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The map label for this gene is pqqL [C]

Identifier: 50085395

GI number: 50085395

Start: 2268424

End: 2269812

Strand: Direct

Name: pqqL [C]

Synonym: ACIAD2298

Alternate gene names: 50085395

Gene position: 2268424-2269812 (Clockwise)

Preceding gene: 50085390

Following gene: 50085396

Centisome position: 63.04

GC content: 41.32

Gene sequence:

>1389_bases
GTGTTGGCCCCCACCCGATTTTTCTTATTTTTTACGCGTTCAATAGCGCGCTTTTATTTACTATGTTTATTCTACTGCAT
CTCTGCTTCTCCTGTATTTGCGGCTGAAAGCCAGTTAGCACGAACCACCTTTGAAACAACCTTAGCAAACGGTTTAAAAG
TCATTATTCGCGAAGACCATCGTGCACCGATTGTAATTACACAAATCTGGTATGGGATTGGTAGCGGAGATGAATCTGGA
AATTTACTAGGTATTTCCCATGCACTTGAACACATGATGTTTAAAGGAACGGCTAAAGTTCCAAATAATGAATTTACTCG
CTTGAGCAGACTCTACGGTGGTCGGGTCAATGCAGCGACCTTCACCAACTATACATATTACGATCAGCTTTATCCCAAAG
CTTATTTGCCCATGGCACTAGAGCTTGAAGCAGATCGCATGCAGCATCTGCGTTTACGTCAAAGTGACTTTGATACAGAA
ATTAAAGTTGTGATGGAAGAACGACGCCAACGAACAGATGATAATCCATCTGTTTTGGCATTCGAACGTTTTAAATGGCT
TGCCTATCCCACCAGTCATTATCGCCAGCCTGTCATTGGCTATATGAAAAATTTACAAAACCTACAGCTTAAAGATTTAA
AAAGCTGGTACAAAAACTGGTACGTTCCTAACAATGCTACACTCATTATTATTGGTGATGTCGATGCTGAAACAACCTTA
AACACAGTAAAAACCTATTTTGGAAAAATTCCTTCTGCTAGATTGCCACCAAGAAATGACCTGCTCGAATTTGATCGTGT
GGGTTACAGGCACATGGAAGTTCATTTACCTGTAAAGGTGCCTAATTTATTCATGGCTTGGAACGTCAGGTCGTTGGTGA
CAGCGAAGAACCCTCAAGATGCCTACGCATTAACCATTATTCAGTCACTACTCAATGGCGGAATTTCATCAAGATTACAA
GAGCAGCTTGTAAGAAAGAAAAAAATCCTAACGTCGGTCAATGTCAGCTACGAGCCTTATAACCGTGGCGACAGTCTGTT
TACGATCACGGCTTTGCCTGTCGAAGGCGTCAGTCTTGAAGATGCCCAAAAAGCGATTCAGCAACAGATTGATATCTTAA
AAAATCAACCTCTTGATCCCAATGAATTAGAACGTGTCCGCGCAAATTTTGTTTCGCATCTGGTATTTGGTCAAGATGAT
ATTGTCGGTCAGGCTCATCTCATGGGTAATCTGGAAGTGAATGGTTTAAGTTATCGTCTGATCGACGAACTTCCTACACA
TTATGGCACAGTCAAACAACAGGATATTCAACGTGTCGCCAATGCTTATCTGGTGAGAGAGAATCTGACGAGTTTGTATT
TATTGCCCGATTCTCAAGATAAACCATAA

Upstream 100 bases:

>100_bases
AAAATATTCATAACTAAAACACAACATGAAAACCTTGTTTTCAAAATCTGTTTTTTCAACAATGGTTTTCATGATAAAAA
TCATTTTCTTGGACAGGATA

Downstream 100 bases:

>100_bases
TCAAGGAAAAAATAATGTCTTATTTCTCTTACTCCCCCATTTTTCTTGTCGGTTTATTGGTGAGTAGCTTAAGTCATGCA
GAAGTTGTCGAAGCGAATGG

Product: zinc protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MLAPTRFFLFFTRSIARFYLLCLFYCISASPVFAAESQLARTTFETTLANGLKVIIREDHRAPIVITQIWYGIGSGDESG
NLLGISHALEHMMFKGTAKVPNNEFTRLSRLYGGRVNAATFTNYTYYDQLYPKAYLPMALELEADRMQHLRLRQSDFDTE
IKVVMEERRQRTDDNPSVLAFERFKWLAYPTSHYRQPVIGYMKNLQNLQLKDLKSWYKNWYVPNNATLIIIGDVDAETTL
NTVKTYFGKIPSARLPPRNDLLEFDRVGYRHMEVHLPVKVPNLFMAWNVRSLVTAKNPQDAYALTIIQSLLNGGISSRLQ
EQLVRKKKILTSVNVSYEPYNRGDSLFTITALPVEGVSLEDAQKAIQQQIDILKNQPLDPNELERVRANFVSHLVFGQDD
IVGQAHLMGNLEVNGLSYRLIDELPTHYGTVKQQDIQRVANAYLVRENLTSLYLLPDSQDKP

Sequences:

