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The map label for this gene is yjeK [H]

Identifier: 50085317

GI number: 50085317

Start: 2176909

End: 2177925

Strand: Direct

Name: yjeK [H]

Synonym: ACIAD2207

Alternate gene names: 50085317

Gene position: 2176909-2177925 (Clockwise)

Preceding gene: 50085309

Following gene: 50085318

Centisome position: 60.49

GC content: 38.54

Gene sequence:

>1017_bases
ATGATAAACTATTTATATCAAGAGCAAAACTGGCAATCGCAACTCAGTGATCTAATCATCGATCCTTTTGAGTTACTTGA
TCAGTTAGACATCTCTTCTGAACAGTTATTATCAGGGGCTATTTTAGCGTCTGACACTTTCAAGCTAAGAGTGCCACGTG
CATTTGTCAATAAAATGCAGAAAGCAGATCCGTTCGATCCTTTACTCTTGCAAGTTCTTCCTCATCATCTCGAACTTGAG
GATCATCCTGAGTTTGTGACCGATCCATTAGGCGAAGAAGAGGCAAACCAGCTTCCAGGCGTGTTACATAAATATCAATC
GCGGTTTTTATTGACCTTAACTGGGGCTTGTGCAGTACATTGTCGCTATTGTTTTCGCCGACACTTTCCTTATCAGGAAA
ATTTGCCTAAGAACAATGATTGGCCTCAAATTCAGAATTATATTCAACAACATCCATTAATCAATGAAGTCATTTTAAGT
GGTGGTGACCCGCTCACCTTGACCAATCATAAGTTAAAAATATGGATCGAAAGACTTGAGTCTCTACCACAAGTTAAAAT
TTTACGGATTCACTCACGCGTACCAATCGTGATTCCCAATCGAATTGATGAGGAACTACTTTCTTTGTTAGAAAACAGTA
GGCTGCGTATAATCATGGTGGTACACTCCAACCATGCTGCTGAATTAGACGACTTTACTTGTAACCAATTACATAAATTA
AGTCTTCGCAATGTGACTGTATTCAATCAAGCAGTTTTACTTAAAGGGGTTAATGATTCAGCACAGACTTTAATCGAATT
AAGTCAACGGTTGTTTGATGCCCGTGTAATGCCCTATTATTTACACGTATTGGATAAAGTAAAAGGCGCACAACATTTTG
ATTTAGAATCATCAAAAGTTGATAGCCTTTATAAAGAAGTTCTGGCGGGGCTTCCAGGCTATCTGGTTCCAAAACTTGTC
AGGGAAATTGCGGGTGAAAAAAATAAAACACCGCTATTTGGCAAACTCACTTTTTAA

Upstream 100 bases:

>100_bases
CTTGAATTCATTTGTAGAATAACTGGCCATGACTGGCACACTCCAAACTTACTAACTTAAATGTATTAATGCTAGACTAG
CATTATTTTTTCCGTGTCGC

Downstream 100 bases:

>100_bases
ATAGAATTTTAATCATCAATGAATAAAGCATTAACAGATATTCTGCACCAGCCGATTAATTTAAATCGCAAAGAGTTGAG
TTTTGCTCACACCAATACAC

Product: aminomutase

Products: (3S)-3,6-diaminohexanoate

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MINYLYQEQNWQSQLSDLIIDPFELLDQLDISSEQLLSGAILASDTFKLRVPRAFVNKMQKADPFDPLLLQVLPHHLELE
DHPEFVTDPLGEEEANQLPGVLHKYQSRFLLTLTGACAVHCRYCFRRHFPYQENLPKNNDWPQIQNYIQQHPLINEVILS
GGDPLTLTNHKLKIWIERLESLPQVKILRIHSRVPIVIPNRIDEELLSLLENSRLRIIMVVHSNHAAELDDFTCNQLHKL
SLRNVTVFNQAVLLKGVNDSAQTLIELSQRLFDARVMPYYLHVLDKVKGAQHFDLESSKVDSLYKEVLAGLPGYLVPKLV
REIAGEKNKTPLFGKLTF

Sequences:

