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The map label for this gene is qseD [H]

Identifier: 50084897

GI number: 50084897

Start: 1753787

End: 1754677

Strand: Direct

Name: qseD [H]

Synonym: ACIAD1745

Alternate gene names: 50084897

Gene position: 1753787-1754677 (Clockwise)

Preceding gene: 50084888

Following gene: 50084898

Centisome position: 48.73

GC content: 31.09

Gene sequence:

>891_bases
ATGAGTCTTGAAATTCGCTGGATTGAAGATCTACTCACACTCGAACAAGAACGTTCATTTTCAAAAGCTGCAGAGCGACG
CTTTGTCAGTCAGTCCGCTTTTACAAGACGCATTCAACAGCTAGAGCAATCTTTGGGTTATCCCATTTTGGAGCGAAACT
CGCGTTATATGGAGTTTACCGATGCGGGTCAGATATTATTGACGACAGCCAAAAGTATTGAACAACAATTGAATGCAACT
TTGGCTTTATTAAATAATTTAAATCGTGCAAATGAAGTGACCATCAAATTTGCAGTCGTTCATTCATTAAGTTCTACTTT
TTTTTCAAAGTTTTTAAAATTATTCCCCGAATATATTAAAGATTTTAAAATAGAATTGGTTGCTGCCAACGTGGGTGAGG
GGTTTAAACTTTTAAAAGAAGGGGCTTGTGATTTCTTGATTTGTTATTCAGATGAATCCAAATTGAAATTAATTAATCAT
GAAGTACTTAGTTATTTAAAGCTTGGTGAAACAGAAATTATTCCTGTTACACTTATTGATGAAGATGGAAATGCAAAATA
TGATTTAAATCAAAGATTTCCATTGTTATCTTACAGTAAAAATGCGTACTTAAGAAATCTGGTTGATCAGGTTATTGTAA
ATAGATTAGATTATCGAATTTTATATGAAACAGATCATGCAAATAATCTTAAGGATTTCGTATTGCAAGGTGCAGGAATT
GCTTGGTTGCCTAAAATTACGATTGAAGAAGATTTGTTAAGAAAAAGGTTAAAAATTATTAATGCGCGTGAATTTATTAT
TAAGCAGCAAATTTTTATATTTAAAAATAAGTTAAGAAAAGATGATTATTTGAAAATATTTTGGGATTCTCTTAGAAATA
TCGAATACTAA

Upstream 100 bases:

>100_bases
GAATTGGGTTTGCATGATTTCTAATGCATAGATTAATTTTAGTATGCATTTTTTGCATACCGTGTTTATAATGCGCCAAA
ACACTATATGACATGAAGCA

Downstream 100 bases:

>100_bases
AATAATAGCAAATTTTTGAAAAAGCCCAATTCATTTACAATGGTGAGTTTAAGCTTTCTGGATAAAAAATCTGCGTTAAA
AAAGCATTTATGTTATTTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSLEIRWIEDLLTLEQERSFSKAAERRFVSQSAFTRRIQQLEQSLGYPILERNSRYMEFTDAGQILLTTAKSIEQQLNAT
LALLNNLNRANEVTIKFAVVHSLSSTFFSKFLKLFPEYIKDFKIELVAANVGEGFKLLKEGACDFLICYSDESKLKLINH
EVLSYLKLGETEIIPVTLIDEDGNAKYDLNQRFPLLSYSKNAYLRNLVDQVIVNRLDYRILYETDHANNLKDFVLQGAGI
AWLPKITIEEDLLRKRLKIINAREFIIKQQIFIFKNKLRKDDYLKIFWDSLRNIEY

Sequences:

>Translated_296_residues
MSLEIRWIEDLLTLEQERSFSKAAERRFVSQSAFTRRIQQLEQSLGYPILERNSRYMEFTDAGQILLTTAKSIEQQLNAT
LALLNNLNRANEVTIKFAVVHSLSSTFFSKFLKLFPEYIKDFKIELVAANVGEGFKLLKEGACDFLICYSDESKLKLINH
EVLSYLKLGETEIIPVTLIDEDGNAKYDLNQRFPLLSYSKNAYLRNLVDQVIVNRLDYRILYETDHANNLKDFVLQGAGI
AWLPKITIEEDLLRKRLKIINAREFIIKQQIFIFKNKLRKDDYLKIFWDSLRNIEY
>Mature_295_residues
SLEIRWIEDLLTLEQERSFSKAAERRFVSQSAFTRRIQQLEQSLGYPILERNSRYMEFTDAGQILLTTAKSIEQQLNATL
ALLNNLNRANEVTIKFAVVHSLSSTFFSKFLKLFPEYIKDFKIELVAANVGEGFKLLKEGACDFLICYSDESKLKLINHE
VLSYLKLGETEIIPVTLIDEDGNAKYDLNQRFPLLSYSKNAYLRNLVDQVIVNRLDYRILYETDHANNLKDFVLQGAGIA
WLPKITIEEDLLRKRLKIINAREFIIKQQIFIFKNKLRKDDYLKIFWDSLRNIEY

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=297, Percent_Identity=31.986531986532, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI157672245, Length=110, Percent_Identity=30.9090909090909, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=236, Percent_Identity=24.5762711864407, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34653; Mature: 34522

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEIRWIEDLLTLEQERSFSKAAERRFVSQSAFTRRIQQLEQSLGYPILERNSRYMEFT
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEC
DAGQILLTTAKSIEQQLNATLALLNNLNRANEVTIKFAVVHSLSSTFFSKFLKLFPEYIK
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DFKIELVAANVGEGFKLLKEGACDFLICYSDESKLKLINHEVLSYLKLGETEIIPVTLID
HHEEEEEEECCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEE
EDGNAKYDLNQRFPLLSYSKNAYLRNLVDQVIVNRLDYRILYETDHANNLKDFVLQGAGI
CCCCCEEECCCCCCCEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCCCE
AWLPKITIEEDLLRKRLKIINAREFIIKQQIFIFKNKLRKDDYLKIFWDSLRNIEY
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLEIRWIEDLLTLEQERSFSKAAERRFVSQSAFTRRIQQLEQSLGYPILERNSRYMEFT
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEC
DAGQILLTTAKSIEQQLNATLALLNNLNRANEVTIKFAVVHSLSSTFFSKFLKLFPEYIK
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DFKIELVAANVGEGFKLLKEGACDFLICYSDESKLKLINHEVLSYLKLGETEIIPVTLID
HHEEEEEEECCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEE
EDGNAKYDLNQRFPLLSYSKNAYLRNLVDQVIVNRLDYRILYETDHANNLKDFVLQGAGI
CCCCCEEECCCCCCCEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCCCE
AWLPKITIEEDLLRKRLKIINAREFIIKQQIFIFKNKLRKDDYLKIFWDSLRNIEY
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]