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The map label for this gene is orn

Identifier: 50086122

GI number: 50086122

Start: 3048223

End: 3048774

Strand: Reverse

Name: orn

Synonym: ACIAD3118

Alternate gene names: 50086122

Gene position: 3048774-3048223 (Counterclockwise)

Preceding gene: 50086127

Following gene: 50086121

Centisome position: 84.72

GC content: 39.49

Gene sequence:

>552_bases
ATGAGCAGCACACAGGATACGCGGTTAATCTGGATTGACCTTGAAATGACAGGTTTAGACACAGATAACGATCAAATTAT
TGAAATTGCCACGATTATTACAGATGATCATTTAAATATTGTTGCTGAAGGTCCTGTTCTTGCTGTTCATCAACCTGATC
GGATTTTAAATGCAATGGATGAATGGAACACGCGTCAGCACGGTCAGTCAGGTTTGATTGAACGTGTTCGCCGCAGCAAG
CTGACGGCACGAGATGTAGAATTGCAGACACTTGAGTTCTTAAAAAAATGGGTTAATCCGAAAACTTCTCCGATGTGCGG
TAACTCGATCTGTCAAGATCGTCGTTTTATGCATCGCTTGATGCCAGAGTTAGAACAGTATTTTCATTATCGTAATCTGG
ATGTCTCATCGGTGAAAGAATTAGCAAAACGCTGGCGTCCAGAGATCATGAGTGGCTTAAAGAAAAATGCATCTCATTTG
GCGATGGATGATATTCGTGACTCTATTTCAGAGCTAAAATATTATCGTGAGTATTTTTTTATTAAAAATTAA

Upstream 100 bases:

>100_bases
CCAAGGTGGCAAAAATAGCATGAACTGGCTATGGAATTACAGCCAAGATGAGAGAAATTTGCTACTATTGATGTTTTTGA
CGCTTTAAGATTTGACATTT

Downstream 100 bases:

>100_bases
TACTTGGATTATGATTTTAAAGTAAAGGCCATTCGGGTAGTTAGCACGATATGGTCTTTTTTATTGGGCACGAAGCTTAT
CTTTATCAATATAAAAATTT

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSSTQDTRLIWIDLEMTGLDTDNDQIIEIATIITDDHLNIVAEGPVLAVHQPDRILNAMDEWNTRQHGQSGLIERVRRSK
LTARDVELQTLEFLKKWVNPKTSPMCGNSICQDRRFMHRLMPELEQYFHYRNLDVSSVKELAKRWRPEIMSGLKKNASHL
AMDDIRDSISELKYYREYFFIKN

Sequences:

>Translated_183_residues
MSSTQDTRLIWIDLEMTGLDTDNDQIIEIATIITDDHLNIVAEGPVLAVHQPDRILNAMDEWNTRQHGQSGLIERVRRSK
LTARDVELQTLEFLKKWVNPKTSPMCGNSICQDRRFMHRLMPELEQYFHYRNLDVSSVKELAKRWRPEIMSGLKKNASHL
AMDDIRDSISELKYYREYFFIKN
>Mature_182_residues
SSTQDTRLIWIDLEMTGLDTDNDQIIEIATIITDDHLNIVAEGPVLAVHQPDRILNAMDEWNTRQHGQSGLIERVRRSKL
TARDVELQTLEFLKKWVNPKTSPMCGNSICQDRRFMHRLMPELEQYFHYRNLDVSSVKELAKRWRPEIMSGLKKNASHLA
MDDIRDSISELKYYREYFFIKN

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=174, Percent_Identity=47.7011494252874, Blast_Score=183, Evalue=6e-47,
Organism=Escherichia coli, GI87082382, Length=177, Percent_Identity=62.7118644067797, Blast_Score=244, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17557752, Length=178, Percent_Identity=44.9438202247191, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6323088, Length=181, Percent_Identity=40.3314917127072, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21355135, Length=183, Percent_Identity=45.3551912568306, Blast_Score=177, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_ACIAD (Q6F805)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047632.1
- ProteinModelPortal:   Q6F805
- SMR:   Q6F805
- STRING:   Q6F805
- GeneID:   2879679
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3118
- NMPDR:   fig|62977.3.peg.2825
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   Q6F805
- ProtClustDB:   PRK05359
- BioCyc:   ASP62977:ACIAD3118-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21552; Mature: 21421

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 130-130

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTQDTRLIWIDLEMTGLDTDNDQIIEIATIITDDHLNIVAEGPVLAVHQPDRILNAMD
CCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEEECCCCEEEECCCEEEEECCHHHHHHHH
EWNTRQHGQSGLIERVRRSKLTARDVELQTLEFLKKWVNPKTSPMCGNSICQDRRFMHRL
HCCCHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MPELEQYFHYRNLDVSSVKELAKRWRPEIMSGLKKNASHLAMDDIRDSISELKYYREYFF
HHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IKN
CCC
>Mature Secondary Structure 
SSTQDTRLIWIDLEMTGLDTDNDQIIEIATIITDDHLNIVAEGPVLAVHQPDRILNAMD
CCCCCCEEEEEEEEEECCCCCCCCEEEEEEEEECCCCEEEECCCEEEEECCHHHHHHHH
EWNTRQHGQSGLIERVRRSKLTARDVELQTLEFLKKWVNPKTSPMCGNSICQDRRFMHRL
HCCCHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MPELEQYFHYRNLDVSSVKELAKRWRPEIMSGLKKNASHLAMDDIRDSISELKYYREYFF
HHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IKN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA