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The map label for this gene is glpD [H]

Identifier: 50085887

GI number: 50085887

Start: 2781978

End: 2783501

Strand: Reverse

Name: glpD [H]

Synonym: ACIAD2844

Alternate gene names: 50085887

Gene position: 2783501-2781978 (Counterclockwise)

Preceding gene: 50085889

Following gene: 50085884

Centisome position: 77.35

GC content: 40.68

Gene sequence:

>1524_bases
ATGGTGATGACAACTTCTGCTTCACTCCCACTATACGATATTGTGGTCGTCGGTGGTGGCATTAATGGTATTGGTATTGC
CAATGATGCTGCTGGAAGGGGCCTATCGGTTTTTTTGTGTGAAAAAGATGATTTTGCTAGCCACACATCTTCTGCCAGCA
GTAAATTAATTCATGGTGGATTGCGATATCTGGAGCATTATGAATTTCGTTTGGTACGAGAGGCTTTAGCAGAGCGTGAA
GTTTTGATGGCAAAAGCACCTCACCTTGTGCGCCCCCTGCGTTTTATTTTGCCTTATCAAGCACATTTACGTTCTGAATG
GCTGATCCGTTCTGGACTATTCCTTTATGATCATTTAGGTAAACGAAAGAAATTAACGGCTTCTAAAAAGATCACTTTCG
ATTCGGCAAGTCCGCTAAAATCTGAAATTTCTAAAGGCTTTGAATATGCCGACTGTACGGTAGATGATGCGCGTTTGGTT
ATTATCAATGCGATTCAAGCGAGAGAAAAAGGTGCAGAACTTGTAACGCATACCGAGTGTTTGTCTGCAGAAATAGTAGA
TGATGTTTGGTTGATTACCTTACAGCATCGGCAAGTACCTTATCAAATTCGTGCCAAAGTGCTCATTAATGCAACTGGTC
CTTGGGTAGAATCTTTTCTCAAGTCTCAACTTAAACAGCATTCACCTTATAAAATTCGGCATATTCAAGGTAGTCATCTT
ATTGTGGCGAAACTTTATGAGGATAACCATGCCTATATATTGCAAAATGAAGATGGACGAATTGTATTTGTCATTCCCTA
TCTGAATGACTTTAGTTTGATTGGCACGACAGATCAGGTTTATTTAGATGATTTGAATCTGGTGAATATCACGCAACAGG
AAATAAGTTATCTCTTGGATGTAGTGAATCGGCACTTTAAAACAGTTCTGACTCGTGCAGATATTATACAGACTTATTCT
GGAGTCAGGCCTTTATGTGATGATGAATCTGATCAGCCGTCTGCTATAACGCGTGATTATACATTGGCGCTCACTATGGT
TTCAGAGGTTGCTCCATTACTTTCGGTATTTGGTGGAAAATTAACAACATATCGCAAACTAGCTGGTTCTGCACTTGAAC
AGTTGAAGTTATTTTTTCCAGATATGACCCCCTCATGGACAGAATACGAGCCTTTACCTGGAGGAGAATACTTTAAGGGG
CAAGATAAATTGGTGAATGCGATTCAGCTACGTATAAAGGGGATTGCTTCTGAACTTGCAAAGCGCTGGGCGACGAGTTA
CGGAACCCGTGTCTGGAAATTATTACAGGGTGTTTATTCGGAAGAAGATTTTGGGATCTACTTTGGACATGGGCTATATC
AGCTTGAAGTAGATTATCTCGTCAAAGTAGAATGGGTCGAGTCAGCAGATGATGTGTTATGGCGTCGCACCAAGTTGGGT
TTTAGATTTAATCAGAATGAGATTTTGGTGTTACAAGACTATTTGATCAGTCTCGTCGTTGGCGAACAAGGTAAGATTGC
ATAA

Upstream 100 bases:

>100_bases
TTATGTAATTTTAAATGGATTCTTGAAATAGATCACTTTCATATTTAATTTTATAAAAAAGTTTGCTAGTTTGAGAACAT
AATAATCATAAAAAAGGGGG

Downstream 100 bases:

