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The map label for this gene is atsA [H]

Identifier: 50084760

GI number: 50084760

Start: 1593688

End: 1595352

Strand: Reverse

Name: atsA [H]

Synonym: ACIAD1598

Alternate gene names: 50084760

Gene position: 1595352-1593688 (Counterclockwise)

Preceding gene: 50084761

Following gene: 50084759

Centisome position: 44.33

GC content: 41.38

Gene sequence:

>1665_bases
ATGACAGATGTAAATATCAAAAACCAACCTAATATTTTATTGATTGTGGCAGATGATTTAGGCTTTTCAGATTTAGGTGC
TTTTGGCGGAGAAATCAATACACCTCATTTGAATCAATTAGCATTAAAGGGCTTAAGACTGACTAATTTTCATACGGCAT
CAACCTGCTCCCCCACTCGTGCGATGTTACTTTCAGGCACAGACCATCATTTAGCTGGTTTAGGGACCATGGCAGAGGCC
CTGACCCCAGAACTCGAAGGTAAAGATGGCTACGAAGGTGTATTAAATAACAAGGTTGCCGCATTACCAGAGTTATTAAA
AGATGCGGGTTACTACACCATAATGTCTGGAAAATGGCATTTGGGTCTAAAACCAGAATATTTTCCAATTCAAAAAGGAT
TTGAACGCTCTTTTGCACTATTACCTGGTGCAGCCAATCATTATCTATTTGAAGCGGATATTCCAGAAGACCAAATTCCA
CGCTTACTTAAGTCAACAAAAGGACTTTATGCAGAGGATGATGAGTTTTCGGAAGAACTGCCTCAAGGGTTTTATTCATC
CGATTATTTTACCACTCGCCTTCTGGATTTTTTACAAGATGATGAGGCACGCCAAGGACGTCCTTTTTTTGCATATTTAC
CTTTCTCTGCACCGCACTGGCCCTTACAGGCACCTCAGGAAGATATCGAACGATATAAAGGACGTTATGCGGATGGCCCT
GTTAAATTGCGTGAACAGCGCCTTGAGAAACTCAAGCAACTTCAATTGGTAGATGATGAAACCACGATTCACCCTGTCCT
TGCGAGAACTCCATTCTGGGATAATCTAAGCCCGTCTGAACGAGAAAAATCATCACGAATTATGGAAGTCTATGCGGCCA
TGGTCGATCGTATGGATCAAAACGTTGGACGTGTAGTGGAATACCTCAAAGATCGAGGGGAATTAGACAATACCATTGTT
ATTTTTCTATCAGATAATGGTGCAGAAGGTGCTCAACTTGAGGCTCTACCCGTCTTTGGCGGCCAACTTAATGAAATTAT
CGAGCAATATTACGACAACAGTATTGATAATATTGGGCGAGCAAACTCATATGTTTGGTACGGAGAACATTGGGCACAAG
CAGCTACTGCTCCTGCTCGCTTATATAAAGCACATACTAGCGAAGGTGGAATTAGAACAGTTTCTTTCATTCACTACGCA
GGGTTTAAACGCCAAAATCAGATTAGTCACGAATTTTTGACAGTCATGGATTTATTACCCACCCTACTAGATTATTTAAA
TATTCAGCATCCAGGTCAGGCGTATAAAGGTCGTCAATTGGTACCGCTACGTGGTCGTTCTATCTTGCCTTATTTACAAG
TACAACAAGACCATATTCACAGTGAAGATCATGTCACAGGCTGGGAATTATTTGGGCAAAAGGCTCTGCGCAAAGGAGAA
TGGAAAGCGCTGTTCATCCCTGCGCCAAATGGCCCAAATCGCTGGCAGCTATATAATCTTAAAGATGATCAAGGCGAAAC
TCAGGATTTGGCAAAAAAATATCCAGAAAAGCTCAATGAATTACTCGAAGAATGGGCAACTTATGTCAAAGAAAATGGTG
TGATTGAAAATGTGCAGCAACGAAGATTATTACAAAATGATCAGCTAGAACCGTTCGAAGCATAA

Upstream 100 bases:

>100_bases
TAATGATATGATTTTATTAGGAGATAACTGTCGCAATAAAAACAGAATAAAAATTTGTCATATTTACACTAAGCGTTTTA
GTCGCTTTGTTGGATAAAAC

Downstream 100 bases:

