
DLYLVTDAGVENIASHAGSEIFKRIFFGEEDHIELYNAIMKGVGERYRTPFFNALRDYSKQPTGMFHALPLARGKAILNS
NWIGDLAQFYGMNLFMAETSATSGGLDSLLEPVGPLKHAQEYAARAFGAKRTFFATNGTSTCNKIVVQSLVREGDIVLVD
RNCHKSHHYGLVLTGASAAYLDSYPLNEYSMYGAVPIWHIKQTLLSFKRAGTLDRVKLVLLTNCTFDGVVYDVERVMMEC
LAIKPDLIFLWDEAWFAFASCHPIYRQRTAMANAAKLAERFKTPEYAREYAEWKDSIDWEDDQQLINTRLMPDPALARVR
VYSTHSTHKTLTALRQGSMIHIWDQDFKEKSEEAFIEAYMTHTSTSANYQILASLDVGRRQVEMEGYQLVQRQLELAMSL
REQVMHHPLLKRHFHFLRVGNIIPTAYRESGVNSYFDEGKGWANLEKAWSMDEFVMDPTRATLMIGMVGMDGDTFKNTEL
MNKYGIQINKTSRNTVLFIINIGTTRSAIAYLIEVLVKIARDVDRRVADMSSAERRIHLKRVNSLTQEQPPLPDFSAFHR
AFRGQSLNPAIQTRDGNIRQAFFLSYEDSSCEYIDMQEAAVAIASGRELVSALFVIPYPPGFPILVPGQVISSEILKFMA
ALDVKEIHGFRPELGFRVFTQETLDRVLHAKESFESIMQYQQINNLRAG
>Mature_928_residues
TNTNSLSQHRSVWEIRSDSWINLVEDIGYLADLQINNQDRAKVLTRLRLTLDFLIPIESYWAFPSKRVFAELCQYIERED
FTTARQLARRIHRALSAGTYRHDNKVLQSERELPSHIETTSEQQARLSQPYFEVLIVDEMSPAEEDALRRRVISKRCSDD
PFIFDIVVVPSFEDALIASLINFNLQAVVIRHGFPARSVNHVDMLERLFIDVDQDIESLPEMERGTLLGRHIAKLRPELD
LYLVTDAGVENIASHAGSEIFKRIFFGEEDHIELYNAIMKGVGERYRTPFFNALRDYSKQPTGMFHALPLARGKAILNSN
WIGDLAQFYGMNLFMAETSATSGGLDSLLEPVGPLKHAQEYAARAFGAKRTFFATNGTSTCNKIVVQSLVREGDIVLVDR
NCHKSHHYGLVLTGASAAYLDSYPLNEYSMYGAVPIWHIKQTLLSFKRAGTLDRVKLVLLTNCTFDGVVYDVERVMMECL
AIKPDLIFLWDEAWFAFASCHPIYRQRTAMANAAKLAERFKTPEYAREYAEWKDSIDWEDDQQLINTRLMPDPALARVRV
YSTHSTHKTLTALRQGSMIHIWDQDFKEKSEEAFIEAYMTHTSTSANYQILASLDVGRRQVEMEGYQLVQRQLELAMSLR
EQVMHHPLLKRHFHFLRVGNIIPTAYRESGVNSYFDEGKGWANLEKAWSMDEFVMDPTRATLMIGMVGMDGDTFKNTELM
NKYGIQINKTSRNTVLFIINIGTTRSAIAYLIEVLVKIARDVDRRVADMSSAERRIHLKRVNSLTQEQPPLPDFSAFHRA
FRGQSLNPAIQTRDGNIRQAFFLSYEDSSCEYIDMQEAAVAIASGRELVSALFVIPYPPGFPILVPGQVISSEILKFMAA
LDVKEIHGFRPELGFRVFTQETLDRVLHAKESFESIMQYQQINNLRAG

Specific function: LDC is constitutively but weakly expressed under various conditions [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=633, Percent_Identity=26.3823064770932, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI221142684, Length=638, Percent_Identity=26.3322884012539, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1790573, Length=629, Percent_Identity=26.0731319554849, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI87082193, Length=665, Percent_Identity=25.5639097744361, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1786909, Length=676, Percent_Identity=23.5207100591716, Blast_Score=150, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.18 [H]

