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The map label for this gene is pabC [H]

Identifier: 50085664

GI number: 50085664

Start: 2548474

End: 2549289

Strand: Reverse

Name: pabC [H]

Synonym: ACIAD2590

Alternate gene names: 50085664

Gene position: 2549289-2548474 (Counterclockwise)

Preceding gene: 50085671

Following gene: 50085663

Centisome position: 70.84

GC content: 41.54

Gene sequence:

>816_bases
ATGATGTGGTGTTTTAAAAATGCACAACCTGTCAAAGAGGTCTCTATTCAAGACCGAGCCTTGCAATACGGAGATGGGTG
TTTCACTACCGCACGAATTGAGGATGGAAAAATTCAGCTCATGCATCGTCATTTAGCACGGCTCAAGGAGTGCTGCGAAC
AATTAGACTTGTCAGTCAATTTAAACTGGATTGATGGAAGCCTTGAGCAGATGAAAACCCTGGGTTGCGTATTGACTGGT
ACCATTAAAATCCTGATCAGTCGTGGTGAAGGGCAGCGTGGTTATACGATGCCGTCGCATGCAGCAGATCTTTATATTTA
CTTTTATCCACAAAGCCATGCAATTGATCAACCTGCATACTTGAAAAGTGGTGTATTAAAAACACAGTTAGGCCTGTGTA
TGCCTAAACTTGCGGGGTTAAAAACACTTAATCGTCTTGAGCAGGTGATCTTAAAAAAAGAAGCTGACCAGCAAGGATGG
TCAGAGGCTTTAACATTGGATATAAACAATGAGGTTGTAGAAGGTGTCAGCAGTAACTGTTTTATTTATTTAAATAACAC
ATGGATTACGCCAGAACTTCGCTATAATGGCGTCCGCGGAGTGATGCGTGCTGAAATTATAGATAGAATGCAGCAGTTAG
GTATTGAGTGTATACAACGCCCAGTACAGTTGACTGAATTATCGCAGGTACAGAGCCTGTTTTTCTGTAATGCACTGCAT
CCGATGAATATTGTCACGCATTTGCAGTCGCAGACTTTACAAACCAATATTTGTACTCAGCTCTACCACATACTCAACTT
GAATCAGATTGATTGA

Upstream 100 bases:

>100_bases
TTCATAAAAAATAATAAAAAATGAATTTTATATGAATAAAAAAGAAATAAGAAAAGCTTATCGGTTTTTAAACTAAGTTT
CTAAATCAAAAGGATGATTC

Downstream 100 bases:

>100_bases
TATGCCCAAGCAGCCCACAAAACCCAAAATGAAGAAAAAACCGCAGCCTCAAACAGAGTCATGGTTTAAAACAAACAAAT
GGCTAATGGCAGCGCTCGTC

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MMWCFKNAQPVKEVSIQDRALQYGDGCFTTARIEDGKIQLMHRHLARLKECCEQLDLSVNLNWIDGSLEQMKTLGCVLTG
TIKILISRGEGQRGYTMPSHAADLYIYFYPQSHAIDQPAYLKSGVLKTQLGLCMPKLAGLKTLNRLEQVILKKEADQQGW
SEALTLDINNEVVEGVSSNCFIYLNNTWITPELRYNGVRGVMRAEIIDRMQQLGIECIQRPVQLTELSQVQSLFFCNALH
PMNIVTHLQSQTLQTNICTQLYHILNLNQID

Sequences:

>Translated_271_residues
MMWCFKNAQPVKEVSIQDRALQYGDGCFTTARIEDGKIQLMHRHLARLKECCEQLDLSVNLNWIDGSLEQMKTLGCVLTG
TIKILISRGEGQRGYTMPSHAADLYIYFYPQSHAIDQPAYLKSGVLKTQLGLCMPKLAGLKTLNRLEQVILKKEADQQGW
SEALTLDINNEVVEGVSSNCFIYLNNTWITPELRYNGVRGVMRAEIIDRMQQLGIECIQRPVQLTELSQVQSLFFCNALH
PMNIVTHLQSQTLQTNICTQLYHILNLNQID
>Mature_271_residues
MMWCFKNAQPVKEVSIQDRALQYGDGCFTTARIEDGKIQLMHRHLARLKECCEQLDLSVNLNWIDGSLEQMKTLGCVLTG
TIKILISRGEGQRGYTMPSHAADLYIYFYPQSHAIDQPAYLKSGVLKTQLGLCMPKLAGLKTLNRLEQVILKKEADQQGW
SEALTLDINNEVVEGVSSNCFIYLNNTWITPELRYNGVRGVMRAEIIDRMQQLGIECIQRPVQLTELSQVQSLFFCNALH
PMNIVTHLQSQTLQTNICTQLYHILNLNQID

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=241, Percent_Identity=37.7593360995851, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30834; Mature: 30834

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMWCFKNAQPVKEVSIQDRALQYGDGCFTTARIEDGKIQLMHRHLARLKECCEQLDLSVN
CCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
LNWIDGSLEQMKTLGCVLTGTIKILISRGEGQRGYTMPSHAADLYIYFYPQSHAIDQPAY
EEEECCCHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHH
LKSGVLKTQLGLCMPKLAGLKTLNRLEQVILKKEADQQGWSEALTLDINNEVVEGVSSNC
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCE
FIYLNNTWITPELRYNGVRGVMRAEIIDRMQQLGIECIQRPVQLTELSQVQSLFFCNALH
EEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
PMNIVTHLQSQTLQTNICTQLYHILNLNQID
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMWCFKNAQPVKEVSIQDRALQYGDGCFTTARIEDGKIQLMHRHLARLKECCEQLDLSVN
CCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
LNWIDGSLEQMKTLGCVLTGTIKILISRGEGQRGYTMPSHAADLYIYFYPQSHAIDQPAY
EEEECCCHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHH
LKSGVLKTQLGLCMPKLAGLKTLNRLEQVILKKEADQQGWSEALTLDINNEVVEGVSSNC
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCE
FIYLNNTWITPELRYNGVRGVMRAEIIDRMQQLGIECIQRPVQLTELSQVQSLFFCNALH
EEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
PMNIVTHLQSQTLQTNICTQLYHILNLNQID
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]