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The map label for this gene is etfD [H]

Identifier: 50086251

GI number: 50086251

Start: 3171439

End: 3173151

Strand: Direct

Name: etfD [H]

Synonym: ACIAD3259

Alternate gene names: 50086251

Gene position: 3171439-3173151 (Clockwise)

Preceding gene: 50086245

Following gene: 50086253

Centisome position: 88.13

GC content: 47.87

Gene sequence:

>1713_bases
ATGGAACACATCGAACGCGAAGCGATGGAGTTTGACGTAGTGATCGTTGGTGCTGGACCTGCCGGTCTATCTGCTGCGAT
TAAAATTCGCCAACTCGCGATTGAAAATAATTTACCTGATCTGTCCGTCTGCGTCGTCGAAAAAGGTTCCGAAGTAGGTG
CTCACATCCTCTCTGGTGCAGTACTTGAACCTCGCGCCATCAATGAACTTTTCCCCAACTGGAAAGAAGAAGGTGCGCCG
CTCAATGTCCCGGTGACTGAGGATAAAACCTATTTCCTGATGTCGGATGAGAAATCTCAGGAAGCACCGCACTGGATGGT
GCCTAAAACCATGCACAATGATGGCAATTATGTCATCTCGCTGGGCAATGTGGTGCGCTGGTTAGGCCAGAAGGCGGAAG
AGCTTGAAGTCTCGATTTTTCCAGGCTTTGCTGCTGCCGAGATTCTGTATCATGCTGATGGTACGGTTAAAGGCATTCAG
ACCGGTGATATGGGTATTGGCAAGGATGGCGAACCAACGCATAACTTTGCGCCAGGTTATGAACTGCATGCCAAATATAC
GCTGTTTGCCGAAGGTTGCCGTGGTCATTTAGGCAAGCGCCTGATCAATAAGTTTAATCTGGATCAGGAGGCTGACCCGC
AGCATTACGGTATCGGGATTAAAGAGCTTTGGGAAATCGATCCTGCCAAGCATAAACCAGGTCTGGTGATGCATGGTTCT
GGCTGGCCATTGTCTGAAACGGGTTCTTCTGGTGGCTGGTGGTTATATCATGCCGAGAATAATCAGGTGACTTTGGGCAT
GATCGTGGATTTATCATATGAAAATCCGCATATGTTCCCGTTTATGGAAATGCAGCGCTGGAAAACCCACCCACTGATCA
AACAGTATCTGGAAGGTGGTAAGCGTATTTCTTACGGTGCACGTGCTGTGGTCAAAGGTGGCTTAAACTCACTGCCCAAG
TTGACTTTCCCAGGTGGTTGTCTGATTGGTGATGATGCAGGCTTTTTGAACTTTGCGAAAATCAAAGGCTCACATACGGC
CATGAAATCTGGCATGCTTTGCGGTGAAGCCGTATTTGAAGCGATTGCACGTGGTGTCGAAAAAGGCGGTGATCTAGCCA
TTGCCCGTGTCGTTGAAGGTGAAGATTTGTTTGATAAGGAGCTCACCGCCTACACGCAGAAATTTGATAAGAGCTGGCTT
AAAGAAGAGTTACACCGCAGTCGTAATTTTGGTCCAGCCATGCACAAGTTTGGTTTATGGATTGGTGGTGCATTTAACTT
TGTGGATCAGAACATTTTTAAAGTTCCATTCACTCTGCACGATCTTCAGCCTGACTACAGCGCACTGAAAACTCAGGATC
AAGCCACCTTTAAACCGAATTATCCAAAGCCAGATGGCAAGCTGACGTTTGACCGTTTGTCTTCGGTATTTGTATCCAAT
ACGGTACATGAAGAAAATCAGCCATCACACTTGAAACTGACCGATGCCAGTATTCCTGTGGCGGTGAATCTACCGAGATG
GGATGAGCCAGCTCAGCGCTACTGCCCTGCGGGTGTGTACGAAATTGTGGATGAAGGTGAAGGCAACAAGCGTTTTCAGA
TCAATGCAGCCAACTGTGTGCACTGCAAAACCTGTGATATCAAGGATCCATCTCAGAATATCACATGGGTGACGCCTGAA
GGTGGCGGTGGGCCGAATTACCCAAATATGTGA

Upstream 100 bases:

>100_bases
AAGACACGATCATCGGCTTGTGTCTAGACATTAAGAACACTCATGGCAGCACCGAATGTTGAATTACGGTTGCCACCCTT
AGCAATATGAGGAGTCCTAC

Downstream 100 bases:

