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The map label for this gene is fhuE [H]

Identifier: 50085419

GI number: 50085419

Start: 2287975

End: 2290173

Strand: Direct

Name: fhuE [H]

Synonym: ACIAD2325

Alternate gene names: 50085419

Gene position: 2287975-2290173 (Clockwise)

Preceding gene: 50085417

Following gene: 50085420

Centisome position: 63.58

GC content: 38.74

Gene sequence:

>2199_bases
ATGATAACTATTTACATTAACATTTATATCATGTCCCTTAATCCTCCATCATTTTTGAAATTGTCTCTGGTTACCTTAGC
AATTTTGCAAGTTCAGCTTGCACAAGCACAAGACACCACTCTACCTGTTATTCAACTTCAAGCTGAAGATAGTGAGGGGC
AAAGTTCTGAAAAGACTAGATCCTATATTATTAAAAAAAGCAGTAGTGCAACCAAGCTGAATATTGATGCAAAAGAAACT
CCACAAACGGTGAATGTTGTCACTCGCCAGCAAATGGATGACTTCAATTTAAACTCTACACGTAAAGTTCTTGAAAATAC
TCCTGGTGTCACAGTTTCAAATCAAGAAACTGAACGTACAACCTATATGTCTCGTGGCTTTGAAATATCAAACATTCTCA
CTGATGGCGTTGGCTTTCCACTTTCCAACTATAATTATAACAACACCAATCCAGATACTTATTTTTACGATCGAGTCGAA
GTGATTAAAGGTGCTGATGCGCTTACGAACGCTTTCGGAGACCCAAGTGCCACCATTAATAATATTCGAAAACGTCCAAC
TAAAGAATTTCAAGCGAATGCTGGCATCAGTTATGGTTCATGGAACACTCAACGTTATGAAGCAGATGTATCTGGTGCTT
TAACCCAAGATGGTCGTGTTCGTGGCCGAATGATGGGCTTTGAGCAAACGGGTGACTCTTATCTAGATCATTATTCATCA
GAAAAAAATGGCTTTGCTGGTATTTTGGATGCCGATTTAACCGATACTACGACACTAACAGTGGGCTATAGCGAACAGCA
GAATAATCCGAATGCAAATAACTGGGGTGCTTTACCGCTTTTAGATAATAATGGTCATCAAATTTCCTATAGCCGTTCAT
ACAACCCAAATCCAGACTGGACACACTGGGATCATAAAACTCAAGAAGCATTTGCAGAACTCAAACAAAAACTTGGCGAA
AAATGGACAGCCAAACTGACTTACAATTACACCAATACACAACATGACAGTAGATTACTCTACTATTACGGGAGCCCAAC
AGCACAAGGTAGCGATGTATCTTTAACGGCATGGGGGGGCCAAGAAAGAAACGAACAAAAGTTACTTAATTTTGACTTGC
AAGGGAGTTATGCACTTTTTGGCCAGGAGCATGAAGCTGCTCTGGGCTATAGCCATATTAAAAATAAACAGCATGATCTG
CAATCCAGTGGCTATATAAACGATAGCAATGTCGTTGATAAATACAATGACAAAGATGAATTTCTCGGTCAATTTACTAC
CAATTGGACAAGCTGGACACCTCAATCTGTGACATGGTCAGATTTTTCCGAAGCTGCAAATTACACACAGAGAATTGATT
CATTTTACGCTGCCACCCGCCTACACCTCACAAATGATTTAAAATTGATTATAGGCGGTAATTATGTACAAGCTGAAAGT
AATGGCTATAGTTACGGCTCAAACATGTCTTATGATAAAGACAAGTTTTCTCCATATGCAGGGATCACCTACAATTTTAC
CCCCGAATATACAGGATATGCGAGCTACACCTCTATTTTTAGACCGCAAACAGGAATTGATCAAACCACTAATCAGGCTT
TGAAAGCTGTTGAAGGAAAAAGCTACGAAGTTGGTATGAAGAGCTCTTGGCTGGATAATAAGCTAATAGGAACGCTGGCA
GTCTTTAAAACCGAGCAAAATAATTATCAATTAAGAAGCTCAGATGGAAACCCACTTAATCGCAAAGTTTTGACCAGTGA
TTTAGATTCACAAGGTGTTGAAGTTGGCTTGGCAGGTCAGCTTACAGATCATGTCAATCTTGCATTTGGTTACGCACAGT
TTAGTATTAAAGACAAAAAGAATGGTGGTGAAGCTCGTACCTATAATCCATCTCAAACGTTGAATTTACTGGCGACTTAT
ACAGTTCCTACCCTACCGAAGCTGAAAGTTGGAGCAGGTTTACGCTGGCAAAATGCGATTAAGCTTTATGATGTGAGTTT
AGGAAATTCTAATCTGATTAAACAAGATGCTTATGGTTTGGTAGATATCATGGCAAGTTATGAGATTAACAATCATCTAA
GTGTTCAAGTTAATGGGAATAATATAACGGACAAAAAATATTTAAATAGCTTTCCAGATGGTCAAGCTTTTTACGGCGAA
CCCGCCAATTACACTGTTGCAGTGAAGTTTAAATATTAG

