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The map label for this gene is yqfA [H]

Identifier: 50086017

GI number: 50086017

Start: 2926501

End: 2927226

Strand: Direct

Name: yqfA [H]

Synonym: ACIAD2996

Alternate gene names: 50086017

Gene position: 2926501-2927226 (Clockwise)

Preceding gene: 50086012

Following gene: 50086018

Centisome position: 81.32

GC content: 39.67

Gene sequence:

>726_bases
TTGCCCCTACAGTTTAAAACGACTTACTTTAAAAACAAAATTGAATTACTATACAACTGTATTTTTAATAAAACTTATAA
TCAAATGACACAATATCCGATTCAGGACTACGATCCCTTTGAAGAACAACTCAATGCATGGAGTCATGCGCTTGGAGCAA
TACTTGCTGCAATTGGCGCAATTTTACTCGTGCTCAAGGGCTTTCCTCTTCCGCTTGGGCAATGGATCGGACTCATTGTA
TATGCACTCAGTCTGGTTTTATTATTTAGCAGTTCAACGCTCTACCATTTTGCTAAAACGCCTGAAAAGAGACATTGGTA
TAAGAAACTGGATCACACCGCGATTTATTATCTCATTGCGGGTACATATACGCCCTTTTTGAGTATTGCACTGCCAACTG
CCAAAGCACATTATCTTTTAATTGCGCTTTGGGTCATCGCCTTAATAGGGACCTTATTTAAACTGGTGTTTATTCATCGT
TTTCAAAAAATTTCGCTGCTTGCCTATCTGGTCATGGGCTGGCTGGCGGTACTGGTGATGGATGACATGCGTCAGTTTTT
AAGTTCAGATACACTTTATTTACTGATACTAGGTGGTCTTGCTTATACGGTTGGAGCATTGTTTTATGCCTTAAAAAAGG
TAAGATATACCCATGCTATCTGGCATCTCTTTGTACTTTTAGGCGCAGGATTACACTTCTTGGCCATCTATTGGTACGTG
ATCTAG

Upstream 100 bases:

>100_bases
AAACTGCTGATTTTGAATTGTTTGCTGAGTTAATTCGAGAAACTGTTGTTGTTGTGAAAAATCAGGAGTCTGAACGGACA
TAACGGAAAACCTTGTTTAT

Downstream 100 bases:

>100_bases
TTCATTGTATACAGCCACAGCCACCCTGAATCCGTATTTCAATGACATGAAACTGTCGCTACTTTTTTAAGAAATTACCG
CTTTTTTAAAAAATTACGCT

Product: hemolysin III (HLY-III)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MPLQFKTTYFKNKIELLYNCIFNKTYNQMTQYPIQDYDPFEEQLNAWSHALGAILAAIGAILLVLKGFPLPLGQWIGLIV
YALSLVLLFSSSTLYHFAKTPEKRHWYKKLDHTAIYYLIAGTYTPFLSIALPTAKAHYLLIALWVIALIGTLFKLVFIHR
FQKISLLAYLVMGWLAVLVMDDMRQFLSSDTLYLLILGGLAYTVGALFYALKKVRYTHAIWHLFVLLGAGLHFLAIYWYV
I

Sequences:

>Translated_241_residues
MPLQFKTTYFKNKIELLYNCIFNKTYNQMTQYPIQDYDPFEEQLNAWSHALGAILAAIGAILLVLKGFPLPLGQWIGLIV
YALSLVLLFSSSTLYHFAKTPEKRHWYKKLDHTAIYYLIAGTYTPFLSIALPTAKAHYLLIALWVIALIGTLFKLVFIHR
FQKISLLAYLVMGWLAVLVMDDMRQFLSSDTLYLLILGGLAYTVGALFYALKKVRYTHAIWHLFVLLGAGLHFLAIYWYV
I
>Mature_240_residues
PLQFKTTYFKNKIELLYNCIFNKTYNQMTQYPIQDYDPFEEQLNAWSHALGAILAAIGAILLVLKGFPLPLGQWIGLIVY
ALSLVLLFSSSTLYHFAKTPEKRHWYKKLDHTAIYYLIAGTYTPFLSIALPTAKAHYLLIALWVIALIGTLFKLVFIHRF
QKISLLAYLVMGWLAVLVMDDMRQFLSSDTLYLLILGGLAYTVGALFYALKKVRYTHAIWHLFVLLGAGLHFLAIYWYVI

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=216, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI52630445, Length=214, Percent_Identity=29.9065420560748, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI154759277, Length=240, Percent_Identity=27.5, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1789266, Length=217, Percent_Identity=44.2396313364055, Blast_Score=174, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71996356, Length=226, Percent_Identity=33.1858407079646, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640324, Length=240, Percent_Identity=28.75, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 27743; Mature: 27611

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure 
PLQFKTTYFKNKIELLYNCIFNKTYNQMTQYPIQDYDPFEEQLNAWSHALGAILAAIGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ILLVLKGFPLPLGQWIGLIVYALSLVLLFSSSTLYHFAKTPEKRHWYKKLDHTAIYYLIA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
GTYTPFLSIALPTAKAHYLLIALWVIALIGTLFKLVFIHRFQKISLLAYLVMGWLAVLVM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDMRQFLSSDTLYLLILGGLAYTVGALFYALKKVRYTHAIWHLFVLLGAGLHFLAIYWYV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]