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The map label for this gene is yetM [H]

Identifier: 50084955

GI number: 50084955

Start: 1814916

End: 1816058

Strand: Direct

Name: yetM [H]

Synonym: ACIAD1808

Alternate gene names: 50084955

Gene position: 1814916-1816058 (Clockwise)

Preceding gene: 50084954

Following gene: 50084956

Centisome position: 50.43

GC content: 39.63

Gene sequence:

>1143_bases
ATGACAGGGATCGTAGATATTGCCATTGTTGGTGGTGGCATAGGTGGCATGTGTGCAGCCATCCAACTCAAGAAGCTTGG
AAAAAACGTATCTTTAATTGAAATTAAAGATACGCTCAAGCCAATAGGCGCTGGTATTACCTTAAGTGCAGCAACACTTC
GCGCACTTAAAGAAATTGGGGTAGTGCAACAGTTATTTGAAGTGTCTGGACAGTTTTCACAATTTGATATGTACACGTCA
GATGGACATAAGGTTGCGGAAACACCAATTAAGCCAGCAGTTGGTGCGGAAGATCTGGTTGCAAATAGTATTGGTGTGAT
ACGTACCAAATTTGCAGAAGTGCTGGAAAATAAATTACGTGAGTTAGGTGTAAACGTTATTTTAGGTACTACTGTCGATA
AATTGGAAAATAACCAAGATTCCATCAAGATCCTATTCACCAATGGCCATGAACAACAATTTGACTTAGTGATCGGAGCA
GATGGTATACATTCAAAAATACGCCATCTTGTCTTTCCCGAACTTGCTGAAAGTACCTTTACCCACCAAGGGGCATGGCG
AATTATTGCACCAAAATATTTTGATAACTTTTCAATGCTGATTGGTAAAACGCTTAAAGCTTCCTTTAGTCCAATTAGTG
ATTCACAAAGTTATATGTGCGTACTAGATCATCGTGAGAATGATGATTTTATTGAACCGCATTTATGGCCTGCAAAACTC
TCCAATTTATTAGCCGAATTTGGTAGCGTTGTTCAAGAAGTAAAAGCTGATATCGATCAAGGAAAAATTAAAGCGGAAGA
TATTCTTTACCGTCCATTACATACCTTACTGGTCAAAGAATCTTGGCATAAAGGTCGTGTTGTTTTATTGGGTGATGCAG
TACATGCAACGACGCCACATCTTGCTTCAGGTGCAGGCCTCGCAATTGAGGGGGCGATACTTTTAAGTGAAGAATTAGCA
AAAGATCAACCCTTAGAACATGCTTTGACTCACTATCAAGCACGACATTTTGATCGAGCAAAAATGGTGATCGATGTCTC
GACTCGTCTAGGTGAAATTGAAATGAGTAATGGTTCATCTGTCGAACATAAAGAACTTGCCTCTAAAGCATTTGAAATTT
TGACACAGCCACTTAAGGCCTAA

Upstream 100 bases:

>100_bases
ACAGTTCAATTGATAATCCACTGAATGCTGGAGCGTATATTGCAGATTGGTTGGCAGAACATTTAAACGGAAAAACTTCA
AAGTAAACTGGAGAAACAAG

Downstream 100 bases:

>100_bases
TACTTAAAACTAGCCCAAAGAAGAGTCGAGAGCTTTGGGCTAAATTTTTGCAATAATATAGAGGTGAAATATGAAGTTTG
CCACAATAAAAAATGGGACT

Product: hypothetical protein

Products: H2O; 3-(2,3-dihydroxyphenyl)propionate; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTGIVDIAIVGGGIGGMCAAIQLKKLGKNVSLIEIKDTLKPIGAGITLSAATLRALKEIGVVQQLFEVSGQFSQFDMYTS
DGHKVAETPIKPAVGAEDLVANSIGVIRTKFAEVLENKLRELGVNVILGTTVDKLENNQDSIKILFTNGHEQQFDLVIGA
DGIHSKIRHLVFPELAESTFTHQGAWRIIAPKYFDNFSMLIGKTLKASFSPISDSQSYMCVLDHRENDDFIEPHLWPAKL
SNLLAEFGSVVQEVKADIDQGKIKAEDILYRPLHTLLVKESWHKGRVVLLGDAVHATTPHLASGAGLAIEGAILLSEELA
KDQPLEHALTHYQARHFDRAKMVIDVSTRLGEIEMSNGSSVEHKELASKAFEILTQPLKA