Upstream 100 bases:

>100_bases
TTTTCAAGCAAAATTTAAAATCACATTCGAATATCCATTTAACATTTGAATTAACAATCATAGTTTTTATTGTGGTTTAC
ATTACTTAATAATAAAATAA

Downstream 100 bases:

>100_bases
TTAACAAAGCCAATTCTCCATCCCGAGAATTGGCTTTAATTTTTTATCAGTTGAACATCATATGAGCAAAACACATTCAC
TGACGTATACCTACAGGCTC

Product: ferric siderophore receptor protein

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MITIYINIYIMSLNPPSFLKLSLVTLAILQVQLAQAQDTTLPVIQLQAEDSEGQSSEKTRSYIIKKSSSATKLNIDAKET
PQTVNVVTRQQMDDFNLNSTRKVLENTPGVTVSNQETERTTYMSRGFEISNILTDGVGFPLSNYNYNNTNPDTYFYDRVE
VIKGADALTNAFGDPSATINNIRKRPTKEFQANAGISYGSWNTQRYEADVSGALTQDGRVRGRMMGFEQTGDSYLDHYSS
EKNGFAGILDADLTDTTTLTVGYSEQQNNPNANNWGALPLLDNNGHQISYSRSYNPNPDWTHWDHKTQEAFAELKQKLGE
KWTAKLTYNYTNTQHDSRLLYYYGSPTAQGSDVSLTAWGGQERNEQKLLNFDLQGSYALFGQEHEAALGYSHIKNKQHDL
QSSGYINDSNVVDKYNDKDEFLGQFTTNWTSWTPQSVTWSDFSEAANYTQRIDSFYAATRLHLTNDLKLIIGGNYVQAES
NGYSYGSNMSYDKDKFSPYAGITYNFTPEYTGYASYTSIFRPQTGIDQTTNQALKAVEGKSYEVGMKSSWLDNKLIGTLA
VFKTEQNNYQLRSSDGNPLNRKVLTSDLDSQGVEVGLAGQLTDHVNLAFGYAQFSIKDKKNGGEARTYNPSQTLNLLATY
TVPTLPKLKVGAGLRWQNAIKLYDVSLGNSNLIKQDAYGLVDIMASYEINNHLSVQVNGNNITDKKYLNSFPDGQAFYGE
PANYTVAVKFKY

Sequences:

>Translated_732_residues
MITIYINIYIMSLNPPSFLKLSLVTLAILQVQLAQAQDTTLPVIQLQAEDSEGQSSEKTRSYIIKKSSSATKLNIDAKET
PQTVNVVTRQQMDDFNLNSTRKVLENTPGVTVSNQETERTTYMSRGFEISNILTDGVGFPLSNYNYNNTNPDTYFYDRVE
VIKGADALTNAFGDPSATINNIRKRPTKEFQANAGISYGSWNTQRYEADVSGALTQDGRVRGRMMGFEQTGDSYLDHYSS
EKNGFAGILDADLTDTTTLTVGYSEQQNNPNANNWGALPLLDNNGHQISYSRSYNPNPDWTHWDHKTQEAFAELKQKLGE
KWTAKLTYNYTNTQHDSRLLYYYGSPTAQGSDVSLTAWGGQERNEQKLLNFDLQGSYALFGQEHEAALGYSHIKNKQHDL
QSSGYINDSNVVDKYNDKDEFLGQFTTNWTSWTPQSVTWSDFSEAANYTQRIDSFYAATRLHLTNDLKLIIGGNYVQAES
NGYSYGSNMSYDKDKFSPYAGITYNFTPEYTGYASYTSIFRPQTGIDQTTNQALKAVEGKSYEVGMKSSWLDNKLIGTLA
VFKTEQNNYQLRSSDGNPLNRKVLTSDLDSQGVEVGLAGQLTDHVNLAFGYAQFSIKDKKNGGEARTYNPSQTLNLLATY
TVPTLPKLKVGAGLRWQNAIKLYDVSLGNSNLIKQDAYGLVDIMASYEINNHLSVQVNGNNITDKKYLNSFPDGQAFYGE
PANYTVAVKFKY
>Mature_732_residues
MITIYINIYIMSLNPPSFLKLSLVTLAILQVQLAQAQDTTLPVIQLQAEDSEGQSSEKTRSYIIKKSSSATKLNIDAKET
PQTVNVVTRQQMDDFNLNSTRKVLENTPGVTVSNQETERTTYMSRGFEISNILTDGVGFPLSNYNYNNTNPDTYFYDRVE
VIKGADALTNAFGDPSATINNIRKRPTKEFQANAGISYGSWNTQRYEADVSGALTQDGRVRGRMMGFEQTGDSYLDHYSS
EKNGFAGILDADLTDTTTLTVGYSEQQNNPNANNWGALPLLDNNGHQISYSRSYNPNPDWTHWDHKTQEAFAELKQKLGE
KWTAKLTYNYTNTQHDSRLLYYYGSPTAQGSDVSLTAWGGQERNEQKLLNFDLQGSYALFGQEHEAALGYSHIKNKQHDL
QSSGYINDSNVVDKYNDKDEFLGQFTTNWTSWTPQSVTWSDFSEAANYTQRIDSFYAATRLHLTNDLKLIIGGNYVQAES
NGYSYGSNMSYDKDKFSPYAGITYNFTPEYTGYASYTSIFRPQTGIDQTTNQALKAVEGKSYEVGMKSSWLDNKLIGTLA
VFKTEQNNYQLRSSDGNPLNRKVLTSDLDSQGVEVGLAGQLTDHVNLAFGYAQFSIKDKKNGGEARTYNPSQTLNLLATY
TVPTLPKLKVGAGLRWQNAIKLYDVSLGNSNLIKQDAYGLVDIMASYEINNHLSVQVNGNNITDKKYLNSFPDGQAFYGE
PANYTVAVKFKY

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=743, Percent_Identity=33.9165545087483, Blast_Score=407, Evalue=1e-114,
Organism=Escherichia coli, GI1786344, Length=767, Percent_Identity=22.0338983050847, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1787024, Length=257, Percent_Identity=28.0155642023346, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81956; Mature: 81956

