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The map label for this gene is tauD [C]

Identifier: 50084762

GI number: 50084762

Start: 1596513

End: 1597466

Strand: Direct

Name: tauD [C]

Synonym: ACIAD1600

Alternate gene names: 50084762

Gene position: 1596513-1597466 (Clockwise)

Preceding gene: 50084758

Following gene: 50084763

Centisome position: 44.36

GC content: 40.78

Gene sequence:

>954_bases
ATGACCACATTTATTCAGAATCCAACACAGCAACTTCAACTTAGAAAATTGACTGGACGTATCGGGGCTGAAATATCAGG
CATTCACTTGAGCTCTGAGCTTGATTCATCCACAGTTCAGTTTATACACGATGCGCTACTAGAGCATAAAGTACTGTTCT
TCCGTGGCCAGCAACATTTGGGGGATACAGAACAGGAGAAATTTGCAGAATTGTTTGGTTCACCCGTTAAACATCCAACA
GTACCCGCAGCGGATGGTACAGATTTTATTTTTGAACTGGACTCACAAAAAGGTGCACGCGCCAATTCTTGGCATACTGA
TGTCACTTTTGTGGATGCCTATCCTAAAATTAGTATTTTAAGAGGTCTTATCATTCCTGAAACAGGTGGTGATACCACTT
GGGCAAATACTGAAACTGCTTATGAAGATCTTCCTGAACTTTTAAAGCAATTTGCTGAGCAGTTGGTAGCTGTACATTCA
AATGAATATGATTATGGTGGACCAAAACAAAATGTCGAACCAGAACAACTAGAAAGACTGAAAAAAGTTTTTGTATCTAC
CAAGTACGAGACAGAGCATCCAGTGGTTATAGTACATCCAGAAACTGGCAAGAAAAGTCTATTACTCGGGCATTTTTTTA
AACGACTTGTGGGATTCAGTCAAAGTGATTCACAGCTTTTATTTAATATTTTACAAGAAAAAGTAACGCGTCCAGAAAAT
ACCGTGCGCTGGCAATGGCAAGAAGGTGATGTTGTTATTTGGGATAATCGCTCTACCCAGCACTACGCGGTTAACGATTA
TGGCGATCAACATCGGGTTGTACGCCGAATTACACTCGCAGGTGAAGTAACGACTGGCGCACATGGCTTAAAAGGCAAAA
CCACATTACCCAAAGATTTATCAGCAGAACAACTCGAAAAAGCCAAGCTTCACGCTGTGTTAAATGCTAACTAA

Upstream 100 bases:

>100_bases
TATCAAAATAATTTTTTACGTGATGGATTGTCTCGGAAATAACAGAATATACCGCCGTTTCTGATAAAAATTAGTCATAT
TTTTATATCAGGTAATAATT

Downstream 100 bases:

>100_bases
ATAACCATTTTAAGCATCCAAAACGTTACTGTCATTAAGCAGTGACGTTGTATATGTTGTTGAGAAAAACGATATGGCTA
CACTATCAAAACATAACCGA

Product: alkylsulfatase (AtsK)

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTTFIQNPTQQLQLRKLTGRIGAEISGIHLSSELDSSTVQFIHDALLEHKVLFFRGQQHLGDTEQEKFAELFGSPVKHPT
VPAADGTDFIFELDSQKGARANSWHTDVTFVDAYPKISILRGLIIPETGGDTTWANTETAYEDLPELLKQFAEQLVAVHS
NEYDYGGPKQNVEPEQLERLKKVFVSTKYETEHPVVIVHPETGKKSLLLGHFFKRLVGFSQSDSQLLFNILQEKVTRPEN
TVRWQWQEGDVVIWDNRSTQHYAVNDYGDQHRVVRRITLAGEVTTGAHGLKGKTTLPKDLSAEQLEKAKLHAVLNAN

Sequences:

>Translated_317_residues
MTTFIQNPTQQLQLRKLTGRIGAEISGIHLSSELDSSTVQFIHDALLEHKVLFFRGQQHLGDTEQEKFAELFGSPVKHPT
VPAADGTDFIFELDSQKGARANSWHTDVTFVDAYPKISILRGLIIPETGGDTTWANTETAYEDLPELLKQFAEQLVAVHS
NEYDYGGPKQNVEPEQLERLKKVFVSTKYETEHPVVIVHPETGKKSLLLGHFFKRLVGFSQSDSQLLFNILQEKVTRPEN
TVRWQWQEGDVVIWDNRSTQHYAVNDYGDQHRVVRRITLAGEVTTGAHGLKGKTTLPKDLSAEQLEKAKLHAVLNAN
>Mature_316_residues
TTFIQNPTQQLQLRKLTGRIGAEISGIHLSSELDSSTVQFIHDALLEHKVLFFRGQQHLGDTEQEKFAELFGSPVKHPTV
PAADGTDFIFELDSQKGARANSWHTDVTFVDAYPKISILRGLIIPETGGDTTWANTETAYEDLPELLKQFAEQLVAVHSN
EYDYGGPKQNVEPEQLERLKKVFVSTKYETEHPVVIVHPETGKKSLLLGHFFKRLVGFSQSDSQLLFNILQEKVTRPENT
VRWQWQEGDVVIWDNRSTQHYAVNDYGDQHRVVRRITLAGEVTTGAHGLKGKTTLPKDLSAEQLEKAKLHAVLNAN

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=277, Percent_Identity=36.4620938628159, Blast_Score=174, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6322971, Length=299, Percent_Identity=29.0969899665552, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 35750; Mature: 35618

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFIQNPTQQLQLRKLTGRIGAEISGIHLSSELDSSTVQFIHDALLEHKVLFFRGQQHL
CCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECHHHC
GDTEQEKFAELFGSPVKHPTVPAADGTDFIFELDSQKGARANSWHTDVTFVDAYPKISIL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCHHHH
RGLIIPETGGDTTWANTETAYEDLPELLKQFAEQLVAVHSNEYDYGGPKQNVEPEQLERL
HCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
KKVFVSTKYETEHPVVIVHPETGKKSLLLGHFFKRLVGFSQSDSQLLFNILQEKVTRPEN
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
TVRWQWQEGDVVIWDNRSTQHYAVNDYGDQHRVVRRITLAGEVTTGAHGLKGKTTLPKDL
CEEEEEECCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SAEQLEKAKLHAVLNAN
CHHHHHHHHHHEEECCC
>Mature Secondary Structure 
TTFIQNPTQQLQLRKLTGRIGAEISGIHLSSELDSSTVQFIHDALLEHKVLFFRGQQHL
CCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECHHHC
GDTEQEKFAELFGSPVKHPTVPAADGTDFIFELDSQKGARANSWHTDVTFVDAYPKISIL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCHHHH
RGLIIPETGGDTTWANTETAYEDLPELLKQFAEQLVAVHSNEYDYGGPKQNVEPEQLERL
HCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
KKVFVSTKYETEHPVVIVHPETGKKSLLLGHFFKRLVGFSQSDSQLLFNILQEKVTRPEN
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
TVRWQWQEGDVVIWDNRSTQHYAVNDYGDQHRVVRRITLAGEVTTGAHGLKGKTTLPKDL
CEEEEEECCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SAEQLEKAKLHAVLNAN
CHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]