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The map label for this gene is csd1 [H]

Identifier: 50084744

GI number: 50084744

Start: 1573644

End: 1575596

Strand: Reverse

Name: csd1 [H]

Synonym: ACIAD1582

Alternate gene names: 50084744

Gene position: 1575596-1573644 (Counterclockwise)

Preceding gene: 50084745

Following gene: 50084743

Centisome position: 43.78

GC content: 43.22

Gene sequence:

>1953_bases
ATGACTACCCAGTTAACTACAAATAATATTACGGGTAGTCCAAACAGTGAAGTGGCTGGAATTTCACCCCCAGCCAACTT
TCCTGATGAAGCCACCCTATCCCGTCTCGCAAGCGAGTTTTTTGCAGCCTTACCAAGTTCTGGCGGTCATGCATCTGGAC
TTAATCTGGACCTACCCAATGTCGGCACTCCACCACATGCTCCACAACCTGTCGAACCTGTGGCAGCGTTAAGTGGACGT
GCTCCAAATATTGCTTACCAGAAAAGTTTGAATCCTGAATACCCTGAGCATATACCCAATTATCCAGATTATCCTGAACG
TCGTGCTATTGCTTCTTCTCCTGTGATTGGAGGGGCAAACTTGCCACGACCACCCATTGAACCACATTTTCCACAAGCAA
TTCATCAGCAGCCAAATGTCCCTTTGGTAAGCCCAAATGTGCCATTAAATCGTGAACAATCGCCTTTTTATTTCCTAGAT
GATCTTGCGTCTCCGACAAAATCAAGTTCAGATTTTGATGTGACAAATCATTCAACACCCCAATCATCTCAGTTACCTCA
AGGAGAAAAACTAAACGCCCTGTTGCGTGAAGATCGTCCAAATATCACTACTGCACATCAACCACATACCACATCATCAG
GATTCTACTTTCTTGATATTCCAAAAGTTGAACAGTCATATCAGAACTATGTGCCGTCTCAATCCACTTTTGTAACCAAT
AGTGCTCAGCCCTTAGACATACACGCCATACGGCGCGATTTTCCAATCCTTCAGGAACGTATTAATGGGCGGCCTCTGGT
ATGGTTTGATAATGCAGCCACGACTCAAAAACCGCAATCTGTGATTGATCGTATTGCTTATTTTTATCAACATGAAAATT
CCAATATTCATCGTGCTGCACATGAACTTGCAGCACGTGCAACCGATGCTTATGAACATGCACGTAATGTAGTCGCTCGT
TTTATTGGGGCAAAATCATCCAAGGAAATCATTTTTGTTCGTGGGACCACCGAAGGCATTAATTTAATCGCCAAAACCTG
GGGCGAACAAAATATTGGTGAAGGTGATGAAATTATTGTCTCTCATCTGGAACATCATGCGAATATCGTACCCTGGTATC
AGCTCAGCAAAAAAACTGGAGCCAAATTGCGGGTTATTCCTGTGGATGATACAGGTCAAATCCTTCTTGAGGAGCTACCT
AAACTTATTAATGAACGTACTAAACTGGTCTCAATCACTCAAGTTTCAAATGCTTTAGGAACGGTCACTCCCGTCGCTGA
GGTCATTAAAATTGCTCATAGCAAAGGAGTTCGTGTATTGGTGGATGGTGCTCAATCTGTTTCGCACATGCCAACCGATG
TACAAGCGATTGATGCCGATTTCTTTGTGTTCTCTGGACATAAAGTATTTGGGCCAACAGGCATTGGTGCTATTTATGCC
AAACCTGAAATTCTGGAGACAATGCCAGTATGGGAAGGTGGTGGTAATATGATTCAAGATGTGACATTTGAACAAGTCAT
TTACCAACCTGCCCCGAATAAATTTGAAGCAGGTACTGGTAACATTGCCGATGCCGTGGGTCTAGGGGCTGCGCTGGAAT
ATGTCGAACGGATTGGTATCCACAATATTGCCCGTTATGAGCATGATTTACTTGAATATGGTCAACATGCCTTAAGCAGT
GTAACTGGCTTGCGGCCAATTGGAACAGCAAAAAATAAGGCCAGTGTGATGTCATTCATCCTTGATGGTTATTCTACTGA
ACAAGTAGGCAAAGCTCTTAACCAACATGGTATTGCAGTTCGTTCAGGACATCATTGTGCTCAGCCTATTCTACGCCGTT
TTGGTGTGGAGCAAACCGTACGCCCTTCGTTGGCTTTTTATAATACTCACGAAGAAATCGACTTAATGATTTCAGTCTTA
AATCAACTCGCTAGAAATAAACGGAGTATTTAA

Upstream 100 bases:

>100_bases
AATGCGATTGCATCCTATCTGATTTCTTTATATTGCTCACTTGCAGTATTAACAGAAGATGCATTGGCTGTATTAGATGA
TGTGGAGATCGATAAATATC

Downstream 100 bases:

>100_bases
AACCTTAACACGTAGAAAAAGACAGTATTAAAGCCATCTTTTTCTACGTCACCTCTATTTCGGATAAAAAATTGACTAGA
AAAATAAGAGGCCTAGAGTC

Product: cysteine desulfurase 1 (Csd)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MTTQLTTNNITGSPNSEVAGISPPANFPDEATLSRLASEFFAALPSSGGHASGLNLDLPNVGTPPHAPQPVEPVAALSGR
APNIAYQKSLNPEYPEHIPNYPDYPERRAIASSPVIGGANLPRPPIEPHFPQAIHQQPNVPLVSPNVPLNREQSPFYFLD
DLASPTKSSSDFDVTNHSTPQSSQLPQGEKLNALLREDRPNITTAHQPHTTSSGFYFLDIPKVEQSYQNYVPSQSTFVTN
SAQPLDIHAIRRDFPILQERINGRPLVWFDNAATTQKPQSVIDRIAYFYQHENSNIHRAAHELAARATDAYEHARNVVAR
FIGAKSSKEIIFVRGTTEGINLIAKTWGEQNIGEGDEIIVSHLEHHANIVPWYQLSKKTGAKLRVIPVDDTGQILLEELP
KLINERTKLVSITQVSNALGTVTPVAEVIKIAHSKGVRVLVDGAQSVSHMPTDVQAIDADFFVFSGHKVFGPTGIGAIYA
KPEILETMPVWEGGGNMIQDVTFEQVIYQPAPNKFEAGTGNIADAVGLGAALEYVERIGIHNIARYEHDLLEYGQHALSS
VTGLRPIGTAKNKASVMSFILDGYSTEQVGKALNQHGIAVRSGHHCAQPILRRFGVEQTVRPSLAFYNTHEEIDLMISVL
NQLARNKRSI

Sequences:

>Translated_650_residues
MTTQLTTNNITGSPNSEVAGISPPANFPDEATLSRLASEFFAALPSSGGHASGLNLDLPNVGTPPHAPQPVEPVAALSGR
APNIAYQKSLNPEYPEHIPNYPDYPERRAIASSPVIGGANLPRPPIEPHFPQAIHQQPNVPLVSPNVPLNREQSPFYFLD
DLASPTKSSSDFDVTNHSTPQSSQLPQGEKLNALLREDRPNITTAHQPHTTSSGFYFLDIPKVEQSYQNYVPSQSTFVTN
SAQPLDIHAIRRDFPILQERINGRPLVWFDNAATTQKPQSVIDRIAYFYQHENSNIHRAAHELAARATDAYEHARNVVAR
FIGAKSSKEIIFVRGTTEGINLIAKTWGEQNIGEGDEIIVSHLEHHANIVPWYQLSKKTGAKLRVIPVDDTGQILLEELP
KLINERTKLVSITQVSNALGTVTPVAEVIKIAHSKGVRVLVDGAQSVSHMPTDVQAIDADFFVFSGHKVFGPTGIGAIYA
KPEILETMPVWEGGGNMIQDVTFEQVIYQPAPNKFEAGTGNIADAVGLGAALEYVERIGIHNIARYEHDLLEYGQHALSS
VTGLRPIGTAKNKASVMSFILDGYSTEQVGKALNQHGIAVRSGHHCAQPILRRFGVEQTVRPSLAFYNTHEEIDLMISVL
NQLARNKRSI
>Mature_649_residues
TTQLTTNNITGSPNSEVAGISPPANFPDEATLSRLASEFFAALPSSGGHASGLNLDLPNVGTPPHAPQPVEPVAALSGRA
PNIAYQKSLNPEYPEHIPNYPDYPERRAIASSPVIGGANLPRPPIEPHFPQAIHQQPNVPLVSPNVPLNREQSPFYFLDD
LASPTKSSSDFDVTNHSTPQSSQLPQGEKLNALLREDRPNITTAHQPHTTSSGFYFLDIPKVEQSYQNYVPSQSTFVTNS
AQPLDIHAIRRDFPILQERINGRPLVWFDNAATTQKPQSVIDRIAYFYQHENSNIHRAAHELAARATDAYEHARNVVARF
IGAKSSKEIIFVRGTTEGINLIAKTWGEQNIGEGDEIIVSHLEHHANIVPWYQLSKKTGAKLRVIPVDDTGQILLEELPK
LINERTKLVSITQVSNALGTVTPVAEVIKIAHSKGVRVLVDGAQSVSHMPTDVQAIDADFFVFSGHKVFGPTGIGAIYAK
PEILETMPVWEGGGNMIQDVTFEQVIYQPAPNKFEAGTGNIADAVGLGAALEYVERIGIHNIARYEHDLLEYGQHALSSV
TGLRPIGTAKNKASVMSFILDGYSTEQVGKALNQHGIAVRSGHHCAQPILRRFGVEQTVRPSLAFYNTHEEIDLMISVLN
QLARNKRSI