>100_bases
ATTAGAATAATTTGTACATTCAAACGGCTTGATTTAGAAAGCTTAAGCCGCTTGAATATGAGAGATTTTTAGATTTCTAC
ACCACCCAAGCTTGTACAAT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MVMTTSASLPLYDIVVVGGGINGIGIANDAAGRGLSVFLCEKDDFASHTSSASSKLIHGGLRYLEHYEFRLVREALAERE
VLMAKAPHLVRPLRFILPYQAHLRSEWLIRSGLFLYDHLGKRKKLTASKKITFDSASPLKSEISKGFEYADCTVDDARLV
IINAIQAREKGAELVTHTECLSAEIVDDVWLITLQHRQVPYQIRAKVLINATGPWVESFLKSQLKQHSPYKIRHIQGSHL
IVAKLYEDNHAYILQNEDGRIVFVIPYLNDFSLIGTTDQVYLDDLNLVNITQQEISYLLDVVNRHFKTVLTRADIIQTYS
GVRPLCDDESDQPSAITRDYTLALTMVSEVAPLLSVFGGKLTTYRKLAGSALEQLKLFFPDMTPSWTEYEPLPGGEYFKG
QDKLVNAIQLRIKGIASELAKRWATSYGTRVWKLLQGVYSEEDFGIYFGHGLYQLEVDYLVKVEWVESADDVLWRRTKLG
FRFNQNEILVLQDYLISLVVGEQGKIA

Sequences:

>Translated_507_residues
MVMTTSASLPLYDIVVVGGGINGIGIANDAAGRGLSVFLCEKDDFASHTSSASSKLIHGGLRYLEHYEFRLVREALAERE
VLMAKAPHLVRPLRFILPYQAHLRSEWLIRSGLFLYDHLGKRKKLTASKKITFDSASPLKSEISKGFEYADCTVDDARLV
IINAIQAREKGAELVTHTECLSAEIVDDVWLITLQHRQVPYQIRAKVLINATGPWVESFLKSQLKQHSPYKIRHIQGSHL
IVAKLYEDNHAYILQNEDGRIVFVIPYLNDFSLIGTTDQVYLDDLNLVNITQQEISYLLDVVNRHFKTVLTRADIIQTYS
GVRPLCDDESDQPSAITRDYTLALTMVSEVAPLLSVFGGKLTTYRKLAGSALEQLKLFFPDMTPSWTEYEPLPGGEYFKG
QDKLVNAIQLRIKGIASELAKRWATSYGTRVWKLLQGVYSEEDFGIYFGHGLYQLEVDYLVKVEWVESADDVLWRRTKLG
FRFNQNEILVLQDYLISLVVGEQGKIA
>Mature_507_residues
MVMTTSASLPLYDIVVVGGGINGIGIANDAAGRGLSVFLCEKDDFASHTSSASSKLIHGGLRYLEHYEFRLVREALAERE
VLMAKAPHLVRPLRFILPYQAHLRSEWLIRSGLFLYDHLGKRKKLTASKKITFDSASPLKSEISKGFEYADCTVDDARLV
IINAIQAREKGAELVTHTECLSAEIVDDVWLITLQHRQVPYQIRAKVLINATGPWVESFLKSQLKQHSPYKIRHIQGSHL
IVAKLYEDNHAYILQNEDGRIVFVIPYLNDFSLIGTTDQVYLDDLNLVNITQQEISYLLDVVNRHFKTVLTRADIIQTYS
GVRPLCDDESDQPSAITRDYTLALTMVSEVAPLLSVFGGKLTTYRKLAGSALEQLKLFFPDMTPSWTEYEPLPGGEYFKG
QDKLVNAIQLRIKGIASELAKRWATSYGTRVWKLLQGVYSEEDFGIYFGHGLYQLEVDYLVKVEWVESADDVLWRRTKLG
FRFNQNEILVLQDYLISLVVGEQGKIA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=508, Percent_Identity=29.7244094488189, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI285002231, Length=508, Percent_Identity=29.7244094488189, Blast_Score=172, Evalue=9e-43,
Organism=Escherichia coli, GI2367226, Length=464, Percent_Identity=51.9396551724138, Blast_Score=473, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI115534726, Length=507, Percent_Identity=30.7692307692308, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17509253, Length=520, Percent_Identity=28.4615384615385, Blast_Score=138, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6322036, Length=537, Percent_Identity=28.1191806331471, Blast_Score=142, Evalue=9e-35,
Organism=Drosophila melanogaster, GI161077125, Length=512, Percent_Identity=28.515625, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24653942, Length=512, Percent_Identity=28.515625, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24653944, Length=512, Percent_Identity=28.515625, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI20130025, Length=512, Percent_Identity=28.515625, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24586295, Length=513, Percent_Identity=28.4600389863548, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19921278, Length=524, Percent_Identity=22.3282442748092, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57356; Mature: 57356