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIYINIYIMSLNPPSFLKLSLVTLAILQVQLAQAQDTTLPVIQLQAEDSEGQSSEKTR
CEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHH
SYIIKKSSSATKLNIDAKETPQTVNVVTRQQMDDFNLNSTRKVLENTPGVTVSNQETERT
HEEEECCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEECCCCHHHH
TYMSRGFEISNILTDGVGFPLSNYNYNNTNPDTYFYDRVEVIKGADALTNAFGDPSATIN
HHHHCCEEHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHCCCCCCHHHH
NIRKRPTKEFQANAGISYGSWNTQRYEADVSGALTQDGRVRGRMMGFEQTGDSYLDHYSS
HHHCCCCHHHHHCCCCEECCCCCEEEECCCCCCCCCCCCEEEEEECCHHCCCHHHHHCCC
EKNGFAGILDADLTDTTTLTVGYSEQQNNPNANNWGALPLLDNNGHQISYSRSYNPNPDW
CCCCEEEEEECCCCCCEEEEEEEHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCC
THWDHKTQEAFAELKQKLGEKWTAKLTYNYTNTQHDSRLLYYYGSPTAQGSDVSLTAWGG
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCC
QERNEQKLLNFDLQGSYALFGQEHEAALGYSHIKNKQHDLQSSGYINDSNVVDKYNDKDE
CCCCCCEEEEEECCCCEEEECCCCCHHHCHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHH
FLGQFTTNWTSWTPQSVTWSDFSEAANYTQRIDSFYAATRLHLTNDLKLIIGGNYVQAES
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCEEEECC
NGYSYGSNMSYDKDKFSPYAGITYNFTPEYTGYASYTSIFRPQTGIDQTTNQALKAVEGK
CCCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCC
SYEVGMKSSWLDNKLIGTLAVFKTEQNNYQLRSSDGNPLNRKVLTSDLDSQGVEVGLAGQ
CEEECCCCCCCCCHHEEEEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEECC
LTDHVNLAFGYAQFSIKDKKNGGEARTYNPSQTLNLLATYTVPTLPKLKVGAGLRWQNAI
CCCCEEEEEEEEEEEEEECCCCCCCEEECCCHHEEEEEEECCCCCCCEECCCCCCCCCCE
KLYDVSLGNSNLIKQDAYGLVDIMASYEINNHLSVQVNGNNITDKKYLNSFPDGQAFYGE
EEEEEECCCCCCCHHHCCCCEEEHEEEEECCEEEEEECCCCCCCHHHHHCCCCCCEECCC
PANYTVAVKFKY
CCCEEEEEEECC
>Mature Secondary Structure
MITIYINIYIMSLNPPSFLKLSLVTLAILQVQLAQAQDTTLPVIQLQAEDSEGQSSEKTR
CEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHH
SYIIKKSSSATKLNIDAKETPQTVNVVTRQQMDDFNLNSTRKVLENTPGVTVSNQETERT
HEEEECCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEECCCCHHHH
TYMSRGFEISNILTDGVGFPLSNYNYNNTNPDTYFYDRVEVIKGADALTNAFGDPSATIN
HHHHCCEEHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHCCCCCCHHHH
NIRKRPTKEFQANAGISYGSWNTQRYEADVSGALTQDGRVRGRMMGFEQTGDSYLDHYSS
HHHCCCCHHHHHCCCCEECCCCCEEEECCCCCCCCCCCCEEEEEECCHHCCCHHHHHCCC
EKNGFAGILDADLTDTTTLTVGYSEQQNNPNANNWGALPLLDNNGHQISYSRSYNPNPDW
CCCCEEEEEECCCCCCEEEEEEEHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCC
THWDHKTQEAFAELKQKLGEKWTAKLTYNYTNTQHDSRLLYYYGSPTAQGSDVSLTAWGG
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCC
QERNEQKLLNFDLQGSYALFGQEHEAALGYSHIKNKQHDLQSSGYINDSNVVDKYNDKDE
CCCCCCEEEEEECCCCEEEECCCCCHHHCHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHH
FLGQFTTNWTSWTPQSVTWSDFSEAANYTQRIDSFYAATRLHLTNDLKLIIGGNYVQAES
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCEEEECC
NGYSYGSNMSYDKDKFSPYAGITYNFTPEYTGYASYTSIFRPQTGIDQTTNQALKAVEGK
CCCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCC
SYEVGMKSSWLDNKLIGTLAVFKTEQNNYQLRSSDGNPLNRKVLTSDLDSQGVEVGLAGQ
CEEECCCCCCCCCHHEEEEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEECC
LTDHVNLAFGYAQFSIKDKKNGGEARTYNPSQTLNLLATYTVPTLPKLKVGAGLRWQNAI
CCCCEEEEEEEEEEEEEECCCCCCCEEECCCHHEEEEEEECCCCCCCEECCCCCCCCCCE
KLYDVSLGNSNLIKQDAYGLVDIMASYEINNHLSVQVNGNNITDKKYLNSFPDGQAFYGE
EEEEEECCCCCCCHHHCCCCEEEHEEEEECCEEEEEECCCCCCCHHHHHCCCCCCEECCC
PANYTVAVKFKY
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]