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The map label for this gene is moaE [H]

Identifier: 50085044

GI number: 50085044

Start: 1892848

End: 1893402

Strand: Reverse

Name: moaE [H]

Synonym: ACIAD1904

Alternate gene names: 50085044

Gene position: 1893402-1892848 (Counterclockwise)

Preceding gene: 50085045

Following gene: 50085043

Centisome position: 52.61

GC content: 42.16

Gene sequence:

>555_bases
CTGATTGTACGCTTGTACTTTTATCGCCAGTTGCTGGAGGCTAATATGAAAGAGTTTCAGCGGGTACAGTCAGAAGATTT
AAGTTTAGATTGTTTTGATTCAATTGCAGAGTTTCCAGAATGTGGGGGAATTGGAATCTTTCAGGGAACTGTTAGAAATC
ATCATGAAGGTCGAGCGGTTCAAGCTTTAAAATACACCTCTTATACACCTGTAGCGGAAAAAATGATTCGCCAGATTGAG
CAGGATATTACCCAGAAATATGGCGTATCTTATGTGCGAGTCATTCATCGCATTGGGGCTTTAGATATTGGTGGTACAGC
AATCATTGCCGTGGCTTATGCACCACATCGCCGTGAGGCTTTTCAGGCATGTGAAGAAGCTGTTGAGCGTGTGAAGCACG
AAGTACCCATCTGGAAAGAAGAATTTTATATCGATGGGAGCAGTCAATTTGTAGAAGGCTGTTGTATCCGTAAAGATCAT
AGTCATCCGCATGAGGATACGCCTCATCACCATCATTCAGAACATCATCACAATCACCATAATCATCAGCATTAA

Upstream 100 bases:

>100_bases
GCCAAGATTGTAAATCAGTATCCAGAAGTACAAAAAGCACTTGATCGTTGTGCTTGTGCGATTGGTGAGGATATTATAGC
GCGTCAGACCATATTAAAAA

Downstream 100 bases:

>100_bases
ATCTATTTGCGGGACTCTCCATGAAAAATGTAGGCATGAAACCTGAAAGTTATCGTATTGCCGAAGCTCAAGCCATTTTA
TATGCACCGCCGCATTGTAT

Product: molybdopterin converting factor, large subunit

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIVRLYFYRQLLEANMKEFQRVQSEDLSLDCFDSIAEFPECGGIGIFQGTVRNHHEGRAVQALKYTSYTPVAEKMIRQIE
QDITQKYGVSYVRVIHRIGALDIGGTAIIAVAYAPHRREAFQACEEAVERVKHEVPIWKEEFYIDGSSQFVEGCCIRKDH
SHPHEDTPHHHHSEHHHNHHNHQH

Sequences:

>Translated_184_residues
MIVRLYFYRQLLEANMKEFQRVQSEDLSLDCFDSIAEFPECGGIGIFQGTVRNHHEGRAVQALKYTSYTPVAEKMIRQIE
QDITQKYGVSYVRVIHRIGALDIGGTAIIAVAYAPHRREAFQACEEAVERVKHEVPIWKEEFYIDGSSQFVEGCCIRKDH
SHPHEDTPHHHHSEHHHNHHNHQH
>Mature_184_residues
MIVRLYFYRQLLEANMKEFQRVQSEDLSLDCFDSIAEFPECGGIGIFQGTVRNHHEGRAVQALKYTSYTPVAEKMIRQIE
QDITQKYGVSYVRVIHRIGALDIGGTAIIAVAYAPHRREAFQACEEAVERVKHEVPIWKEEFYIDGSSQFVEGCCIRKDH
SHPHEDTPHHHHSEHHHNHHNHQH

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=137, Percent_Identity=36.4963503649635, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1787003, Length=112, Percent_Identity=33.9285714285714, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17509279, Length=141, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356259, Length=115, Percent_Identity=32.1739130434783, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 21387; Mature: 21387

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRLYFYRQLLEANMKEFQRVQSEDLSLDCFDSIAEFPECGGIGIFQGTVRNHHEGRAV
CEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEECHHHCCCCCHHH
QALKYTSYTPVAEKMIRQIEQDITQKYGVSYVRVIHRIGALDIGGTAIIAVAYAPHRREA
HHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
FQACEEAVERVKHEVPIWKEEFYIDGSSQFVEGCCIRKDHSHPHEDTPHHHHSEHHHNHH
HHHHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCC
NHQH
CCCC
>Mature Secondary Structure
MIVRLYFYRQLLEANMKEFQRVQSEDLSLDCFDSIAEFPECGGIGIFQGTVRNHHEGRAV
CEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEECHHHCCCCCHHH
QALKYTSYTPVAEKMIRQIEQDITQKYGVSYVRVIHRIGALDIGGTAIIAVAYAPHRREA
HHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
FQACEEAVERVKHEVPIWKEEFYIDGSSQFVEGCCIRKDHSHPHEDTPHHHHSEHHHNHH
HHHHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCC
NHQH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]