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The map label for this gene is cfa [H]

Identifier: 50084788

GI number: 50084788

Start: 1626703

End: 1627902

Strand: Direct

Name: cfa [H]

Synonym: ACIAD1630

Alternate gene names: 50084788

Gene position: 1626703-1627902 (Clockwise)

Preceding gene: 50084787

Following gene: 50084789

Centisome position: 45.2

GC content: 40.33

Gene sequence:

>1200_bases
ATGATTAAAACATTTCTTTACGGTGAGCAAGATGCATTACCACTTTGGTTAAGAAGCCTGTTAAAAATTCAGCATGGCCA
GATTACGTTTCGCGGTGCATGGCAGGGTACGGTTGGTGAAGCTTCCGATTTACATGCAATTATTGATGTACATAATCCTG
CGCTAATGCAACTTATCTTTAAAAACGGTGTATTGGGTGCCGCGGAAGGTTATATCCGTGGTGACTGGACCACCGAACAA
CTGGTTGAGTTGATTCAAATCTTGTCACGTAATCGTGACGTCATGGATAAACTCAACCAGAATGTGGTGGCGCAAGCCAG
TCAGGCGGTCTTAAAAGTCTGGTATAAATCTCGTCAAAATTCGCTGAGTGGTAGTCAAAAAAACATTGCCGATCACTATG
ACCTCAGTAATGACTTTTTTAAGTTGTTTCTGGATGAATCAATGATGTATTCCAGTGCGATATTTGAAAATGACAGCATG
TCGTTGGAAGCAGCATCAGATCTAAAAAAAGAACGTATTTGTCAAAAATTACAATTAAAACCACTGGATCATTTGGTGGA
AATTGGAAGTGGGTGGGGCGGATTTGCAATTTACGCTGCACAAAATTATGGTTGTCAGGTGACCACGATTACCATTTCAC
AGGCTCAATACGATGAAGCAGTAGCCAGAGTGAACGCAGCAGGTTTAAGTCATCGAGTAAATGTTCAATTAAAAGATTAT
CGATTACTTGAAGGAAAATTTGACAAACTGGTTTCCATCGAAATGATTGAGGCTGTTGGTGAGCAGTATCTGCCGACTTA
TTTTAATCAATGCCGAAATTTATTAAAGCCACACGGTTTGGCATTAATACAAGCCATTACCATTGAAGATGCGCGCTATC
AAAAAGCACTTAACACAGTAGACTTTATCAAACGCTATATTTTTCCAGGAAGTTTTATTCCCTCAATTAGTGTACTGACT
CAACGGGCATCAGAGCAAAAATTACGTCTCAAGCAACTGGATGATATTGGACTAAGTTACGCCAAAACCTTACATCATTG
GCGAGAACGGTTTCTTGCTCAGAAAGATCAAGTGCTTGCACTGGGTTTTGATGAAAACTTTATCCGTATGTGGGACTTTT
ATCTGTGTTACTGCGAGGGTGGCTTTAAAGAAGGTGTGATTAGTGATGTCCACATGCTGTTTGAAGCAAGTGCCTATTGA

Upstream 100 bases:

>100_bases
TATAAAGATGCTGTTTTCTATTTATGTGCAGGCTTTTCGGCTTTGGCAAAAAAAGATTCCATTCTATCGTCACCCCAAGA
AAAATAAGGATGCATAAGCG

Downstream 100 bases:

>100_bases
TCATCATAAAAGATAGGATAAAGGAGAGAGGCGATGTTATGGAATTTGGTCATCCTGAATTTAGCTATGATGTTGATCAG
TTGGCTCATCGCCACCTTTA

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIKTFLYGEQDALPLWLRSLLKIQHGQITFRGAWQGTVGEASDLHAIIDVHNPALMQLIFKNGVLGAAEGYIRGDWTTEQ
LVELIQILSRNRDVMDKLNQNVVAQASQAVLKVWYKSRQNSLSGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFENDSM
SLEAASDLKKERICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDY
RLLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARYQKALNTVDFIKRYIFPGSFIPSISVLT
QRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEGGFKEGVISDVHMLFEASAY

Sequences:

>Translated_399_residues
MIKTFLYGEQDALPLWLRSLLKIQHGQITFRGAWQGTVGEASDLHAIIDVHNPALMQLIFKNGVLGAAEGYIRGDWTTEQ
LVELIQILSRNRDVMDKLNQNVVAQASQAVLKVWYKSRQNSLSGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFENDSM
SLEAASDLKKERICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDY
RLLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARYQKALNTVDFIKRYIFPGSFIPSISVLT
QRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEGGFKEGVISDVHMLFEASAY
>Mature_399_residues
MIKTFLYGEQDALPLWLRSLLKIQHGQITFRGAWQGTVGEASDLHAIIDVHNPALMQLIFKNGVLGAAEGYIRGDWTTEQ
LVELIQILSRNRDVMDKLNQNVVAQASQAVLKVWYKSRQNSLSGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFENDSM
SLEAASDLKKERICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDY
RLLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARYQKALNTVDFIKRYIFPGSFIPSISVLT
QRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEGGFKEGVISDVHMLFEASAY

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=340, Percent_Identity=35, Blast_Score=178, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI133904226, Length=381, Percent_Identity=36.4829396325459, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45434; Mature: 45434

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTFLYGEQDALPLWLRSLLKIQHGQITFRGAWQGTVGEASDLHAIIDVHNPALMQLIF
CCCEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHH
KNGVLGAAEGYIRGDWTTEQLVELIQILSRNRDVMDKLNQNVVAQASQAVLKVWYKSRQN
HCCCCCCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
SLSGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLK
CCCCCHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
PLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDY
CHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEEECE
RLLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARYQKALNTV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHH
DFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LGFDENFIRMWDFYLCYCEGGFKEGVISDVHMLFEASAY
EECCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIKTFLYGEQDALPLWLRSLLKIQHGQITFRGAWQGTVGEASDLHAIIDVHNPALMQLIF
CCCEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHH
KNGVLGAAEGYIRGDWTTEQLVELIQILSRNRDVMDKLNQNVVAQASQAVLKVWYKSRQN
HCCCCCCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
SLSGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLK
CCCCCHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
PLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDY
CHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEEECE
RLLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARYQKALNTV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHH
DFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LGFDENFIRMWDFYLCYCEGGFKEGVISDVHMLFEASAY
EECCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]