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The map label for this gene is apaH [H]

Identifier: 50086026

GI number: 50086026

Start: 2936032

End: 2936883

Strand: Reverse

Name: apaH [H]

Synonym: ACIAD3008

Alternate gene names: 50086026

Gene position: 2936883-2936032 (Counterclockwise)

Preceding gene: 50086027

Following gene: 50086022

Centisome position: 81.61

GC content: 44.48

Gene sequence:

>852_bases
ATGACCACACGCTACAACTATGTGATTGGTGATGTTCAGGGATGTTTTGAAGCGCTCAAAGCATTGCTGAAAGAAATTCG
GTTTGATCCTGATTTAGACAAACTCTGGTTTGCAGGCGACTTGGTAGCGCGTGGTGAAAACTCAGTCGGTGTACTGCGCT
TTGTCAAGAAACTGGCCGAGCGTGGATGTGCCGAAACGGTTTTGGGTAATCATGATTTAACCTTAATTGCCTGCGCTCGT
GGACACAAAAAAGTAAAAGCCAGAGACAATACTCAACAGGTGATAGATGCGATTGATGGCGATGAGCTAATCGATTGGTT
GCGCCGGCAACCGCTGTGTCTGCTGCCAGATCGTCAAACGATTATTACCCACGCTGGCATTCCATGTATCTGGACGGCTG
AACAGGCATTTCGTCTGGCACGTGAAGTGGAAGCCTATGTCGGACATGATGATTTAAGCCAGCTTGATGAGTTTTTATTA
CAGATGTATGGTGAAGAACCCACGATTTGGTCTGACGATTTGACGGGAATGACACGATTACGTGTGATTACGAATTATTT
GACCAGAATGCGTTTGACCGATATCAATGGGCAGCTTGAGTTTTCATTTAAAGATGAACTTAATGAGCCAATGCCAAAAG
GCTTTTTACCTTGGTTTGATTTTGACAGTCCTGCTGCACACACTCATCAGATCTTTTTTGGACATTGGGCGGCATTGCAA
GGCATGACGATTAATGAACGCATTCAAAATGTAGATGGGGGTTGTGTATGGGGGCGCAACTTAATTGCATATCGTCTTGA
AGACCAGAAAGCTTTTAGTGTCCAAAATCCATTGGCAGACGAATTTTTCTAA

Upstream 100 bases:

>100_bases
ACGATGCTTTTGACAAAGCGGGTATCGATCCGATGGCACGCCCAGAAACCTTAACGCTGGCACAATTTGTGGCATTGTCT
GATCAAATGGTGCCATAAGT

Downstream 100 bases:

>100_bases
ATATTCAACACTCAAAAGCCAAATTTAACAATGATACTTTTGAGTGTTGAGCTTGGTTATTGCAATGATAAAACCAGCGT
TGGTAACCAGAGTGCAGTGA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTTRYNYVIGDVQGCFEALKALLKEIRFDPDLDKLWFAGDLVARGENSVGVLRFVKKLAERGCAETVLGNHDLTLIACAR
GHKKVKARDNTQQVIDAIDGDELIDWLRRQPLCLLPDRQTIITHAGIPCIWTAEQAFRLAREVEAYVGHDDLSQLDEFLL
QMYGEEPTIWSDDLTGMTRLRVITNYLTRMRLTDINGQLEFSFKDELNEPMPKGFLPWFDFDSPAAHTHQIFFGHWAALQ
GMTINERIQNVDGGCVWGRNLIAYRLEDQKAFSVQNPLADEFF

Sequences:

>Translated_283_residues
MTTRYNYVIGDVQGCFEALKALLKEIRFDPDLDKLWFAGDLVARGENSVGVLRFVKKLAERGCAETVLGNHDLTLIACAR
GHKKVKARDNTQQVIDAIDGDELIDWLRRQPLCLLPDRQTIITHAGIPCIWTAEQAFRLAREVEAYVGHDDLSQLDEFLL
QMYGEEPTIWSDDLTGMTRLRVITNYLTRMRLTDINGQLEFSFKDELNEPMPKGFLPWFDFDSPAAHTHQIFFGHWAALQ
GMTINERIQNVDGGCVWGRNLIAYRLEDQKAFSVQNPLADEFF
>Mature_282_residues
TTRYNYVIGDVQGCFEALKALLKEIRFDPDLDKLWFAGDLVARGENSVGVLRFVKKLAERGCAETVLGNHDLTLIACARG
HKKVKARDNTQQVIDAIDGDELIDWLRRQPLCLLPDRQTIITHAGIPCIWTAEQAFRLAREVEAYVGHDDLSQLDEFLLQ
MYGEEPTIWSDDLTGMTRLRVITNYLTRMRLTDINGQLEFSFKDELNEPMPKGFLPWFDFDSPAAHTHQIFFGHWAALQG
MTINERIQNVDGGCVWGRNLIAYRLEDQKAFSVQNPLADEFF

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=268, Percent_Identity=44.0298507462687, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 32382; Mature: 32251

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRYNYVIGDVQGCFEALKALLKEIRFDPDLDKLWFAGDLVARGENSVGVLRFVKKLAE
CCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHCCCCCCHHHHHHHHHHHH
RGCAETVLGNHDLTLIACARGHKKVKARDNTQQVIDAIDGDELIDWLRRQPLCLLPDRQT
CCCHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCEEECCCCCE
IITHAGIPCIWTAEQAFRLAREVEAYVGHDDLSQLDEFLLQMYGEEPTIWSDDLTGMTRL
EEEECCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHH
RVITNYLTRMRLTDINGQLEFSFKDELNEPMPKGFLPWFDFDSPAAHTHQIFFGHWAALQ
HHHHHHHHHHEEEECCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GMTINERIQNVDGGCVWGRNLIAYRLEDQKAFSVQNPLADEFF
CCCHHHHHHCCCCCEEECCCEEEEEECCCHHHHHCCCCHHCCC
>Mature Secondary Structure 
TTRYNYVIGDVQGCFEALKALLKEIRFDPDLDKLWFAGDLVARGENSVGVLRFVKKLAE
CCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHCCCCCCHHHHHHHHHHHH
RGCAETVLGNHDLTLIACARGHKKVKARDNTQQVIDAIDGDELIDWLRRQPLCLLPDRQT
CCCHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCEEECCCCCE
IITHAGIPCIWTAEQAFRLAREVEAYVGHDDLSQLDEFLLQMYGEEPTIWSDDLTGMTRL
EEEECCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHH
RVITNYLTRMRLTDINGQLEFSFKDELNEPMPKGFLPWFDFDSPAAHTHQIFFGHWAALQ
HHHHHHHHHHEEEECCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GMTINERIQNVDGGCVWGRNLIAYRLEDQKAFSVQNPLADEFF
CCCHHHHHHCCCCCEEECCCEEEEEECCCHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA