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The map label for this gene is ycfF [C]

Identifier: 50085413

GI number: 50085413

Start: 2282675

End: 2283088

Strand: Direct

Name: ycfF [C]

Synonym: ACIAD2318

Alternate gene names: 50085413

Gene position: 2282675-2283088 (Clockwise)

Preceding gene: 50085412

Following gene: 50085414

Centisome position: 63.43

GC content: 41.55

Gene sequence:

>414_bases
ATGGCATATAACGATCAGAACATATTTGCTCGTATTCTTCGCGATGAACTGCCTGCAATTAAAGTCTATGAAGATGACCA
AGTATTGGCTTTTATGGACATTATGCCTCAAGCGGATGGTCATACTTTGGTTATTCCTAAAGTTCCTGCTGAAACTTTAT
TGGACTTGCCACCAGAAGCAGCAGCCTACACCATTCAGATTGTGCAGAAAGTTGCAAAAGCAATTGAAACAGGTCTCGAT
GTCAAGGGAATCGTTTTAATGCAGCTTTCTGGTTCATCTGCTGGACAAACCGTTCCACATGTTCATTTCCACCTTATTCC
AAGCTCAATCCATGAATTAGGCCGACATGCGGCCCAAATGGGTGATCAAGAAAAAATTAAGGCCTTAGCTGAAAAAATCA
AAGCAGCGCTTTAA

Upstream 100 bases:

>100_bases
CCAAAATTTTCAGATAAAGAGCAGCAACGTCTTGACCAGATCAAGGATCGTCAGAAAGAATTGAATTGTAAATAAGAACT
GCACTTTATAAGGAAACACA

Downstream 100 bases:

>100_bases
ATAAAATGATGTATATCAAAGGAGCTAAGGCTCCTTTTTTATTTTTTTAAATAATAAAAATAAAGAGTTAGTTCTAAAAA
ATCGTATATATCGTCATTAA

Product: histidine triad family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MAYNDQNIFARILRDELPAIKVYEDDQVLAFMDIMPQADGHTLVIPKVPAETLLDLPPEAAAYTIQIVQKVAKAIETGLD
VKGIVLMQLSGSSAGQTVPHVHFHLIPSSIHELGRHAAQMGDQEKIKALAEKIKAAL

Sequences:

>Translated_137_residues
MAYNDQNIFARILRDELPAIKVYEDDQVLAFMDIMPQADGHTLVIPKVPAETLLDLPPEAAAYTIQIVQKVAKAIETGLD
VKGIVLMQLSGSSAGQTVPHVHFHLIPSSIHELGRHAAQMGDQEKIKALAEKIKAAL
>Mature_136_residues
AYNDQNIFARILRDELPAIKVYEDDQVLAFMDIMPQADGHTLVIPKVPAETLLDLPPEAAAYTIQIVQKVAKAIETGLDV
KGIVLMQLSGSSAGQTVPHVHFHLIPSSIHELGRHAAQMGDQEKIKALAEKIKAAL

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=102, Percent_Identity=41.1764705882353, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1787346, Length=105, Percent_Identity=37.1428571428571, Blast_Score=60, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17556280, Length=125, Percent_Identity=32.8, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320078, Length=133, Percent_Identity=37.593984962406, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=36.1111111111111, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=36.1111111111111, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 14944; Mature: 14812

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYNDQNIFARILRDELPAIKVYEDDQVLAFMDIMPQADGHTLVIPKVPAETLLDLPPEA
CCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCHHHHHCCCCCH
AAYTIQIVQKVAKAIETGLDVKGIVLMQLSGSSAGQTVPHVHFHLIPSSIHELGRHAAQM
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHC
GDQEKIKALAEKIKAAL
CCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYNDQNIFARILRDELPAIKVYEDDQVLAFMDIMPQADGHTLVIPKVPAETLLDLPPEA
CCCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCHHHHHCCCCCH
AAYTIQIVQKVAKAIETGLDVKGIVLMQLSGSSAGQTVPHVHFHLIPSSIHELGRHAAQM
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHC
GDQEKIKALAEKIKAAL
CCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978084; 9403685 [H]