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The map label for this gene is mdaB [H]

Identifier: 50086281

GI number: 50086281

Start: 3203073

End: 3203693

Strand: Direct

Name: mdaB [H]

Synonym: ACIAD3295

Alternate gene names: 50086281

Gene position: 3203073-3203693 (Clockwise)

Preceding gene: 50086280

Following gene: 50086282

Centisome position: 89.01

GC content: 41.38

Gene sequence:

>621_bases
ATGAGCAATATTCTAATTGTGAATGGCGCAAAAACCTTTGCCCACTCAAAAGGCGAACTTAACGATACCCTCACCACATT
TGCAGAAGAATTACTCAGCGAGTTGGGACATCAGGTTGATGTTTCACGTGCCGATACCAATTACAATATTGAGGCAGAAG
TAAAAAAGTATCTTTGGGCAGATGTGGTGATTTATCAAATGCCAGGCTGGTGGATGGGTGCGCCATGGACAGTCAAAAAA
TATATCGACGATATTTTTACAGCAGGACATGGCTCGTTATATGCAAGTGATGGACGTAGCCGTGCCGATCAAAGTAAGAA
ATATGGCTCAGGTGGTTTGATTCAGGGCAAAAAATATATGCTTTCGCTTACCTGGAATGCACCACTTGCAGCATTTGATG
ATCCAGAACAGTTTTTTCATGGCGTTGGTGTAGATGGCGTCTACCTGCCCTTTCATAAAGCTAATCAGTTTTTAGGCATG
CAAGCATTGCCAACATTTATTGTCAATGATGTAATCAAGATGCCGAATGTTGCTGAGTATCTGGCGATGTATCGTCAACA
TTTACTTGAAAATTTTAGCCAAAAGAATGTATCTCACTCGAAACTGGAGAATATCGCATGA

Upstream 100 bases:

>100_bases
ATTCATGATTTTATATCAATAATCTTTTGCATATTGCTGCATTTTTTAAATAGTTTCATCTGACTATACTGCCCATAAAT
CCACTTCTAATCTTACTTTT

Downstream 100 bases:

>100_bases
TTACTGTGATTGCAGAAATACGTACTCACACTGGTGCAGAGCATCGTCAACAGGTTTTAGCTTCATTTGAGCAAATTTTA
CCTCAAGTTTTGGCTGAGGT

Product: modulator of drug activity, electron transfer flavoprotein-NAD/FAD/quinone oxidoreductase

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSNILIVNGAKTFAHSKGELNDTLTTFAEELLSELGHQVDVSRADTNYNIEAEVKKYLWADVVIYQMPGWWMGAPWTVKK
YIDDIFTAGHGSLYASDGRSRADQSKKYGSGGLIQGKKYMLSLTWNAPLAAFDDPEQFFHGVGVDGVYLPFHKANQFLGM
QALPTFIVNDVIKMPNVAEYLAMYRQHLLENFSQKNVSHSKLENIA

Sequences:

>Translated_206_residues
MSNILIVNGAKTFAHSKGELNDTLTTFAEELLSELGHQVDVSRADTNYNIEAEVKKYLWADVVIYQMPGWWMGAPWTVKK
YIDDIFTAGHGSLYASDGRSRADQSKKYGSGGLIQGKKYMLSLTWNAPLAAFDDPEQFFHGVGVDGVYLPFHKANQFLGM
QALPTFIVNDVIKMPNVAEYLAMYRQHLLENFSQKNVSHSKLENIA
>Mature_205_residues
SNILIVNGAKTFAHSKGELNDTLTTFAEELLSELGHQVDVSRADTNYNIEAEVKKYLWADVVIYQMPGWWMGAPWTVKKY
IDDIFTAGHGSLYASDGRSRADQSKKYGSGGLIQGKKYMLSLTWNAPLAAFDDPEQFFHGVGVDGVYLPFHKANQFLGMQ
ALPTFIVNDVIKMPNVAEYLAMYRQHLLENFSQKNVSHSKLENIA

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=192, Percent_Identity=74.4791666666667, Blast_Score=315, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 23128; Mature: 22997

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILIVNGAKTFAHSKGELNDTLTTFAEELLSELGHQVDVSRADTNYNIEAEVKKYLWA
CCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHH
DVVIYQMPGWWMGAPWTVKKYIDDIFTAGHGSLYASDGRSRADQSKKYGSGGLIQGKKYM
HEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCEEECCEEE
LSLTWNAPLAAFDDPEQFFHGVGVDGVYLPFHKANQFLGMQALPTFIVNDVIKMPNVAEY
EEEEECCCCCCCCCHHHHHHCCCCCCEEECHHHHHHHHCHHHHHHHHHHHHHCCCCHHHH
LAMYRQHLLENFSQKNVSHSKLENIA
HHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
SNILIVNGAKTFAHSKGELNDTLTTFAEELLSELGHQVDVSRADTNYNIEAEVKKYLWA
CCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHH
DVVIYQMPGWWMGAPWTVKKYIDDIFTAGHGSLYASDGRSRADQSKKYGSGGLIQGKKYM
HEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCEEECCEEE
LSLTWNAPLAAFDDPEQFFHGVGVDGVYLPFHKANQFLGMQALPTFIVNDVIKMPNVAEY
EEEEECCCCCCCCCHHHHHHCCCCCCEEECHHHHHHHHCHHHHHHHHHHHHHCCCCHHHH
LAMYRQHLLENFSQKNVSHSKLENIA
HHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]