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The map label for this gene is lolC [H]

Identifier: 50085711

GI number: 50085711

Start: 2595293

End: 2596528

Strand: Reverse

Name: lolC [H]

Synonym: ACIAD2641

Alternate gene names: 50085711

Gene position: 2596528-2595293 (Counterclockwise)

Preceding gene: 50085712

Following gene: 50085710

Centisome position: 72.15

GC content: 41.1

Gene sequence:

>1236_bases
ATGTTTAAACCAATCTCGCTGTATATAGGGTTGCGATATACTCGTGCTCGGCGTAGTAATCACTTTATTTCTTTTATTGC
CTTAGTTTCGATGATTGGTCTGACCTTAGGTGTTGCGGTATTAATCACCGTTTTGTCTGTGATGAATGGTTTTGACCGTG
AATTGAAAAATCGTGTGCTGGGAATGGTTCCACAGGCCACAATTTCATCAACACAGATATTGACCAATTGGCCAGAGCTT
GCAAAAAAAGTTGAAGGACACAAGCATGTGGTTGGTGTTGCACCATTTACACAACTGCAAGGGATGCTGACAGCACAAGG
TCAGGTTGCAGGCATTATGGTCAGCGGAATCGACCCGCAGTATGAAAAAAAGGTATCGATTATCCAGAATCATATGGTTG
CGGGTAGTATTGATAATCTTAAGAAAGGTGAGTTTGGGATTGTACTGGGCAAACAGATGACAGATGCATTGGGGCTTGGC
CTCAATGATAATGTGACTTTGGTTTTACCTGAGGCAACACCTTCTCCTGCTGGAGTAGTTCCTCGTTTTAAACGTTTTAA
AATTGTTGGGATTTTTAGCATTGGTGCAGAAGTTGACTCAATGATGGGTTATATCGCTTTAAACGATGCTTCAACTTTAC
TACGTTTACCAGATGGCGCTCAGGGAATTCGTTTAAAACTGGATGATATTTTTGCTGCTCCTCAAGTGGCAGATGATATT
GTTAGAACCTTACCACCTAATTTTTATGCGTCTAACTGGACCTATACACACGGTAACCTATTTAGTGCGATTCAGATGGA
AAAAGCCATGGTGAGCTTGCTTCTATTTCTGATTGTACTGGTGGCTGCATTTAATATCGTTTCATCTTTAGTGATGGTCG
TCACAGACAAAAAATCTGATATTGCGATTTTGAGAACGCTGGGTGCTTCGCCAGCAACTATTACTAAAATTTTTATGGTG
CAGGGCACAGTGATTGGTGTGATTGGTACGGTGGCTGGTGCGGTTCTTGGGGTTATTTTTGCATCGAGTGTGAGTAATAT
TATCGACTGGGTAAATACCGCTTTAGGTCTTCATTTATTTGATGCTTATTTTATTAATTATTTGCCATCTTACTTGCGCT
GGCAAGATGTGGTCCTGATTGTGTCGGTTTCTTTATTGTTAAGTTTCCTTGCCACTATTTACCCAGCATTACGTGCAGCT
AAGATTCAACCAGCAGAGGCATTACGTTATGAGTAA

Upstream 100 bases:

>100_bases
ACCCAGATTCTTTTGGTGTATCAATACGTGTTAGATGCTGATCGCAGTATTGAGTGCAATACTGTATTTCCGATAATGAA
ATGACCTTGGACTAATTGGT

Downstream 100 bases:

>100_bases
AATTGTGCTGGAAGCAAAAGATGTTTACAAACATTTTACTGATGGTAAATCGACAGTAGAAGTGATCAAGGGATTATCAC
TCAAAATTGCTGCGGGCGAA

Product: outer membrane lipoproteins ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MFKPISLYIGLRYTRARRSNHFISFIALVSMIGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATISSTQILTNWPEL
AKKVEGHKHVVGVAPFTQLQGMLTAQGQVAGIMVSGIDPQYEKKVSIIQNHMVAGSIDNLKKGEFGIVLGKQMTDALGLG
LNDNVTLVLPEATPSPAGVVPRFKRFKIVGIFSIGAEVDSMMGYIALNDASTLLRLPDGAQGIRLKLDDIFAAPQVADDI
VRTLPPNFYASNWTYTHGNLFSAIQMEKAMVSLLLFLIVLVAAFNIVSSLVMVVTDKKSDIAILRTLGASPATITKIFMV
QGTVIGVIGTVAGAVLGVIFASSVSNIIDWVNTALGLHLFDAYFINYLPSYLRWQDVVLIVSVSLLLSFLATIYPALRAA
KIQPAEALRYE