>Translated_462_residues
MLAPTRFFLFFTRSIARFYLLCLFYCISASPVFAAESQLARTTFETTLANGLKVIIREDHRAPIVITQIWYGIGSGDESG
NLLGISHALEHMMFKGTAKVPNNEFTRLSRLYGGRVNAATFTNYTYYDQLYPKAYLPMALELEADRMQHLRLRQSDFDTE
IKVVMEERRQRTDDNPSVLAFERFKWLAYPTSHYRQPVIGYMKNLQNLQLKDLKSWYKNWYVPNNATLIIIGDVDAETTL
NTVKTYFGKIPSARLPPRNDLLEFDRVGYRHMEVHLPVKVPNLFMAWNVRSLVTAKNPQDAYALTIIQSLLNGGISSRLQ
EQLVRKKKILTSVNVSYEPYNRGDSLFTITALPVEGVSLEDAQKAIQQQIDILKNQPLDPNELERVRANFVSHLVFGQDD
IVGQAHLMGNLEVNGLSYRLIDELPTHYGTVKQQDIQRVANAYLVRENLTSLYLLPDSQDKP
>Mature_462_residues
MLAPTRFFLFFTRSIARFYLLCLFYCISASPVFAAESQLARTTFETTLANGLKVIIREDHRAPIVITQIWYGIGSGDESG
NLLGISHALEHMMFKGTAKVPNNEFTRLSRLYGGRVNAATFTNYTYYDQLYPKAYLPMALELEADRMQHLRLRQSDFDTE
IKVVMEERRQRTDDNPSVLAFERFKWLAYPTSHYRQPVIGYMKNLQNLQLKDLKSWYKNWYVPNNATLIIIGDVDAETTL
NTVKTYFGKIPSARLPPRNDLLEFDRVGYRHMEVHLPVKVPNLFMAWNVRSLVTAKNPQDAYALTIIQSLLNGGISSRLQ
EQLVRKKKILTSVNVSYEPYNRGDSLFTITALPVEGVSLEDAQKAIQQQIDILKNQPLDPNELERVRANFVSHLVFGQDD
IVGQAHLMGNLEVNGLSYRLIDELPTHYGTVKQQDIQRVANAYLVRENLTSLYLLPDSQDKP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=228, Percent_Identity=27.6315789473684, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI94538354, Length=223, Percent_Identity=29.1479820627803, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1787770, Length=216, Percent_Identity=31.0185185185185, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17553678, Length=268, Percent_Identity=23.8805970149254, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72001443, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=269, Percent_Identity=23.7918215613383, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357875, Length=233, Percent_Identity=27.0386266094421, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24646943, Length=233, Percent_Identity=27.0386266094421, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 52982; Mature: 52982

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPTRFFLFFTRSIARFYLLCLFYCISASPVFAAESQLARTTFETTLANGLKVIIREDH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCC
RAPIVITQIWYGIGSGDESGNLLGISHALEHMMFKGTAKVPNNEFTRLSRLYGGRVNAAT
CCCEEEEEEHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEE
FTNYTYYDQLYPKAYLPMALELEADRMQHLRLRQSDFDTEIKVVMEERRQRTDDNPSVLA
EECEEEHHHHCCHHHCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEE
FERFKWLAYPTSHYRQPVIGYMKNLQNLQLKDLKSWYKNWYVPNNATLIIIGDVDAETTL
EEHHEEEECCHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
NTVKTYFGKIPSARLPPRNDLLEFDRVGYRHMEVHLPVKVPNLFMAWNVRSLVTAKNPQD
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEEEEEEECCCEEEEECHHHHHCCCCCCH
AYALTIIQSLLNGGISSRLQEQLVRKKKILTSVNVSYEPYNRGDSLFTITALPVEGVSLE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHH
DAQKAIQQQIDILKNQPLDPNELERVRANFVSHLVFGQDDIVGQAHLMGNLEVNGLSYRL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECEEECCEEEHH
IDELPTHYGTVKQQDIQRVANAYLVRENLTSLYLLPDSQDKP
HHHCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure
MLAPTRFFLFFTRSIARFYLLCLFYCISASPVFAAESQLARTTFETTLANGLKVIIREDH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCC
RAPIVITQIWYGIGSGDESGNLLGISHALEHMMFKGTAKVPNNEFTRLSRLYGGRVNAAT
CCCEEEEEEHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEE
FTNYTYYDQLYPKAYLPMALELEADRMQHLRLRQSDFDTEIKVVMEERRQRTDDNPSVLA
EECEEEHHHHCCHHHCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEE
FERFKWLAYPTSHYRQPVIGYMKNLQNLQLKDLKSWYKNWYVPNNATLIIIGDVDAETTL
EEHHEEEECCHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
NTVKTYFGKIPSARLPPRNDLLEFDRVGYRHMEVHLPVKVPNLFMAWNVRSLVTAKNPQD
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEEEEEEECCCEEEEECHHHHHCCCCCCH
AYALTIIQSLLNGGISSRLQEQLVRKKKILTSVNVSYEPYNRGDSLFTITALPVEGVSLE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHH
DAQKAIQQQIDILKNQPLDPNELERVRANFVSHLVFGQDDIVGQAHLMGNLEVNGLSYRL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECEEECCEEEHH
IDELPTHYGTVKQQDIQRVANAYLVRENLTSLYLLPDSQDKP
HHHCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]