>Translated_338_residues
MINYLYQEQNWQSQLSDLIIDPFELLDQLDISSEQLLSGAILASDTFKLRVPRAFVNKMQKADPFDPLLLQVLPHHLELE
DHPEFVTDPLGEEEANQLPGVLHKYQSRFLLTLTGACAVHCRYCFRRHFPYQENLPKNNDWPQIQNYIQQHPLINEVILS
GGDPLTLTNHKLKIWIERLESLPQVKILRIHSRVPIVIPNRIDEELLSLLENSRLRIIMVVHSNHAAELDDFTCNQLHKL
SLRNVTVFNQAVLLKGVNDSAQTLIELSQRLFDARVMPYYLHVLDKVKGAQHFDLESSKVDSLYKEVLAGLPGYLVPKLV
REIAGEKNKTPLFGKLTF
>Mature_338_residues
MINYLYQEQNWQSQLSDLIIDPFELLDQLDISSEQLLSGAILASDTFKLRVPRAFVNKMQKADPFDPLLLQVLPHHLELE
DHPEFVTDPLGEEEANQLPGVLHKYQSRFLLTLTGACAVHCRYCFRRHFPYQENLPKNNDWPQIQNYIQQHPLINEVILS
GGDPLTLTNHKLKIWIERLESLPQVKILRIHSRVPIVIPNRIDEELLSLLENSRLRIIMVVHSNHAAELDDFTCNQLHKL
SLRNVTVFNQAVLLKGVNDSAQTLIELSQRLFDARVMPYYLHVLDKVKGAQHFDLESSKVDSLYKEVLAGLPGYLVPKLV
REIAGEKNKTPLFGKLTF

Specific function: With YjeA might be involved in the post-translational modification of elongation factor P (EF-P) [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=324, Percent_Identity=50.9259259259259, Blast_Score=329, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022462
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: 5.4.3.2

Molecular weight: Translated: 38932; Mature: 38932

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINYLYQEQNWQSQLSDLIIDPFELLDQLDISSEQLLSGAILASDTFKLRVPRAFVNKMQ
CCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHEECCCEEEECCHHHHHHHH
KADPFDPLLLQVLPHHLELEDHPEFVTDPLGEEEANQLPGVLHKYQSRFLLTLTGACAVH
CCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHH
CRYCFRRHFPYQENLPKNNDWPQIQNYIQQHPLINEVILSGGDPLTLTNHKLKIWIERLE
HHHHHHHCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCEEECCCHHHHHHHHHH
SLPQVKILRIHSRVPIVIPNRIDEELLSLLENSRLRIIMVVHSNHAAELDDFTCNQLHKL
CCCCEEEEEECCCCCEEECCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHH
SLRNVTVFNQAVLLKGVNDSAQTLIELSQRLFDARVMPYYLHVLDKVKGAQHFDLESSKV
HHCCEEHCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DSLYKEVLAGLPGYLVPKLVREIAGEKNKTPLFGKLTF
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MINYLYQEQNWQSQLSDLIIDPFELLDQLDISSEQLLSGAILASDTFKLRVPRAFVNKMQ
CCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHEECCCEEEECCHHHHHHHH
KADPFDPLLLQVLPHHLELEDHPEFVTDPLGEEEANQLPGVLHKYQSRFLLTLTGACAVH
CCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHH
CRYCFRRHFPYQENLPKNNDWPQIQNYIQQHPLINEVILSGGDPLTLTNHKLKIWIERLE
HHHHHHHCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCEEECCCHHHHHHHHHH
SLPQVKILRIHSRVPIVIPNRIDEELLSLLENSRLRIIMVVHSNHAAELDDFTCNQLHKL
CCCCEEEEEECCCCCEEECCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHH
SLRNVTVFNQAVLLKGVNDSAQTLIELSQRLFDARVMPYYLHVLDKVKGAQHFDLESSKV
HHCCEEHCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DSLYKEVLAGLPGYLVPKLVREIAGEKNKTPLFGKLTF
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-lysine

Specific reaction: L-lysine = (3S)-3,6-diaminohexanoate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]