Molecular weight: Translated: 106194; Mature: 106062

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTNSLSQHRSVWEIRSDSWINLVEDIGYLADLQINNQDRAKVLTRLRLTLDFLIPIES
CCCCCCHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHEEHHH
YWAFPSKRVFAELCQYIEREDFTTARQLARRIHRALSAGTYRHDNKVLQSERELPSHIET
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHC
TSEQQARLSQPYFEVLIVDEMSPAEEDALRRRVISKRCSDDPFIFDIVVVPSFEDALIAS
CCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHH
LINFNLQAVVIRHGFPARSVNHVDMLERLFIDVDQDIESLPEMERGTLLGRHIAKLRPEL
HHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCC
DLYLVTDAGVENIASHAGSEIFKRIFFGEEDHIELYNAIMKGVGERYRTPFFNALRDYSK
EEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
QPTGMFHALPLARGKAILNSNWIGDLAQFYGMNLFMAETSATSGGLDSLLEPVGPLKHAQ
CCCCHHHHHHHHCCCHHHCCCCHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCHHHHHH
EYAARAFGAKRTFFATNGTSTCNKIVVQSLVREGDIVLVDRNCHKSHHYGLVLTGASAAY
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHH
LDSYPLNEYSMYGAVPIWHIKQTLLSFKRAGTLDRVKLVLLTNCTFDGVVYDVERVMMEC
HCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCHHHHHHHHHHHHH
LAIKPDLIFLWDEAWFAFASCHPIYRQRTAMANAAKLAERFKTPEYAREYAEWKDSIDWE
HHCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
DDQQLINTRLMPDPALARVRVYSTHSTHKTLTALRQGSMIHIWDQDFKEKSEEAFIEAYM
CHHHHHHHCCCCCCHHHEEEEEECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHH
THTSTSANYQILASLDVGRRQVEMEGYQLVQRQLELAMSLREQVMHHPLLKRHFHFLRVG
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
NIIPTAYRESGVNSYFDEGKGWANLEKAWSMDEFVMDPTRATLMIGMVGMDGDTFKNTEL
CCCCHHHHHCCCHHHHHCCCCCCCHHHHCCCHHHHCCCCHHEEEEEEEECCCCCCCCHHH
MNKYGIQINKTSRNTVLFIINIGTTRSAIAYLIEVLVKIARDVDRRVADMSSAERRIHLK
HHHHCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVNSLTQEQPPLPDFSAFHRAFRGQSLNPAIQTRDGNIRQAFFLSYEDSSCEYIDMQEAA
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEECCCCCEEEEEEEEECCCCCCEEEHHHHH
VAIASGRELVSALFVIPYPPGFPILVPGQVISSEILKFMAALDVKEIHGFRPELGFRVFT
HHHHHHHHHHHHHEEEECCCCCCEEECHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHH
QETLDRVLHAKESFESIMQYQQINNLRAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNTNSLSQHRSVWEIRSDSWINLVEDIGYLADLQINNQDRAKVLTRLRLTLDFLIPIES
CCCCCHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHEEHHH
YWAFPSKRVFAELCQYIEREDFTTARQLARRIHRALSAGTYRHDNKVLQSERELPSHIET
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHC
TSEQQARLSQPYFEVLIVDEMSPAEEDALRRRVISKRCSDDPFIFDIVVVPSFEDALIAS
CCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHH
LINFNLQAVVIRHGFPARSVNHVDMLERLFIDVDQDIESLPEMERGTLLGRHIAKLRPEL
HHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCC
DLYLVTDAGVENIASHAGSEIFKRIFFGEEDHIELYNAIMKGVGERYRTPFFNALRDYSK
EEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
QPTGMFHALPLARGKAILNSNWIGDLAQFYGMNLFMAETSATSGGLDSLLEPVGPLKHAQ
CCCCHHHHHHHHCCCHHHCCCCHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCHHHHHH
EYAARAFGAKRTFFATNGTSTCNKIVVQSLVREGDIVLVDRNCHKSHHYGLVLTGASAAY
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHH
LDSYPLNEYSMYGAVPIWHIKQTLLSFKRAGTLDRVKLVLLTNCTFDGVVYDVERVMMEC
HCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCHHHHHHHHHHHHH
LAIKPDLIFLWDEAWFAFASCHPIYRQRTAMANAAKLAERFKTPEYAREYAEWKDSIDWE
HHCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
DDQQLINTRLMPDPALARVRVYSTHSTHKTLTALRQGSMIHIWDQDFKEKSEEAFIEAYM
CHHHHHHHCCCCCCHHHEEEEEECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHH
THTSTSANYQILASLDVGRRQVEMEGYQLVQRQLELAMSLREQVMHHPLLKRHFHFLRVG
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
NIIPTAYRESGVNSYFDEGKGWANLEKAWSMDEFVMDPTRATLMIGMVGMDGDTFKNTEL
CCCCHHHHHCCCHHHHHCCCCCCCHHHHCCCHHHHCCCCHHEEEEEEEECCCCCCCCHHH
MNKYGIQINKTSRNTVLFIINIGTTRSAIAYLIEVLVKIARDVDRRVADMSSAERRIHLK
HHHHCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVNSLTQEQPPLPDFSAFHRAFRGQSLNPAIQTRDGNIRQAFFLSYEDSSCEYIDMQEAA
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEECCCCCEEEEEEEEECCCCCCEEEHHHHH
VAIASGRELVSALFVIPYPPGFPILVPGQVISSEILKFMAALDVKEIHGFRPELGFRVFT
HHHHHHHHHHHHHEEEECCCCCCEEECHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHH
QETLDRVLHAKESFESIMQYQQINNLRAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9226257; 9339543; 9278503; 9723924 [H]