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The map label for this gene is benK [H]

Identifier: 50084962

GI number: 50084962

Start: 1821361

End: 1822713

Strand: Direct

Name: benK [H]

Synonym: ACIAD1815

Alternate gene names: 50084962

Gene position: 1821361-1822713 (Clockwise)

Preceding gene: 50084961

Following gene: 50084964

Centisome position: 50.61

GC content: 43.98

Gene sequence:

>1353_bases
ATGTCAACAATGAGTTTAAATATTAACGATCTGCTCAATCAGGCAAAATTTTCAAAATTTCATTTGAGTGTGGTGTTTTG
GTGCACTCTCATTAATATCTGTGATGGTTACGATCTGGTGATCTATGGCGTGGTTTTACCTCGGCTTATGGAGCAATGGT
CACTCACTTCAGTTCAAGCTGGTATGCTGGCCAGTACCGCCATGTGTGGCATGCTGGTGGGTGCATTAAGTTGTGGTATT
TTGGCAGACAAGTTTGGTCGAAAGCGTGTGCTGCTGCTGTGTGTATTTTTTCTCAGCACGTTTACATTATTGGGTAGTTT
TGCATCCACCCCAACCGAATTTGCCATTTTAAGATTTCTGGCTGGACTGGGAATTGGCGGCGCCATGCCGAATGTAGTGG
CACTGACTTCTGAATATTCTCCCAAAAAATCGCGTGTCACGATGGTCAGTATCATGTCGTGTGGATATGCGGTGGGCGCC
ATAATTTCAGCATTGGTCGGTTCAATTCTGGTTGAGCGCTTTGGCTGGCAAATTATGTTTATATTGGCGGGTATTCCCTT
GTTGTTTATTCCGATCATATGGAAGTATTTGCCCGAGTCACTGGTGTTTAATGTCAAAAAGAACAATACCGAAAAGGCAC
ACGCATTAATTGCAAAAGTCGATCCAACGGTTCTTGTAAGCCAGCACACCAAGCTGGTTTTAAATGAATCTTTAGAAAAA
GCCTATGGATCACGTCGAGTTTTATTTCAAGAGGGACGCGCCGCAGGAACACTTAAATTCTGGATCGCATTTTTTATGTG
CTTATTGGTGGTTTATGCGCTCAGCAGTTGGTTACCAAAGCTGATGTACAATGCTGGCTATCCATTGGGCAAAAGCATTC
TGTTTTTGTTAGCGATGAATGTGGGTGGAATTATTGGCGGAACAACCAGCGGTATGTTGGCAGATAAATTTAAGATCAAA
CCAGTGGTGATTAGTTTGTTCTGTATTGCGGCTCTGTCACTGATTGCGCTGGGTTTTAACACATCAGCCATTATTCTGTA
TACCTTGGTTGCGGTGGCAGGTGCATCCATTCAAGGCGCTTCGATTTTACTTTATAGTTATGTGGCACAGTTTTATCCAC
TGGTGGCAAATTCAACAGGCATTGGCTGGGCCTCTGCAATTGGTCGTACAGGTGCCATCATGGGGCCAATTCTGGCTGGT
ATGCTGCTGGTATTGAATCTACCGCATTTGATGAACTTTGTACTGATTAGCGTTCCCGCTTTGATTGCTGCAATCTCAAT
CGGCTTTTTGACGACAAGCAAGAAAAAAGTGGAGCAGCCTGTTGCTCTCGTTACTCAGCAATCGCTTGAATAA

Upstream 100 bases:

>100_bases
TAGCATCAAAATCTAGCATATAAAAATTGATGAAAAACAAGACAAAACCCTATTTGCACATGATAAAGCGTCCCAAATGT
TTTCACATTGGAGGTGAAAA

Downstream 100 bases:

>100_bases
TACAAAAACGTTTAAATAAAAAAGCTGAAGACGACTTCAGCTTTTTTATTTTGAATTAAAATACATGATAAATCGGATCA
TCTGGCCACTGCCCACCAAT

Product: MFS superfamily benzoate transport protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSTMSLNINDLLNQAKFSKFHLSVVFWCTLINICDGYDLVIYGVVLPRLMEQWSLTSVQAGMLASTAMCGMLVGALSCGI
LADKFGRKRVLLLCVFFLSTFTLLGSFASTPTEFAILRFLAGLGIGGAMPNVVALTSEYSPKKSRVTMVSIMSCGYAVGA
IISALVGSILVERFGWQIMFILAGIPLLFIPIIWKYLPESLVFNVKKNNTEKAHALIAKVDPTVLVSQHTKLVLNESLEK
AYGSRRVLFQEGRAAGTLKFWIAFFMCLLVVYALSSWLPKLMYNAGYPLGKSILFLLAMNVGGIIGGTTSGMLADKFKIK
PVVISLFCIAALSLIALGFNTSAIILYTLVAVAGASIQGASILLYSYVAQFYPLVANSTGIGWASAIGRTGAIMGPILAG
MLLVLNLPHLMNFVLISVPALIAAISIGFLTTSKKKVEQPVALVTQQSLE

Sequences:

>Translated_450_residues
MSTMSLNINDLLNQAKFSKFHLSVVFWCTLINICDGYDLVIYGVVLPRLMEQWSLTSVQAGMLASTAMCGMLVGALSCGI
LADKFGRKRVLLLCVFFLSTFTLLGSFASTPTEFAILRFLAGLGIGGAMPNVVALTSEYSPKKSRVTMVSIMSCGYAVGA
IISALVGSILVERFGWQIMFILAGIPLLFIPIIWKYLPESLVFNVKKNNTEKAHALIAKVDPTVLVSQHTKLVLNESLEK
AYGSRRVLFQEGRAAGTLKFWIAFFMCLLVVYALSSWLPKLMYNAGYPLGKSILFLLAMNVGGIIGGTTSGMLADKFKIK
PVVISLFCIAALSLIALGFNTSAIILYTLVAVAGASIQGASILLYSYVAQFYPLVANSTGIGWASAIGRTGAIMGPILAG
MLLVLNLPHLMNFVLISVPALIAAISIGFLTTSKKKVEQPVALVTQQSLE
>Mature_449_residues
STMSLNINDLLNQAKFSKFHLSVVFWCTLINICDGYDLVIYGVVLPRLMEQWSLTSVQAGMLASTAMCGMLVGALSCGIL
ADKFGRKRVLLLCVFFLSTFTLLGSFASTPTEFAILRFLAGLGIGGAMPNVVALTSEYSPKKSRVTMVSIMSCGYAVGAI
ISALVGSILVERFGWQIMFILAGIPLLFIPIIWKYLPESLVFNVKKNNTEKAHALIAKVDPTVLVSQHTKLVLNESLEKA
YGSRRVLFQEGRAAGTLKFWIAFFMCLLVVYALSSWLPKLMYNAGYPLGKSILFLLAMNVGGIIGGTTSGMLADKFKIKP
VVISLFCIAALSLIALGFNTSAIILYTLVAVAGASIQGASILLYSYVAQFYPLVANSTGIGWASAIGRTGAIMGPILAGM
LLVLNLPHLMNFVLISVPALIAAISIGFLTTSKKKVEQPVALVTQQSLE

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=459, Percent_Identity=25.4901960784314, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI213021148, Length=434, Percent_Identity=23.2718894009217, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI7662270, Length=233, Percent_Identity=25.7510729613734, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI216548223, Length=239, Percent_Identity=25.1046025104602, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI262399383, Length=174, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI73695465, Length=288, Percent_Identity=24.6527777777778, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI8923870, Length=380, Percent_Identity=24.7368421052632, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI166197673, Length=398, Percent_Identity=25.1256281407035, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081723, Length=418, Percent_Identity=31.8181818181818, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI87082159, Length=400, Percent_Identity=24.5, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786229, Length=404, Percent_Identity=24.5049504950495, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082231, Length=215, Percent_Identity=29.7674418604651, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788068, Length=453, Percent_Identity=22.9580573951435, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082404, Length=380, Percent_Identity=21.8421052631579, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788074, Length=365, Percent_Identity=23.2876712328767, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790550, Length=360, Percent_Identity=25.5555555555556, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=466, Percent_Identity=24.2489270386266, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32564663, Length=425, Percent_Identity=24, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17560496, Length=408, Percent_Identity=24.2647058823529, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320595, Length=181, Percent_Identity=29.8342541436464, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922874, Length=423, Percent_Identity=22.4586288416076, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24640198, Length=211, Percent_Identity=27.9620853080569, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24640196, Length=211, Percent_Identity=27.9620853080569, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24640200, Length=211, Percent_Identity=27.9620853080569, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19922616, Length=368, Percent_Identity=24.7282608695652, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI62484254, Length=388, Percent_Identity=22.9381443298969, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48416; Mature: 48285

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMSLNINDLLNQAKFSKFHLSVVFWCTLINICDGYDLVIYGVVLPRLMEQWSLTSVQA
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHH
GMLASTAMCGMLVGALSCGILADKFGRKRVLLLCVFFLSTFTLLGSFASTPTEFAILRFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGLGIGGAMPNVVALTSEYSPKKSRVTMVSIMSCGYAVGAIISALVGSILVERFGWQIMF
HHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
ILAGIPLLFIPIIWKYLPESLVFNVKKNNTEKAHALIAKVDPTVLVSQHTKLVLNESLEK
HHHHHHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHH
AYGSRRVLFQEGRAAGTLKFWIAFFMCLLVVYALSSWLPKLMYNAGYPLGKSILFLLAMN
HHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VGGIIGGTTSGMLADKFKIKPVVISLFCIAALSLIALGFNTSAIILYTLVAVAGASIQGA
CCCEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCH
SILLYSYVAQFYPLVANSTGIGWASAIGRTGAIMGPILAGMLLVLNLPHLMNFVLISVPA
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LIAAISIGFLTTSKKKVEQPVALVTQQSLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STMSLNINDLLNQAKFSKFHLSVVFWCTLINICDGYDLVIYGVVLPRLMEQWSLTSVQA
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHH
GMLASTAMCGMLVGALSCGILADKFGRKRVLLLCVFFLSTFTLLGSFASTPTEFAILRFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGLGIGGAMPNVVALTSEYSPKKSRVTMVSIMSCGYAVGAIISALVGSILVERFGWQIMF
HHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
ILAGIPLLFIPIIWKYLPESLVFNVKKNNTEKAHALIAKVDPTVLVSQHTKLVLNESLEK
HHHHHHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHH
AYGSRRVLFQEGRAAGTLKFWIAFFMCLLVVYALSSWLPKLMYNAGYPLGKSILFLLAMN
HHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VGGIIGGTTSGMLADKFKIKPVVISLFCIAALSLIALGFNTSAIILYTLVAVAGASIQGA
CCCEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCH
SILLYSYVAQFYPLVANSTGIGWASAIGRTGAIMGPILAGMLLVLNLPHLMNFVLISVPA
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LIAAISIGFLTTSKKKVEQPVALVTQQSLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]