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The map label for this gene is yqiG [H]

Identifier: 50084981

GI number: 50084981

Start: 1843016

End: 1844167

Strand: Direct

Name: yqiG [H]

Synonym: ACIAD1836

Alternate gene names: 50084981

Gene position: 1843016-1844167 (Clockwise)

Preceding gene: 50084980

Following gene: 50084982

Centisome position: 51.21

GC content: 39.24

Gene sequence:

>1152_bases
ATGACAATTGAATATTCTAAATTATTTGAGTCTTTTGCTTTAACGCCAGACATTGAATTGCGTAACCGAATCATTATGGC
GCCTATGACAACATGGTCAGCCAATCCTGATGGAACTGTATCAGAACAAGAGTTGAATTACATCCGCCAGCGGGTAAATT
GTGTTGGTCTGGTCATTACGGGTTGCACCCATGTACAAGAAAATGGGATTGGCTTTACCAATGAGTTTGCAGCATTTGAT
GATCGCTTTATAGCTAGTCTAAAAGAATTAGCTCAAGCTGCCAAAAGTGGCGGGGCACCAGCAATATTGCAAATTTTCCA
TGCGGGCAATAAAGCGATACCTGATTTAATTCCAAATGCAGATTTGGTTAGCGCGAGTGCATTAATAAAAACACCTACAG
GTTCCTTTGTCGATAGTCAGATGATGACCCGTGCTTTATCACATGAAGAAATTTTAGAGGTTATTCATGCTTTTGGTGAA
ACGACGCGTAGAGCGATAGAAGCTGGGTTTGATGGCATTGAACTGCATGGAGCACATGGTTTTCTCATTCAAAATTTCTT
CTCGCCGTTGTTTAATCAACGTGAAGATGAGTGGGGCGGTTCTTTAGAGAAGCGTATGCGTTTTTCGTTGGAAATCGTAA
AAGAAGTAAAAAGTGTAATTAAACAATATGCTAAAAAGCCATTTGCTTTAGGTTATCGGATCTCTGTTGAAGAATATGAT
GAAAATGGATTGCGAATTGGCGACAGTTTGCAGCTTATTGATCGTTTAATAGACTCAGGTATCGATTATTTGCATGTTTC
ATTAACTGATATTTTGAATAGTAAACCTGTCGATAGCACTGATGAAAAACTGACTATTCAACGTGTTATAGACCATGTGA
ATTATAGAATTTCCTTAATCTCGGCTGGAAAAATTCGGACACCGCATCAAGCGTTACAAGCATTAGCACTTGGACTGCCT
TTAGTCGCAATTGGTAAAGCACTGGTCATCAATCCAGACTGGGTTATATTGGTAGCAAATCATCAGGCCGATCAGATTTC
CACAGAATTAGAGCTTGAAAAAGATGCTGAATTACACATTCCAGATCATTTATGGGATGAAATCAAGATAAGAAAGGGAT
GGTTTCCTATGCGACAAATAGAGCAGGTCTAA

Upstream 100 bases:

>100_bases
ATCTCAGCAGAATAGGCAAATAACTTTTCAGTTTAGGCAATTTGCATCAATCCTCTCAATTTATACTTTTTCTTAGAAAA
TATTTTTATGAGATGAATTC

Downstream 100 bases:

>100_bases
TCCTGCTTTAAATAATAGAGGTACTATTATGATTGGTGATGAAAATACGCAAGATATCATTACGTCACTTGCTCATACTG
TTGATCGGTTAATTCAGGTC

Product: oxidoreductase (NADH-dependent flavin oxidoreductase)

Products: NADP; Cytotoxic compound [C]

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTIEYSKLFESFALTPDIELRNRIIMAPMTTWSANPDGTVSEQELNYIRQRVNCVGLVITGCTHVQENGIGFTNEFAAFD
DRFIASLKELAQAAKSGGAPAILQIFHAGNKAIPDLIPNADLVSASALIKTPTGSFVDSQMMTRALSHEEILEVIHAFGE
TTRRAIEAGFDGIELHGAHGFLIQNFFSPLFNQREDEWGGSLEKRMRFSLEIVKEVKSVIKQYAKKPFALGYRISVEEYD
ENGLRIGDSLQLIDRLIDSGIDYLHVSLTDILNSKPVDSTDEKLTIQRVIDHVNYRISLISAGKIRTPHQALQALALGLP
LVAIGKALVINPDWVILVANHQADQISTELELEKDAELHIPDHLWDEIKIRKGWFPMRQIEQV

Sequences:

>Translated_383_residues
MTIEYSKLFESFALTPDIELRNRIIMAPMTTWSANPDGTVSEQELNYIRQRVNCVGLVITGCTHVQENGIGFTNEFAAFD
DRFIASLKELAQAAKSGGAPAILQIFHAGNKAIPDLIPNADLVSASALIKTPTGSFVDSQMMTRALSHEEILEVIHAFGE
TTRRAIEAGFDGIELHGAHGFLIQNFFSPLFNQREDEWGGSLEKRMRFSLEIVKEVKSVIKQYAKKPFALGYRISVEEYD
ENGLRIGDSLQLIDRLIDSGIDYLHVSLTDILNSKPVDSTDEKLTIQRVIDHVNYRISLISAGKIRTPHQALQALALGLP
LVAIGKALVINPDWVILVANHQADQISTELELEKDAELHIPDHLWDEIKIRKGWFPMRQIEQV
>Mature_382_residues
TIEYSKLFESFALTPDIELRNRIIMAPMTTWSANPDGTVSEQELNYIRQRVNCVGLVITGCTHVQENGIGFTNEFAAFDD
RFIASLKELAQAAKSGGAPAILQIFHAGNKAIPDLIPNADLVSASALIKTPTGSFVDSQMMTRALSHEEILEVIHAFGET
TRRAIEAGFDGIELHGAHGFLIQNFFSPLFNQREDEWGGSLEKRMRFSLEIVKEVKSVIKQYAKKPFALGYRISVEEYDE
NGLRIGDSLQLIDRLIDSGIDYLHVSLTDILNSKPVDSTDEKLTIQRVIDHVNYRISLISAGKIRTPHQALQALALGLPL
VAIGKALVINPDWVILVANHQADQISTELELEKDAELHIPDHLWDEIKIRKGWFPMRQIEQV

Specific function: Unknown

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=334, Percent_Identity=31.1377245508982, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1789463, Length=356, Percent_Identity=27.5280898876405, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17540738, Length=263, Percent_Identity=31.1787072243346, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=177, Percent_Identity=34.4632768361582, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=178, Percent_Identity=34.8314606741573, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559804, Length=178, Percent_Identity=33.1460674157303, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17559802, Length=262, Percent_Identity=28.6259541984733, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=183, Percent_Identity=31.6939890710383, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=336, Percent_Identity=27.3809523809524, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=246, Percent_Identity=26.8292682926829, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=229, Percent_Identity=27.5109170305677, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42839; Mature: 42707

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEYSKLFESFALTPDIELRNRIIMAPMTTWSANPDGTVSEQELNYIRQRVNCVGLVIT
CCCCHHHHHHHHCCCCCHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEEEE
GCTHVQENGIGFTNEFAAFDDRFIASLKELAQAAKSGGAPAILQIFHAGNKAIPDLIPNA
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
DLVSASALIKTPTGSFVDSQMMTRALSHEEILEVIHAFGETTRRAIEAGFDGIELHGAHG
CHHCCHHEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCH
FLIQNFFSPLFNQREDEWGGSLEKRMRFSLEIVKEVKSVIKQYAKKPFALGYRISVEEYD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECC
ENGLRIGDSLQLIDRLIDSGIDYLHVSLTDILNSKPVDSTDEKLTIQRVIDHVNYRISLI
CCCCEECHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEE
SAGKIRTPHQALQALALGLPLVAIGKALVINPDWVILVANHQADQISTELELEKDAELHI
ECCCCCCHHHHHHHHHHCCCHHHHCCEEEECCCEEEEEECCCHHHHHHHEEECCCCCEEC
PDHLWDEIKIRKGWFPMRQIEQV
CHHHHHHHEEECCCCCHHHHHCC
>Mature Secondary Structure 
TIEYSKLFESFALTPDIELRNRIIMAPMTTWSANPDGTVSEQELNYIRQRVNCVGLVIT
CCCHHHHHHHHCCCCCHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEEEE
GCTHVQENGIGFTNEFAAFDDRFIASLKELAQAAKSGGAPAILQIFHAGNKAIPDLIPNA
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
DLVSASALIKTPTGSFVDSQMMTRALSHEEILEVIHAFGETTRRAIEAGFDGIELHGAHG
CHHCCHHEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCH
FLIQNFFSPLFNQREDEWGGSLEKRMRFSLEIVKEVKSVIKQYAKKPFALGYRISVEEYD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECC
ENGLRIGDSLQLIDRLIDSGIDYLHVSLTDILNSKPVDSTDEKLTIQRVIDHVNYRISLI
CCCCEECHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEE
SAGKIRTPHQALQALALGLPLVAIGKALVINPDWVILVANHQADQISTELELEKDAELHI
ECCCCCCHHHHHHHHHHCCCHHHHCCEEEECCCEEEEEECCCHHHHHHHEEECCCCCEEC
PDHLWDEIKIRKGWFPMRQIEQV
CHHHHHHHEEECCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; N-ethylmaleimide [C]

Specific reaction: NADPH + N-ethylmaleimide = NADP + Cytotoxic compound [C]

General reaction: Reduction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]