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=423, Percent_Identity=27.1867612293144, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI156713448, Length=388, Percent_Identity=27.0618556701031, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1787970, Length=402, Percent_Identity=50.2487562189055, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1789175, Length=393, Percent_Identity=40.2035623409669, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI48994898, Length=395, Percent_Identity=27.3417721518987, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25143064, Length=215, Percent_Identity=30.6976744186047, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=377, Percent_Identity=24.9336870026525, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319831, Length=235, Percent_Identity=34.0425531914894, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI20129463, Length=428, Percent_Identity=30.1401869158879, Blast_Score=129, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 71120; Mature: 70989

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQLTTNNITGSPNSEVAGISPPANFPDEATLSRLASEFFAALPSSGGHASGLNLDLPN
CCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCC
VGTPPHAPQPVEPVAALSGRAPNIAYQKSLNPEYPEHIPNYPDYPERRAIASSPVIGGAN
CCCCCCCCCCCCHHHHHCCCCCCCEECCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCC
LPRPPIEPHFPQAIHQQPNVPLVSPNVPLNREQSPFYFLDDLASPTKSSSDFDVTNHSTP
CCCCCCCCCCCHHHHCCCCCCEECCCCCCCCCCCCCEEHHHHCCCCCCCCCCCCCCCCCC
QSSQLPQGEKLNALLREDRPNITTAHQPHTTSSGFYFLDIPKVEQSYQNYVPSQSTFVTN
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEC
SAQPLDIHAIRRDFPILQERINGRPLVWFDNAATTQKPQSVIDRIAYFYQHENSNIHRAA
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
HELAARATDAYEHARNVVARFIGAKSSKEIIFVRGTTEGINLIAKTWGEQNIGEGDEIIV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCHHHHH
SHLEHHANIVPWYQLSKKTGAKLRVIPVDDTGQILLEELPKLINERTKLVSITQVSNALG
HHHHHHCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHH
TVTPVAEVIKIAHSKGVRVLVDGAQSVSHMPTDVQAIDADFFVFSGHKVFGPTGIGAIYA
HHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCHHEECCCEEEEECCEEECCCCCCEEEC
KPEILETMPVWEGGGNMIQDVTFEQVIYQPAPNKFEAGTGNIADAVGLGAALEYVERIGI
CCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCH
HNIARYEHDLLEYGQHALSSVTGLRPIGTAKNKASVMSFILDGYSTEQVGKALNQHGIAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEE
RSGHHCAQPILRRFGVEQTVRPSLAFYNTHEEIDLMISVLNQLARNKRSI
ECCCHHHHHHHHHCCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTQLTTNNITGSPNSEVAGISPPANFPDEATLSRLASEFFAALPSSGGHASGLNLDLPN
CCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCC
VGTPPHAPQPVEPVAALSGRAPNIAYQKSLNPEYPEHIPNYPDYPERRAIASSPVIGGAN
CCCCCCCCCCCCHHHHHCCCCCCCEECCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCC
LPRPPIEPHFPQAIHQQPNVPLVSPNVPLNREQSPFYFLDDLASPTKSSSDFDVTNHSTP
CCCCCCCCCCCHHHHCCCCCCEECCCCCCCCCCCCCEEHHHHCCCCCCCCCCCCCCCCCC
QSSQLPQGEKLNALLREDRPNITTAHQPHTTSSGFYFLDIPKVEQSYQNYVPSQSTFVTN
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEC
SAQPLDIHAIRRDFPILQERINGRPLVWFDNAATTQKPQSVIDRIAYFYQHENSNIHRAA
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
HELAARATDAYEHARNVVARFIGAKSSKEIIFVRGTTEGINLIAKTWGEQNIGEGDEIIV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCHHHHH
SHLEHHANIVPWYQLSKKTGAKLRVIPVDDTGQILLEELPKLINERTKLVSITQVSNALG
HHHHHHCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHH
TVTPVAEVIKIAHSKGVRVLVDGAQSVSHMPTDVQAIDADFFVFSGHKVFGPTGIGAIYA
HHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCHHEECCCEEEEECCEEECCCCCCEEEC
KPEILETMPVWEGGGNMIQDVTFEQVIYQPAPNKFEAGTGNIADAVGLGAALEYVERIGI
CCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCH
HNIARYEHDLLEYGQHALSSVTGLRPIGTAKNKASVMSFILDGYSTEQVGKALNQHGIAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEE
RSGHHCAQPILRRFGVEQTVRPSLAFYNTHEEIDLMISVLNQLARNKRSI
ECCCHHHHHHHHHCCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]