Click here to switch to the map view.

The map label for this gene is secY [H]

Identifier: 50086195

GI number: 50086195

Start: 3124591

End: 3125949

Strand: Reverse

Name: secY [H]

Synonym: ACIAD3199

Alternate gene names: 50086195

Gene position: 3125949-3124591 (Counterclockwise)

Preceding gene: 50086196

Following gene: 50086194

Centisome position: 86.87

GC content: 41.35

Gene sequence:

>1359_bases
GTGTCTATGTCTCCTAGTTCTTCAGGTCATGTCAACATGATGAAAGGACAGCCATTTCATGTGAAATACCGTGAAATTAT
TCGCCGATTAATGTTCTTGATTGGCGCATTGTTGGTCTTTCGACTAGGAGCGCATATTCCGTTGCCGGGTATTGATAATG
TAGCGCTAGCACGTTTTTTTAAAGCCAATGAAGGTACTTTCTTGGGTTTATTTAACATGTTCTCTGGCGGTGCATTGGAA
CGTATGTCAATTCTAGCATTGGGAATCATGCCGTATATCTCTGCATCGATTATCGTGCAGTTGATGTCTACAGTGGTTCC
TTCGCTAGAAGCTTTGAAGAAAGAAGGCGAGCAAGGCAAACGTAAAATTAATCAGTACACGCGTTATGGCACCTTATTAC
TTGCGCTTGTGCAAGGTGTGGGGATGTGTGCTGGTCTGATCAGTCAAGGCATTACCTTGACTTCAGGCTTGGCATTTTAT
ATTCCAGCAGTAACCTCTTTGGTTGCTGGAACAATGTTCCTGATGTGGTTGGGAGAGCAAATTACCGAACGTGGTATCGG
TAATGGTATCTCCATGATCATCTTTGCAGGAATTGTTGCAGGTTTACCGAACCAAGTGATTCAGGCTTTTACATCTGTTC
AAAATGGACAGGGCAGTTTAATTGGAATTGTCGTATTTGCATTATTATCACTCGCGGTACTTGCGGCAATTGTGTTTATT
GAAAAAGCACAACGTCGTATTCCTGTTAACTACGCACAAAAGCAACAAGGTCGTCGGATATTTACTGCACAGCAAACTCA
TTTGCCATTAAAAATTAATATGGCAGGGGTTATTCCAGCTATTTTTGCCAGCTCACTGTTATTATTTCCAGCGAGTTTGG
GGCAATGGCTAGGTAGTGCAGATCCAAATGCGGGTATTGTAAAGCGTAGCTTGCAAGATTTGGCACTCGTGTTATCGCCT
GGACAGCCGTTGTATTTAATGCTCTTTGGTACGTTAATTATTTTCTTCTGTTATTTTTATACGGCATTGGTATTTAGTCC
GAAAGAAGTGTCAGAAAACTTAAAACGTAGCGGTGCATATGTACCTGGTATACGCCCAGGTGAGCAAACGGCTCGTTATT
TAGATCATATTCTTAATCGTTTGACGTTTATTGGTGCGATTTATATTACGGTTGTGTGTTTGATGCCAATGATCCTACAA
AATTCGTTTGGTATTCCATTCCATTTGGGTGGAACATCTTTACTGATTGTAGTGGTTGTGGTGATGGACTTTATGGCCCA
ATTGCAAGCACATTTGACCTCGCATCAATATGATAATCAATCGTTAATGAGAAAAACGACTGCTCATCCTAAGGGATAA

Upstream 100 bases:

>100_bases
TGAAGTAACTCGCGCGTTTACTGTGCAAGGTGTTGCTTTGACTAAAGGCGCTCAAGCTGCAATCGAAGCTGCTGGCGGTA
AAGTCGAGGAGTAATGCCGA

Downstream 100 bases:

>100_bases
GCGCACTTAGAGGTTTCATCATGAAAGTACAAGCTTCTGTAAAGAAAATTTGTGGTAGCTGTAAAGTTATCCGTCGTAAT
GGGGTTATTCGCGTAATTTG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSMSPSSSGHVNMMKGQPFHVKYREIIRRLMFLIGALLVFRLGAHIPLPGIDNVALARFFKANEGTFLGLFNMFSGGALE
RMSILALGIMPYISASIIVQLMSTVVPSLEALKKEGEQGKRKINQYTRYGTLLLALVQGVGMCAGLISQGITLTSGLAFY
IPAVTSLVAGTMFLMWLGEQITERGIGNGISMIIFAGIVAGLPNQVIQAFTSVQNGQGSLIGIVVFALLSLAVLAAIVFI
EKAQRRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWLGSADPNAGIVKRSLQDLALVLSP
GQPLYLMLFGTLIIFFCYFYTALVFSPKEVSENLKRSGAYVPGIRPGEQTARYLDHILNRLTFIGAIYITVVCLMPMILQ
NSFGIPFHLGGTSLLIVVVVVMDFMAQLQAHLTSHQYDNQSLMRKTTAHPKG