>100_bases
AAATAACCAAGAGATTCGTATTTAGATTGAACTCAGCCAGCACTCATGCTGGCTTTTAAATTTGCCGCCTAAACAATATT
TTAAAAGCTCTATATTTAAA

Product: arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MTDVNIKNQPNILLIVADDLGFSDLGAFGGEINTPHLNQLALKGLRLTNFHTASTCSPTRAMLLSGTDHHLAGLGTMAEA
LTPELEGKDGYEGVLNNKVAALPELLKDAGYYTIMSGKWHLGLKPEYFPIQKGFERSFALLPGAANHYLFEADIPEDQIP
RLLKSTKGLYAEDDEFSEELPQGFYSSDYFTTRLLDFLQDDEARQGRPFFAYLPFSAPHWPLQAPQEDIERYKGRYADGP
VKLREQRLEKLKQLQLVDDETTIHPVLARTPFWDNLSPSEREKSSRIMEVYAAMVDRMDQNVGRVVEYLKDRGELDNTIV
IFLSDNGAEGAQLEALPVFGGQLNEIIEQYYDNSIDNIGRANSYVWYGEHWAQAATAPARLYKAHTSEGGIRTVSFIHYA
GFKRQNQISHEFLTVMDLLPTLLDYLNIQHPGQAYKGRQLVPLRGRSILPYLQVQQDHIHSEDHVTGWELFGQKALRKGE
WKALFIPAPNGPNRWQLYNLKDDQGETQDLAKKYPEKLNELLEEWATYVKENGVIENVQQRRLLQNDQLEPFEA

Sequences:

>Translated_554_residues
MTDVNIKNQPNILLIVADDLGFSDLGAFGGEINTPHLNQLALKGLRLTNFHTASTCSPTRAMLLSGTDHHLAGLGTMAEA
LTPELEGKDGYEGVLNNKVAALPELLKDAGYYTIMSGKWHLGLKPEYFPIQKGFERSFALLPGAANHYLFEADIPEDQIP
RLLKSTKGLYAEDDEFSEELPQGFYSSDYFTTRLLDFLQDDEARQGRPFFAYLPFSAPHWPLQAPQEDIERYKGRYADGP
VKLREQRLEKLKQLQLVDDETTIHPVLARTPFWDNLSPSEREKSSRIMEVYAAMVDRMDQNVGRVVEYLKDRGELDNTIV
IFLSDNGAEGAQLEALPVFGGQLNEIIEQYYDNSIDNIGRANSYVWYGEHWAQAATAPARLYKAHTSEGGIRTVSFIHYA
GFKRQNQISHEFLTVMDLLPTLLDYLNIQHPGQAYKGRQLVPLRGRSILPYLQVQQDHIHSEDHVTGWELFGQKALRKGE
WKALFIPAPNGPNRWQLYNLKDDQGETQDLAKKYPEKLNELLEEWATYVKENGVIENVQQRRLLQNDQLEPFEA
>Mature_553_residues
TDVNIKNQPNILLIVADDLGFSDLGAFGGEINTPHLNQLALKGLRLTNFHTASTCSPTRAMLLSGTDHHLAGLGTMAEAL
TPELEGKDGYEGVLNNKVAALPELLKDAGYYTIMSGKWHLGLKPEYFPIQKGFERSFALLPGAANHYLFEADIPEDQIPR
LLKSTKGLYAEDDEFSEELPQGFYSSDYFTTRLLDFLQDDEARQGRPFFAYLPFSAPHWPLQAPQEDIERYKGRYADGPV
KLREQRLEKLKQLQLVDDETTIHPVLARTPFWDNLSPSEREKSSRIMEVYAAMVDRMDQNVGRVVEYLKDRGELDNTIVI
FLSDNGAEGAQLEALPVFGGQLNEIIEQYYDNSIDNIGRANSYVWYGEHWAQAATAPARLYKAHTSEGGIRTVSFIHYAG
FKRQNQISHEFLTVMDLLPTLLDYLNIQHPGQAYKGRQLVPLRGRSILPYLQVQQDHIHSEDHVTGWELFGQKALRKGEW
KALFIPAPNGPNRWQLYNLKDDQGETQDLAKKYPEKLNELLEEWATYVKENGVIENVQQRRLLQNDQLEPFEA