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMTTSASLPLYDIVVVGGGINGIGIANDAAGRGLSVFLCEKDDFASHTSSASSKLIHGG
CEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LRYLEHYEFRLVREALAEREVLMAKAPHLVRPLRFILPYQAHLRSEWLIRSGLFLYDHLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCC
KRKKLTASKKITFDSASPLKSEISKGFEYADCTVDDARLVIINAIQAREKGAELVTHTEC
CCCCCCCCCEEEECCCCCHHHHHHCCCCEECCCCCCCEEEEEEEHHHHHCCCHHHHHHHH
LSAEIVDDVWLITLQHRQVPYQIRAKVLINATGPWVESFLKSQLKQHSPYKIRHIQGSHL
HHHHHHCCEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCEE
IVAKLYEDNHAYILQNEDGRIVFVIPYLNDFSLIGTTDQVYLDDLNLVNITQQEISYLLD
EEEEEEECCCEEEEECCCCCEEEEEECCCCCEEECCCCEEEECCCCEEEECHHHHHHHHH
VVNRHFKTVLTRADIIQTYSGVRPLCDDESDQPSAITRDYTLALTMVSEVAPLLSVFGGK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LTTYRKLAGSALEQLKLFFPDMTPSWTEYEPLPGGEYFKGQDKLVNAIQLRIKGIASELA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KRWATSYGTRVWKLLQGVYSEEDFGIYFGHGLYQLEVDYLVKVEWVESADDVLWRRTKLG
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEEEEEECCCHHHHHHHHHHCC
FRFNQNEILVLQDYLISLVVGEQGKIA
EEECCCCEEEEHHHHHHEEECCCCCCC
>Mature Secondary Structure
MVMTTSASLPLYDIVVVGGGINGIGIANDAAGRGLSVFLCEKDDFASHTSSASSKLIHGG
CEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LRYLEHYEFRLVREALAEREVLMAKAPHLVRPLRFILPYQAHLRSEWLIRSGLFLYDHLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCC
KRKKLTASKKITFDSASPLKSEISKGFEYADCTVDDARLVIINAIQAREKGAELVTHTEC
CCCCCCCCCEEEECCCCCHHHHHHCCCCEECCCCCCCEEEEEEEHHHHHCCCHHHHHHHH
LSAEIVDDVWLITLQHRQVPYQIRAKVLINATGPWVESFLKSQLKQHSPYKIRHIQGSHL
HHHHHHCCEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCEE
IVAKLYEDNHAYILQNEDGRIVFVIPYLNDFSLIGTTDQVYLDDLNLVNITQQEISYLLD
EEEEEEECCCEEEEECCCCCEEEEEECCCCCEEECCCCEEEECCCCEEEECHHHHHHHHH
VVNRHFKTVLTRADIIQTYSGVRPLCDDESDQPSAITRDYTLALTMVSEVAPLLSVFGGK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LTTYRKLAGSALEQLKLFFPDMTPSWTEYEPLPGGEYFKGQDKLVNAIQLRIKGIASELA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KRWATSYGTRVWKLLQGVYSEEDFGIYFGHGLYQLEVDYLVKVEWVESADDVLWRRTKLG
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEEEEEECCCHHHHHHHHHHCC
FRFNQNEILVLQDYLISLVVGEQGKIA
EEECCCCEEEEHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]