Sequences:

>Translated_380_residues
MTGIVDIAIVGGGIGGMCAAIQLKKLGKNVSLIEIKDTLKPIGAGITLSAATLRALKEIGVVQQLFEVSGQFSQFDMYTS
DGHKVAETPIKPAVGAEDLVANSIGVIRTKFAEVLENKLRELGVNVILGTTVDKLENNQDSIKILFTNGHEQQFDLVIGA
DGIHSKIRHLVFPELAESTFTHQGAWRIIAPKYFDNFSMLIGKTLKASFSPISDSQSYMCVLDHRENDDFIEPHLWPAKL
SNLLAEFGSVVQEVKADIDQGKIKAEDILYRPLHTLLVKESWHKGRVVLLGDAVHATTPHLASGAGLAIEGAILLSEELA
KDQPLEHALTHYQARHFDRAKMVIDVSTRLGEIEMSNGSSVEHKELASKAFEILTQPLKA
>Mature_379_residues
TGIVDIAIVGGGIGGMCAAIQLKKLGKNVSLIEIKDTLKPIGAGITLSAATLRALKEIGVVQQLFEVSGQFSQFDMYTSD
GHKVAETPIKPAVGAEDLVANSIGVIRTKFAEVLENKLRELGVNVILGTTVDKLENNQDSIKILFTNGHEQQFDLVIGAD
GIHSKIRHLVFPELAESTFTHQGAWRIIAPKYFDNFSMLIGKTLKASFSPISDSQSYMCVLDHRENDDFIEPHLWPAKLS
NLLAEFGSVVQEVKADIDQGKIKAEDILYRPLHTLLVKESWHKGRVVLLGDAVHATTPHLASGAGLAIEGAILLSEELAK
DQPLEHALTHYQARHFDRAKMVIDVSTRLGEIEMSNGSSVEHKELASKAFEILTQPLKA

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 41483; Mature: 41352

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGIVDIAIVGGGIGGMCAAIQLKKLGKNVSLIEIKDTLKPIGAGITLSAATLRALKEIG
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCEEHHHHHHHHHHHH
VVQQLFEVSGQFSQFDMYTSDGHKVAETPIKPAVGAEDLVANSIGVIRTKFAEVLENKLR
HHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELGVNVILGTTVDKLENNQDSIKILFTNGHEQQFDLVIGADGIHSKIRHLVFPELAESTF
HCCCEEEEECCHHHHCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
THQGAWRIIAPKYFDNFSMLIGKTLKASFSPISDSQSYMCVLDHRENDDFIEPHLWPAKL
CCCCCEEEECCHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHH
SNLLAEFGSVVQEVKADIDQGKIKAEDILYRPLHTLLVKESWHKGRVVLLGDAVHATTPH
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHCCCCC
LASGAGLAIEGAILLSEELAKDQPLEHALTHYQARHFDRAKMVIDVSTRLGEIEMSNGSS
CCCCCCCEEEHHEEEHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
VEHKELASKAFEILTQPLKA
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGIVDIAIVGGGIGGMCAAIQLKKLGKNVSLIEIKDTLKPIGAGITLSAATLRALKEIG
CCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCEEHHHHHHHHHHHH
VVQQLFEVSGQFSQFDMYTSDGHKVAETPIKPAVGAEDLVANSIGVIRTKFAEVLENKLR
HHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELGVNVILGTTVDKLENNQDSIKILFTNGHEQQFDLVIGADGIHSKIRHLVFPELAESTF
HCCCEEEEECCHHHHCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
THQGAWRIIAPKYFDNFSMLIGKTLKASFSPISDSQSYMCVLDHRENDDFIEPHLWPAKL
CCCCCEEEECCHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHH
SNLLAEFGSVVQEVKADIDQGKIKAEDILYRPLHTLLVKESWHKGRVVLLGDAVHATTPH
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHCCCCC
LASGAGLAIEGAILLSEELAKDQPLEHALTHYQARHFDRAKMVIDVSTRLGEIEMSNGSS
CCCCCCCEEEHHEEEHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
VEHKELASKAFEILTQPLKA
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(3-hydroxyphenyl)propionate; NADH; O2 [C]

Specific reaction: 3-(3-hydroxyphenyl)propionate + NADH + O2 = H2O + 3-(2,3-dihydroxyphenyl)propionate + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]