Click here to switch to the map view.

The map label for this gene is ycgM [H]

Identifier: 50086172

GI number: 50086172

Start: 3099662

End: 3100306

Strand: Reverse

Name: ycgM [H]

Synonym: ACIAD3172

Alternate gene names: 50086172

Gene position: 3100306-3099662 (Counterclockwise)

Preceding gene: 50086173

Following gene: 50086170

Centisome position: 86.15

GC content: 43.1

Gene sequence:

>645_bases
CTGATGAATACACGTCCATCAAAAATTATTTGTATCGGAAGAAGCTATGCTGCACATGCAAAAGAATTAGGCAATGCGAT
TTCAGATCGTCCAGTCCTGTTTATTAAGCCACCGAGTAGTTTAATTGGTTTGGAACAGGGCATTGAATGGAATACCAAAC
ATGGCAGTTGCCATTTTGAGTGTGAGTTGACTCTACGAATTGACCAGCCTCTTAAAAATGAAACAGACCCCCAAAAAGCT
TTAGCTGCAATTGGCGCCGTAACGATGGGATTGGATTTGACTTTGCGGGATTTACAAGATGACTTGAAAAGTAAAGGGCA
TCCGTGGGAGCGTTGTAAAGCATTTGATGGTGCATGTGTATTGGCAGATTGGGTTGATGTGAGTGAAATTGAAGACTGGA
AGCATGTGACCTATACCTTTCATATCAATGATCAGTTACGTCAGGAAGGCGATACAGCATATCTACTCTTAAGCATTGGT
GAATACCTGTGTGATATTAGTCAGGCATTTAGCATCGAAGCGGGCGATGTGGTCATGACAGGCACACCAGCAGGTGTAGG
GCCGTTGCATCACGGCGATCAGCTTAAAATGACGCTTCATGGTAAAACCCAGCAATTTGTGTGGAACACCTTTGTACATG
AATAA

Upstream 100 bases:

>100_bases
ATTGTACCGAAGCGCGCATTAGCTGATACTTCGGATAAAACCAAATTTGAAAATGCCTTTAAATCGTAATTGATTAAAAT
AAACCAGCATAAAAGGAAAT

Downstream 100 bases:

>100_bases
TGTTGTGATCCGTTTTTGCATGAATAGCCTGTATTGTTAACAGGCCATTTTGCTTTTATAGGTCTATATGATTGGATATC
TCTATGAGATTTTAATCTGG

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MMNTRPSKIICIGRSYAAHAKELGNAISDRPVLFIKPPSSLIGLEQGIEWNTKHGSCHFECELTLRIDQPLKNETDPQKA
LAAIGAVTMGLDLTLRDLQDDLKSKGHPWERCKAFDGACVLADWVDVSEIEDWKHVTYTFHINDQLRQEGDTAYLLLSIG
EYLCDISQAFSIEAGDVVMTGTPAGVGPLHHGDQLKMTLHGKTQQFVWNTFVHE

Sequences:

>Translated_214_residues
MMNTRPSKIICIGRSYAAHAKELGNAISDRPVLFIKPPSSLIGLEQGIEWNTKHGSCHFECELTLRIDQPLKNETDPQKA
LAAIGAVTMGLDLTLRDLQDDLKSKGHPWERCKAFDGACVLADWVDVSEIEDWKHVTYTFHINDQLRQEGDTAYLLLSIG
EYLCDISQAFSIEAGDVVMTGTPAGVGPLHHGDQLKMTLHGKTQQFVWNTFVHE
>Mature_214_residues
MMNTRPSKIICIGRSYAAHAKELGNAISDRPVLFIKPPSSLIGLEQGIEWNTKHGSCHFECELTLRIDQPLKNETDPQKA
LAAIGAVTMGLDLTLRDLQDDLKSKGHPWERCKAFDGACVLADWVDVSEIEDWKHVTYTFHINDQLRQEGDTAYLLLSIG
EYLCDISQAFSIEAGDVVMTGTPAGVGPLHHGDQLKMTLHGKTQQFVWNTFVHE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=33.1632653061224, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI13654274, Length=193, Percent_Identity=33.160621761658, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI215422413, Length=193, Percent_Identity=33.160621761658, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI156231349, Length=185, Percent_Identity=28.6486486486486, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI40786394, Length=185, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1787428, Length=198, Percent_Identity=42.4242424242424, Blast_Score=166, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=37.7551020408163, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324161, Length=219, Percent_Identity=35.6164383561644, Blast_Score=127, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28571789, Length=189, Percent_Identity=25.9259259259259, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28572127, Length=185, Percent_Identity=25.9459459459459, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23843; Mature: 23843

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTRPSKIICIGRSYAAHAKELGNAISDRPVLFIKPPSSLIGLEQGIEWNTKHGSCHFE
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCEECCCCCCEEEE
CELTLRIDQPLKNETDPQKALAAIGAVTMGLDLTLRDLQDDLKSKGHPWERCKAFDGACV
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHCCCCCEE
LADWVDVSEIEDWKHVTYTFHINDQLRQEGDTAYLLLSIGEYLCDISQAFSIEAGDVVMT
EEECCCHHHCCCCEEEEEEEEECHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCCCCEEEE
GTPAGVGPLHHGDQLKMTLHGKTQQFVWNTFVHE
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCC
>Mature Secondary Structure
MMNTRPSKIICIGRSYAAHAKELGNAISDRPVLFIKPPSSLIGLEQGIEWNTKHGSCHFE
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCEECCCCCCEEEE
CELTLRIDQPLKNETDPQKALAAIGAVTMGLDLTLRDLQDDLKSKGHPWERCKAFDGACV
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHCCCCCEE
LADWVDVSEIEDWKHVTYTFHINDQLRQEGDTAYLLLSIGEYLCDISQAFSIEAGDVVMT
EEECCCHHHCCCCEEEEEEEEECHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCCCCEEEE
GTPAGVGPLHHGDQLKMTLHGKTQQFVWNTFVHE
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]