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The map label for this gene is yhcS [C]

Identifier: 50085788

GI number: 50085788

Start: 2672578

End: 2673465

Strand: Direct

Name: yhcS [C]

Synonym: ACIAD2727

Alternate gene names: 50085788

Gene position: 2672578-2673465 (Clockwise)

Preceding gene: 50085779

Following gene: 50085791

Centisome position: 74.27

GC content: 35.25

Gene sequence:

>888_bases
ATGGAATTTCTTAACGATATGGCATTGTTCGTAGAAGTTTGCAAAGTGATGAGTTTTAGAAAAGCTGCTGATAAGCTGAA
TATGCCTAGTTCAACACTATCAAGAAGAATTGGTCATTTAGAAAAAGAAATAGGTTTACGATTGCTCCATCGAACAACAA
GAAAAGTAGAGCTAACAGAAGCAGGCCAAGTTTATTTTGAGCGTTGTAAACCAATTGTCAGCGAAGCACTATTGGCTCAT
GAACAGCTTGGAGAAATGTTATCTAAACCCAGTGGGTTACTACGTATTTCTTTACCGGTTGATTTTGGAGTAATGATTTT
GGCTCCACTACTCACAGAATTTGCAGAACTTTATCCTGAAATTAACTTTGAAATTGATTTGACCCCCAAACTGGTTGATC
TAGTTAAACAGAATATTGATGTAGCTATTCGAATGGGAAACCCACCAGATTCAAATTTAATCGGCCACAAATTAATGCAA
TTTCGAGGACAACTTTATGCATCCGCAGATTATTTAGAAAAAAATGGACATCCAAATCATCCAAGTGATTTAGTCCATCA
TCAATGTCTGAGTTTTCCAAACAATTTACTGTGGAAACTGAATCATAAAAATGAGACTGTAGATGTTAAGATTACTGGAA
GATTCATGCTAAATAGTGTTGGTATGATGCGAAAATTATCAATTCTCGGCCAAGGAATTATTTTTACACCTCGTGCGATA
GTTTATGATGATATAAATAAAGGGCTATTAGTACCCATTCTTACTGAATGGCAAGGCGATTTTCTACCTGCTTATGCAAT
GACAGAAACCCGTTTACTTCCTGCAAAAGTTCGAGTTTTTATTGATTTTTTACGAGAAAAATTAATGAATTTTACGACTC
ACTCTTAG

Upstream 100 bases:

>100_bases
AAGTTAAAGATGCCAGTAAGTAGAAATAGTATTAACGAGTCAGCCTTTGGGATAAATATGGTAAAATGGAACTTATTAAT
CCATTATTGGGATAATCTGG

Downstream 100 bases:

>100_bases
AGAGTCCATATTGTGACCGTCTATAAAATGAAAAAGCCATTTAGAATGAATGAAAACTTTACATATCCATATTAATGACG
ACCCCAAAAAATATAAAATA

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQVYFERCKPIVSEALLAH
EQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQ
FRGQLYASADYLEKNGHPNHPSDLVHHQCLSFPNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAI
VYDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKVRVFIDFLREKLMNFTTHS

Sequences:

>Translated_295_residues
MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQVYFERCKPIVSEALLAH
EQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQ
FRGQLYASADYLEKNGHPNHPSDLVHHQCLSFPNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAI
VYDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKVRVFIDFLREKLMNFTTHS
>Mature_295_residues
MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQVYFERCKPIVSEALLAH
EQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQ
FRGQLYASADYLEKNGHPNHPSDLVHHQCLSFPNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAI
VYDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKVRVFIDFLREKLMNFTTHS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=32.7586206896552, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=31.7241379310345, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=32.4232081911263, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=27.8745644599303, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=30, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=28.8732394366197, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787589, Length=294, Percent_Identity=29.5918367346939, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1789173, Length=264, Percent_Identity=28.4090909090909, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790011, Length=287, Percent_Identity=25.7839721254355, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788706, Length=183, Percent_Identity=30.6010928961749, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=137, Percent_Identity=27.007299270073, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788748, Length=153, Percent_Identity=28.1045751633987, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=23.3333333333333, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33612; Mature: 33612

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH
CCEEEECCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSDLVHHQCLSFPNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAI
HHHHHHHHHHCCCCHHEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCEEECCCEE
VYDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKVRVFIDFLREKLMNFTTHS
EEECCCCCEEEEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH
CCEEEECCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSDLVHHQCLSFPNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAI
HHHHHHHHHHCCCCHHEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCEEECCCEE
VYDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKVRVFIDFLREKLMNFTTHS
EEECCCCCEEEEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]