BacMap

Definition	Acinetobacter sp. ADP1 chromosome, complete genome.
Accession	NC_005966
Length	3,598,621

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The map label for this gene is yxbG [H]

Identifier: 50085743

GI number: 50085743

Start: 2630795

End: 2631646

Strand: Reverse

Name: yxbG [H]

Synonym: ACIAD2676

Alternate gene names: 50085743

Gene position: 2631646-2630795 (Counterclockwise)

Preceding gene: 50085744

Following gene: 50085742

Centisome position: 73.13

GC content: 46.83

Gene sequence:

>852_bases
TTGGTCGAGCAGCGAAGGCAAATCGATTTAACGATTGAAAGGAATCATCAGGAGCAAGAGATGAATATTGAATTGAATCA
AAAAATTGCCGTGGTGAGTGGTGGTGCGACACTGATTGGTCAGGCAGTGGTACAAGCATTGGTCAATGCGGGTGCAAAAG
TTGTGATTCTGGATATTGCCGAGCAGGGGCAACAGGTCGCTGATGCCATGAACGGGCAGGCACAATTTATTCAAACCGAT
TTAAGCAGTGATGTCGCGATTGCCCGTGCAGTCAAGACTATTCATGAAACATTTGGAAAAGTCGATTACTTGGTCAATCT
GGCCTGTACCTATCTGGATGATGGTTTTAAGTCTTCACGTGGCGATTGGTTACAGGCACTGGATGTCAATCTGGTGTCGG
CGGTCGAATTGACCCGTGCTTTTTATCAAGATTTAAAAATTAATCAGGGGGCGATTGTGAATTTCACATCCATCTCTGCC
AAATTTGCACAAACAGGCCGTTGGTTGTATCCCGTTTCAAAAGCGGCAATGCGCCAATTGACTCAATCCATGGCGATGGA
TTTTGCAGCTGATGGTATCCGTGTGAATTCGGTATCGCCAGGCTGGACATGGTCACGTGTCATTGCAGAAGTGAGTGGCA
ATAATCGAGCTAAGGCAGACGCTGTGGCAGCTGATTATCACTTGCTTGGACGCTTGGGCAATCCTGAAGAAGTCGCCAAT
GTTGTTTTATTTTTACTTTCACCCGCCGCAAGTTTTGTGACAGGTGCTGATTATGCCGTCGATGGAGGCTACTCCGTCAT
GGGGCCAGAAGGGAATCAACCTGCTATTCCACGCTTAAGTAATGAAGCGTAA

Upstream 100 bases:

>100_bases
AGATCGGATTGTTAAATCCTCAAGGTCTACCTGTTGCTGGTATTGAAACTGCCCAAAAACTGCTGGATGAGGAAATGCCA
TCCAATACTTTAATGCCGTC

Downstream 100 bases:

>100_bases
TAGCAAATCAATGTTTAAACCTTAAATGATTTAAAAAAATGTGGGAGAACCATGATGCGTCGTATAGCAATTGTTGGAGC
GGGTCAGTCTGGATTACAGC

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MVEQRRQIDLTIERNHQEQEMNIELNQKIAVVSGGATLIGQAVVQALVNAGAKVVILDIAEQGQQVADAMNGQAQFIQTD
LSSDVAIARAVKTIHETFGKVDYLVNLACTYLDDGFKSSRGDWLQALDVNLVSAVELTRAFYQDLKINQGAIVNFTSISA
KFAQTGRWLYPVSKAAMRQLTQSMAMDFAADGIRVNSVSPGWTWSRVIAEVSGNNRAKADAVAADYHLLGRLGNPEEVAN
VVLFLLSPAASFVTGADYAVDGGYSVMGPEGNQPAIPRLSNEA

Sequences:

>Translated_283_residues
MVEQRRQIDLTIERNHQEQEMNIELNQKIAVVSGGATLIGQAVVQALVNAGAKVVILDIAEQGQQVADAMNGQAQFIQTD
LSSDVAIARAVKTIHETFGKVDYLVNLACTYLDDGFKSSRGDWLQALDVNLVSAVELTRAFYQDLKINQGAIVNFTSISA
KFAQTGRWLYPVSKAAMRQLTQSMAMDFAADGIRVNSVSPGWTWSRVIAEVSGNNRAKADAVAADYHLLGRLGNPEEVAN
VVLFLLSPAASFVTGADYAVDGGYSVMGPEGNQPAIPRLSNEA
>Mature_283_residues
MVEQRRQIDLTIERNHQEQEMNIELNQKIAVVSGGATLIGQAVVQALVNAGAKVVILDIAEQGQQVADAMNGQAQFIQTD
LSSDVAIARAVKTIHETFGKVDYLVNLACTYLDDGFKSSRGDWLQALDVNLVSAVELTRAFYQDLKINQGAIVNFTSISA
KFAQTGRWLYPVSKAAMRQLTQSMAMDFAADGIRVNSVSPGWTWSRVIAEVSGNNRAKADAVAADYHLLGRLGNPEEVAN
VVLFLLSPAASFVTGADYAVDGGYSVMGPEGNQPAIPRLSNEA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=34.2412451361868, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=31.4159292035398, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=30.5882352941176, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=27.843137254902, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4758504, Length=249, Percent_Identity=28.5140562248996, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=31.2, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=27.0491803278689, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=29.6, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=29.2, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=30, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI83715985, Length=249, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=27.363184079602, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=28.125, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=28.5123966942149, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=31.5789473684211, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=28.3524904214559, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=29.8449612403101, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=29.7619047619048, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=27.3469387755102, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=29.0836653386454, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=29.8850574712644, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=207, Percent_Identity=28.5024154589372, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=25.6198347107438, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787820, Length=177, Percent_Identity=25.9887005649718, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=28.1632653061224, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=33.203125, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=199, Percent_Identity=35.1758793969849, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=29.9610894941634, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=30.4182509505703, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538480, Length=279, Percent_Identity=30.1075268817204, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=29.4776119402985, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.7709923664122, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=277, Percent_Identity=27.4368231046931, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=30.4878048780488, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=28.6259541984733, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=29.6153846153846, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=31.1111111111111, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=28.5185185185185, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=235, Percent_Identity=27.6595744680851, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.1368821292776, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=30.1960784313725, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=29.5275590551181, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=191, Percent_Identity=32.9842931937173, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=27.5735294117647, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=27.4131274131274, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=212, Percent_Identity=30.6603773584906, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=29.5275590551181, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=27.0916334661355, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=195, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=28.0898876404494, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=119, Percent_Identity=36.1344537815126, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=26.8482490272374, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322861, Length=239, Percent_Identity=25.5230125523013, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=32.9501915708812, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=31.3008130081301, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=31.1023622047244, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.7086614173228, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=31.7647058823529, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=32.5396825396825, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737361, Length=233, Percent_Identity=26.6094420600858, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=30.7086614173228, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 30518; Mature: 30518

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEQRRQIDLTIERNHQEQEMNIELNQKIAVVSGGATLIGQAVVQALVNAGAKVVILDIA
CCCCCCEEEEEEECCCCCHHCCEEECCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECH
EQGQQVADAMNGQAQFIQTDLSSDVAIARAVKTIHETFGKVDYLVNLACTYLDDGFKSSR
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDWLQALDVNLVSAVELTRAFYQDLKINQGAIVNFTSISAKFAQTGRWLYPVSKAAMRQL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCEEEHHHHHHHHHH
TQSMAMDFAADGIRVNSVSPGWTWSRVIAEVSGNNRAKADAVAADYHLLGRLGNPEEVAN
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VVLFLLSPAASFVTGADYAVDGGYSVMGPEGNQPAIPRLSNEA
HHHHHHCCHHHHHCCCCEEECCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVEQRRQIDLTIERNHQEQEMNIELNQKIAVVSGGATLIGQAVVQALVNAGAKVVILDIA
CCCCCCEEEEEEECCCCCHHCCEEECCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECH
EQGQQVADAMNGQAQFIQTDLSSDVAIARAVKTIHETFGKVDYLVNLACTYLDDGFKSSR
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDWLQALDVNLVSAVELTRAFYQDLKINQGAIVNFTSISAKFAQTGRWLYPVSKAAMRQL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCEEEHHHHHHHHHH
TQSMAMDFAADGIRVNSVSPGWTWSRVIAEVSGNNRAKADAVAADYHLLGRLGNPEEVAN
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VVLFLLSPAASFVTGADYAVDGGYSVMGPEGNQPAIPRLSNEA
HHHHHHCCHHHHHCCCCEEECCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377 [H]