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The map label for this gene is ycfH [H]

Identifier: 50085450

GI number: 50085450

Start: 2318379

End: 2319152

Strand: Reverse

Name: ycfH [H]

Synonym: ACIAD2359

Alternate gene names: 50085450

Gene position: 2319152-2318379 (Counterclockwise)

Preceding gene: 50085451

Following gene: 50085449

Centisome position: 64.45

GC content: 41.99

Gene sequence:

>774_bases
GTGTTTGTAGATACACATTGCCATTTGACAATGCTTGATTTGACACCTTATCAGGGTAATCTTGATCAGGCGCTGGTAGA
GGCTCGTGAAGCTGGTGTATCAAAATTTATGAGCATTTCAGTCAATCTGGATGATCATATTGCTTTGGCCGAAATTTCTG
CTCGTCATGACGATGTTGGTTATAGTGTAGGCGTGCATCCATGTGAAGATGCCGCAACAATGGCACGTGCAACAACCGAG
TTTTTGGTAGAGTTGGCACAGTCAGATAAAGTCTGGGCGCTGGGTGAAACAGGCCTAGATTATTATCATAGCGATGAATA
TGTAGATGAACAAAAAGCCTGCTTTGCACGGCATATTGCAGCGTCAAAGATCGTGAAAAAGCCTGTGGTGGTACATACCC
GATCTGCTAAGCGCGATACTATCGATATTATTCGGGCTGAAGCATCTACACATGGTATTTTGCACTGCTTCACAGAGGAT
TGGGAAACTGCAAAAGCTGCACTTGACTGTGGCTATTATATTTCGTTTTCTGGCATTATTTCCTTTAAAAATGCACAGGA
TTTACGTGATGTCGCCAAACAGGTTCCTTTGGAACGGGTATTGATTGAAACAGATAGTCCTTATCTAGCACCTGTACCGT
ATCGTGGTAAATCGAATGAACCCAAATATGTACCTTATGTTGCTCAGGCTTTAAGTGATTTATACGGTAAACCGCTTGAA
GAAATTGCTTTGATTACACGACAAAATTTTGACAACCTTTTGGCTGCTAAATAG

Upstream 100 bases:

>100_bases
AAAGAGGAGCTTATTATAAGGCCGAAGCCGAAAAAATTCTGGCAGGCAGTATGAGCTCTGACCGTTCAAACTTTACCATG
TAATTATGAGGAAATAAGCT

Downstream 100 bases:

>100_bases
TTTTAAAAATATCATTATAAAGAGAGTGATCACGTGAAGATGGATCGTCAAGCCCAGTTTCGGGCGAGAGAAGCGTTGAT
ATTTGAAGTGGCAGAACAAC

Product: deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MFVDTHCHLTMLDLTPYQGNLDQALVEAREAGVSKFMSISVNLDDHIALAEISARHDDVGYSVGVHPCEDAATMARATTE
FLVELAQSDKVWALGETGLDYYHSDEYVDEQKACFARHIAASKIVKKPVVVHTRSAKRDTIDIIRAEASTHGILHCFTED
WETAKAALDCGYYISFSGIISFKNAQDLRDVAKQVPLERVLIETDSPYLAPVPYRGKSNEPKYVPYVAQALSDLYGKPLE
EIALITRQNFDNLLAAK

Sequences:

>Translated_257_residues
MFVDTHCHLTMLDLTPYQGNLDQALVEAREAGVSKFMSISVNLDDHIALAEISARHDDVGYSVGVHPCEDAATMARATTE
FLVELAQSDKVWALGETGLDYYHSDEYVDEQKACFARHIAASKIVKKPVVVHTRSAKRDTIDIIRAEASTHGILHCFTED
WETAKAALDCGYYISFSGIISFKNAQDLRDVAKQVPLERVLIETDSPYLAPVPYRGKSNEPKYVPYVAQALSDLYGKPLE
EIALITRQNFDNLLAAK
>Mature_257_residues
MFVDTHCHLTMLDLTPYQGNLDQALVEAREAGVSKFMSISVNLDDHIALAEISARHDDVGYSVGVHPCEDAATMARATTE
FLVELAQSDKVWALGETGLDYYHSDEYVDEQKACFARHIAASKIVKKPVVVHTRSAKRDTIDIIRAEASTHGILHCFTED
WETAKAALDCGYYISFSGIISFKNAQDLRDVAKQVPLERVLIETDSPYLAPVPYRGKSNEPKYVPYVAQALSDLYGKPLE
EIALITRQNFDNLLAAK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=260, Percent_Identity=29.2307692307692, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI110349730, Length=261, Percent_Identity=29.5019157088123, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI226061853, Length=266, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI225903424, Length=225, Percent_Identity=28.8888888888889, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI226061614, Length=250, Percent_Identity=28.8, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI14042943, Length=203, Percent_Identity=29.5566502463054, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI225903439, Length=158, Percent_Identity=30.379746835443, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=44.921875, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI87082439, Length=248, Percent_Identity=27.0161290322581, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI48994985, Length=246, Percent_Identity=27.6422764227642, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=265, Percent_Identity=29.0566037735849, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=211, Percent_Identity=28.9099526066351, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=27.0676691729323, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=215, Percent_Identity=28.8372093023256, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24648690, Length=263, Percent_Identity=28.5171102661597, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586117, Length=264, Percent_Identity=26.5151515151515, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330018, Length=264, Percent_Identity=26.5151515151515, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28595; Mature: 28595

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDTHCHLTMLDLTPYQGNLDQALVEAREAGVSKFMSISVNLDDHIALAEISARHDDVG
CEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCEEEEHHHCCCCCCC
YSVGVHPCEDAATMARATTEFLVELAQSDKVWALGETGLDYYHSDEYVDEQKACFARHIA
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
ASKIVKKPVVVHTRSAKRDTIDIIRAEASTHGILHCFTEDWETAKAALDCGYYISFSGII
HHHHHHCCEEEEECCCCCCHHHHEEECCCCCCEEEEECCCHHHHHHHHCCCEEEEEEEEE
SFKNAQDLRDVAKQVPLERVLIETDSPYLAPVPYRGKSNEPKYVPYVAQALSDLYGKPLE
EECCHHHHHHHHHHCCHHEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHH
EIALITRQNFDNLLAAK
HHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MFVDTHCHLTMLDLTPYQGNLDQALVEAREAGVSKFMSISVNLDDHIALAEISARHDDVG
CEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCEEEEHHHCCCCCCC
YSVGVHPCEDAATMARATTEFLVELAQSDKVWALGETGLDYYHSDEYVDEQKACFARHIA
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
ASKIVKKPVVVHTRSAKRDTIDIIRAEASTHGILHCFTEDWETAKAALDCGYYISFSGII
HHHHHHCCEEEEECCCCCCHHHHEEECCCCCCEEEEECCCHHHHHHHHCCCEEEEEEEEE
SFKNAQDLRDVAKQVPLERVLIETDSPYLAPVPYRGKSNEPKYVPYVAQALSDLYGKPLE
EECCHHHHHHHHHHCCHHEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHH
EIALITRQNFDNLLAAK
HHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]