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The map label for this gene is nahR [H]

Identifier: 50085028

GI number: 50085028

Start: 1879728

End: 1880657

Strand: Direct

Name: nahR [H]

Synonym: ACIAD1887

Alternate gene names: 50085028

Gene position: 1879728-1880657 (Clockwise)

Preceding gene: 50085022

Following gene: 50085033

Centisome position: 52.23

GC content: 32.37

Gene sequence:

>930_bases
ATGAATAATATTCATAATTCAAACAACCAAGACAATCATCTTGACCTTGGCTTATTTCATCGCATTGATATCAATTTATA
TCCACTGTTTGTTGCAATTTTTGAACAAAAAAGTATTTCAAAAACAGCTATAAGCCTTTCGATTAGCCAGTCAGCTGCAA
GCCATGCTTTGCAACGGCTCAGGCTACAATTGGACGATGAAATATTTGTACGACATGGCAATAAGATGTTACCCACACCC
TTTGCACAAAGAATTTATCCAGCTATTAAAAGTGCATTGTTGTCTATTCAAAATATTAATTTACAGAAATATACGTTTGA
TCCAAGCCTGATTCAAAGCTTGAAAATCGCAATTCATGATGAAATTGAACCCATCATTTTTCCTAAAATTATTCGTCATT
TTCAGGAAATAGCGCCAGATATTCAGTTTGCGAGTATTAAACTAGATCGAAAAAAAATTGAGCATGATCTTGCTACTCAA
CAATTGGATTTTGTTATTGATATTAAGCATGATTTAAATAAAGCGATTGGCTTTGATTTTCTGGTTTGTGATCATTATGT
TGTTTGTACACAACAAACTGATCTTTCACAAGAATCGTATCTTGCGGCTTCTCATATTGGCGTGTCATCACGCCGTGCAG
GAGTGCTTTTTGAAGACATATATTTAAATAAAAATAATATATCCAGGCACGTTTTTTTAAGATGTCAAAATTATTCGACC
GCATTGCAAATACTTGAACAAAATCCTACAGCAATGCTAACTATACCAAACAGTATCTTGTCACATTTATCTTATTCGAA
TGCCTTAAATGTATATCAACTGCCGTTTGATTTCCCGGAAATTAATATTGGTATCTTTTCTTTTGCTCATTTATCCAGAA
ATTTAAGATATGATTTTTTGAAAAAAGAAATTATTGCTTTATTTGCTTAG

Upstream 100 bases:

>100_bases
TTCAAACATGATGATTCCTTTAATTCGTTTATCATTTTGCTTTACTTGAACATACGCTCAAATTTATTATGCATGAAATG
ATTTTATCCAATACATCACT

Downstream 100 bases:

>100_bases
GCTATTTGAACAACCGAACGATCGATCAGATTATGCTCGGTTGTTCATGTTTCAGAAATTATTTAAATACTTTGAATCTT
GATGAGTCATCAATATATGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNNIHNSNNQDNHLDLGLFHRIDINLYPLFVAIFEQKSISKTAISLSISQSAASHALQRLRLQLDDEIFVRHGNKMLPTP
FAQRIYPAIKSALLSIQNINLQKYTFDPSLIQSLKIAIHDEIEPIIFPKIIRHFQEIAPDIQFASIKLDRKKIEHDLATQ
QLDFVIDIKHDLNKAIGFDFLVCDHYVVCTQQTDLSQESYLAASHIGVSSRRAGVLFEDIYLNKNNISRHVFLRCQNYST
ALQILEQNPTAMLTIPNSILSHLSYSNALNVYQLPFDFPEINIGIFSFAHLSRNLRYDFLKKEIIALFA

Sequences:

>Translated_309_residues
MNNIHNSNNQDNHLDLGLFHRIDINLYPLFVAIFEQKSISKTAISLSISQSAASHALQRLRLQLDDEIFVRHGNKMLPTP
FAQRIYPAIKSALLSIQNINLQKYTFDPSLIQSLKIAIHDEIEPIIFPKIIRHFQEIAPDIQFASIKLDRKKIEHDLATQ
QLDFVIDIKHDLNKAIGFDFLVCDHYVVCTQQTDLSQESYLAASHIGVSSRRAGVLFEDIYLNKNNISRHVFLRCQNYST
ALQILEQNPTAMLTIPNSILSHLSYSNALNVYQLPFDFPEINIGIFSFAHLSRNLRYDFLKKEIIALFA
>Mature_309_residues
MNNIHNSNNQDNHLDLGLFHRIDINLYPLFVAIFEQKSISKTAISLSISQSAASHALQRLRLQLDDEIFVRHGNKMLPTP
FAQRIYPAIKSALLSIQNINLQKYTFDPSLIQSLKIAIHDEIEPIIFPKIIRHFQEIAPDIQFASIKLDRKKIEHDLATQ
QLDFVIDIKHDLNKAIGFDFLVCDHYVVCTQQTDLSQESYLAASHIGVSSRRAGVLFEDIYLNKNNISRHVFLRCQNYST
ALQILEQNPTAMLTIPNSILSHLSYSNALNVYQLPFDFPEINIGIFSFAHLSRNLRYDFLKKEIIALFA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=167, Percent_Identity=28.1437125748503, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081766, Length=191, Percent_Identity=26.1780104712042, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35459; Mature: 35459

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIHNSNNQDNHLDLGLFHRIDINLYPLFVAIFEQKSISKTAISLSISQSAASHALQRL
CCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
RLQLDDEIFVRHGNKMLPTPFAQRIYPAIKSALLSIQNINLQKYTFDPSLIQSLKIAIHD
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHC
EIEPIIFPKIIRHFQEIAPDIQFASIKLDRKKIEHDLATQQLDFVIDIKHDLNKAIGFDF
CCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHEEEEEEEHHHHHHHHCCEE
LVCDHYVVCTQQTDLSQESYLAASHIGVSSRRAGVLFEDIYLNKNNISRHVFLRCQNYST
EEECCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCHH
ALQILEQNPTAMLTIPNSILSHLSYSNALNVYQLPFDFPEINIGIFSFAHLSRNLRYDFL
HHHHHHCCCCEEEEECHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHHHHHHCCCHHHHH
KKEIIALFA
HHHHHHHCC
>Mature Secondary Structure
MNNIHNSNNQDNHLDLGLFHRIDINLYPLFVAIFEQKSISKTAISLSISQSAASHALQRL
CCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
RLQLDDEIFVRHGNKMLPTPFAQRIYPAIKSALLSIQNINLQKYTFDPSLIQSLKIAIHD
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHC
EIEPIIFPKIIRHFQEIAPDIQFASIKLDRKKIEHDLATQQLDFVIDIKHDLNKAIGFDF
CCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHEEEEEEEHHHHHHHHCCEE
LVCDHYVVCTQQTDLSQESYLAASHIGVSSRRAGVLFEDIYLNKNNISRHVFLRCQNYST
EEECCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCHH
ALQILEQNPTAMLTIPNSILSHLSYSNALNVYQLPFDFPEINIGIFSFAHLSRNLRYDFL
HHHHHHCCCCEEEEECHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHHHHHHCCCHHHHH
KKEIIALFA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]