Sequences:

>Translated_452_residues
MSMSPSSSGHVNMMKGQPFHVKYREIIRRLMFLIGALLVFRLGAHIPLPGIDNVALARFFKANEGTFLGLFNMFSGGALE
RMSILALGIMPYISASIIVQLMSTVVPSLEALKKEGEQGKRKINQYTRYGTLLLALVQGVGMCAGLISQGITLTSGLAFY
IPAVTSLVAGTMFLMWLGEQITERGIGNGISMIIFAGIVAGLPNQVIQAFTSVQNGQGSLIGIVVFALLSLAVLAAIVFI
EKAQRRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWLGSADPNAGIVKRSLQDLALVLSP
GQPLYLMLFGTLIIFFCYFYTALVFSPKEVSENLKRSGAYVPGIRPGEQTARYLDHILNRLTFIGAIYITVVCLMPMILQ
NSFGIPFHLGGTSLLIVVVVVMDFMAQLQAHLTSHQYDNQSLMRKTTAHPKG
>Mature_451_residues
SMSPSSSGHVNMMKGQPFHVKYREIIRRLMFLIGALLVFRLGAHIPLPGIDNVALARFFKANEGTFLGLFNMFSGGALER
MSILALGIMPYISASIIVQLMSTVVPSLEALKKEGEQGKRKINQYTRYGTLLLALVQGVGMCAGLISQGITLTSGLAFYI
PAVTSLVAGTMFLMWLGEQITERGIGNGISMIIFAGIVAGLPNQVIQAFTSVQNGQGSLIGIVVFALLSLAVLAAIVFIE
KAQRRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWLGSADPNAGIVKRSLQDLALVLSPG
QPLYLMLFGTLIIFFCYFYTALVFSPKEVSENLKRSGAYVPGIRPGEQTARYLDHILNRLTFIGAIYITVVCLMPMILQN
SFGIPFHLGGTSLLIVVVVVMDFMAQLQAHLTSHQYDNQSLMRKTTAHPKG

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=419, Percent_Identity=58.7112171837709, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 49184; Mature: 49053

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00755 SECY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSPSSSGHVNMMKGQPFHVKYREIIRRLMFLIGALLVFRLGAHIPLPGIDNVALARFF
CCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KANEGTFLGLFNMFSGGALERMSILALGIMPYISASIIVQLMSTVVPSLEALKKEGEQGK
HCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKINQYTRYGTLLLALVQGVGMCAGLISQGITLTSGLAFYIPAVTSLVAGTMFLMWLGEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITERGIGNGISMIIFAGIVAGLPNQVIQAFTSVQNGQGSLIGIVVFALLSLAVLAAIVFI
HHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
EKAQRRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWLGSA
HHHHHCCCCCHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPNAGIVKRSLQDLALVLSPGQPLYLMLFGTLIIFFCYFYTALVFSPKEVSENLKRSGAY
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
VPGIRPGEQTARYLDHILNRLTFIGAIYITVVCLMPMILQNSFGIPFHLGGTSLLIVVVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHH
VMDFMAQLQAHLTSHQYDNQSLMRKTTAHPKG
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
SMSPSSSGHVNMMKGQPFHVKYREIIRRLMFLIGALLVFRLGAHIPLPGIDNVALARFF
CCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KANEGTFLGLFNMFSGGALERMSILALGIMPYISASIIVQLMSTVVPSLEALKKEGEQGK
HCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKINQYTRYGTLLLALVQGVGMCAGLISQGITLTSGLAFYIPAVTSLVAGTMFLMWLGEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITERGIGNGISMIIFAGIVAGLPNQVIQAFTSVQNGQGSLIGIVVFALLSLAVLAAIVFI
HHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
EKAQRRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWLGSA
HHHHHCCCCCHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPNAGIVKRSLQDLALVLSPGQPLYLMLFGTLIIFFCYFYTALVFSPKEVSENLKRSGAY
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
VPGIRPGEQTARYLDHILNRLTFIGAIYITVVCLMPMILQNSFGIPFHLGGTSLLIVVVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHH
VMDFMAQLQAHLTSHQYDNQSLMRKTTAHPKG
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]