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The map label for this gene is fis [H]

Identifier: 50085530

GI number: 50085530

Start: 2410329

End: 2410619

Strand: Direct

Name: fis [H]

Synonym: ACIAD2446

Alternate gene names: 50085530

Gene position: 2410329-2410619 (Clockwise)

Preceding gene: 50085529

Following gene: 50085531

Centisome position: 66.98

GC content: 42.61

Gene sequence:

>291_bases
TTGATTTTCGGATTAACTCGCATGAATAGCAAATCTCCTATTTTTACTGCACAATCTGATGTTGCTCTTCGCATCCATGT
GGATCGCGCAGTTCGCCATTACTTTGCACAGTTGCAAGGTGAGCAACCATCACAAGTTTACGACATGGTGCTGGCAGAAA
TGGAGAAACCTCTTTTATCTGTTGTTCTAGAATATACGCGTGGTAACCAGACGCGCGCCGCTGAAATTTTAGGACTCAAT
CGTGGGACTTTACGTAAAAAGTTAAAAGCTCACGGATTGATGAGTGAATAA

Upstream 100 bases:

>100_bases
CAAGCTAATTGTTTCCAAGTTTTAGAGCCACTGTTTTAGGATCTAAAACAGGGTTCATTTATTTAGACCACTTTTATATA
CTGCTTTACCCTAGCGGTAT

Downstream 100 bases:

>100_bases
ATGATAAAATGCTCACGTCCTCGTGGGCATTTTTTATGCCTATTTGTTTTAATCTGTTGAACCTAAACCGTTGACTTAAT
CATGACTATTAAACGTGCTT

Product: DNA-binding protein for site-specific recombination, transcription of rRNA and tRNA operons and DNA replication

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MIFGLTRMNSKSPIFTAQSDVALRIHVDRAVRHYFAQLQGEQPSQVYDMVLAEMEKPLLSVVLEYTRGNQTRAAEILGLN
RGTLRKKLKAHGLMSE

Sequences:

>Translated_96_residues
MIFGLTRMNSKSPIFTAQSDVALRIHVDRAVRHYFAQLQGEQPSQVYDMVLAEMEKPLLSVVLEYTRGNQTRAAEILGLN
RGTLRKKLKAHGLMSE
>Mature_96_residues
MIFGLTRMNSKSPIFTAQSDVALRIHVDRAVRHYFAQLQGEQPSQVYDMVLAEMEKPLLSVVLEYTRGNQTRAAEILGLN
RGTLRKKLKAHGLMSE

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters [H]

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=71, Percent_Identity=59.1549295774648, Blast_Score=96, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 10873; Mature: 10873

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGLTRMNSKSPIFTAQSDVALRIHVDRAVRHYFAQLQGEQPSQVYDMVLAEMEKPLLS
CEECCCCCCCCCCEEECCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VVLEYTRGNQTRAAEILGLNRGTLRKKLKAHGLMSE
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIFGLTRMNSKSPIFTAQSDVALRIHVDRAVRHYFAQLQGEQPSQVYDMVLAEMEKPLLS
CEECCCCCCCCCCEEECCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VVLEYTRGNQTRAAEILGLNRGTLRKKLKAHGLMSE
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA