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The map label for this gene is ltrA [H]

Identifier: 50085801

GI number: 50085801

Start: 2685080

End: 2686036

Strand: Reverse

Name: ltrA [H]

Synonym: ACIAD2742

Alternate gene names: 50085801

Gene position: 2686036-2685080 (Counterclockwise)

Preceding gene: 50085804

Following gene: 50085800

Centisome position: 74.64

GC content: 42.63

Gene sequence:

>957_bases
ATGAGCACAAATCAAGGTATTCATCTTTTACAGGAAATGGCGATTTTTGTGAAAGTTGTCGAAACAGGTAGTTTTTCAGA
AACATCACGTCAGATGGGAAGCACACCATCGGCAGTGAGCCGAGCCATTTCCAGACTCGAAAAAGCACTTGGAACACGGT
TATTACAACGTACAACCCGAAAATTACGTTTAAGCGAAAGTGGACAGCAGATTTATGAAAACTGTCTGGATATGGTCAAT
GCTGCACAGGCAGTTATGCAAAGTTCAGGGCAGTTTCATGCAGAACCTCAAGGTACCGTGCGGATGAGTGTGCCTAAAGC
GGTTGGGCATTTTATGATTCATCCTCACATGCCTGAGTTTTTGCAGCGTTATCCTAAAATTGATGTACAGATGTTATTAG
AAGATCGTTATGTTGATTTTATTGATGATGGCGTTGATTTGGCGATCAGGATTACAGATCAGCCTCCAGGCGGTTTAATG
GGGAGACGGCTAATTGAAATAGGGCATTTGCTCTGTGCTACGCCTGAATATCTTGCTATGCATGGAACTCCAGAGCATCC
ACATGATTTAAAACAACATGCGTGTATCTATTTAGGTGAGCAACCAAGTGATTCAAAATGGAAATTCCAGCAGGGCAGTA
AAAGCATTACAGTTGCTGTGAAAGGACGCTATTCGGCCAATCATACTGGAATCCGTCTGGATGCTGCACTCAAGCATCTT
GGTATTGCCAGTTTGCCATATTTCGTGGCTCGTCATGCGCTTGAGTCTGGAGATTTGATTCAGGTTTTGCCAGACTGGTA
CTTCAAAACTTATTATAGTGGCGATGCATGGTTGCTTTATCCACCCACTCGGCATTTACCTCCTAAGCTCAGTGTATTGA
TTCAATTTTTGGCAGAAAAACTGGCACAGGAGCCAAATTTATCATCGTTTTTTCAGGGAGATAAAAGCAGATATTAA

Upstream 100 bases:

>100_bases
TGAGCAAGCATCGATTCAGCCCTAACAATAATTCTTCCAATAGTTTAAGAAAGTAATGCAATGGTGATAATCTAGTAAAA
AATCAAATCATTTTTGCGTC

Downstream 100 bases:

>100_bases
ATGACGATCTTAATGATAATACCGATACAAAAATACGCCGATAACAACATTATTTCTTGATGAAAGATCGTGATAATTAA
ACTTTCTATTTTAGACAGTA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSTNQGIHLLQEMAIFVKVVETGSFSETSRQMGSTPSAVSRAISRLEKALGTRLLQRTTRKLRLSESGQQIYENCLDMVN
AAQAVMQSSGQFHAEPQGTVRMSVPKAVGHFMIHPHMPEFLQRYPKIDVQMLLEDRYVDFIDDGVDLAIRITDQPPGGLM
GRRLIEIGHLLCATPEYLAMHGTPEHPHDLKQHACIYLGEQPSDSKWKFQQGSKSITVAVKGRYSANHTGIRLDAALKHL
GIASLPYFVARHALESGDLIQVLPDWYFKTYYSGDAWLLYPPTRHLPPKLSVLIQFLAEKLAQEPNLSSFFQGDKSRY

Sequences:

