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The map label for this gene is ribB [H]

Identifier: 50085942

GI number: 50085942

Start: 2847313

End: 2847972

Strand: Direct

Name: ribB [H]

Synonym: ACIAD2913

Alternate gene names: 50085942

Gene position: 2847313-2847972 (Clockwise)

Preceding gene: 50085941

Following gene: 50085944

Centisome position: 79.12

GC content: 45.61

Gene sequence:

>660_bases
ATGTCTAGTTTGATTCAAGCTGAAATTTTCTTTTCAGCCCTTTCCCCTGCCGAGCAGCGCATCCAACAAGCTTTGGATGA
CATTCGTCATGGTAAGCCTGTTTTGGTCATGGATGATTTTGATCGTGAAAACGAGGCCGATTTAATTGTGGCTGCCGAAA
CCCTCAATGTCGAGACCATGGCGCGTATGATTCGTGATGGCTCAGGTATTGTTTGCTTCTGTCTAACCGAACAACTGGCA
GATCATTTAGAATTGACACCTATGGTTCAAAACAATTCAAGCCAGTTTCATACAGCATTTACCGTCACCATTGAAGCAGC
GCAGGGCGTAACCACTGGTGTTTCCGCCAAAGACCGTGTAAAGACCATTCATACTGCCATTCAAGATGGTGCTATCGCCA
GTGATTTAAACCGCCCAGGTCATGTGTTTCCTTTACGTGCGCGTGATGGTGGTGTTTTGACTCGTCGAGGGCATACCGAA
GCAACCATTGATCTGGCACGTTTGGCAGGTTTAAAACCCTCGGGTGTGCTATGTGAATTGACCAATCCTGATGGTAGTAT
GGCAACAGGTATTCAAGTGTTGGCTTATGCTCAAACACATCATCTGACCGTAATTACCATTGAAGAACTGGTACAGTATC
GCATCAAGCATAATGTTTAG

Upstream 100 bases:

>100_bases
GACGACGTTTCAACATAAAATAGCTTTGCTATTTTATTGCTACGCCCCCATTTCTCATCAGTCCTGAAATGTTTAACCGT
AATTTACGAGAGCATTTCAT

Downstream 100 bases:

>100_bases
ATTTTGATTTATCCCGAGCAATCGAGTTCGGGATTTTTATTTACTGTTCCATAAACCTAGACCATATAAGGGCCATTTTT
GCTTTACTGCAATATTATTG

Product: 3,4 dihydroxy-2-butanone-4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSSLIQAEIFFSALSPAEQRIQQALDDIRHGKPVLVMDDFDRENEADLIVAAETLNVETMARMIRDGSGIVCFCLTEQLA
DHLELTPMVQNNSSQFHTAFTVTIEAAQGVTTGVSAKDRVKTIHTAIQDGAIASDLNRPGHVFPLRARDGGVLTRRGHTE
ATIDLARLAGLKPSGVLCELTNPDGSMATGIQVLAYAQTHHLTVITIEELVQYRIKHNV

Sequences:

>Translated_219_residues
MSSLIQAEIFFSALSPAEQRIQQALDDIRHGKPVLVMDDFDRENEADLIVAAETLNVETMARMIRDGSGIVCFCLTEQLA
DHLELTPMVQNNSSQFHTAFTVTIEAAQGVTTGVSAKDRVKTIHTAIQDGAIASDLNRPGHVFPLRARDGGVLTRRGHTE
ATIDLARLAGLKPSGVLCELTNPDGSMATGIQVLAYAQTHHLTVITIEELVQYRIKHNV
>Mature_218_residues
SSLIQAEIFFSALSPAEQRIQQALDDIRHGKPVLVMDDFDRENEADLIVAAETLNVETMARMIRDGSGIVCFCLTEQLAD
HLELTPMVQNNSSQFHTAFTVTIEAAQGVTTGVSAKDRVKTIHTAIQDGAIASDLNRPGHVFPLRARDGGVLTRRGHTEA
TIDLARLAGLKPSGVLCELTNPDGSMATGIQVLAYAQTHHLTVITIEELVQYRIKHNV

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=210, Percent_Identity=58.5714285714286, Blast_Score=254, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6320695, Length=205, Percent_Identity=44.390243902439, Blast_Score=168, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23868; Mature: 23736

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLIQAEIFFSALSPAEQRIQQALDDIRHGKPVLVMDDFDRENEADLIVAAETLNVETM
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCHHHH
ARMIRDGSGIVCFCLTEQLADHLELTPMVQNNSSQFHTAFTVTIEAAQGVTTGVSAKDRV
HHHHHCCCCEEEEEEHHHHHHHCEECEEEECCCCCEEEEEEEEEECCCCCCCCCCCHHHH
KTIHTAIQDGAIASDLNRPGHVFPLRARDGGVLTRRGHTEATIDLARLAGLKPSGVLCEL
HHHHHHHHCCCHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCEEEEE
TNPDGSMATGIQVLAYAQTHHLTVITIEELVQYRIKHNV
ECCCCCHHHHEEEEEEECCCCEEEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
SSLIQAEIFFSALSPAEQRIQQALDDIRHGKPVLVMDDFDRENEADLIVAAETLNVETM
CCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCHHHH
ARMIRDGSGIVCFCLTEQLADHLELTPMVQNNSSQFHTAFTVTIEAAQGVTTGVSAKDRV
HHHHHCCCCEEEEEEHHHHHHHCEECEEEECCCCCEEEEEEEEEECCCCCCCCCCCHHHH
KTIHTAIQDGAIASDLNRPGHVFPLRARDGGVLTRRGHTEATIDLARLAGLKPSGVLCEL
HHHHHHHHCCCHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCEEEEE
TNPDGSMATGIQVLAYAQTHHLTVITIEELVQYRIKHNV
ECCCCCHHHHEEEEEEECCCCEEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA