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The map label for this gene is yafV [C]

Identifier: 50086037

GI number: 50086037

Start: 2950613

End: 2951437

Strand: Direct

Name: yafV [C]

Synonym: ACIAD3021

Alternate gene names: 50086037

Gene position: 2950613-2951437 (Clockwise)

Preceding gene: 50086036

Following gene: 50086038

Centisome position: 81.99

GC content: 42.3

Gene sequence:

>825_bases
ATGACTTTACTCTCTGTTGCCCAAATGAACTCGCAAAATGACATTGAAGTAAATTTCGGTGTTGTAGAGCATCTCATTAA
ACAGAGTAAAGCTAAAGATGCGGAGTTGATCGTTTTTCCTGAAAATTTTATCTGTTTTGCTGCAGGTAAACAGCGCGAAA
CCGCTGCACAGTTTGAAGTGATTCAACAGCGTCTTGAAAAACTGGCGCATCAATATAATATCTGGATTATTGCGGGAACT
CTCCCTTGCCCGTTTCGTCCAGATGGATCTATCATTTCTGATGGACGTGTACGTACCGTGAGCCTATGTATTACTCCAGA
AAAGACAGAAGCTCGTTATGACAAAATTCATTTATTTGATGTCCAAGTAGGGGATGCTGTTGGTGGCTATCAGGAATCTA
GGTTTTTTGAGCCTGGGGATCAGATTGTTATTGCCAAAACGCCTTTTGGTAACATTGGCATGATGGTTTGCTATGATTTA
CGCTTTCCTGAATTGGCTTTAAATTTAAGAGCACAAGGTGCAAGAATTTTGACTGCACCAGCAGCTTTTACTTATACAAC
AGGTCAAATGCACTGGCAGCTTTTGCTACAGGCGCGTGCCATGGATAGTCAGTGTGTAGTGCTTGGTGCAGCACAACAAG
GCTGGCATGGTGAAAAGCGTCAAACATGGGGGCATACTGCGGCTACAAATAGTCGCGGTCAGCTCTTAGAGATGGTTCAT
GAAGAAGGTACTGCTTTGATTACTGTAACATTTGATCAAACTGAACAAGATCATGTTCGTGAATCGATGCCACTGATGCA
ACATCGTCGTTTACTTAAGCTTTAA

Upstream 100 bases:

>100_bases
GTTTGAACCGTTGGTGAAACAACTTCAAAAAGAGCAAGATTCACTTGATGAAGCTTGTAGCAAGCAGAATGCTTAATCTG
ATCACGGAATGATTTAGCAC

Downstream 100 bases:

>100_bases
GGCAATCTTGTTGATATAATCCCAATCACTTTTCCCAAGTTTTAACACAAAGCTATACTTGAGAATTGCCAAAAAATCAT
GAGGCCTACATGCAGCAAGA

Product: carbon-nitrogen hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTLLSVAQMNSQNDIEVNFGVVEHLIKQSKAKDAELIVFPENFICFAAGKQRETAAQFEVIQQRLEKLAHQYNIWIIAGT
LPCPFRPDGSIISDGRVRTVSLCITPEKTEARYDKIHLFDVQVGDAVGGYQESRFFEPGDQIVIAKTPFGNIGMMVCYDL
RFPELALNLRAQGARILTAPAAFTYTTGQMHWQLLLQARAMDSQCVVLGAAQQGWHGEKRQTWGHTAATNSRGQLLEMVH
EEGTALITVTFDQTEQDHVRESMPLMQHRRLLKL

Sequences:

>Translated_274_residues
MTLLSVAQMNSQNDIEVNFGVVEHLIKQSKAKDAELIVFPENFICFAAGKQRETAAQFEVIQQRLEKLAHQYNIWIIAGT
LPCPFRPDGSIISDGRVRTVSLCITPEKTEARYDKIHLFDVQVGDAVGGYQESRFFEPGDQIVIAKTPFGNIGMMVCYDL
RFPELALNLRAQGARILTAPAAFTYTTGQMHWQLLLQARAMDSQCVVLGAAQQGWHGEKRQTWGHTAATNSRGQLLEMVH
EEGTALITVTFDQTEQDHVRESMPLMQHRRLLKL
>Mature_273_residues
TLLSVAQMNSQNDIEVNFGVVEHLIKQSKAKDAELIVFPENFICFAAGKQRETAAQFEVIQQRLEKLAHQYNIWIIAGTL
PCPFRPDGSIISDGRVRTVSLCITPEKTEARYDKIHLFDVQVGDAVGGYQESRFFEPGDQIVIAKTPFGNIGMMVCYDLR
FPELALNLRAQGARILTAPAAFTYTTGQMHWQLLLQARAMDSQCVVLGAAQQGWHGEKRQTWGHTAATNSRGQLLEMVHE
EGTALITVTFDQTEQDHVRESMPLMQHRRLLKL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=277, Percent_Identity=33.9350180505415, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI297632350, Length=277, Percent_Identity=33.9350180505415, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI297632348, Length=277, Percent_Identity=33.9350180505415, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI9910460, Length=259, Percent_Identity=29.3436293436293, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI297632346, Length=200, Percent_Identity=32.5, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786412, Length=238, Percent_Identity=26.890756302521, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556280, Length=280, Percent_Identity=34.6428571428571, Blast_Score=165, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322335, Length=297, Percent_Identity=32.996632996633, Blast_Score=143, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6323383, Length=249, Percent_Identity=28.9156626506024, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17933642, Length=276, Percent_Identity=35.8695652173913, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI21355835, Length=256, Percent_Identity=28.515625, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30829; Mature: 30698

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLSVAQMNSQNDIEVNFGVVEHLIKQSKAKDAELIVFPENFICFAAGKQRETAAQFEV
CCEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCHHHHHHHH
IQQRLEKLAHQYNIWIIAGTLPCPFRPDGSIISDGRVRTVSLCITPEKTEARYDKIHLFD
HHHHHHHHHHHEEEEEEEECCCCCCCCCCCEECCCCEEEEEEEECCCCCCCCCCEEEEEE
VQVGDAVGGYQESRFFEPGDQIVIAKTPFGNIGMMVCYDLRFPELALNLRAQGARILTAP
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCHHEEEEECCCCEEEECC
AAFTYTTGQMHWQLLLQARAMDSQCVVLGAAQQGWHGEKRQTWGHTAATNSRGQLLEMVH
CEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EEGTALITVTFDQTEQDHVRESMPLMQHRRLLKL
CCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
TLLSVAQMNSQNDIEVNFGVVEHLIKQSKAKDAELIVFPENFICFAAGKQRETAAQFEV
CEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCHHHHHHHH
IQQRLEKLAHQYNIWIIAGTLPCPFRPDGSIISDGRVRTVSLCITPEKTEARYDKIHLFD
HHHHHHHHHHHEEEEEEEECCCCCCCCCCCEECCCCEEEEEEEECCCCCCCCCCEEEEEE
VQVGDAVGGYQESRFFEPGDQIVIAKTPFGNIGMMVCYDLRFPELALNLRAQGARILTAP
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCHHEEEEECCCCEEEECC
AAFTYTTGQMHWQLLLQARAMDSQCVVLGAAQQGWHGEKRQTWGHTAATNSRGQLLEMVH
CEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EEGTALITVTFDQTEQDHVRESMPLMQHRRLLKL
CCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]