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The map label for this gene is xcpR [H]

Identifier: 50086040

GI number: 50086040

Start: 2952534

End: 2954024

Strand: Reverse

Name: xcpR [H]

Synonym: ACIAD3024

Alternate gene names: 50086040

Gene position: 2954024-2952534 (Counterclockwise)

Preceding gene: 50086043

Following gene: 50086028

Centisome position: 82.09

GC content: 44.27

Gene sequence:

>1491_bases
GTGATGCAAATACTTAAACAAATACAAATTCCATATAGTTTTGCGAAACGCCATGGTGTGTTGTTTCGTTACGAGGGCGA
TCAGGTTTTTATTGTACGCAAAAAAAATACAGCATGGATTGCATTGCAGGAAGCACATCGTTTGTTGGGTAAGTCTGCAC
ATGATCAATTATGTGATGAGCAAGCATTTAATGCATTATTAAGTTCTAGCTATGCAGGAGATCGTGGTGAATCACAACAA
GTCGCTGCCGGACTTGAAGATCATCCTGACTTACTTAGTCTAGCCGATCAGGTTCCTGAAGCAGAAGATTTGATGGATCA
GGAAGATGATGCACCGATTGTTAGACTAATCAATGCCTTACTTTCTGAGGCGATTCGTGTCAGTGCATCAGATATTCATA
TCGAAGCGTTTGAAAAAAAATTATCAGTAAGACTACGTGTTGATGGGCAGCTTCGTGAAATTGTTCAGCCGCGCCGTGAG
CTTGCACCGTTGCTGGTGTCGCGCATCAAGGTGATGGCCAAGCTAGATATTGCAGAAAAACGTATTCCGCAAGATGGTCG
TATTTCATTGCGTCTGGCTGGGCGTGAAGTCGATGTACGTGTTTCCACATTGCCTTCGTCACATGGTGAGCGCGTGGTGA
TGCGTTTGTTGGATAAACAAGCGGGACGCTTGAATATGACTCATTTAGGGTTAATGGCGGAAGACTATGAACGTTTAAAA
TATCTGGTACATCGTCCACATGGAATTATTCTGGTGACGGGGCCTACAGGTTCGGGTAAAACGACAACGCTCTATGCAGC
CTTGTCAGACCTTAACGATCAGACCCGTAATATTTTGACGGCAGAAGATCCGATTGAATATCAGCTCGAAGGGATTGGGC
AGACACAGGTCAATACCAAAGTTGATATGACCTTTGCTCGTGCACTGAAAGCCATGTTACGTCAAGATCCAGATGTGGTC
ATGGTGGGAGAGATTCGTGATCTTGAAACCGCAGAAATTGCCGTGCAAGCCTCACTTACGGGTCACTTGGTTCTATCTAC
CTTACATACCAATACAGCCATTGGCGCCGTGACACGCTTAAAAGATATGGGGATCGAACCATTTCTATTATCAAGTTCTC
TCATTGGTGTGATTGCACAACGGTTGGTGCGTACTTTGTGCCCGCATTGCGTGAGCTGGCGTGAAGCAGATGATTTTGAA
CAGCAGTTATTTCAACATCTTTCTAATGAGCCTCATTTAAAACTACCCGAGCCACAAGGTTGTGAACATTGTTCTTATCT
GGGATTTAGTGGTCGAAGTGCAATCTATGAAATTGTTCCAATTGATGAACATATTCGCAGGATGATACATGGCAATTCGG
CTGAGTACGAGCTTGAGGCGTATGCCCGTCGTCATGCAGGATCAATTCGTGAAGATGGTTTGAAAAAAGTGCTGGCAGGG
AAGACTACACTTGAAGAAGTATTACGTGTAACCAACCAATCAGAAGAATAG

Upstream 100 bases:

>100_bases
CAAGTTTAAAAAATCCTCTGCTCAGTTTGCTTAAAACGGACTTCACGCTGTCATACGCTTAGAGTACACTCAAAAGTCTC
TTTCTGATCATTATAAATGT

Downstream 100 bases:

>100_bases
ATTGATTAAAAAAGCACCTCAAAAGGTGCTCTTTTTACATACAGTATAAAAACTTATGCATCAGTAACAATTTCAAAATC
GACATCAATGTTGTTACGTG

Product: general secretion pathway protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MMQILKQIQIPYSFAKRHGVLFRYEGDQVFIVRKKNTAWIALQEAHRLLGKSAHDQLCDEQAFNALLSSSYAGDRGESQQ
VAAGLEDHPDLLSLADQVPEAEDLMDQEDDAPIVRLINALLSEAIRVSASDIHIEAFEKKLSVRLRVDGQLREIVQPRRE
LAPLLVSRIKVMAKLDIAEKRIPQDGRISLRLAGREVDVRVSTLPSSHGERVVMRLLDKQAGRLNMTHLGLMAEDYERLK
YLVHRPHGIILVTGPTGSGKTTTLYAALSDLNDQTRNILTAEDPIEYQLEGIGQTQVNTKVDMTFARALKAMLRQDPDVV
MVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRLKDMGIEPFLLSSSLIGVIAQRLVRTLCPHCVSWREADDFE
QQLFQHLSNEPHLKLPEPQGCEHCSYLGFSGRSAIYEIVPIDEHIRRMIHGNSAEYELEAYARRHAGSIREDGLKKVLAG
KTTLEEVLRVTNQSEE

Sequences:

>Translated_496_residues
MMQILKQIQIPYSFAKRHGVLFRYEGDQVFIVRKKNTAWIALQEAHRLLGKSAHDQLCDEQAFNALLSSSYAGDRGESQQ
VAAGLEDHPDLLSLADQVPEAEDLMDQEDDAPIVRLINALLSEAIRVSASDIHIEAFEKKLSVRLRVDGQLREIVQPRRE
LAPLLVSRIKVMAKLDIAEKRIPQDGRISLRLAGREVDVRVSTLPSSHGERVVMRLLDKQAGRLNMTHLGLMAEDYERLK
YLVHRPHGIILVTGPTGSGKTTTLYAALSDLNDQTRNILTAEDPIEYQLEGIGQTQVNTKVDMTFARALKAMLRQDPDVV
MVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRLKDMGIEPFLLSSSLIGVIAQRLVRTLCPHCVSWREADDFE
QQLFQHLSNEPHLKLPEPQGCEHCSYLGFSGRSAIYEIVPIDEHIRRMIHGNSAEYELEAYARRHAGSIREDGLKKVLAG
KTTLEEVLRVTNQSEE
>Mature_496_residues
MMQILKQIQIPYSFAKRHGVLFRYEGDQVFIVRKKNTAWIALQEAHRLLGKSAHDQLCDEQAFNALLSSSYAGDRGESQQ
VAAGLEDHPDLLSLADQVPEAEDLMDQEDDAPIVRLINALLSEAIRVSASDIHIEAFEKKLSVRLRVDGQLREIVQPRRE
LAPLLVSRIKVMAKLDIAEKRIPQDGRISLRLAGREVDVRVSTLPSSHGERVVMRLLDKQAGRLNMTHLGLMAEDYERLK
YLVHRPHGIILVTGPTGSGKTTTLYAALSDLNDQTRNILTAEDPIEYQLEGIGQTQVNTKVDMTFARALKAMLRQDPDVV
MVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRLKDMGIEPFLLSSSLIGVIAQRLVRTLCPHCVSWREADDFE
QQLFQHLSNEPHLKLPEPQGCEHCSYLGFSGRSAIYEIVPIDEHIRRMIHGNSAEYELEAYARRHAGSIREDGLKKVLAG
KTTLEEVLRVTNQSEE

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=485, Percent_Identity=54.639175257732, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1786296, Length=387, Percent_Identity=45.4780361757106, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI87082188, Length=169, Percent_Identity=45.5621301775148, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 55524; Mature: 55524

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQILKQIQIPYSFAKRHGVLFRYEGDQVFIVRKKNTAWIALQEAHRLLGKSAHDQLCDE
CHHHHHHHCCCHHHHHHCCEEEEEECCEEEEEEECCCEEEEHHHHHHHHCCCHHHHHHHH
QAFNALLSSSYAGDRGESQQVAAGLEDHPDLLSLADQVPEAEDLMDQEDDAPIVRLINAL
HHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHH
LSEAIRVSASDIHIEAFEKKLSVRLRVDGQLREIVQPRRELAPLLVSRIKVMAKLDIAEK
HHHHHHCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIPQDGRISLRLAGREVDVRVSTLPSSHGERVVMRLLDKQAGRLNMTHLGLMAEDYERLK
HCCCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
YLVHRPHGIILVTGPTGSGKTTTLYAALSDLNDQTRNILTAEDPIEYQLEGIGQTQVNTK
HHHCCCCEEEEEECCCCCCCCEEEEHHHHHCCHHHCCEECCCCCCCHHCCCCCCCCCCCH
VDMTFARALKAMLRQDPDVVMVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHEEEEECCCCEEEEEHHHCCHHHHHHHHH
KDMGIEPFLLSSSLIGVIAQRLVRTLCPHCVSWREADDFEQQLFQHLSNEPHLKLPEPQG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCCC
CEHCSYLGFSGRSAIYEIVPIDEHIRRMIHGNSAEYELEAYARRHAGSIREDGLKKVLAG
CCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHC
KTTLEEVLRVTNQSEE
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMQILKQIQIPYSFAKRHGVLFRYEGDQVFIVRKKNTAWIALQEAHRLLGKSAHDQLCDE
CHHHHHHHCCCHHHHHHCCEEEEEECCEEEEEEECCCEEEEHHHHHHHHCCCHHHHHHHH
QAFNALLSSSYAGDRGESQQVAAGLEDHPDLLSLADQVPEAEDLMDQEDDAPIVRLINAL
HHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHH
LSEAIRVSASDIHIEAFEKKLSVRLRVDGQLREIVQPRRELAPLLVSRIKVMAKLDIAEK
HHHHHHCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIPQDGRISLRLAGREVDVRVSTLPSSHGERVVMRLLDKQAGRLNMTHLGLMAEDYERLK
HCCCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
YLVHRPHGIILVTGPTGSGKTTTLYAALSDLNDQTRNILTAEDPIEYQLEGIGQTQVNTK
HHHCCCCEEEEEECCCCCCCCEEEEHHHHHCCHHHCCEECCCCCCCHHCCCCCCCCCCCH
VDMTFARALKAMLRQDPDVVMVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHEEEEECCCCEEEEEHHHCCHHHHHHHHH
KDMGIEPFLLSSSLIGVIAQRLVRTLCPHCVSWREADDFEQQLFQHLSNEPHLKLPEPQG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCCC
CEHCSYLGFSGRSAIYEIVPIDEHIRRMIHGNSAEYELEAYARRHAGSIREDGLKKVLAG
CCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHC
KTTLEEVLRVTNQSEE
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]