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=564, Percent_Identity=26.063829787234, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI38569405, Length=571, Percent_Identity=25.0437828371278, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI59797060, Length=558, Percent_Identity=26.3440860215054, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI38569407, Length=419, Percent_Identity=28.1622911694511, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4503899, Length=454, Percent_Identity=28.1938325991189, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI146229331, Length=541, Percent_Identity=27.1719038817006, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI146229329, Length=541, Percent_Identity=27.1719038817006, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI6005990, Length=541, Percent_Identity=27.1719038817006, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI146229324, Length=541, Percent_Identity=27.1719038817006, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI45430057, Length=536, Percent_Identity=24.8134328358209, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI53831991, Length=455, Percent_Identity=23.7362637362637, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI157266309, Length=141, Percent_Identity=34.7517730496454, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI58743319, Length=140, Percent_Identity=35.7142857142857, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI31742482, Length=141, Percent_Identity=34.7517730496454, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI71852586, Length=148, Percent_Identity=33.7837837837838, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI71852584, Length=148, Percent_Identity=33.7837837837838, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790233, Length=443, Percent_Identity=26.1851015801354, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790112, Length=322, Percent_Identity=26.7080745341615, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533416, Length=537, Percent_Identity=24.5810055865922, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI115533418, Length=530, Percent_Identity=24.1509433962264, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17559078, Length=143, Percent_Identity=31.4685314685315, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666109, Length=483, Percent_Identity=27.9503105590062, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281366397, Length=440, Percent_Identity=26.1363636363636, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281366395, Length=440, Percent_Identity=26.1363636363636, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24666163, Length=440, Percent_Identity=26.1363636363636, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281363223, Length=492, Percent_Identity=25.609756097561, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24666175, Length=488, Percent_Identity=24.1803278688525, Blast_Score=122, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 63027; Mature: 62895

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVNIKNQPNILLIVADDLGFSDLGAFGGEINTPHLNQLALKGLRLTNFHTASTCSPTR
CCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHHHHHHCCCEEECCCCCCCCCCCH
AMLLSGTDHHLAGLGTMAEALTPELEGKDGYEGVLNNKVAALPELLKDAGYYTIMSGKWH
HHEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCEEEECCEEE
LGLKPEYFPIQKGFERSFALLPGAANHYLFEADIPEDQIPRLLKSTKGLYAEDDEFSEEL
ECCCCCCCCCHHCCCCHHEECCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHH
PQGFYSSDYFTTRLLDFLQDDEARQGRPFFAYLPFSAPHWPLQAPQEDIERYKGRYADGP
CCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCC
VKLREQRLEKLKQLQLVDDETTIHPVLARTPFWDNLSPSEREKSSRIMEVYAAMVDRMDQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NVGRVVEYLKDRGELDNTIVIFLSDNGAEGAQLEALPVFGGQLNEIIEQYYDNSIDNIGR
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHCCC
ANSYVWYGEHWAQAATAPARLYKAHTSEGGIRTVSFIHYAGFKRQNQISHEFLTVMDLLP
CCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHH
TLLDYLNIQHPGQAYKGRQLVPLRGRSILPYLQVQQDHIHSEDHVTGWELFGQKALRKGE
HHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
WKALFIPAPNGPNRWQLYNLKDDQGETQDLAKKYPEKLNELLEEWATYVKENGVIENVQQ
CCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RRLLQNDQLEPFEA
HHHHHCCCCCCCCC
>Mature Secondary Structure 
TDVNIKNQPNILLIVADDLGFSDLGAFGGEINTPHLNQLALKGLRLTNFHTASTCSPTR
CCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHHHHHHCCCEEECCCCCCCCCCCH
AMLLSGTDHHLAGLGTMAEALTPELEGKDGYEGVLNNKVAALPELLKDAGYYTIMSGKWH
HHEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCEEEECCEEE
LGLKPEYFPIQKGFERSFALLPGAANHYLFEADIPEDQIPRLLKSTKGLYAEDDEFSEEL
ECCCCCCCCCHHCCCCHHEECCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHH
PQGFYSSDYFTTRLLDFLQDDEARQGRPFFAYLPFSAPHWPLQAPQEDIERYKGRYADGP
CCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCC
VKLREQRLEKLKQLQLVDDETTIHPVLARTPFWDNLSPSEREKSSRIMEVYAAMVDRMDQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NVGRVVEYLKDRGELDNTIVIFLSDNGAEGAQLEALPVFGGQLNEIIEQYYDNSIDNIGR
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHCCC
ANSYVWYGEHWAQAATAPARLYKAHTSEGGIRTVSFIHYAGFKRQNQISHEFLTVMDLLP
CCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHH
TLLDYLNIQHPGQAYKGRQLVPLRGRSILPYLQVQQDHIHSEDHVTGWELFGQKALRKGE
HHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
WKALFIPAPNGPNRWQLYNLKDDQGETQDLAKKYPEKLNELLEEWATYVKENGVIENVQQ
CCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RRLLQNDQLEPFEA
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]