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The map label for this gene is kipR [H]

Identifier: 50085863

GI number: 50085863

Start: 2754416

End: 2755177

Strand: Reverse

Name: kipR [H]

Synonym: ACIAD2817

Alternate gene names: 50085863

Gene position: 2755177-2754416 (Counterclockwise)

Preceding gene: 50085864

Following gene: 50085862

Centisome position: 76.56

GC content: 37.14

Gene sequence:

>762_bases
ATGACAAATTTATCAAATGAAGACTTAGGCTCAGATAGCAAGCAGAACTCAGGTGTTGCTGCCGTAGATAGAGCTTTACT
CATCTTATCTTCATTCGATATTGAGAATCCAAGCCTATCTCTAGCTGAAATTTCAAGACGTACAAAACTTTATAAAAGTA
CTATCCTCAGACTTCTTAATTCATTAGAACGACATGGTTATATCCGTAAAAATACTGATGGGCTCTATTCTTTAAGTATT
ATGCCTCTTAAGCTTGCTAGAATTTATCAAAACTCCTTCAATTTAAAAGATATTATTTATCCTATCCTTGAAAAGATTTC
GGAGGAAACAGGAGAAACTTCATCTTTCTACATATTAGACAATGAGAGCCGTGTTGTCTTATTCCGTATAGAGCCAGTTC
GATCTGTCAAGGTTTCTATCTCTGAAGGTGATGTTTTCCCTGTGAACGTGGGCGCTTCAGGGAAAATACTATCTGCATTT
TCAAAACAGCAAATAGAAGCTAGATTGGAACCAATAAAAGAGAATTATTGGGCAAGTTCTTTTGGAGAACGTGATCCTGA
AACGTCATCTCTTTCCGTACCTGTTCTAGATGGGAGCCAATATTTACAAGGTGCCTTAACCATTTCAGGGCCTTCTGAAC
GACTCACTAGCGAAACTATTAACGGATATATTCCGCATTTAATGAAGTACGGCATTACAATTTCAAAGCAATTAGGTGCT
AATACGATGCTCTATGAAGCAGCATACGCAAATCAACTATAG

Upstream 100 bases:

>100_bases
TTTATTACTATAAAACTGAAACAAGAATCTATTTGTCTATTTAAATTAAAGTTATACTGCTGCTTGTTGATTTTATCGGA
AGTTTTTAGGTTTCTTTTCT

Downstream 100 bases:

>100_bases
TCTGTAAAATAAAATTTCGAAGATTTTATAAAAGGCTTGTCAAAGTAAGGGACTATATTTAACTTTTTAAGCCATTCTAA
AATGCAGAAGGTCTGCGTCG

Product: transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTNLSNEDLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTDGLYSLSI
MPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPVRSVKVSISEGDVFPVNVGASGKILSAF
SKQQIEARLEPIKENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIPHLMKYGITISKQLGA
NTMLYEAAYANQL

Sequences:

>Translated_253_residues
MTNLSNEDLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTDGLYSLSI
MPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPVRSVKVSISEGDVFPVNVGASGKILSAF
SKQQIEARLEPIKENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIPHLMKYGITISKQLGA
NTMLYEAAYANQL
>Mature_252_residues
TNLSNEDLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTDGLYSLSIM
PLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPVRSVKVSISEGDVFPVNVGASGKILSAFS
KQQIEARLEPIKENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIPHLMKYGITISKQLGAN
TMLYEAAYANQL

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=246, Percent_Identity=25.2032520325203, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082359, Length=232, Percent_Identity=23.2758620689655, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788131, Length=265, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28098; Mature: 27967

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLSNEDLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLERHGYIRKNTDGLYSLSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILD
HHHHCCCEEECCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
NESRVVLFRIEPVRSVKVSISEGDVFPVNVGASGKILSAFSKQQIEARLEPIKENYWASS
CCCEEEEEEECCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
FGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIPHLMKYGITISKQLGA
CCCCCCCCCCEEEEEECCHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEHHCCC
NTMLYEAAYANQL
CCEEEHHHHHCCC
>Mature Secondary Structure 
TNLSNEDLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLERHGYIRKNTDGLYSLSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILD
HHHHCCCEEECCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
NESRVVLFRIEPVRSVKVSISEGDVFPVNVGASGKILSAFSKQQIEARLEPIKENYWASS
CCCEEEEEEECCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
FGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIPHLMKYGITISKQLGA
CCCCCCCCCCEEEEEECCHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEHHCCC
NTMLYEAAYANQL
CCEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]