>Translated_318_residues
MSTNQGIHLLQEMAIFVKVVETGSFSETSRQMGSTPSAVSRAISRLEKALGTRLLQRTTRKLRLSESGQQIYENCLDMVN
AAQAVMQSSGQFHAEPQGTVRMSVPKAVGHFMIHPHMPEFLQRYPKIDVQMLLEDRYVDFIDDGVDLAIRITDQPPGGLM
GRRLIEIGHLLCATPEYLAMHGTPEHPHDLKQHACIYLGEQPSDSKWKFQQGSKSITVAVKGRYSANHTGIRLDAALKHL
GIASLPYFVARHALESGDLIQVLPDWYFKTYYSGDAWLLYPPTRHLPPKLSVLIQFLAEKLAQEPNLSSFFQGDKSRY
>Mature_317_residues
STNQGIHLLQEMAIFVKVVETGSFSETSRQMGSTPSAVSRAISRLEKALGTRLLQRTTRKLRLSESGQQIYENCLDMVNA
AQAVMQSSGQFHAEPQGTVRMSVPKAVGHFMIHPHMPEFLQRYPKIDVQMLLEDRYVDFIDDGVDLAIRITDQPPGGLMG
RRLIEIGHLLCATPEYLAMHGTPEHPHDLKQHACIYLGEQPSDSKWKFQQGSKSITVAVKGRYSANHTGIRLDAALKHLG
IASLPYFVARHALESGDLIQVLPDWYFKTYYSGDAWLLYPPTRHLPPKLSVLIQFLAEKLAQEPNLSSFFQGDKSRY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=32.9896907216495, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI87081978, Length=309, Percent_Identity=31.0679611650485, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=31.740614334471, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=29.8305084745763, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=28.6195286195286, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787128, Length=280, Percent_Identity=30, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787589, Length=301, Percent_Identity=26.9102990033223, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788706, Length=308, Percent_Identity=24.6753246753247, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788748, Length=178, Percent_Identity=30.8988764044944, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789173, Length=253, Percent_Identity=26.8774703557312, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786448, Length=291, Percent_Identity=25.4295532646048, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082132, Length=297, Percent_Identity=23.2323232323232, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35760; Mature: 35628

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNQGIHLLQEMAIFVKVVETGSFSETSRQMGSTPSAVSRAISRLEKALGTRLLQRTTR
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLRLSESGQQIYENCLDMVNAAQAVMQSSGQFHAEPQGTVRMSVPKAVGHFMIHPHMPEF
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECHHHHHHEEECCCCHHH
LQRYPKIDVQMLLEDRYVDFIDDGVDLAIRITDQPPGGLMGRRLIEIGHLLCATPEYLAM
HHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHEE
HGTPEHPHDLKQHACIYLGEQPSDSKWKFQQGSKSITVAVKGRYSANHTGIRLDAALKHL
CCCCCCCHHHHHCEEEEECCCCCCCCCEECCCCCEEEEEEECCCCCCCCCEEHHHHHHHC
GIASLPYFVARHALESGDLIQVLPDWYFKTYYSGDAWLLYPPTRHLPPKLSVLIQFLAEK
CHHHHHHHHHHHHCCCCCEEEECHHHHHHEEECCCEEEECCCCCCCCHHHHHHHHHHHHH
LAQEPNLSSFFQGDKSRY
HHCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
STNQGIHLLQEMAIFVKVVETGSFSETSRQMGSTPSAVSRAISRLEKALGTRLLQRTTR
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLRLSESGQQIYENCLDMVNAAQAVMQSSGQFHAEPQGTVRMSVPKAVGHFMIHPHMPEF
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECHHHHHHEEECCCCHHH
LQRYPKIDVQMLLEDRYVDFIDDGVDLAIRITDQPPGGLMGRRLIEIGHLLCATPEYLAM
HHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHEE
HGTPEHPHDLKQHACIYLGEQPSDSKWKFQQGSKSITVAVKGRYSANHTGIRLDAALKHL
CCCCCCCHHHHHCEEEEECCCCCCCCCEECCCCCEEEEEEECCCCCCCCCEEHHHHHHHC
GIASLPYFVARHALESGDLIQVLPDWYFKTYYSGDAWLLYPPTRHLPPKLSVLIQFLAEK
CHHHHHHHHHHHHCCCCCEEEECHHHHHHEEECCCEEEECCCCCCCCHHHHHHHHHHHHH
LAQEPNLSSFFQGDKSRY
HHCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]