>100_bases
TTTTAGAATAATTTTCATCTGCAAAATATTGCTTTTGCACTGACATAAAAAAACTGGATACAAGATCCAGTTTTTTTATG
TCTAAAATTATTGATTCAAT

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MEHIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGAVLEPRAINELFPNWKEEGAP
LNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVISLGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQ
TGDMGIGKDGEPTHNFAPGYELHAKYTLFAEGCRGHLGKRLINKFNLDQEADPQHYGIGIKELWEIDPAKHKPGLVMHGS
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGGKRISYGARAVVKGGLNSLPK
LTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFEAIARGVEKGGDLAIARVVEGEDLFDKELTAYTQKFDKSWL
KEELHRSRNFGPAMHKFGLWIGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCVHCKTCDIKDPSQNITWVTPE
GGGGPNYPNM

Sequences:

>Translated_570_residues
MEHIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGAVLEPRAINELFPNWKEEGAP
LNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVISLGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQ
TGDMGIGKDGEPTHNFAPGYELHAKYTLFAEGCRGHLGKRLINKFNLDQEADPQHYGIGIKELWEIDPAKHKPGLVMHGS
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGGKRISYGARAVVKGGLNSLPK
LTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFEAIARGVEKGGDLAIARVVEGEDLFDKELTAYTQKFDKSWL
KEELHRSRNFGPAMHKFGLWIGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCVHCKTCDIKDPSQNITWVTPE
GGGGPNYPNM
>Mature_570_residues
MEHIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGAVLEPRAINELFPNWKEEGAP
LNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVISLGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQ
TGDMGIGKDGEPTHNFAPGYELHAKYTLFAEGCRGHLGKRLINKFNLDQEADPQHYGIGIKELWEIDPAKHKPGLVMHGS
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGGKRISYGARAVVKGGLNSLPK
LTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFEAIARGVEKGGDLAIARVVEGEDLFDKELTAYTQKFDKSWL
KEELHRSRNFGPAMHKFGLWIGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCVHCKTCDIKDPSQNITWVTPE
GGGGPNYPNM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=574, Percent_Identity=51.5679442508711, Blast_Score=560, Evalue=1e-159,
Organism=Escherichia coli, GI1787991, Length=335, Percent_Identity=26.5671641791045, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786227, Length=335, Percent_Identity=25.9701492537313, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082155, Length=303, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144720, Length=579, Percent_Identity=50.4317789291883, Blast_Score=547, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6324932, Length=578, Percent_Identity=42.3875432525952, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24652256, Length=575, Percent_Identity=51.1304347826087, Blast_Score=552, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 63046; Mature: 63046

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGA
CCCHHHHCEEEEEEEEECCCCCCHHHHEEEEEHHHCCCCCEEEEEEECCCHHHHHHHCCC
VLEPRAINELFPNWKEEGAPLNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVIS
CCCCHHHHHHCCCHHHCCCEECCEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEE
LGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQTGDMGIGKDGEPTHNFAPGY
HHHHHHHHCCCCHHEEEEEECCHHHEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCE
ELHAKYTLFAEGCRGHLGKRLINKFNLDQEADPQHYGIGIKELWEIDPAKHKPGLVMHGS
EEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHCCCCCCCCCCEEEECC
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGG
CCCCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHCCC
KRISYGARAVVKGGLNSLPKLTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFE
CEECCCCHHHHHCCCCCCCCEECCCCEEEECCCCCEEEEEECCCHHHHHHCCHHHHHHHH
AIARGVEKGGDLAIARVVEGEDLFDKELTAYTQKFDKSWLKEELHRSRNFGPAMHKFGLW
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
IGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
ECCCHHHHCCCEEECCEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHC
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCV
CCCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCCHHHHHHCCCCCCEEEEECCCEE
HCKTCDIKDPSQNITWVTPEGGGGPNYPNM
EEEECCCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MEHIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGA
CCCHHHHCEEEEEEEEECCCCCCHHHHEEEEEHHHCCCCCEEEEEEECCCHHHHHHHCCC
VLEPRAINELFPNWKEEGAPLNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVIS
CCCCHHHHHHCCCHHHCCCEECCEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEE
LGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQTGDMGIGKDGEPTHNFAPGY
HHHHHHHHCCCCHHEEEEEECCHHHEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCE
ELHAKYTLFAEGCRGHLGKRLINKFNLDQEADPQHYGIGIKELWEIDPAKHKPGLVMHGS
EEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHCCCCCCCCCCEEEECC
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGG
CCCCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHCCC
KRISYGARAVVKGGLNSLPKLTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFE
CEECCCCHHHHHCCCCCCCCEECCCCEEEECCCCCEEEEEECCCHHHHHHCCHHHHHHHH
AIARGVEKGGDLAIARVVEGEDLFDKELTAYTQKFDKSWLKEELHRSRNFGPAMHKFGLW
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
IGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
ECCCHHHHCCCEEECCEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHC
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCV
CCCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCCHHHHHHCCCCCCEEEEECCCEE
HCKTCDIKDPSQNITWVTPEGGGGPNYPNM
EEEECCCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]