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The map label for this gene is yfnH [H]

Identifier: 50085459

GI number: 50085459

Start: 2326762

End: 2327451

Strand: Reverse

Name: yfnH [H]

Synonym: ACIAD2369

Alternate gene names: 50085459

Gene position: 2327451-2326762 (Counterclockwise)

Preceding gene: 50085460

Following gene: 50085458

Centisome position: 64.68

GC content: 44.49

Gene sequence:

>690_bases
ATGAAAGCCATGATTCTTGCGGCGGGTTTGGGTAATCGTATGCGCCCGCTAACTTTGCATACACCTAAACCACTTCTGGA
AGTCGGTGGAAAACCCCTGATTGTTTGGCATATCGAAAAACTCAAAAGCATAGGTGTGACTGAAATTGTCATCAATACGG
CATGGTTAGGTGATAAGCTGGTGCAGGTACTTGGTGATGGATCGGATTATGGTGTACATATTGCCTGGTCTCACGAAGGA
GAGGGACTAGAAACAGCAGGTGGCATTATTCGTGCATTACCTTTATTAGGCAAAGAGCCTTTTATTTTGGTGAATGGTGA
TGTCTGGACCAATATGGATTTTGAGTCTTTACTGTCTGTAGATTTGCAGCAGAATTTGATTCATCTGTTGCTGGTGGATA
ATCCAGTACAACATCCTCAAGGCGATTTTGTTTTGGCAGATGGACGTGTATTTACTTTTGAGCAAGGTGTGTTGGGCGAG
GCGCTCACTTACAGCGGTGTTGCGGTATTATCCCCCGAATTGTTTGCAGGTCTTGAGGATGGAAAAAGACCGCTTGCACC
ACTACTTGTTCAAGCGATGCGAAATGGACAAGCCAGTGCCGAGAAAATGCAAGCAGTTTGGGTGGATGTCGGTACTCCAG
AGCGATTAACTGTATTAGATCAACAAATTAAGCAGGGTTTATATGCTTAA

Upstream 100 bases:

>100_bases
GTCGGCCTTATGCAGAATTAAAACCATTTGTAGAATTTATTCAATATCAAGTCATGCCTAAATTTGAACAAAAATATGGT
GGGTATGAGGTAGTTAAAAA

Downstream 100 bases:

>100_bases
CTGGGTATTCACTAATCGGCAGAGACTAGGCGTAGACCGAGAAATCGGTATACTTCCTCTAAATTTTTAAGATGTGAAGC
GGATATGCATCCATTTTTGC

Product: nucleotidyl transferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKAMILAAGLGNRMRPLTLHTPKPLLEVGGKPLIVWHIEKLKSIGVTEIVINTAWLGDKLVQVLGDGSDYGVHIAWSHEG
EGLETAGGIIRALPLLGKEPFILVNGDVWTNMDFESLLSVDLQQNLIHLLLVDNPVQHPQGDFVLADGRVFTFEQGVLGE
ALTYSGVAVLSPELFAGLEDGKRPLAPLLVQAMRNGQASAEKMQAVWVDVGTPERLTVLDQQIKQGLYA

Sequences:

>Translated_229_residues
MKAMILAAGLGNRMRPLTLHTPKPLLEVGGKPLIVWHIEKLKSIGVTEIVINTAWLGDKLVQVLGDGSDYGVHIAWSHEG
EGLETAGGIIRALPLLGKEPFILVNGDVWTNMDFESLLSVDLQQNLIHLLLVDNPVQHPQGDFVLADGRVFTFEQGVLGE
ALTYSGVAVLSPELFAGLEDGKRPLAPLLVQAMRNGQASAEKMQAVWVDVGTPERLTVLDQQIKQGLYA
>Mature_229_residues
MKAMILAAGLGNRMRPLTLHTPKPLLEVGGKPLIVWHIEKLKSIGVTEIVINTAWLGDKLVQVLGDGSDYGVHIAWSHEG
EGLETAGGIIRALPLLGKEPFILVNGDVWTNMDFESLLSVDLQQNLIHLLLVDNPVQHPQGDFVLADGRVFTFEQGVLGE
ALTYSGVAVLSPELFAGLEDGKRPLAPLLVQAMRNGQASAEKMQAVWVDVGTPERLTVLDQQIKQGLYA

Specific function: Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate [H]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=226, Percent_Identity=28.7610619469027, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI11761619, Length=226, Percent_Identity=28.7610619469027, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI133931050, Length=230, Percent_Identity=29.5652173913043, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320148, Length=229, Percent_Identity=32.3144104803493, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21355443, Length=222, Percent_Identity=27.027027027027, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644084, Length=222, Percent_Identity=27.027027027027, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 24839; Mature: 24839

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMILAAGLGNRMRPLTLHTPKPLLEVGGKPLIVWHIEKLKSIGVTEIVINTAWLGDKL
CCEEEEEECCCCCCCEEEECCCCHHHHCCCCEEEEEEEHHHHHCCCEEEEEEHHHHHHHH
VQVLGDGSDYGVHIAWSHEGEGLETAGGIIRALPLLGKEPFILVNGDVWTNMDFESLLSV
HHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEECCCHHHHHHH
DLQQNLIHLLLVDNPVQHPQGDFVLADGRVFTFEQGVLGEALTYSGVAVLSPELFAGLED
HHHHCEEEEEEECCCCCCCCCCEEEECCEEEEECCCCCCCHHHHCCEEEECHHHHHCCCC
GKRPLAPLLVQAMRNGQASAEKMQAVWVDVGTPERLTVLDQQIKQGLYA
CCCCHHHHHHHHHHCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAMILAAGLGNRMRPLTLHTPKPLLEVGGKPLIVWHIEKLKSIGVTEIVINTAWLGDKL
CCEEEEEECCCCCCCEEEECCCCHHHHCCCCEEEEEEEHHHHHCCCEEEEEEHHHHHHHH
VQVLGDGSDYGVHIAWSHEGEGLETAGGIIRALPLLGKEPFILVNGDVWTNMDFESLLSV
HHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEECCCHHHHHHH
DLQQNLIHLLLVDNPVQHPQGDFVLADGRVFTFEQGVLGEALTYSGVAVLSPELFAGLED
HHHHCEEEEEEECCCCCCCCCCEEEECCEEEEECCCCCCCHHHHCCEEEECHHHHHCCCC
GKRPLAPLLVQAMRNGQASAEKMQAVWVDVGTPERLTVLDQQIKQGLYA
CCCCHHHHHHHHHHCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]