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The map label for this gene is blh [H]

Identifier: 50084835

GI number: 50084835

Start: 1682629

End: 1683507

Strand: Direct

Name: blh [H]

Synonym: ACIAD1678

Alternate gene names: 50084835

Gene position: 1682629-1683507 (Clockwise)

Preceding gene: 50084834

Following gene: 50084836

Centisome position: 46.76

GC content: 35.38

Gene sequence:

>879_bases
ATGTCTCAACAACAACCCAATGTTCAAGAATTTTTTGACTTGGAGACCAATACCTTTAGTTATGTGGTTACAGATATTCA
AACACAAAAATGTGCCATCATCGATAGTGTGCTAGATTATGATGTAGCTTCAGCGACTACTTCTACAGATCAGGCTGATA
AAATCATTGCTTATATACGCCAAAATAGCCTAAGCGTTGCATGGATATTAGAAACACATGTGCATGCCGATCACCTCACA
GCTTCACAATATTTAAAAAAACAATTAGGTGGCAAAATTGCCATGAGTCGTAAAATCGCTATTGTTCAAGAAACCTTTAG
TCAAATTTATAATCTGGATATGAAATACTTTAATTTACATCAGAGTTTTGATTATTTATTTGAAGACAATGAACATTTTA
AAATAGGTGATCTTGATGCTTATAACATTCCAACGCCAGGTCATACCCCAGCTTGTTTAAGCTATGTGGTGGGTGATGCT
GTGTTTGTTGGAGACACACTTTTTATGCCAGATTATGGTACAGCACGTTGTGATTTTCCAAAAGGAAGTGCATCCATCTT
ATTTGATTCGGTACAACGCTTATATAATTTACCAGACACTACACGAATGTTTTTATGTCATGACTATTTACCCAGTACGC
GTGATGATTATGTATGTGAAACAGATATCTATACTCAAAAGTCTTGCAATATTCATATCCATGAAGGAATGTCTAAACTG
GAATTTGTTGAAATGCGTCAGGCCAGAGATGCAACGCTTACTATGCCAAAACTAATATTACCAGCCATTCAGATTAATAT
GGATGCTGGAAAATTTCCTGAACCAGAATCGAATGGGCAAAGCTATTTAAAATTACCGCTGAATTACTTTAAAGCTTAA

Upstream 100 bases:

>100_bases
TTGACTTTAATCGGGCTAGGCAGTTATCAGGCATTTTATTTTATTTTTGCCATGTTGATTGGTATGTTGATCTATCGCAA
ATGGTCAGGAGCATAAAATC

Downstream 100 bases:

>100_bases
GAATATGTCAAATTTAGAAGATCCAAGAGTACTACTTGCACTTGAGCGTACTTTACTTGCCTGGAATAGAAGTAGTCTCG
CTTTGATTGCTTTTGGTTTT

Product: metallo-beta lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSQQQPNVQEFFDLETNTFSYVVTDIQTQKCAIIDSVLDYDVASATTSTDQADKIIAYIRQNSLSVAWILETHVHADHLT
ASQYLKKQLGGKIAMSRKIAIVQETFSQIYNLDMKYFNLHQSFDYLFEDNEHFKIGDLDAYNIPTPGHTPACLSYVVGDA
VFVGDTLFMPDYGTARCDFPKGSASILFDSVQRLYNLPDTTRMFLCHDYLPSTRDDYVCETDIYTQKSCNIHIHEGMSKL
EFVEMRQARDATLTMPKLILPAIQINMDAGKFPEPESNGQSYLKLPLNYFKA

Sequences:

>Translated_292_residues
MSQQQPNVQEFFDLETNTFSYVVTDIQTQKCAIIDSVLDYDVASATTSTDQADKIIAYIRQNSLSVAWILETHVHADHLT
ASQYLKKQLGGKIAMSRKIAIVQETFSQIYNLDMKYFNLHQSFDYLFEDNEHFKIGDLDAYNIPTPGHTPACLSYVVGDA
VFVGDTLFMPDYGTARCDFPKGSASILFDSVQRLYNLPDTTRMFLCHDYLPSTRDDYVCETDIYTQKSCNIHIHEGMSKL
EFVEMRQARDATLTMPKLILPAIQINMDAGKFPEPESNGQSYLKLPLNYFKA
>Mature_291_residues
SQQQPNVQEFFDLETNTFSYVVTDIQTQKCAIIDSVLDYDVASATTSTDQADKIIAYIRQNSLSVAWILETHVHADHLTA
SQYLKKQLGGKIAMSRKIAIVQETFSQIYNLDMKYFNLHQSFDYLFEDNEHFKIGDLDAYNIPTPGHTPACLSYVVGDAV
FVGDTLFMPDYGTARCDFPKGSASILFDSVQRLYNLPDTTRMFLCHDYLPSTRDDYVCETDIYTQKSCNIHIHEGMSKLE
FVEMRQARDATLTMPKLILPAIQINMDAGKFPEPESNGQSYLKLPLNYFKA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=205, Percent_Identity=26.3414634146341, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=269, Percent_Identity=29.7397769516729, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 33234; Mature: 33103

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQQPNVQEFFDLETNTFSYVVTDIQTQKCAIIDSVLDYDVASATTSTDQADKIIAYIR
CCCCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QNSLSVAWILETHVHADHLTASQYLKKQLGGKIAMSRKIAIVQETFSQIYNLDMKYFNLH
CCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCHHEEEHH
QSFDYLFEDNEHFKIGDLDAYNIPTPGHTPACLSYVVGDAVFVGDTLFMPDYGTARCDFP
HHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCEEEECCEEECCCCCCCEECCC
KGSASILFDSVQRLYNLPDTTRMFLCHDYLPSTRDDYVCETDIYTQKSCNIHIHEGMSKL
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEECCCEECCCCCEEEECCCHHH
EFVEMRQARDATLTMPKLILPAIQINMDAGKFPEPESNGQSYLKLPLNYFKA
HHHHHHHHCCCCCCHHHHHHCEEEEECCCCCCCCCCCCCCEEEEECHHHHCC
>Mature Secondary Structure 
SQQQPNVQEFFDLETNTFSYVVTDIQTQKCAIIDSVLDYDVASATTSTDQADKIIAYIR
CCCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QNSLSVAWILETHVHADHLTASQYLKKQLGGKIAMSRKIAIVQETFSQIYNLDMKYFNLH
CCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCHHEEEHH
QSFDYLFEDNEHFKIGDLDAYNIPTPGHTPACLSYVVGDAVFVGDTLFMPDYGTARCDFP
HHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCEEEECCEEECCCCCCCEECCC
KGSASILFDSVQRLYNLPDTTRMFLCHDYLPSTRDDYVCETDIYTQKSCNIHIHEGMSKL
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEECCCEECCCCCEEEECCCHHH
EFVEMRQARDATLTMPKLILPAIQINMDAGKFPEPESNGQSYLKLPLNYFKA
HHHHHHHHCCCCCCHHHHHHCEEEEECCCCCCCCCCCCCCEEEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]