Sequences:

>Translated_411_residues
MFKPISLYIGLRYTRARRSNHFISFIALVSMIGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATISSTQILTNWPEL
AKKVEGHKHVVGVAPFTQLQGMLTAQGQVAGIMVSGIDPQYEKKVSIIQNHMVAGSIDNLKKGEFGIVLGKQMTDALGLG
LNDNVTLVLPEATPSPAGVVPRFKRFKIVGIFSIGAEVDSMMGYIALNDASTLLRLPDGAQGIRLKLDDIFAAPQVADDI
VRTLPPNFYASNWTYTHGNLFSAIQMEKAMVSLLLFLIVLVAAFNIVSSLVMVVTDKKSDIAILRTLGASPATITKIFMV
QGTVIGVIGTVAGAVLGVIFASSVSNIIDWVNTALGLHLFDAYFINYLPSYLRWQDVVLIVSVSLLLSFLATIYPALRAA
KIQPAEALRYE
>Mature_411_residues
MFKPISLYIGLRYTRARRSNHFISFIALVSMIGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATISSTQILTNWPEL
AKKVEGHKHVVGVAPFTQLQGMLTAQGQVAGIMVSGIDPQYEKKVSIIQNHMVAGSIDNLKKGEFGIVLGKQMTDALGLG
LNDNVTLVLPEATPSPAGVVPRFKRFKIVGIFSIGAEVDSMMGYIALNDASTLLRLPDGAQGIRLKLDDIFAAPQVADDI
VRTLPPNFYASNWTYTHGNLFSAIQMEKAMVSLLLFLIVLVAAFNIVSSLVMVVTDKKSDIAILRTLGASPATITKIFMV
QGTVIGVIGTVAGAVLGVIFASSVSNIIDWVNTALGLHLFDAYFINYLPSYLRWQDVVLIVSVSLLLSFLATIYPALRAA
KIQPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=412, Percent_Identity=38.5922330097087, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=39.0887290167866, Blast_Score=251, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44538; Mature: 44538

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKPISLYIGLRYTRARRSNHFISFIALVSMIGLTLGVAVLITVLSVMNGFDRELKNRVL
CCCCEEEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GMVPQATISSTQILTNWPELAKKVEGHKHVVGVAPFTQLQGMLTAQGQVAGIMVSGIDPQ
HCCCCCCCCCCHHHHCCHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEECCCCH
YEKKVSIIQNHMVAGSIDNLKKGEFGIVLGKQMTDALGLGLNDNVTLVLPEATPSPAGVV
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PRFKRFKIVGIFSIGAEVDSMMGYIALNDASTLLRLPDGAQGIRLKLDDIFAAPQVADDI
CCCHHEEEEEEEEECHHHHHHHCEEEECCCHHEEECCCCCCCCEEEHHHHHCCHHHHHHH
VRTLPPNFYASNWTYTHGNLFSAIQMEKAMVSLLLFLIVLVAAFNIVSSLVMVVTDKKSD
HHHCCCCCEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
IAILRTLGASPATITKIFMVQGTVIGVIGTVAGAVLGVIFASSVSNIIDWVNTALGLHLF
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAYFINYLPSYLRWQDVVLIVSVSLLLSFLATIYPALRAAKIQPAEALRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MFKPISLYIGLRYTRARRSNHFISFIALVSMIGLTLGVAVLITVLSVMNGFDRELKNRVL
CCCCEEEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GMVPQATISSTQILTNWPELAKKVEGHKHVVGVAPFTQLQGMLTAQGQVAGIMVSGIDPQ
HCCCCCCCCCCHHHHCCHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEECCCCH
YEKKVSIIQNHMVAGSIDNLKKGEFGIVLGKQMTDALGLGLNDNVTLVLPEATPSPAGVV
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PRFKRFKIVGIFSIGAEVDSMMGYIALNDASTLLRLPDGAQGIRLKLDDIFAAPQVADDI
CCCHHEEEEEEEEECHHHHHHHCEEEECCCHHEEECCCCCCCCEEEHHHHHCCHHHHHHH
VRTLPPNFYASNWTYTHGNLFSAIQMEKAMVSLLLFLIVLVAAFNIVSSLVMVVTDKKSD
HHHCCCCCEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
IAILRTLGASPATITKIFMVQGTVIGVIGTVAGAVLGVIFASSVSNIIDWVNTALGLHLF
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAYFINYLPSYLRWQDVVLIVSVSLLLSFLATIYPALRAAKIQPAEALRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]