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The map label for this gene is corA [H]

Identifier: 50086234

GI number: 50086234

Start: 3154524

End: 3155612

Strand: Direct

Name: corA [H]

Synonym: ACIAD3239

Alternate gene names: 50086234

Gene position: 3154524-3155612 (Clockwise)

Preceding gene: 50086231

Following gene: 50086243

Centisome position: 87.66

GC content: 42.33

Gene sequence:

>1089_bases
GTGTTTTTGGTCAAATCCTTGTCTAAAATACACGCATTCATTTACCCCCGTACTGCGCAAGGGAGAAAAGACACTATGCT
TGAAGCCTTTTATGCCACAGAGCGCGGTAGTCTGGAAGATGCCACCATCAACGGTGGTTTTGATCTTCATCCAGAACTGG
TCTGGATTGACCTGATTTCACCCTCCCCAGAAGAACAGCAATGGATACTCGATGCTTACGATCGAAACCTCCCAACACTG
AAATCTCTTGAAGACATTTCCTCATCTGCCCGATTCTACCGCGATGATGATGGAATTTTGCATATCAGCACCTATTTTTT
AACGAAAAATAAAAACTATCAAGTAGATGGTGATACAGAAGAATCCAGTAATATTTTAGCGATGGTTCAAACAGTTGCAT
TTATCTTGCATAAAGACCGTCTATTTACTTTGCGTAGTGAAAAACTAGTGGCCTTTCGTGCCTTTCGTGCTCGCGCCCGA
CGTAATGACTATGATATGGATTATAAAGATCCCACTTGGATTTTACTTGGACTGCTTGAAGCCAAATTAGATGAGCTTGC
GGATATCCTAGAAGATATCCATAAAGATCTGGAAAAATATTCCACCGAAGTACTTAATAACCATCATCGTGAACAGATTC
TTGATCTGGATGACATGATTACACGACTGGCACAACAAGAAGACGTTCTAGGTAAAGCGCAGCTCTGTCTGATCGATTTA
CGTCGTGTACTGACCTTTTTAGCACGTCCACGCGCGTTAGGTAGTCATATTTATGATGCGGACATTCGAGAGCTTAGTGA
AGATGTTCGCTCACTGGTCGAACATGATGCCTTCTTGTTTCAGAAAGTTCGCTTCTTGCTCGACACCACGTCGGGATTTA
TTAACACCGAACAAAACGATACGATTCGTCGCTTCTCGATTTTACCTAGTATGCTTGCGCCACCAATGTTGGTGGCCAGT
ATTTATGGAATGAACACCCAAGAACTACCCTTTGCACATGGCACCATGAGCTTTTTAACTGTTGCAATGATTATTATCGT
GTCATTTGTGGGTCCAATGATTTATTTCCGCTGGAAGAAATGGGTTTAA

Upstream 100 bases:

>100_bases
ATACAAACAGAATTCATAAATTTTTTTACCATTTTGTTAATTTGTCATGCTTACAAAGTAAGCTTTAGGAAAAATTTTTT
CGAAATTAACCGAACAACAA

Downstream 100 bases:

>100_bases
ACTTTTGATAAAAAAAGCACCGAACCTCGGTGCTTTTTTATTGGTAGCTTACTAGCGATGAAGTAGCGTCAGGTCATCTT
GTAAATGACAGGACTGAATA

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MFLVKSLSKIHAFIYPRTAQGRKDTMLEAFYATERGSLEDATINGGFDLHPELVWIDLISPSPEEQQWILDAYDRNLPTL
KSLEDISSSARFYRDDDGILHISTYFLTKNKNYQVDGDTEESSNILAMVQTVAFILHKDRLFTLRSEKLVAFRAFRARAR
RNDYDMDYKDPTWILLGLLEAKLDELADILEDIHKDLEKYSTEVLNNHHREQILDLDDMITRLAQQEDVLGKAQLCLIDL
RRVLTFLARPRALGSHIYDADIRELSEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLVAS
IYGMNTQELPFAHGTMSFLTVAMIIIVSFVGPMIYFRWKKWV

Sequences:

>Translated_362_residues
MFLVKSLSKIHAFIYPRTAQGRKDTMLEAFYATERGSLEDATINGGFDLHPELVWIDLISPSPEEQQWILDAYDRNLPTL
KSLEDISSSARFYRDDDGILHISTYFLTKNKNYQVDGDTEESSNILAMVQTVAFILHKDRLFTLRSEKLVAFRAFRARAR
RNDYDMDYKDPTWILLGLLEAKLDELADILEDIHKDLEKYSTEVLNNHHREQILDLDDMITRLAQQEDVLGKAQLCLIDL
RRVLTFLARPRALGSHIYDADIRELSEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLVAS
IYGMNTQELPFAHGTMSFLTVAMIIIVSFVGPMIYFRWKKWV
>Mature_362_residues
MFLVKSLSKIHAFIYPRTAQGRKDTMLEAFYATERGSLEDATINGGFDLHPELVWIDLISPSPEEQQWILDAYDRNLPTL
KSLEDISSSARFYRDDDGILHISTYFLTKNKNYQVDGDTEESSNILAMVQTVAFILHKDRLFTLRSEKLVAFRAFRARAR
RNDYDMDYKDPTWILLGLLEAKLDELADILEDIHKDLEKYSTEVLNNHHREQILDLDDMITRLAQQEDVLGKAQLCLIDL
RRVLTFLARPRALGSHIYDADIRELSEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLVAS
IYGMNTQELPFAHGTMSFLTVAMIIIVSFVGPMIYFRWKKWV

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=310, Percent_Identity=38.7096774193548, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41910; Mature: 41910

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVKSLSKIHAFIYPRTAQGRKDTMLEAFYATERGSLEDATINGGFDLHPELVWIDLIS
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCEEEEEEEC
PSPEEQQWILDAYDRNLPTLKSLEDISSSARFYRDDDGILHISTYFLTKNKNYQVDGDTE
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCEEEEEEEEEECCCCEEECCCCC
ESSNILAMVQTVAFILHKDRLFTLRSEKLVAFRAFRARARRNDYDMDYKDPTWILLGLLE
CCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AKLDELADILEDIHKDLEKYSTEVLNNHHREQILDLDDMITRLAQQEDVLGKAQLCLIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
RRVLTFLARPRALGSHIYDADIRELSEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQND
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TIRRFSILPSMLAPPMLVASIYGMNTQELPFAHGTMSFLTVAMIIIVSFVGPMIYFRWKK
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
WV
CC
>Mature Secondary Structure
MFLVKSLSKIHAFIYPRTAQGRKDTMLEAFYATERGSLEDATINGGFDLHPELVWIDLIS
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCEEEEEEEC
PSPEEQQWILDAYDRNLPTLKSLEDISSSARFYRDDDGILHISTYFLTKNKNYQVDGDTE
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCEEEEEEEEEECCCCEEECCCCC
ESSNILAMVQTVAFILHKDRLFTLRSEKLVAFRAFRARARRNDYDMDYKDPTWILLGLLE
CCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AKLDELADILEDIHKDLEKYSTEVLNNHHREQILDLDDMITRLAQQEDVLGKAQLCLIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
RRVLTFLARPRALGSHIYDADIRELSEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQND
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TIRRFSILPSMLAPPMLVASIYGMNTQELPFAHGTMSFLTVAMIIIVSFVGPMIYFRWKK
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
WV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA